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Showing 1–19 of 19 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Toxicant Exposure Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Impact of Waterpipe Tobacco Flavors on Waterpipe Smoking Intentions, Perceptions, Patterns, and Toxicant Exposure

NCT03232827
View directory record Official record
Conditions
Smoking, Hookah, Waterpipe Smoking
Interventions
Flavored-Sweetened Waterpipe Tobacco, Unflavored-sweetened waterpipe tobacco, Unflavored-very low sweetened waterpipe tobacco, Flavored-very low sweetened waterpipe
Behavioral
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years to 50 Years
Enrollment
91 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Jun 23, 2019 · Synced Jun 26, 2026, 2:57 PM EDT
Completed No phase listed Observational

Mohawk Culture, Behavior, Toxicant Exposure and Health

NCT00043238
View directory record Official record
Conditions
Thyroid Diseases, Cognition Disorders
Interventions
Not listed
Lead sponsor
National Institute of Environmental Health Sciences (NIEHS)
NIH
Eligibility
17 Years to 18 Years
Enrollment
220 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Ends 2005
U.S. locations
1
States / cities
Hogansburg, New York
Source: ClinicalTrials.gov public record
Updated Apr 13, 2015 · Synced Jun 26, 2026, 2:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effects Among Smokers Who Use and Do Not Use E-Cigarettes

NCT03511001
View directory record Official record
Conditions
Toxicant Exposure
Interventions
E-Cigarette Vs. Smoking as Usual
Other
Lead sponsor
California State University, San Marcos
Other
Eligibility
21 Years and older
Enrollment
187 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
2
States / cities
San Marcos, California • Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Oct 11, 2021 · Synced Jun 26, 2026, 2:57 PM EDT
Recruiting Phase 1Phase 2 Interventional

Examining a Novel Gastrointestinal Intervention to Negate Environmental Toxicants (ENGINE)

NCT07226440
View directory record Official record
Conditions
Toxicant Exposure, Firefighter, Occupational Exposure to Chemicals
Interventions
Colesevelam, Placebo
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older · Male only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Apr 23, 2026 · Synced Jun 26, 2026, 2:57 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Determining Levels of [D10] Phenanthrene Tetraol in Smokers' Urine

NCT01092650
View directory record Official record
Conditions
Tobacco Toxicant Exposure
Interventions
Deuterated phenanthrene
Drug
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2011
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 26, 2014 · Synced Jun 26, 2026, 2:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Potential Effects of Electronic Nicotine Delivery System Flavor Regulations on African American Menthol Smokers

NCT05023096
View directory record Official record
Conditions
Electronic Nicotine Delivery System Flavors
Interventions
Tobacco product administration and assessment
Other
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
21 Years and older
Enrollment
71 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 21, 2026 · Synced Jun 26, 2026, 2:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Concurrent Hookah and Alcohol Consumption on Smoking Topography and Toxicant Exposure

NCT03096860
View directory record Official record
Conditions
Alcohol Use, Unspecified, Hookah Smoking
Interventions
Active alcohol consumption, Placebo consumption
Other
Lead sponsor
Oklahoma State University
Other
Eligibility
21 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Oct 12, 2017 · Synced Jun 26, 2026, 2:57 PM EDT
Terminated Phase 1 Interventional Accepts healthy volunteers

Metabolism of Deuterated NNN in Smokeless Tobacco Users

NCT02414477
View directory record Official record
Conditions
Tobacco Toxicant Exposure
Interventions
Deuterated NNN
Drug
Lead sponsor
University of Minnesota
Other
Eligibility
21 Years to 70 Years
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 29, 2025 · Synced Jun 26, 2026, 2:57 PM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Novel Determinants and Measures of Smokeless Tobacco Use: Study 1

NCT01067586
View directory record Official record
Conditions
Smokeless Tobacco Use, Tobacco Dependence
Interventions
Not listed
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
359 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2013
U.S. locations
3
States / cities
Minneapolis, Minnesota • Eugene, Oregon • Morgantown, West Virginia
Source: ClinicalTrials.gov public record
Updated Dec 21, 2022 · Synced Jun 26, 2026, 2:57 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Observational Study of Exposure to Environmental Toxicants Among Firefighters

