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Showing 1–24 of 228 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Tremors Clear all
Active, not recruiting Not applicable Interventional

Long-Term Transcutaneous Stimulation and Essential Tremor: A PET Study

NCT03778060
View directory record Official record
Conditions
Essential Tremor
Interventions
Cala TWO stimulator
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
21 Years to 70 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 29, 2026 · Synced Sep 1, 2026, 7:44 PM EDT
Completed Not applicable Interventional Results available

rTMS Therapy for Primary Orthostatic Tremor

NCT02441985
View directory record Official record
Conditions
Primary Orthostatic Tremor
Interventions
Magstim RapidStim2, Sham Magstim RapidStim2, Fullerton Advanced Balance (FAB) Scale, Timed "Up & Go" Test (TUG) test, 10m walk test, Tremor electrophysiology, Cerebellar-brain Inhibition (CBI)
Device · Other
Lead sponsor
University of Florida
Other
Eligibility
30 Years to 75 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Apr 1, 2025 · Synced Sep 1, 2026, 7:44 PM EDT
Recruiting No phase listed Observational

Clinical Outcomes for Deep Brain Stimulation

NCT03992625
View directory record Official record
Conditions
Parkinson Disease, Essential Tremor, Dystonia
Interventions
Deep Brain Stimulation
Device
Lead sponsor
Washington University School of Medicine
Other
Eligibility
Not listed
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2030
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jun 19, 2019 · Synced Sep 1, 2026, 7:44 PM EDT
Withdrawn Phase 2Phase 3 Interventional

Dexmedetomidine Effects on Microelectrode Recording in Deep Brain Stimulation

NCT00608231
View directory record Official record
Conditions
Parkinson's Disease, Essential Tremor, Dystonia
Interventions
Dexmedetomidine Hydrochloride Infusion, Normal Saline
Drug
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jun 30, 2014 · Synced Sep 1, 2026, 7:44 PM EDT
Completed Not applicable Interventional

Physiology, Imaging and Modeling of Essential Tremor

NCT03811405
View directory record Official record
Conditions
Essential Tremor, Parkinson Disease, Dystonia
Interventions
Active biphasic pulse stimulation---Home Settings, Active biphasic pulse stimulation---VIN Biphasic, Active biphasic pulse stimulation---Stimulator Off
Device
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 80 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
2
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jun 25, 2025 · Synced Sep 1, 2026, 7:44 PM EDT
Completed Not applicable Interventional Results available

Comparison of Botulinum Toxin Injections in Forearm FLexor Plus EXtensor Muscles vs. Flexor Muscles Alone for Treatment of Essential Hand Tremor(FLEX-D ET)

NCT02909907
View directory record Official record
Conditions
Essential Tremor
Interventions
Botulinum toxin, Placebo
Drug · Other
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated May 7, 2019 · Synced Sep 1, 2026, 7:44 PM EDT
Completed No phase listed Observational

Neurotransmitter Measurements Using (WINCS) During Deep Brain Stimulation Neurosurgery

NCT01705301
View directory record Official record
Conditions
Essential Tremor, Parkinson's Disease, Dystonia
Interventions
WINCS
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 90 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2017
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 2, 2017 · Synced Sep 1, 2026, 7:44 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Biomarkers in Neural Disorders

NCT02761707
View directory record Official record
Conditions
Parkinson's Disease, Alzheimer's Disease, Progressive Supranuclear Palsy, Essential Tremor, Multiple System Atrophy, Drug Induced Parkinson's Disease, Diffuse Lewy Body Disease, Myasthenia Gravis, Spinal Cord Injuries
Interventions
Electrical Brainstem Responses, Olfactory Tests, Visual Deprivation, Peripheral Nerve Stimulation
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 80 Years
Enrollment
54 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 17, 2019 · Synced Sep 1, 2026, 7:44 PM EDT
Completed No phase listed Observational

Physiological Brain Atlas Development

NCT01210534
View directory record Official record
Conditions
Parkinson Disease, Dystonia, Tremors, Obsessive Compulsive Disorder, Depression
Interventions
No intervention
Other
Lead sponsor
Ohio State University
Other
Eligibility
7 Years to 90 Years
Enrollment
456 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2021
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 12, 2023 · Synced Sep 1, 2026, 7:44 PM EDT
Completed Phase 3 Interventional Results available

Switching Study of Kidney Transplant Patients With Tremor to LCP-Tacro (STRATO)

NCT01438710
View directory record Official record
Conditions
Renal Failure, Tremors
Interventions
Prograf, LCP-Tacro
Drug
Lead sponsor
Veloxis Pharmaceuticals
Industry
Eligibility
18 Years to 65 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
10
States / cities
Los Angeles, California • San Diego, California • Aurora, Colorado + 7 more
Source: ClinicalTrials.gov public record
Updated Sep 30, 2015 · Synced Sep 1, 2026, 7:44 PM EDT
Completed Phase 1Phase 2 Interventional Results available

Trial of Cannabis for Essential Tremor

NCT03805750
View directory record Official record
Conditions
Essential Tremor
Interventions
CBD/THC, Placebo oral capsule
Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
21 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Oct 12, 2022 · Synced Sep 1, 2026, 7:44 PM EDT
Completed Not applicable Interventional

Mapping the Target for the MRgFUS Treatment of Tremor

NCT04661241
View directory record Official record
Conditions
Tremor, Essential, Parkinson's Disease
Interventions
Automatic DRT/VIM target-recognition method using MR-SISET and ML approaches, Routine clinical MRI protocol
Other
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 14, 2022 · Synced Sep 1, 2026, 7:44 PM EDT
Not yet recruiting Phase 1 Interventional

Extended-release Sodium Oxybate (Lumryz) in Spasmodic Dysphonia and Voice Tremor

NCT07041203
View directory record Official record
Conditions
Spasmodic Dysphonia, Laryngeal Dystonia, Voice Tremor
Interventions
sodium oxybate
Drug
Lead sponsor
Kristina Simonyan
Other
Eligibility
21 Years to 80 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 27, 2026 · Synced Sep 1, 2026, 7:44 PM EDT
Withdrawn No phase listed Observational

Optimizing DBS Electrode Placement and Programming

NCT01820390
View directory record Official record
Conditions
Parkinson's Disease, Essential Tremor
Interventions
Not listed
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 70 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
2
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Feb 19, 2014 · Synced Sep 1, 2026, 7:44 PM EDT
Completed Phase 2 Interventional

A Pilot Efficacy and Safety Study of ST101 in Essential Tremor

NCT01332695
View directory record Official record
Conditions
Essential Tremor
Interventions
ST101, Placebo
Drug
Lead sponsor
Sonexa Therapeutics, Inc.
Industry
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jan 5, 2012 · Synced Sep 1, 2026, 7:44 PM EDT
Completed No phase listed Observational

Deep Brain Stimulation Effects in Essential Tremor

NCT04581941
View directory record Official record
Conditions
Essential Tremor
Interventions
Not listed
Lead sponsor
University of Florida
Other
Eligibility
21 Years to 85 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Oct 8, 2024 · Synced Sep 1, 2026, 7:44 PM EDT
Recruiting Early Phase 1 Interventional Accepts healthy volunteers

Understanding Disorder-specific Neural Pathophysiology in Laryngeal Dystonia and Voice Tremor

NCT05216770
View directory record Official record
Conditions
Laryngeal Dystonia, Spasmodic Dysphonia, Tremor
Interventions
Brain imaging, Laryngeal sensory block with topical bupivacaine
Other · Drug
Lead sponsor
Massachusetts Eye and Ear Infirmary
Other
Eligibility
18 Years to 80 Years
Enrollment
165 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 1, 2025 · Synced Sep 1, 2026, 7:44 PM EDT
Recruiting Not applicable Interventional

Home Use Study of Targeted Mechanical Stimulation for Tremor Relief

NCT07078422
View directory record Official record
Conditions
Essential Tremor, Parkinson's Disease
Interventions
Encora Pulse
Device
Lead sponsor
Encora, Inc.
Industry
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 23, 2025 · Synced Sep 1, 2026, 7:44 PM EDT
Not listed Phase 3 Interventional

Two Separate But Identical Studies Evaluating the Safety and Efficacy of ALTROPANE® in the Use of SPECT Imaging for Upper Extremity Tremor

NCT00724906
View directory record Official record
Conditions
Parkinsonian Syndromes
Interventions
123 I - ALTROPANE®
Drug
Lead sponsor
Alseres Pharmaceuticals, Inc
Industry
Eligibility
40 Years to 80 Years
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Hopkinton, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 2, 2010 · Synced Sep 1, 2026, 7:44 PM EDT
Completed No phase listed Observational

123I-ALTROPANE® Reference Image Acquisition in Subjects With Diagnostically Uncertain Tremor

NCT00596908
View directory record Official record
Conditions
Upper Extremity Tremor
Interventions
Not listed
Lead sponsor
Alseres Pharmaceuticals, Inc
Industry
Eligibility
40 Years and older
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
7
States / cities
Birmingham, Alabama • Tucson, Arizona • Los Angeles, California + 4 more
Source: ClinicalTrials.gov public record
Updated May 28, 2009 · Synced Sep 1, 2026, 7:44 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

An Exploratory Investigation to Assess Changes in Quality of Life for Individuals With Type 2 Diabetes After Taking a Meal-replacement Shake.

NCT05129735
View directory record Official record
Conditions
Diabetes Mellitus, Type 2
Interventions
Meal replacement shake
Dietary Supplement
Lead sponsor
Teatis, Inc
Industry
Eligibility
18 Years to 75 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Santa Monica, California
Source: ClinicalTrials.gov public record
Updated Aug 22, 2024 · Synced Sep 1, 2026, 7:44 PM EDT
Terminated Not applicable Interventional

DBS of Posterior Subthalamic Area (PSA) and Ventral Intermediate Nucleus (VIM) in Essential Tremor (ET)

NCT05096572
View directory record Official record
Conditions
Essential Tremor
Interventions
VIM Stimulation, PSA Stimulation, VIM+PSA Stimulation
Device
Lead sponsor
St. Joseph's Hospital and Medical Center, Phoenix
Other
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Nov 21, 2023 · Synced Sep 1, 2026, 7:44 PM EDT
Not yet recruiting Early Phase 1 Interventional

Human Cognition During Surgery: Stimulation-based and Cholinergic Modulation

NCT07721272
View directory record Official record
Conditions
Epilepsy, Essential Tremor, Seizures, Memory Consolidation, Memory Disorders, Memory Replay, Memory Encoding, Cognitive Control, Motor Abilities
Interventions
Cobenfy KarXT pill (50/20 mg), Placebo
Drug
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 70 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jul 22, 2026 · Synced Sep 1, 2026, 7:44 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Transcranial Stimulation for Essential Tremor

NCT03025529
View directory record Official record
Conditions
Essential Tremor
Interventions
Transcranial Magnetic Stimulation, Sham Transcranial Magnetic Stimulation
Device
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years to 80 Years
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 18, 2017 · Synced Sep 1, 2026, 7:44 PM EDT