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Showing 1–24 of 1,579 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Trauma-related PTSD Clear all
Completed Not applicable Interventional

Telephone Care as a Substitute for Routine Psychiatric Medication

NCT00105885
View directory record Official record
Conditions
Major Depression, Posttraumatic Stress Disorders, Anxiety Disorders
Interventions
telephone care
Procedure
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years and older
Enrollment
324 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2008
U.S. locations
1
States / cities
White River Junction, Vermont
Source: ClinicalTrials.gov public record
Updated Feb 9, 2014 · Synced Jun 26, 2026, 2:45 PM EDT
Completed Phase 4 Interventional Results available

Dopamine Enhancement of Fear Extinction Learning in PTSD (1R21MH108753)

NCT02560389
View directory record Official record
Conditions
Stress Disorder, Post Traumatic
Interventions
Placebo, Levodopa
Drug
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
25 Years to 50 Years · Female only
Enrollment
103 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Jun 24, 2019 · Synced Jun 26, 2026, 2:45 PM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Stress, Adjustment And Growth In Children With Cancer And Their Parents

NCT01044160
View directory record Official record
Conditions
Posttraumatic Growth, Posttraumatic Stress Disorder
Interventions
Not listed
Lead sponsor
St. Jude Children's Research Hospital
Other
Eligibility
3 Years to 25 Years
Enrollment
663 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2026
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Jun 16, 2026 · Synced Jun 26, 2026, 2:45 PM EDT
Recruiting Not applicable Interventional

Adaptation and Examination of a Trauma-informed Intervention for Pregnant Veterans

NCT06906185
View directory record Official record
Conditions
Trauma-related Mental Health Symptoms
Interventions
Calm Moms-V, Care As Usual
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
Female only
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Jun 26, 2026, 2:45 PM EDT
Completed Phase 3 Interventional Results available

Prazosin for Treatment of Patients With Alcohol Dependence (AD) and Post Traumatic Stress Disorder (PTSD).

NCT00744055
View directory record Official record
Conditions
Alcohol Dependence, Stress Disorders, Post-Traumatic
Interventions
Prazosin, Placebo
Drug
Lead sponsor
Yale University
Other
Eligibility
21 Years to 65 Years
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
1
States / cities
West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 18, 2020 · Synced Jun 26, 2026, 2:45 PM EDT
Completed Not applicable Interventional

Effect of Repetitive Transcranial Direct Current Stimulation (tDCS) on Chronic Pelvic Pain

NCT00554320
View directory record Official record
Conditions
Chronic Pelvic Pain, Interstitial Cystitis, Post Traumatic Stress Disorder, Fibromyalgia, Irritable Bowel Syndrome
Interventions
tDCS
Procedure
Lead sponsor
Summa Health System
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009
U.S. locations
1
States / cities
Akron, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 17, 2009 · Synced Jun 26, 2026, 2:45 PM EDT
Not listed Not applicable Interventional

Delivery of Self Training and Education for Stressful Situations-Telephone Version

NCT01502449
View directory record Official record
Conditions
PTSD
Interventions
DESTRESS-T, Optimized Usual Care (OUC)
Behavioral · Other
Lead sponsor
Uniformed Services University of the Health Sciences
Federal
Eligibility
18 Years to 65 Years
Enrollment
91 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Columbus, Georgia
Source: ClinicalTrials.gov public record
Updated Jan 11, 2012 · Synced Jun 26, 2026, 2:45 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

NightWare and Cardiovascular Health in Adults With PTSD

NCT05365607
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Cardiovascular Diseases, Autonomic Dysfunction, Vascular Stiffness, Nightmare, Endothelial Dysfunction
Interventions
NightWare, Sham NightWare
Device
Lead sponsor
University of Colorado, Denver
Other
Eligibility
22 Years to 99 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
2
States / cities
Aurora, Colorado • Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Oct 7, 2024 · Synced Jun 26, 2026, 2:45 PM EDT
Recruiting Early Phase 1 Interventional

