- Conditions
- Knee Osteoarthritis, Primary Total Knee Arthroplasty, Physical Therapy, Pain, Knee Extension
- Interventions
- Ropivacaine, Interspace Between the Popliteal Artery and Capsule of the Knee (iPACK) Block, Saline
- Drug · Procedure
- Lead sponsor
- Duke University
- Other
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 50 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2021
- U.S. locations
- 1
- States / cities
- Durham, North Carolina
Search Results
Search by objective public record fields.
Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results come from ClinicalTrials.gov. When the live registry is unavailable, a clearly labeled stored copy may be shown.
These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Showing 529–552
of 746
matching trials from the live ClinicalTrials.gov search.
- Conditions
- Chronic Knee Pain
- Interventions
- Radiofrequency Ablation, Sham
- Device
- Lead sponsor
- University of Massachusetts, Worcester
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 14 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2026
- U.S. locations
- 1
- States / cities
- Worcester, Massachusetts
- Conditions
- Total Knee Arthroplasty
- Interventions
- Placebo, Duloxetine 60mg
- Drug
- Lead sponsor
- Hospital for Special Surgery, New York
- Other
- Eligibility
- 25 Years to 75 Years
- Enrollment
- 106 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2015
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Total Knee Arthroplasty Postoperative Pain, Opioid Reduction After TKA
- Interventions
- NEUROCUPLE™ Patch, Sham patch, Enhanced Recovery After Surgery (ERAS) Standard of Care
- Device · Other
- Lead sponsor
- Jacques E. Chelly
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 274 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2027
- U.S. locations
- 3
- States / cities
- Pittsburgh, Pennsylvania
- Conditions
- Knee Arthropathy, Allergic Reaction
- Interventions
- TKA with nickel free components, TKA with standard cobalt chromium components
- Device
- Lead sponsor
- Rush University Medical Center
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 9 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2024
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Arthroplasty, Replacement, Knee, Nerve Block
- Interventions
- Adductor Canal Nerve Block Catheter, Adductor Canal Nerve Block Sham Catheter, Bupivacaine
- Device · Drug
- Lead sponsor
- University of Chicago
- Other
- Eligibility
- Up to 85 Years
- Enrollment
- 165 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2014 – 2017
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Total Knee Replacement
- Interventions
- Total knee replacement using Omnibot Knee System, Conventional Total knee replacement, Omnibot Robotic Knee System
- Procedure · Device
- Lead sponsor
- Rothman Institute Orthopaedics
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 60 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2022 – 2023
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- Total Knee Arthroplasty (TKA)
- Interventions
- Cementless Total Knee Arthroplasty, Cemented Total Knee Arthroplasty
- Procedure
- Lead sponsor
- OrthoCarolina Research Institute, Inc.
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 17 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2021
- U.S. locations
- 1
- States / cities
- Charlotte, North Carolina
- Conditions
- Total Knee Anthroplasty
- Interventions
- Total Knee Arthroplasty Medial Parapatellar Approach, Total Knee Arthroplasty Subvastus Approach
- Procedure
- Lead sponsor
- Total Joint Specialists
- Network
- Eligibility
- 18 Years and older
- Enrollment
- 110 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2027
- U.S. locations
- 1
- States / cities
- Sandy Springs, Georgia
- Conditions
- Osteoarthritis, Knee
- Interventions
- Persona Trabecular Metal Tibia, Verasense technology, MUVR
- Device
- Lead sponsor
- Washington Hospital Healthcare System
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 50 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2023
- U.S. locations
- 1
- States / cities
- Fremont, California
- Conditions
- Osteoarthritis, Inflammatory Arthritis
- Interventions
- Platelet Rich Plasma
- Biological
- Lead sponsor
- Exactech
- Industry
- Eligibility
- Not listed
- Enrollment
- 70 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2013
- U.S. locations
- 2
- States / cities
- Lewiston, Maine • Salisbury, Maryland
- Conditions
- Total Knee Replacement
- Interventions
- CPM, GAPFLEX
- Device
- Lead sponsor
- Xeras Medical Technologies
- Industry
- Eligibility
- 50 Years and older
- Enrollment
- 28 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2015 – 2017
- U.S. locations
- 2
- States / cities
- San Antonio, Texas
- Conditions
- Total Knee Replacement, Total Knee Arthroplasty, Pain, Postoperative Pain, Orthopedic Disorder
- Interventions
- SPRINT Beta System
- Device
- Lead sponsor
- SPR Therapeutics, Inc.
