Independent directory Public ClinicalTrials.gov records United States
Clinical Trials Finder
Objective public record navigation
Search Results

Search by objective public record fields.

Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results are retrieved from ClinicalTrials.gov and synchronized into the directory. Search pages remain noindex by default.

Clear filters
ClinicalTrials.gov public records Last synced Sep 7, 2026, 5:27 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 146 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Condition: Tremor Essential Clear all
Completed Phase 2 Interventional Results available

Multiple-dose,Double-blind,Placebo-controlled Study of Sodium Oxybate in Patients With Essential Tremor

NCT00598078
View directory record Official record
Conditions
Essential Tremor
Interventions
Sodium Oxybate, Placebo
Drug · Other
Lead sponsor
Jazz Pharmaceuticals
Industry
Eligibility
50 Years to 75 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Bingham Farms, Michigan
Source: ClinicalTrials.gov public record
Updated Jan 22, 2012 · Synced Sep 7, 2026, 5:27 PM EDT
Completed Phase 1 Interventional

1-Octanol to Treat Essential Tremor

NCT00016679
View directory record Official record
Conditions
Essential Tremor
Interventions
1-Octanol
Drug
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
Not listed
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2004
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 3, 2008 · Synced Sep 7, 2026, 5:27 PM EDT
Completed No phase listed Observational

Adaptive Portable Essential Tremor Monitor

NCT01602042
View directory record Official record
Conditions
Essential Tremor
Interventions
Not listed
Lead sponsor
Great Lakes NeuroTechnologies Inc.
Industry
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012
U.S. locations
2
States / cities
Chicago, Illinois • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Dec 3, 2012 · Synced Sep 7, 2026, 5:27 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Functional Neuroimaging Feedback for Focused Ultrasound Thalamotomy

NCT03560622
View directory record Official record
Conditions
Essential Tremor
Interventions
multi-modality neuroimaging
Device
Lead sponsor
Vibhor Krishna
Other
Eligibility
40 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 23, 2021 · Synced Sep 7, 2026, 5:27 PM EDT
Active, not recruiting Not applicable Interventional

Bilateral Treatment of Medication Refractory Essential Tremor

NCT04112381
View directory record Official record
Conditions
Essential Tremor
Interventions
Exablate Model 4000 Type 1.0/1.1
Device
Lead sponsor
InSightec
Industry
Eligibility
22 Years and older
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
7
States / cities
Stanford, California • Baltimore, Maryland • New York, New York + 4 more
Source: ClinicalTrials.gov public record
Updated Apr 30, 2025 · Synced Sep 7, 2026, 5:27 PM EDT
Recruiting Not applicable Interventional

Circadian Adaptive DBS in Essential Tremor

NCT06635811
View directory record Official record
Conditions
Essential Tremor, Essential Tremor (ET), Essential Tremor, Movement Disorders
Interventions
Circadian Adaptive DBS, Conventional DBS
Device
Lead sponsor
University of Florida
Other
Eligibility
21 Years to 89 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jul 29, 2026 · Synced Sep 7, 2026, 5:27 PM EDT
Not listed Not applicable Interventional

Gamma Knife Radiosurgery for Treatment of Essential Tremor

NCT02255929
View directory record Official record
Conditions
Essential Tremor
Interventions
Gamma Knife Radiosurgery
Radiation
Lead sponsor
Swedish Medical Center
Other
Eligibility
18 Years and older
Enrollment
183 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2023
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jan 22, 2023 · Synced Sep 7, 2026, 5:27 PM EDT
Completed Phase 4 Interventional Results available

Propranolol and Botulinum Toxin for Essential Vocal Tremor

NCT02111369
View directory record Official record
Conditions
Essential Vocal Tremor, Essential Voice Tremor, Essential Tremor, Voice Tremor, Vocal Tremor
Interventions
Propranolol, Botulinum Toxin
Drug · Procedure
Lead sponsor
Emory University
Other
Eligibility
45 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Apr 26, 2016 · Synced Sep 7, 2026, 5:27 PM EDT
Completed Phase 4 Interventional

Pregabalin (Lyrica) for the Treatment of Essential Tremor

NCT00584376
View directory record Official record
Conditions
Essential Tremor
Interventions
Pregabalin, Placebo
Drug
Lead sponsor
University of South Florida
Other
Eligibility
18 Years to 80 Years
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
8
States / cities
Birmingham, Alabama • Tampa, Florida • Atlanta, Georgia + 5 more
Source: ClinicalTrials.gov public record
Updated Jun 17, 2012 · Synced Sep 7, 2026, 5:27 PM EDT
Completed Phase 1Phase 2 Interventional Results available

Double-Blind, Placebo Controlled Pilot Study of Octanoic Acid in Essential Tremor

NCT00848172
View directory record Official record
Conditions
Essential Tremor
Interventions
Octanoic Acid, Placebo
Drug
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
21 Years and older
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 26, 2012 · Synced Sep 7, 2026, 5:27 PM EDT
Completed Phase 2 Interventional Results available

Clinical Trial Characterizing the Bioavailability of 1-Octanol in Adults With Ethanol-responsive Essential Tremor

NCT00102596
View directory record Official record
Conditions
Essential Tremor
Interventions
1-Octanol
Drug
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
21 Years and older
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 31, 2012 · Synced Sep 7, 2026, 5:27 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Sensory Gating Measured With Microelectrode Recording (MER) During Deep Brain Stimulation (DBS) Surgery

NCT02320266
View directory record Official record
Conditions
Parkinson's Disease, Essential Tremor, Dystonia, Obsessive Compulsive Disorder
Interventions
Not listed
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 80 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2025
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated May 12, 2024 · Synced Sep 7, 2026, 5:27 PM EDT
Completed Phase 2 Interventional Results available

