Independent directory Public ClinicalTrials.gov records United States
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Showing 457–480 of 692 matching trials from the live ClinicalTrials.gov search.
Conditions
Dental Caries
Interventions
Dispersed phase amalgam restoration /composite restoration
Device
Lead sponsor
Carelon Research
Other
Eligibility
6 Years to 10 Years
Enrollment
534 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1997 – 2005
U.S. locations
1
States / cities
Watertown, Massachusetts
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Brief Interventions to Improve Behavior Outcomes and Prevent Cavities

NCT06588725
Conditions
Parenting, Cavity, Dental, Child Behavior
Interventions
Play Nicely, Cavity Prevention Handout
Behavioral
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
9 Months to 3 Years
Enrollment
750 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2035
U.S. locations
1
States / cities
Nashville, Tennessee
Completed Not applicable Interventional Results available

TetricCAD Crown Clinical Study

NCT03716817
Conditions
Fractured Tooth, Decayed Tooth, Unsatisfactory Restoration of Tooth
Interventions
Tetric CAD
Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
Ann Arbor, Michigan
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Birth to Three - Cavity Free

NCT05756413
Conditions
Caries,Dental
Interventions
Self-determination theory
Behavioral
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 45 Years
Enrollment
1,268 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
16
States / cities
Anamosa, Iowa • Belle Plaine, Iowa • Cedar Rapids, Iowa + 11 more
Enrolling by invitation No phase listed Observational

Multi-Institutional IMPACT Validation

NCT06850857
Conditions
Facial Injuries, Mandible Fracture, Le Fort, Zygomaticomaxillary Complex Fracture, Nasal Fracture, Orbital Fractures, Zygoma Fracture, Orbital Floor Fracture, Facial Laceration
Interventions
IMPACT-G Module, IMPACT-N Module, IMPACT-O Module, IMPACT-J Module, 15D Control Survey
Other
Lead sponsor
University of Tennessee
Other
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
3
States / cities
Sacramento, California • San Francisco, California • Memphis, Tennessee
Conditions
Furcation Defects, Periodontitis, Alveolar Bone Loss Beyond Furcation
Interventions
bioresorbable membrane alonewill be used for regeneration of the periodontium(control)
Procedure
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Houston, Texas
Completed No phase listed Interventional Accepts healthy volunteers Results available

A Clinical Study to Evaluate Effects of an Oral Rinse on Plaque and Gingivitis

NCT03421145
Conditions
Plaque
Interventions
3M™ Oral Rinse, Vehicle Control Oral Rinse, PerioShield™ Oral Health Rinse, Water
Device · Other
Lead sponsor
Solventum US LLC
Industry
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Loma Linda, California
Conditions
Multiple Sclerosis
Interventions
ofatumumab with PRF, ofatumumab with AI
Combination Product
Lead sponsor
Novartis Pharmaceuticals
Industry
Eligibility
18 Years to 55 Years
Enrollment
284 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
13
States / cities
Fullerton, California • Aurora, Colorado • Basalt, Colorado + 9 more
Conditions
Peripheral Neuropathy, Neuro-Degenerative Disease, Neuromuscular Diseases
Interventions
Not listed
Lead sponsor
Elpida Therapeutics SPC
Industry
Eligibility
Not listed
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2032
U.S. locations
3
States / cities
San Francisco, California • Iowa City, Iowa • Dallas, Texas
Conditions
Denture Stomatitis, Wear of Denture Teeth
Interventions
PECVD coating
Device
Lead sponsor
University of Florida
Other
Eligibility
21 Years to 80 Years
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Gainesville, Florida
Conditions
Plaque, Dental
Interventions
Dentifrices
Drug
Lead sponsor
Church & Dwight Company, Inc.
Industry
Eligibility
18 Years to 69 Years
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Fort Wayne, Indiana
Conditions
Tooth Loss
Interventions
Anorganic Bovine Bone Graft Material, Collagen Membrane, Shelta Platform Switching Premium Implants, Shelta Platform Matching Premium Implants
Device
Lead sponsor
NYU College of Dentistry
Other
Eligibility
18 Years to 70 Years
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2022
U.S. locations
1
States / cities
New York, New York
Conditions
Tooth Loss
Interventions
Bone Graft Material
Device
Lead sponsor
Institut Straumann AG
Industry
Eligibility
18 Years to 80 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Yardley, Pennsylvania
Conditions
Dentin Sensitivity
Interventions
Crest® Sensi-Stop™ Strips
Device
Lead sponsor
Procter and Gamble
Industry
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014
U.S. locations
1
States / cities
Mason, Ohio
Conditions
Pain, Electroencephalography, Toothache
Interventions
EEG EMOTIV
Device
Lead sponsor
Cleveland Dental Institute
Other
Eligibility
20 Years to 60 Years
Enrollment
100 participants
Timeline
2024 – 2025
U.S. locations
1
States / cities
Cleveland, Ohio
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Histomorphometric Analysis Following Sinus Augmentation Using Two Different Bone Graft Materials.

NCT03059914
Conditions
Missing Teeth
Interventions
InterOss, Bio-oss
Device
Lead sponsor
Loma Linda University
Other
Eligibility
18 Years to 103 Years
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Loma Linda, California
Conditions
Edentulous Maxilla
Interventions
ANKYLOS C/X implant A 6.6
Device
Lead sponsor
Dentsply Sirona Implants and Consumables
Industry
Eligibility
18 Years to 80 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2022
U.S. locations
1
States / cities
Fort Lauderdale, Florida
Completed Phase 3 Interventional Accepts healthy volunteers

Evaluate Onset of Action of a Fast Release Aspirin

NCT01420094
Conditions
Healthy Subjects
Interventions
Acetylsalicyclic acid (Fast release Aspirin, BAY1019036), Acetaminophen (Tylenol extra strength), Placebo
Drug
Lead sponsor
Bayer
Industry
Eligibility
16 Years to 45 Years
Enrollment
510 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011
U.S. locations
1
States / cities
Salt Lake City, Utah
Completed Not applicable Interventional Accepts healthy volunteers Results available

Decision Aids for the Management of Suspicious Occlusal Caries Lesions

NCT02340767
Conditions
Dental Caries
Interventions
Spectra Device, DIAGNOdent
Device
Lead sponsor
The National Dental Practice-Based Research Network
Network
Eligibility
6 Years and older
Enrollment
3,085 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
6
States / cities
Birmingham, Alabama • Gainesville, Florida • Minneapolis, Minnesota + 3 more
Conditions
Malocclusion
Interventions
OrthoPulse™
Device
Lead sponsor
Biolux Research Holdings, Inc.
Industry
Eligibility
11 Years to 40 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Suwanee, Georgia
Conditions
Tooth Discoloration
Interventions
ToothWave, powered toothbrush
Device
Lead sponsor
Home Skinovations Ltd.
Industry
Eligibility
18 Years to 70 Years
Enrollment
84 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Fort Wayne, Indiana
Not listed No phase listed Observational Accepts healthy volunteers

EXD-959 Orthodontic Brackets and EXD-961 Related Instruments Trial

NCT03606551
Conditions
Malocclusion
Interventions
EXD-959 Bracket System
Device
Lead sponsor
3M
Industry
Eligibility
11 Years and older
Enrollment
78 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
5
States / cities
Culver City, California • Wellington, Florida • Northfield, Minnesota + 2 more
Conditions
Periodontal Diseases
Interventions
mechanical debridement, adjunctive aPDT, sham aPDT
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Houston, Texas
Conditions
Edentulous Jaw
Interventions
Digital scanning, Photogrammetry
Other
Lead sponsor
William Negreiros
Other
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts