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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Tremors Clear all
Completed No phase listed Observational Accepts healthy volunteers

Battery-preserving Stimulation Patterns for Deep Brain Stimulation

NCT02569021
View directory record Official record
Conditions
Parkinsons Disease, Essential Tremor
Interventions
Biphasic DBS stimulation, Unified Parkinson's Disease Rating Scale, Tremor Rating Scale, Kinesia accelerometer, Trigno wireless system, GaitRite walking assessment.
Device · Other
Lead sponsor
University of Florida
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Oct 23, 2016 · Synced Sep 20, 2026, 5:10 AM EDT
Completed No phase listed Observational

Treatment of Alcohol Withdrawal Syndrome With Alpha-2 Agonists and/or Anticonvulsants

NCT05438641
View directory record Official record
Conditions
Alcohol Withdrawal Syndrome
Interventions
BZDP-Sparing Protocol, BZDP-Based Protocol
Drug
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Jun 29, 2022 · Synced Sep 20, 2026, 5:10 AM EDT
Withdrawn Phase 2 Interventional Accepts healthy volunteers

Acamprosate and Methazolamide for Essential Tremor

NCT06312800
View directory record Official record
Conditions
Essential Tremor
Interventions
Acamprosate, Placebo, Methazolamide
Drug
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years to 70 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
West Bloomfield, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 24, 2024 · Synced Sep 20, 2026, 5:10 AM EDT
Completed Not applicable Interventional Results available

Comparison of Botulinum Toxin Injections in Forearm FLexor Plus EXtensor Muscles vs. Flexor Muscles Alone for Treatment of Essential Hand Tremor(FLEX-D ET)

NCT02909907
View directory record Official record
Conditions
Essential Tremor
Interventions
Botulinum toxin, Placebo
Drug · Other
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated May 7, 2019 · Synced Sep 20, 2026, 5:10 AM EDT
Completed Phase 2 Interventional Results available

Effectiveness of Botox on Reducing Rest Tremor in Parkinson's Disease

NCT03301272
View directory record Official record
Conditions
Parkinson Disease
Interventions
Onabotulinumtoxin A Injection, Placebo
Drug · Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
45 Years to 80 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 16, 2020 · Synced Sep 20, 2026, 5:10 AM EDT
Recruiting Not applicable Interventional

Home Use Study of Targeted Mechanical Stimulation for Tremor Relief

NCT07078422
View directory record Official record
Conditions
Essential Tremor, Parkinson's Disease
Interventions
Encora Pulse
Device
Lead sponsor
Encora, Inc.
Industry
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 23, 2025 · Synced Sep 20, 2026, 5:10 AM EDT
Completed Not applicable Interventional

Automated Telehealth Diagnostics for Remote Parkinson Monitoring

NCT02152319
View directory record Official record
Conditions
Parkinson's Disease
Interventions
KHV reporting, Standard care
Device · Procedure
Lead sponsor
Great Lakes NeuroTechnologies Inc.
Industry
Eligibility
Not listed
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Apr 27, 2016 · Synced Sep 20, 2026, 5:10 AM EDT
Recruiting Not applicable Interventional

Motor Network Physiology

NCT04957095
View directory record Official record
Conditions
Parkinson Disease, Essential Tremor
Interventions
Apomorphine Injectable Solution, Subcortical Stimulation
Drug · Other
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 89 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2028
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jul 21, 2026 · Synced Sep 20, 2026, 5:10 AM EDT
Recruiting No phase listed Observational

Deep Brain Stimulation (DBS) Retrospective Outcomes Study

NCT03664609
View directory record Official record
Conditions
Parkinson Disease, Essential Tremor, Dystonia
Interventions
Deep Brain Stimulation
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
Not listed
Enrollment
5,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2028
U.S. locations
10
States / cities
Phoenix, Arizona • Moreno Valley, California • San Francisco, California + 7 more
Source: ClinicalTrials.gov public record
Updated Sep 2, 2026 · Synced Sep 20, 2026, 5:10 AM EDT
Recruiting No phase listed Observational

Analysis of Cutaneous Phosphorylated Alpha-Synuclein to Identify Patients at Risk of Progressing From Essential Tremor to Parkinson's Disease

NCT07428447
View directory record Official record
Conditions
Essential Tremor, Movement Disorders, Essential Tremor, Essential Tremor-plus
Interventions
Not listed
Lead sponsor
CND Life Sciences
Other
Eligibility
50 Years to 85 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
4
States / cities
Scottsdale, Arizona • Orlando, Florida • Louisville, Kentucky + 1 more
Source: ClinicalTrials.gov public record
Updated Sep 17, 2026 · Synced Sep 20, 2026, 5:10 AM EDT
Completed Not applicable Interventional

RWE Study Utilizing the Cala Trio Device in Patients With Essential Tremor

NCT05540626
View directory record Official record
Conditions
Essential Tremor
Interventions
Cala Trio
Device
Lead sponsor
Cala Health, Inc.
Industry
Eligibility
22 Years and older
Enrollment
276 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
San Mateo, California
Source: ClinicalTrials.gov public record
Updated May 6, 2025 · Synced Sep 20, 2026, 5:10 AM EDT
Recruiting Not applicable Interventional

Circadian Adaptive DBS in Essential Tremor

NCT06635811
View directory record Official record
Conditions
Essential Tremor, Essential Tremor (ET), Essential Tremor, Movement Disorders
Interventions
Circadian Adaptive DBS, Conventional DBS
Device
Lead sponsor
University of Florida
Other
Eligibility
21 Years to 89 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jul 29, 2026 · Synced Sep 20, 2026, 5:10 AM EDT
Recruiting Not applicable Interventional

