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Showing 1–24 of 679 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Tooth Diseases Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Study to Evaluate the Safety and Efficacy of an Oxalate Strip on Adjacent Teeth With Dentinal Hypersensitivity

NCT02293044
View directory record Official record
Conditions
Dentin Sensitivity
Interventions
Crest® Sensi-Stop™ Strips
Device
Lead sponsor
Procter and Gamble
Industry
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014
U.S. locations
1
States / cities
Mason, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 24, 2019 · Synced Sep 10, 2026, 4:16 AM EDT
Completed No phase listed Observational

Clinical Evaluation of a Self-etch Adhesive Using a Selective Etch Technique

NCT01369134
View directory record Official record
Conditions
Dental Caries
Interventions
Adper Easy Bond Self-etch dental adhesive
Device
Lead sponsor
Solventum US LLC
Industry
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Oct 1, 2024 · Synced Sep 10, 2026, 4:16 AM EDT
Completed No phase listed Observational Results available

PCP Use of a Gene Expression Test (Corus CAD or ASGES) in Coronary Artery Disease Diagnosis

NCT01594411
View directory record Official record
Conditions
Chest Pain, Cardiovascular Diseases, Angina Pectoris, Coronary Artery Disease, CAD, CVD, CHD, Coronary Heart Disease
Interventions
Corus CAD
Diagnostic Test
Lead sponsor
CardioDx
Industry
Eligibility
21 Years and older
Enrollment
251 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
4
States / cities
Suwanee, Georgia • Baton Rouge, Louisiana • Charlotte, North Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Jan 30, 2019 · Synced Sep 10, 2026, 4:16 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Clinical Effectiveness of Late Maxillary Protraction for Cleft Lip and Palate

NCT02789787
View directory record Official record
Conditions
Cleft Lip and Palate
Interventions
Maxillary Protraction, Orthognathic Surgery
Procedure
Lead sponsor
University of Southern California
Other
Eligibility
11 Years to 21 Years
Enrollment
117 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2021
U.S. locations
2
States / cities
Los Angeles, California • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Oct 10, 2021 · Synced Sep 10, 2026, 4:16 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Comparison Study of Hypersensitivity Treatment

NCT05768373
View directory record Official record
Conditions
Dentin Hypersensitivity
Interventions
3M™ Clinpro™ Fluoride Aqueous Solution, 3M™ Vanish™
Device
Lead sponsor
Solventum US LLC
Industry
Eligibility
18 Years and older
Enrollment
101 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Feb 6, 2025 · Synced Sep 10, 2026, 4:16 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Phase 2 Study to Evaluate the Microbiology and Safety of C16G2 Administered to Adult and Adolescent Dental Subjects

NCT02594254
View directory record Official record
Conditions
Dental Caries
Interventions
C16G2 Gel, Placebo
Drug · Other
Lead sponsor
Armata Pharmaceuticals, Inc.
Industry
Eligibility
12 Years to 75 Years
Enrollment
135 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
10
States / cities
Imperial Beach, California • Indianapolis, Indiana • Boston, Massachusetts + 6 more
Source: ClinicalTrials.gov public record
Updated Jul 31, 2019 · Synced Sep 10, 2026, 4:16 AM EDT
Active, not recruiting No phase listed Observational

A Prospective Natural History and Outcome Measure Discovery Study of Charcot-Marie-Tooth Disease, Type 4J

NCT06151600
View directory record Official record
Conditions
Peripheral Neuropathy, Neuro-Degenerative Disease, Neuromuscular Diseases
Interventions
Not listed
Lead sponsor
Elpida Therapeutics SPC
Industry
Eligibility
Not listed
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2032
U.S. locations
3
States / cities
San Francisco, California • Iowa City, Iowa • Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jul 7, 2026 · Synced Sep 10, 2026, 4:16 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Clinical Study to Investigate the Antihypersensitivity Efficacy of a Novel Dentifrice