A Clinical Trial of PRAX-944 in Participants With Essential Tremor

NCT05021978
View directory record Official record
Conditions
Essential Tremor
Interventions
Part A: 20 and 40 mg PRAX-944, Part B: 120 mg PRAX-944, Part B: 120 mg PRAX-944 and Placebo
Drug
Lead sponsor
Praxis Precision Medicines
Industry
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
2
States / cities
Port Charlotte, Florida • Spokane, Washington
Source: ClinicalTrials.gov public record
Updated Feb 29, 2024 · Synced Sep 7, 2026, 5:27 PM EDT
Completed Not applicable Interventional

Symptomatic Relief of Action Tremor With Cala Trio Using Trio+ Bands

NCT05480215
View directory record Official record
Conditions
Essential Tremor, Parkinson Disease
Interventions
Cala Device
Device
Lead sponsor
Cala Health, Inc.
Industry
Eligibility
22 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
San Mateo, California
Source: ClinicalTrials.gov public record
Updated Jul 28, 2022 · Synced Sep 7, 2026, 5:27 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Analysis and Suppression of Tremor During Grasp Using Ultrasound Imaging and Electrical Stimulation

NCT05308368
View directory record Official record
Conditions
Parkinson Disease, Essential Tremor
Interventions
Ultrasound Imaging, Electromyography, Inertial Measurement Units (IMU), Functional Electrical Stimulation (FES)
Device
Lead sponsor
North Carolina State University
Other
Eligibility
18 Years to 90 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Raleigh, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 26, 2025 · Synced Sep 7, 2026, 5:27 PM EDT
Completed Phase 1 Interventional

Octanoic Acid for Essential Tremor

NCT01468948
View directory record Official record
Conditions
Essential Tremor
Interventions
Octanoic Acid
Drug
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
21 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 15, 2019 · Synced Sep 7, 2026, 5:27 PM EDT
Completed Not applicable Interventional

Upper Limb Tremor Reduction in Essential Tremor Patients

NCT06343285
View directory record Official record
Conditions
Essential Tremor
Interventions
Encora Therapeutics Tremor Reduction Device
Device
Lead sponsor
Encora, Inc.
Industry
Eligibility
22 Years to 80 Years
Enrollment
71 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 30, 2025 · Synced Sep 7, 2026, 5:27 PM EDT
Not listed Phase 2 Interventional Accepts healthy volunteers

An Efficacy/Safety Study of Perampanel for Reducing Essential Tremor

NCT02668146
View directory record Official record
Conditions
Essential Tremor
Interventions
Perampanel, Placebo
Drug
Lead sponsor
VA Greater Los Angeles Healthcare System
Federal
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Sep 11, 2016 · Synced Sep 7, 2026, 5:27 PM EDT
Completed No phase listed Observational Results available

A Post-Market Study Evaluating the Safety of Infinity DBS System With MR Conditional Labeling

NCT03884231
View directory record Official record
Conditions
Movement Disorders, Parkinson Disease, Essential Tremor, Tremor, Dystonia
Interventions
Infinity DBS System with MR Conditional labelling
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
Not listed
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
9
States / cities
Tucson, Arizona • Aurora, Colorado • Littleton, Colorado + 6 more
Source: ClinicalTrials.gov public record
Updated Nov 19, 2024 · Synced Sep 7, 2026, 5:27 PM EDT
Completed Not applicable Interventional

Continuous Tremor Assessment During Daily Activities

NCT01978080
View directory record Official record
Conditions
Essential Tremor
Interventions
Kinesia HomeView
Device
Lead sponsor
Great Lakes NeuroTechnologies Inc.
Industry
Eligibility
Not listed
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2013
U.S. locations
2
States / cities
Chicago, Illinois • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Dec 9, 2014 · Synced Sep 7, 2026, 5:27 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Dual Lead Thalamic Deep Brain Recording (DBR)-DBS Interface for Closed Loop Control of Severe Essential Tremor

NCT04212780
View directory record Official record
Conditions
Essential Tremor
Interventions
Medtronic Summit Rechargable (RC)+S, ipsilateral thalamic (VIM+VO) DBS, standard ET DBS, ipsilateral VO
Device · Procedure
Lead sponsor
University of Florida
Other
Eligibility
21 Years to 99 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2029
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Feb 9, 2026 · Synced Sep 7, 2026, 5:27 PM EDT
Completed Not applicable Interventional Results available

Wearable Sensor for Responsive DBS for ET

NCT03051178
View directory record Official record
Conditions
Essential Tremor
Interventions
Responsive deep brain stimulation
Device
Lead sponsor
University of Florida
Other
Eligibility
21 Years to 90 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
2
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Apr 18, 2024 · Synced Sep 7, 2026, 5:27 PM EDT
Completed Phase 2 Interventional Results available

Evaluate SAGE-547 in Participants With Essential Tremor

NCT02277106
View directory record Official record
Conditions
Essential Tremor
Interventions
SAGE-547, Placebo
Drug
Lead sponsor
Sage Therapeutics
Industry
Eligibility
35 Years to 75 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
2
States / cities
Bingham Farms, Michigan • Raleigh, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 28, 2022 · Synced Sep 7, 2026, 5:27 PM EDT
Completed Phase 2 Interventional

Octanol to Treat Essential Tremor

NCT00080366
View directory record Official record
Conditions
Essential Tremor
Interventions
1-Octanol
Drug
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
21 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2007
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 3, 2007 · Synced Sep 7, 2026, 5:27 PM EDT