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ClinicalTrials.gov public records Last synced Nov 10, 2026, 12:29 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 1,621 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Trauma-related PTSD Clear all

Conditions: PTSD
Interventions: Therapist Guided Prolonged Exposure with BioWare Device, Record Only Prolonged Exposure with BioWare Device; Device
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 18 Years to 75 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Stress Disorders, Post-Traumatic, Bulimia Nervosa
Interventions: Prazosin, Placebo; Drug
Lead sponsor: Milton S. Hershey Medical Center; Other
Eligibility: 18 Years to 45 Years · Female only
Enrollment: 9 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2018
U.S. locations: 1
States / cities: Hershey, Pennsylvania

Conditions: PTSD, Substance Addiction
Interventions: Prolonged Exposure, Motivational Enhancement Therapy; Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years to 65 Years
Enrollment: 183 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2016
U.S. locations: 2
States / cities: Minneapolis, Minnesota • Philadelphia, Pennsylvania

Conditions: Intimate Partner Violence
Interventions: Strength at Home (SAH), Treatment as usual for IPV; Behavioral
Lead sponsor: Boston University; Other
Eligibility: 18 Years and older
Enrollment: 800 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Posttraumatic Stress Disorder, Major Depressive Disorder
Interventions: Positive Processes and Transition to Health, Progressive Muscle Relaxation; Behavioral
Lead sponsor: Case Western Reserve University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 135 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2027
U.S. locations: 3
States / cities: Newark, Delaware • Cleveland, Ohio • Seattle, Washington

Conditions: Post Traumatic Stress Disorder PTSD
Interventions: Prolonged Exposure Therapy, Cognitive Processing Therapy, Written Exposure Therapy, Shared Decision Making (SHARE); Behavioral · Other
Lead sponsor: The University of Texas Health Science Center at San Antonio; Other
Eligibility: 18 Years and older
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 2
States / cities: Fort Hood, Texas • San Antonio, Texas

Conditions: Post-traumatic Stress Disorder (PTSD), Trauma
Interventions: Positron emission tomography (PET) imaging; Other
Lead sponsor: NYU Langone Health; Other
Eligibility: 18 Years to 55 Years
Enrollment: 17 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2016
U.S. locations: 1
States / cities: New York, New York

Conditions: Psychological Distress, Depression, Anxiety, Post-traumatic Stress Disorder, Informal Caregivers, Family Members
Interventions: mobile mindfulness, standard mindfulness, education; Behavioral
Lead sponsor: Duke University; Other
Eligibility: 18 Years and older
Enrollment: 90 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2017
U.S. locations: 2
States / cities: Durham, North Carolina • Seattle, Washington

Conditions: Posttraumatic Stress Disorder (PTSD)
Interventions: Web-based Think/No-Think retrieval-suppression training; Behavioral
Lead sponsor: Palo Alto Veterans Institute for Research; Other
Eligibility: 18 Years and older
Enrollment: 11 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Palo Alto, California

Conditions: Posttraumatic Stress Disorder, Depression, Alcohol-Related Disorders, Suicidal Ideation, Substance-Related Disorders, Mild Cognitive Impairment, Quality of Life, Pain, Wounds and Injury, Brain Injuries, Chronic Disease
Interventions: Motivational Interviewing, Cognitive Behavioral Therapy Elements, Care Management, Fluoxetine, Fluvoxamine, Paroxetine, Sertraline, Citalopram, Venlafaxine, Duloxetine, Mirtazapine, Diphenhydramine, Trazodone, Prazosin; Behavioral · Drug
Lead sponsor: University of Washington; Other
Eligibility: 18 Years and older
Enrollment: 635 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2019
U.S. locations: 24
States / cities: Scottsdale, Arizona • Beverly Hills, California • Sacramento, California + 20 more

Conditions: Posttraumatic Stress Disorder
Interventions: imaginal therapy, exercise, self-care; Behavioral
Lead sponsor: The University of Texas Health Science Center at San Antonio; Other
Eligibility: 18 Years and older
Enrollment: 72 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2017
U.S. locations: 1
States / cities: Fort Hood, Texas

Conditions: HIV, Depression, Posttraumatic Stress Disorder
Interventions: Enhanced Sexual Health Intervention for Men (ES-HIM), Health Promotion (HP) Comparison Arm; Behavioral
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 18 Years and older · Male only
Enrollment: 118 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2011
U.S. locations: 4
States / cities: Inglewood, California • Los Angeles, California

Conditions: Posttraumatic Stress Disorders
Interventions: Cognitive Behavioral Therapy For Work Success (CBTw), Psychoeducation; Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years and older
Enrollment: 294 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2024
U.S. locations: 3
States / cities: Hines, Illinois • Indianapolis, Indiana • St Louis, Missouri

Conditions: Alcohol Dependence, Post-Traumatic Stress Disorder (PTSD)
Interventions: Enhanced-Cognitive Processing Therapy-C (E-CPT-C), Zonisamide, Placebo; Behavioral · Drug
Lead sponsor: Yale University; Other
Eligibility: 21 Years to 65 Years
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2019
U.S. locations: 1
States / cities: West Haven, Connecticut