- Industry
- Eligibility
- 21 Years to 90 Years
- Enrollment
- 47 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2020
- U.S. locations
- 5
- States / cities
- La Jolla, California • Durham, North Carolina • Cleveland, Ohio + 2 more
- Conditions
- Arthroplasty, Replacement, Knee
- Interventions
- Triathlon® CR Total Knee System
- Device
- Lead sponsor
- Stryker Orthopaedics
- Industry
- Eligibility
- 21 Years to 80 Years
- Enrollment
- 419 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2005 – 2017
- U.S. locations
- 11
- States / cities
- Phoenix, Arizona • Miami, Florida • Columbus, Georgia + 8 more
- Conditions
- Osteoarthritis of the Knee
- Interventions
- t-RFA, C-RFA, Control
- Procedure
- Lead sponsor
- Lyman Medical Research Foundation, Inc.
- Other
- Eligibility
- 40 Years and older
- Enrollment
- 150 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2017 – 2020
- U.S. locations
- 2
- States / cities
- Coeur d'Alene, Idaho • Spokane, Washington
- Conditions
- Osteoarthritis, Postoperative Pain
- Interventions
- pregabalin, Placebo
- Drug
- Lead sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
- Industry
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 307 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2008
- U.S. locations
- 27
- States / cities
- Northport, Alabama • Tuscaloosa, Alabama • Phoenix, Arizona + 21 more
- Conditions
- Knee Osteoarthritis
- Interventions
- SOLUGEL, Placebo
- Dietary Supplement
- Lead sponsor
- University of Arkansas
- Other
- Eligibility
- 50 Years to 75 Years
- Enrollment
- 44 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2026 – 2027
- U.S. locations
- 1
- States / cities
- Little Rock, Arkansas
- Conditions
- Total Knee Arthroplasty
- Interventions
- Methylprednisolone, Placebo
- Drug
- Lead sponsor
- Rush University Medical Center
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 420 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2022 – 2027
- U.S. locations
- 1
- States / cities
- Oak Brook, Illinois
- Conditions
- Pain, Postoperative, Satisfaction
- Interventions
- Ropivacaine
- Drug
- Lead sponsor
- Rothman Institute Orthopaedics
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 164 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2019
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- Total Knee Arthroplasty, Osteoarthritis
- Interventions
- Neuromuscular electrical stimulation, Voluntary exercise
- Procedure
- Lead sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
- NIH
- Eligibility
- 45 Years to 85 Years
- Enrollment
- 200 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- Started 2002
- U.S. locations
- 1
- States / cities
- Newark, Delaware
- Conditions
- Postsurgical Pain
- Interventions
- AYX1 Injection 660 mg / 6 mL, AYX1 Injection 1100 mg / 10 mL, Placebo Injection 6 mL, Placebo Injection 10 mL
- Drug
- Lead sponsor
- Adynxx, Inc.
- Industry
- Eligibility
- 40 Years to 80 Years
- Enrollment
- 120 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2015
- U.S. locations
- 2
- States / cities
- Sheffield, Alabama • Phoenix, Arizona
- Conditions
- Arthroplasty, Replacement, Knee
- Interventions
- CORI™ KNEE TENSIONER
- Device
- Lead sponsor
- Smith & Nephew, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 77 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2025
- U.S. locations
- 4
- States / cities
- New York, New York • New Albany, Ohio • Pittsburgh, Pennsylvania + 1 more
- Conditions
- Osteoarthritis
- Interventions
- Home PT via web-based platform, Home PT via paper manual, outpatient PT
- Other
- Lead sponsor
- Rothman Institute Orthopaedics
- Other
- Eligibility
- 18 Years and older
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- Started 2016
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- Total Knee Arthroplasty, Knee Pain
- Interventions
- 0.1% and 0.4% perineural ropivicaine
- Drug
- Lead sponsor
- University of California, San Diego
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 48 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2011
- U.S. locations
- 1
- States / cities
- Cleveland, Ohio