Magnetoencephalography (MEG) Pilot Study

NCT07446192
View directory record Official record
Conditions
Essential Tremor
Interventions
MRI and fMRI scans, MEG, Sensor-based motor assessments, Clinical evaluations, Questionnaires and rating scales that
Diagnostic Test · Other
Lead sponsor
University of Florida
Other
Eligibility
50 Years to 84 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Sep 20, 2026, 5:10 AM EDT
Active, not recruiting Not applicable Interventional

RAD 1601: EDGE Radiosurgery for Intractable Essential Tremor and Tremor-Dominant Parkinson's Disease

NCT03305588
View directory record Official record
Conditions
Essential Tremor, Parkinson Disease
Interventions
Unframed Virtual Cone
Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 99 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2026
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Mar 8, 2026 · Synced Sep 20, 2026, 5:10 AM EDT
Recruiting Not applicable Interventional

Stimulating Specific Brain Areas (VOP/VIM) With Electricity to Improve Movement and Muscle Control

NCT07056361
View directory record Official record
Conditions
Movement Disorders (Incl Parkinsonism), Stroke, Traumatic Brain Injury, Brain Diseases, Parkinson Disease, Essential Tremor, Movement Disorders
Interventions
Direct cortical stimulation and deep brain stimulation of motor thalamus
Device
Lead sponsor
Jorge Gonzalez-Martinez
Other
Eligibility
18 Years to 75 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2030
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 17, 2026 · Synced Sep 20, 2026, 5:10 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Voice Tremor in Spasmodic Dysphonia: Central Mechanisms and Treatment Response

NCT01961297
View directory record Official record
Conditions
Spasmodic Dysphonia, Voice Tremor
Interventions
Sodium oxybate
Drug
Lead sponsor
Kristina Simonyan
Other
Eligibility
21 Years to 80 Years
Enrollment
53 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2017
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 21, 2017 · Synced Sep 20, 2026, 5:10 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Functional Neuroimaging Feedback for Focused Ultrasound Thalamotomy

NCT03560622
View directory record Official record
Conditions
Essential Tremor
Interventions
multi-modality neuroimaging
Device
Lead sponsor
Vibhor Krishna
Other
Eligibility
40 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 23, 2021 · Synced Sep 20, 2026, 5:10 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Shake It Up: Lipidomics of Lipoproteins and Diet

NCT04120220
View directory record Official record
Conditions
Overweight
Interventions
Heavy Cream, Soybean Oil
Other
Lead sponsor
USDA Grand Forks Human Nutrition Research Center
Federal
Eligibility
18 Years to 60 Years · Male only
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Grand Forks, North Dakota
Source: ClinicalTrials.gov public record
Updated Aug 3, 2022 · Synced Sep 20, 2026, 5:10 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Attention and Eye Movement in Parkinson's Disease

NCT06899022
View directory record Official record
Conditions
Essential Tremor, Parkinson's Disease (PD), Dystonias
Interventions
Normal therapeutic DBS, Reduced current DBS, Reduced frequency DBS
Other
Lead sponsor
University of Nebraska
Other
Eligibility
19 Years to 90 Years
Enrollment
138 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated May 4, 2026 · Synced Sep 20, 2026, 5:10 AM EDT
Completed Not applicable Interventional Results available

A Pilot Study of the Cala ONE Device for Essential Tremor

NCT03152136
View directory record Official record
Conditions
Essential Tremor
Interventions
Cala ONE device
Device
Lead sponsor
Cala Health, Inc.
Industry
Eligibility
22 Years to 80 Years
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
4
States / cities
Oakland, California • Denver, Colorado • Kansas City, Kansas + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 29, 2019 · Synced Sep 20, 2026, 5:10 AM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

Evaluating the Effects of an Oral Protein Supplement on Children's Growth Patterns

NCT06329388
View directory record Official record
Conditions
Growth Disorders, Dietary Exposure, Child Development, Bone Development Abnormal, Body Weight, Child Malnutrition
Interventions
TruHeight Growth Protein Shake
Dietary Supplement
Lead sponsor
TruHeight Vitamins
Industry
Eligibility
4 Years to 17 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Mar 25, 2024 · Synced Sep 20, 2026, 5:10 AM EDT
Completed Phase 2 Interventional Results available

A Study to Investigate the Efficacy and Safety of NT 201 (Botulinum Toxin) Compared With Placebo for the Treatment of Adult Participants With Essential Tremor in the Arm

NCT04766723
View directory record Official record
Conditions
Essential Tremor of the Upper Limb
Interventions
NT 201, Placebo
Drug
Lead sponsor
Merz Pharmaceuticals GmbH
Industry
Eligibility
18 Years and older
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
9
States / cities
Tampa, Florida • Omaha, Nebraska • Las Vegas, Nevada + 6 more
Source: ClinicalTrials.gov public record
Updated May 27, 2026 · Synced Sep 20, 2026, 5:10 AM EDT
Enrolling by invitation Not applicable Interventional

A Study of Wearable Device in Essential Tremor Patients

NCT05976074
View directory record Official record
Conditions
Essential Tremor
Interventions
Apple Watch, BrainRISE app
Device · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 28, 2025 · Synced Sep 20, 2026, 5:10 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Analysis and Suppression of Tremor During Grasp Using Ultrasound Imaging and Electrical Stimulation

NCT05308368
View directory record Official record
Conditions
Parkinson Disease, Essential Tremor
Interventions
Ultrasound Imaging, Electromyography, Inertial Measurement Units (IMU), Functional Electrical Stimulation (FES)
Device
Lead sponsor
North Carolina State University
Other
Eligibility
18 Years to 90 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Raleigh, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 26, 2025 · Synced Sep 20, 2026, 5:10 AM EDT