NCT07215767
View directory record Official record
Conditions
Dentin Hypersensitivity
Interventions
Stannous fluoride and Potassium nitrate Dentifrice, Stannous fluoride Dentifrice, Potassium nitrate Dentifrice, Vehicle Dentifrice
Drug
Lead sponsor
HALEON
Industry
Eligibility
12 Years to 65 Years
Enrollment
688 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
3
States / cities
Melbourne, Florida • Fort Wayne, Indiana • Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated Aug 24, 2026 · Synced Sep 10, 2026, 4:16 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Efficacy of Plaque Removal of a Novel Brushing Device

NCT05038293
View directory record Official record
Conditions
Dental Plaque
Interventions
Automated mouthpiece-based toothbrush, Manual toothbrush
Device
Lead sponsor
University of Washington
Other
Eligibility
5 Years to 17 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Mar 30, 2023 · Synced Sep 10, 2026, 4:16 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Postoperative Pain and Healing in Teeth Treated With GentleWave or EndoActivator

NCT04552132
View directory record Official record
Conditions
Symptomatic Irreversible Pulpitis, Apical Periodontitis
Interventions
Multisonic vs Sonic activation of irrigants
Device
Lead sponsor
St. Louis University
Other
Eligibility
18 Years and older
Enrollment
63 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jun 14, 2023 · Synced Sep 10, 2026, 4:16 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Effects of Fish Oil Supplementation on the Brain Health of Collegiate Football Athletes

NCT04796207
View directory record Official record
Conditions
Traumatic Brain Injury (TBI), Chronic Traumatic Encephalopathy (CTE)
Interventions
Fish Oil (DPA+EPA 2:1 ratio) Capsules, High Oleic Safflower Oil Capsules
Dietary Supplement
Lead sponsor
University of Arizona
Other
Eligibility
18 Years to 25 Years · Male only
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated May 8, 2025 · Synced Sep 10, 2026, 4:16 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

A Study of Acetaminophen for Post Surgical Dental Pain

NCT04018612
View directory record Official record
Conditions
Pain, Postoperative, Dental Pain
Interventions
Acetaminophen, Placebo
Drug · Other
Lead sponsor
Nevakar, Inc.
Industry
Eligibility
17 Years to 55 Years
Enrollment
110 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Mar 28, 2022 · Synced Sep 10, 2026, 4:16 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Assessing a New Jaw Support Device During Third Molar Extractions

NCT03975920
View directory record Official record
Conditions
Impacted Third Molar Tooth, Temporomandibular Disorder
Interventions
The Restful Jaw Device
Device
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 30 Years
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
4
States / cities
Burnsville, Minnesota • Eden Prairie, Minnesota • Minneapolis, Minnesota + 1 more
Source: ClinicalTrials.gov public record
Updated Jun 5, 2022 · Synced Sep 10, 2026, 4:16 AM EDT
Completed Not applicable Interventional

Wheelchair Maintenance Training Program

NCT03909061
View directory record Official record
Conditions
Remote Maintenance Training Program
Interventions
Wheelchair Maintenance Training
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
Not listed
Enrollment
187 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 11, 2024 · Synced Sep 10, 2026, 4:16 AM EDT
Completed Not applicable Interventional

Novel Treatment for Dental Ankylosis

NCT05695105
View directory record Official record
Conditions
Dental Ankylosis
Interventions
Electric Toothbrush-Generated Vibration, Mini-Implant-Assisted Orthodontic Treatment
Device
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
6 Years to 30 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Newark, New Jersey
Source: ClinicalTrials.gov public record
Updated Jan 14, 2026 · Synced Sep 10, 2026, 4:16 AM EDT
Recruiting Phase 1Phase 2 Interventional

Study of Intrathecal ELP-02 for Charcot-Marie-Tooth Disease Type 4J (CMT4J)

NCT07447557
View directory record Official record
Conditions
Charcot-Marie-Tooth Disease Type 4J
Interventions
ELP-02
Genetic
Lead sponsor
Elpida Therapeutics SPC
Industry
Eligibility
3 Years to 20 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2032
U.S. locations
2
States / cities
Palo Alto, California • Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Sep 8, 2026 · Synced Sep 10, 2026, 4:16 AM EDT
Completed Phase 3 Interventional