Conditions: PTSD
Interventions: Cognitive Processing Therapy - Cognitive; Behavioral
Lead sponsor: Duke University; Other
Eligibility: 40 Years to 65 Years
Enrollment: 112 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2021
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Orthopedic Trauma Surgery Patients, Postoperative Pain, Opioid Use, Depression, Post-traumatic Stress Disorder (PTSD)
Interventions: Ketamine, standard general anesthesia; Drug
Lead sponsor: Texas Tech University Health Sciences Center; Other
Eligibility: 18 Years to 65 Years
Enrollment: 90 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 2
States / cities: Lubbock, Texas

Conditions: Military Sexual Trauma (MST), Post Traumatic Stress Disorder
Interventions: Health & Wellness, Warrior Renew; Behavioral
Lead sponsor: Seattle Institute for Biomedical and Clinical Research; Other
Eligibility: 18 Years to 75 Years
Enrollment: 191 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 2
States / cities: Portland, Oregon • Seattle, Washington

Conditions: Well-Being, Psychological, Dissociation, Maternal Care Patterns, Maternal Behavior, Maternal Distress, Mood Disturbance, Emotional Regulation, Post Traumatic Stress Disorder
Interventions: Neuroptimal (Zengar, Inc.) Neurofeedback; Device
Lead sponsor: Wayne State University; Other
Eligibility: 18 Years to 60 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Detroit, Michigan

Conditions: Stress Disorders, Post-Traumatic, Anxiety Disorders, Mental Disorder, Traumatic Disorder
Interventions: Prolonged Exposure; Behavioral
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 18 Years and older
Enrollment: 109 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2023
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Post-Traumatic Stress Disorder
Interventions: Online Cognitive-Behavioral Therapy, Online Supportive Therapy; Behavioral
Lead sponsor: Icahn School of Medicine at Mount Sinai; Other
Eligibility: 18 Years and older
Enrollment: 105 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2021
U.S. locations: 4
States / cities: New Haven, Connecticut • Boston, Massachusetts • New York, New York + 1 more

Conditions: Post Traumatic Stress Disorder (PTSD)
Interventions: Stellate Ganglion Block injection with ropivicane, Placebo Procedure; Procedure
Lead sponsor: United States Naval Medical Center, San Diego; Federal
Eligibility: 18 Years and older
Enrollment: 41 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2016
U.S. locations: 1
States / cities: San Diego, California

Conditions: Stress Disorders, Post-Traumatic
Interventions: Intensive Treatment, Treatment as Usual; Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years and older
Enrollment: 23 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2016
U.S. locations: 2
States / cities: West Haven, Connecticut • Boston, Massachusetts

Conditions: Post Traumatic Stress Disorder
Interventions: Prolonged Exposure for Primary Care (PE-PC), EAP Treatment as Usual (TAU); Behavioral
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years and older
Enrollment: 410 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2027
U.S. locations: 14
States / cities: San Diego, California • Carrollton, Georgia • Ann Arbor, Michigan + 9 more

Conditions: Traumatic Brain Injury, Posttraumatic Stress Disorder
Interventions: LED, sham LED; Other
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 21 Years to 55 Years
Enrollment: 8 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2025
U.S. locations: 1
States / cities: Boston, Massachusetts

Search by objective public record fields.

Clinical Trial Intelligent Biometrics for PTSD - Clinical Trial

Effectiveness of Prazosin in Bulimic Patients Experiencing Nightmares Due to PTSD

Integrated vs Sequential Treatment for PTSD and Addiction

Evaluating Interventions for Intimate Partner Violence Use in Washington State

Positive Processes and Transition to Health (PATH)

Shared Decision Making in PTSD Treatment

Kappa Opioid Receptor Imaging in Post-traumatic Stress Disorder (PTSD)

Mobile Mindfulness to Improve Psychological Distress After Critical Illness

Trauma Suppression Training for Veterans

A Policy Relevant US Trauma Care System Pragmatic Trial for PTSD and Comorbidity

The Role of Exercise in the Treatment of PTSD Symptoms

An HIV Intervention for Black Men at Risk - The Enhanced Sexual Health Intervention for Men (ES-HIM)

Cognitive Behavioral Therapy to Improve Work and Wellness in Veterans With Mental Illness

Zonisamide in Addition to E-CPT-C for Veterans With PTSD and Comorbid Alcohol Dependence

The Effect of Reducing Posttraumatic Stress Disorder Symptoms on Cardiovascular Risk

Ketamine for Pain, Opioid Use, and Mental Health in Orthopedic Trauma Patients

Efficacy of Virtual Warrior Renew Therapy for Veterans Who Experienced Military Sexual Trauma

An Adjunctive Neurofeedback Training Program to Enhance Wellness Among Trauma-Exposed Postpartum Mothers

Peer Social Support During In Vivo Exposure for PTSD

Online Therapy for Posttraumatic Stress Symptoms in WTC Responders and Survivors

A Randomized, Placebo-Controlled Trial of Stellate Ganglion Block in the Treatment of Post Traumatic Stress Disorder

Intensive Treatment for Chronic Pain and Posttraumatic Stress Disorder (PTSD)

Reducing Posttraumatic Stress Disorder (PTSD) Symptoms in First Responders and Frontline Health Care Workers

LED Treatment to Improve Cognition and Promote Recovery in TBI