NCT05643014
View directory record Official record
Conditions
Healthy
Interventions
Sample collection
Other
Lead sponsor
Masonic Cancer Center, University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2027
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 11, 2026 · Synced Jun 26, 2026, 2:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effect of Waterpipe Size on Smoking Behavior and Exposures

NCT05705375
View directory record Official record
Conditions
Waterpipe Size
Interventions
Waterpipe size
Other
Lead sponsor
The University of Texas at Arlington
Other
Eligibility
21 Years to 39 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Arlington, Texas
Source: ClinicalTrials.gov public record
Updated Nov 4, 2025 · Synced Jun 26, 2026, 2:57 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Epigenetic and Developmental Effects of In Utero Exposure to Environmental Toxicants

NCT01815385
View directory record Official record
Conditions
Full Term Infants, Environmental Exposures, Adiposity
Interventions
Not listed
Lead sponsor
Montefiore Medical Center
Other
Eligibility
1 Hour to 72 Hours
Enrollment
110 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2020
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Feb 10, 2021 · Synced Jun 26, 2026, 2:57 PM EDT
Not yet recruiting Phase 2 Interventional

Mitigating Toxic Impact: The Role of Coenzyme Q10 in Post-Exposure Protection

NCT06962657
View directory record Official record
Conditions
Toxicant Induced Chronic Multisymptom Illness and Associated Symptoms and Comorbidities
Interventions
Ubiquinone 100 mg Oral Soft Gel, Placebo
Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Jun 26, 2026, 2:57 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Carcinogen and Toxicant Exposure Among Young Adults Who Co-Use E-cigarettes and Cannabis (Co-Tox Study)

NCT07167225
View directory record Official record
Conditions
Cigarette Smoking-Related Carcinoma, E-Cig Use
Interventions
Effectiveness of different recruitment approaches, Choice of study completion locations, Cannabis Engagement Assessment, E-cigarette dependence Scale
Other
Lead sponsor
Roswell Park Cancer Institute
Other
Eligibility
18 Years to 25 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated May 7, 2026 · Synced Jun 26, 2026, 2:57 PM EDT
Completed Phase 1 Interventional

Concurrent vs. Sequential Cessation of Dual Cigarette and E-cigarette Use

NCT06027840
View directory record Official record
Conditions
Cigarette Smoking, E-Cigarette Use, Smoking Cessation
Interventions
Varenicline, Counseling, Guided Self-Change Booklets
Drug · Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jun 7, 2026 · Synced Jun 26, 2026, 2:57 PM EDT
Suspended Not applicable Interventional Accepts healthy volunteers

Environmental Toxicants Avoidance Study

NCT04821752
View directory record Official record
Conditions
Pollution; Exposure, Glucose Intolerance, Glycemic Control
Interventions
Avoidance Education
Behavioral
Lead sponsor
Bastyr University
Other
Eligibility
18 Years to 100 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Kenmore, Washington
Source: ClinicalTrials.gov public record
Updated Sep 26, 2024 · Synced Jun 26, 2026, 2:57 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Effect of Menthol on ENDS Users' Addiction and Exposure

NCT05338801
View directory record Official record
Conditions
Electronic Cigarette Use
Interventions
Menthol-flavored e-cigarette, Tobacco-flavored e-cigarette
Other
Lead sponsor
Florida International University
Other
Eligibility
21 Years to 35 Years
Enrollment
250 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Mar 31, 2026 · Synced Jun 26, 2026, 2:57 PM EDT
Recruiting Not applicable Interventional

Cigarette Filter Study

NCT07348679
View directory record Official record
Conditions
Smoking ( Cigarette)
Interventions
Charcoal filtered cigarettes with marketing, Charcoal filtered cigarette without marketing, Non-charcoal filtered cigarettes
Behavioral
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
21 Years and older
Enrollment
252 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
New Brunswick, New Jersey
Source: ClinicalTrials.gov public record
Updated Jun 4, 2026 · Synced Jun 26, 2026, 2:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Hookah Additive Research to Inform Product Standards

NCT05453773
View directory record Official record
Conditions
Tobacco-Related Carcinoma
Interventions
Questionnaire Administration, Tobacco Smoking
Other · Behavioral
Lead sponsor
Ohio State University Comprehensive Cancer Center
Other
Eligibility
21 Years to 50 Years
Enrollment
54 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 30, 2024 · Synced Jun 26, 2026, 2:57 PM EDT