Responsive Neurostimulation for Post-Traumatic Stress Disorder

NCT04152993
View directory record Official record
Conditions
Post-Traumatic Stress Disorder
Interventions
NeuroPace® RNS® System
Device
Lead sponsor
VA Greater Los Angeles Healthcare System
Federal
Eligibility
25 Years to 60 Years · Male only
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated May 27, 2024 · Synced Jun 26, 2026, 2:45 PM EDT
Completed Not applicable Interventional

Mindfulness and Present Centered Therapies for PTSD: Efficacy and Mechanisms

NCT01347749
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Mindfulness & Compassion Meditation-based Exposure Therapy, Present Centered Therapy for PTSD
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
21 Years to 50 Years · Male only
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
2
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Nov 5, 2019 · Synced Jun 26, 2026, 2:45 PM EDT
Terminated Phase 3 Interventional Results available

Combined Treatment of Prolonged Exposure and Pramipexole for Posttraumatic Stress Disorder and Depression

NCT03765138
View directory record Official record
Conditions
PTSD, MDD
Interventions
PE/Pramipexole
Combination Product
Lead sponsor
Research Foundation for Mental Hygiene, Inc.
Other
Eligibility
18 Years to 60 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 25, 2019 · Synced Jun 26, 2026, 2:45 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Feasibility and ML Training Investigation of the Senseye DT for Diagnosis of Adults with PTSD

NCT05717439
View directory record Official record
Conditions
PTSD, Generalized Anxiety Disorder, Major Depressive Disorder
Interventions
CAPS-5-R, Senseye DT
Diagnostic Test
Lead sponsor
Senseye, Inc.
Industry
Eligibility
18 Years and older
Enrollment
338 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
5
States / cities
Aurora, Colorado • Meridian, Idaho • Charleston, South Carolina + 2 more
Source: ClinicalTrials.gov public record
Updated Dec 10, 2024 · Synced Jun 26, 2026, 2:45 PM EDT
Withdrawn No phase listed Observational

Characterization of the Use of Antipsychotics in Posttraumatic Stress Disorder During the Past Decade

NCT00233467
View directory record Official record
Conditions
PTSD, Posttraumatic Stress Disorder
Interventions
Not listed
Lead sponsor
Tuscaloosa Research & Education Advancement Corporation
Other
Eligibility
19 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005
U.S. locations
1
States / cities
Tuscaloosa, Alabama
Source: ClinicalTrials.gov public record
Updated Sep 13, 2017 · Synced Jun 26, 2026, 2:45 PM EDT
Not yet recruiting Not applicable Interventional

Comparative Effectiveness of SPARCS and Unified Protocol for Youth With Chronic Medical Conditions and Trauma-Related Distress

NCT07483333
View directory record Official record
Conditions
Trauma Exposure, Trauma, Trauma and Stressor Related Disorder, Mental Health Functioning, Chronic Medical Conditions, Chronic Medical Condition, Chronic Medical Illness, Posttraumatic Stress Disorder PTSD, Posttraumatic Stress Disorders, Posttraumatic Stress Symptoms, Posttraumatic Stress
Interventions
Structured Psychotherapy for Adolescents Responding to Chronic Stress - Group, Unified Protocol for Transdiagnostic Treatment of Emotional Disorders in Children and Adolescents - Group, Unified Protocol for Transdiagnostic Treatment of Emotional Disorders in Children and Adolescents - Individual, Structured Psychotherapy for Adolescents Responding to Chronic Stress - Individual
Behavioral
Lead sponsor
Anthony Vesco
Other
Eligibility
8 Years to 18 Years
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 18, 2026 · Synced Jun 26, 2026, 2:45 PM EDT
Active, not recruiting Not applicable Interventional

CBT vs. Supportive Texts for PTSD & Hazardous Drinking (Project Better Study 2)

NCT06648395
View directory record Official record
Conditions
Alcohol Use, Posttraumatic Stress Disorder
Interventions
CBT Text Messages, Supportive Messages
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
333 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 7, 2025 · Synced Jun 26, 2026, 2:45 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