Ibuprofen Liquid Capsules 2 x 200 mg Efficacy and PK/PD Study in Surgical Removal of Impacted Third Molars

NCT05484401
View directory record Official record
Conditions
Tooth, Impacted, Tooth Diseases, Stomatognathic Diseases
Interventions
Ibuprofen 200Mg Oral Cap, Ibuprofen 200Mg Oral Tablet, Placebo Liquid Capsule, Placebo Tablets
Drug · Other
Lead sponsor
Reckitt Benckiser Healthcare (UK) Limited
Industry
Eligibility
16 Years to 55 Years
Enrollment
294 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jun 21, 2023 · Synced Sep 10, 2026, 4:16 AM EDT
Active, not recruiting Phase 1Phase 2 Interventional

Treatment of Charcot-Marie-Tooth Disease, Axonal, Type 2S (CMT2S) in an Individual Patient

NCT07223632
View directory record Official record
Conditions
Charcot Marie Tooth Disease (CMT), Neuromuscular Diseases (NMD)
Interventions
VCA-894A
Drug
Lead sponsor
Vanda Pharmaceuticals
Industry
Eligibility
Female only
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Aug 18, 2026 · Synced Sep 10, 2026, 4:16 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

BEhavioral EConomics for Oral Health iNnovation Pilot Trial

NCT03862443
View directory record Official record
Conditions
Toothbrushing, Dental Plaque, Parent-Child Relations, Oral Hygiene, Dental Caries
Interventions
Fixed Incentive, Drawing Incentive
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
6 Months to 42 Months
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Santa Monica, California
Source: ClinicalTrials.gov public record
Updated Mar 4, 2019 · Synced Sep 10, 2026, 4:16 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Zirconia-based Primary Anterior Crowns With Retention Grooves Versus Without Retention Grooves

NCT06354647
View directory record Official record
Conditions
Dental Caries, Tooth Decay
Interventions
Zirconia-based primary anterior crowns with retention grooves, Zirconia-based primary anterior crowns without retention grooves
Procedure
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
2 Years to 6 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Feb 25, 2025 · Synced Sep 10, 2026, 4:16 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

DPBRN Prevalence of Questionable Occlusal Caries Lesions

NCT01201447
View directory record Official record
Conditions
Dental Caries
Interventions
Not listed
Lead sponsor
Dental Practice-Based Research Network
Network
Eligibility
6 Years and older
Enrollment
2,624 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2010
U.S. locations
6
States / cities
Birmingham, Alabama • Gainesville, Florida • Minneapolis, Minnesota + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 3, 2011 · Synced Sep 10, 2026, 4:16 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Precision of Complete-arch Digital Implant Impressions With Intraoral Scanning Versus Photogrammetry

NCT05972148
View directory record Official record
Conditions
Edentulous Jaw
Interventions
Digital scanning, Photogrammetry
Other
Lead sponsor
William Negreiros
Other
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 2, 2023 · Synced Sep 10, 2026, 4:16 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Primer Aligner Study

NCT02550938
View directory record Official record
Conditions
Malocclusion
Interventions
Invisalign
Device
Lead sponsor
Align Technology, Inc.
Industry
Eligibility
18 Years and older
Enrollment
253 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2020
U.S. locations
13
States / cities
Anthem, Arizona • Napa, California • Oakland, California + 10 more
Source: ClinicalTrials.gov public record
Updated Feb 2, 2021 · Synced Sep 10, 2026, 4:16 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

A Study Evaluating Oral-Health-Related Quality of Life and Treatment Patterns Among Dentin Hypersensitivity Sufferers

NCT07337109
View directory record Official record
Conditions
Dentin Hypersensitivity
Interventions
Not listed
Lead sponsor
HALEON
Industry
Eligibility
18 Years and older
Enrollment
375 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated Apr 27, 2026 · Synced Sep 10, 2026, 4:16 AM EDT