The Effects of Very Brief Exposure on PTSD in U.S. Combat Veterans

NCT06218381
View directory record Official record
Conditions
Post Traumatic Stress Disorder
Interventions
Very Brief Exposure to Combat Images
Other
Lead sponsor
Children's Hospital Los Angeles
Other
Eligibility
18 Years to 50 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Dec 17, 2025 · Synced Jun 26, 2026, 2:45 PM EDT
Completed Not applicable Interventional

A Pilot Exercise Study for PTSD in Women Veterans

NCT01892033
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Aerobic Exercise
Behavioral
Lead sponsor
North Texas Veterans Healthcare System
Federal
Eligibility
18 Years to 50 Years · Female only
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Apr 25, 2019 · Synced Jun 26, 2026, 2:45 PM EDT
Completed Phase 4 Interventional

Trial of Seroquel SR for Alcohol Dependence and Comorbid Anxiety

NCT00352469
View directory record Official record
Conditions
Alcoholism, Anxiety Disorders, Generalized Anxiety Disorder, Post-Traumatic Stress Disorder, Panic Disorder, Obsessive-Compulsive Disorder
Interventions
Seroquel XR
Drug
Lead sponsor
Creighton University
Other
Eligibility
19 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Dec 7, 2008 · Synced Jun 26, 2026, 2:45 PM EDT
Completed Not applicable Interventional Results available

Cognitive-Behavior Therapy for Posttraumatic Headache

NCT02419131
View directory record Official record
Conditions
Post-traumatic Headache, PTSD
Interventions
Behavioral Headache Therapy, Cognitive Processing Therapy, Treatment as Usual
Behavioral
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years to 70 Years
Enrollment
193 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Aug 12, 2024 · Synced Jun 26, 2026, 2:45 PM EDT
Completed Not applicable Interventional

Telemedicine for Improved Delivery of Psychosocial Treatments for Post Traumatic Stress Disorder

NCT01158001
View directory record Official record
Conditions
Posttraumatic Stress Disorders, Depression, Anxiety
Interventions
Prolonged exposure therapy
Behavioral
Lead sponsor
Veterans Medical Research Foundation
Other
Eligibility
18 Years and older
Enrollment
211 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jun 23, 2015 · Synced Jun 26, 2026, 2:45 PM EDT
Recruiting Not applicable Interventional

Family Involvement in Treatment for PTSD (FIT-PTSD): A Brief, Feasible Method for Enhancing Outcomes, Retention, and Engagement

NCT05267665
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Brief Family Intervention (BFI)
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
3
States / cities
Boston, Massachusetts • Durham, North Carolina • Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 19, 2026 · Synced Jun 26, 2026, 2:45 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Deployment Health in Regular Military Women

NCT01692067
View directory record Official record
Conditions
Military Physical and Sexual Trauma, Combat Trauma, PTSD, TBI
Interventions
Not listed
Lead sponsor
Iowa City Veterans Affairs Medical Center
Federal
Eligibility
18 Years to 60 Years
Enrollment
871 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2013
U.S. locations
2
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jul 18, 2019 · Synced Jun 26, 2026, 2:45 PM EDT
Completed No phase listed Observational

Treatment for the Mental Health Impact of Killing in War

NCT01406834
View directory record Official record
Conditions
Posttraumatic Stress Disorder (PTSD)
Interventions
Impact of Killing CBT Treatment
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 70 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Aug 17, 2014 · Synced Jun 26, 2026, 2:45 PM EDT
Completed Not applicable Interventional Results available

Behavioral Activation for PTSD/Depression Treatment in OIF/OEF Veterans

NCT00805532
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Depression
Interventions
Behavioral Activation treatment, Treatment as Usual
Behavioral · Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
2
States / cities
Portland, Oregon • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Nov 4, 2018 · Synced Jun 26, 2026, 2:45 PM EDT