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Showing 1–24 of 26 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Ultra Processed Food Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Ultra-Processed Foods and Executive Function

NCT06518863
View directory record Official record
Conditions
Diet Habit
Interventions
Education
Behavioral
Lead sponsor
Oklahoma State University
Other
Eligibility
18 Years to 55 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Stillwater, Oklahoma
Source: ClinicalTrials.gov public record
Updated Feb 3, 2026 · Synced Sep 13, 2026, 3:42 AM EDT
Not yet recruiting Not applicable Interventional

Medically Tailored Meals to Reduce Ultra-processed Food Intake in Colorectal Cancer Survivors

NCT07701707
View directory record Official record
Conditions
Colorectal Cancer (Diagnosis)
Interventions
MTM: Medically tailored meals, MTM plus Fresh Produce, Control group
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 13, 2026 · Synced Sep 13, 2026, 3:42 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Dietary Guidelines for Americans-Ultra Processed Study

NCT07252037
View directory record Official record
Conditions
Overweight , Obesity, Class I Obesity
Interventions
Low-processed DGA Diet, Ultra-processed DGA Diet
Other
Lead sponsor
USDA Grand Forks Human Nutrition Research Center
Federal
Eligibility
18 Years to 65 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
1
States / cities
Grand Forks, North Dakota
Source: ClinicalTrials.gov public record
Updated Aug 6, 2026 · Synced Sep 13, 2026, 3:42 AM EDT
Completed Not applicable Interventional

Diet and Depression

NCT06252701
View directory record Official record
Conditions
Depression, Major Depressive Disorder, Weight Gain, Obesity, Metabolic Syndrome
Interventions
Reduction of Ultra-processed foods
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 80 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Nov 20, 2025 · Synced Sep 13, 2026, 3:42 AM EDT
Completed Not applicable Interventional

You Are What You Eat: Food as a Risk Factor and a Treatment for Depression

NCT06242665
View directory record Official record
Conditions
Depression
Interventions
Low UPF Meals (Study Provided), Low UPF Nutritional Guidance, Low UPF Snacks (Study Provided)
Other
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
47 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 19, 2026 · Synced Sep 13, 2026, 3:42 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effect of Ultra Processed Versus Unprocessed Diets on Energy Intake

NCT03407053
View directory record Official record
Conditions
Healthy Diet
Interventions
Ultra-processed diet, Unprocessed diet
Dietary Supplement
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
18 Years to 50 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 28, 2021 · Synced Sep 13, 2026, 3:42 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Click & Pick Study

NCT07422922
View directory record Official record
Conditions
Chronic Disease
Interventions
Suite of healthy food policies
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 17, 2026 · Synced Sep 13, 2026, 3:42 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Metabolomics-Driven Insights Into Ultra-Processed Foods

NCT07717970
View directory record Official record
Conditions
Diet, Food and Nutrition
Interventions
UPF Test Diet A: Starchy, refined grains, UPF Test Diet B: Meat, fish, and bread products, UPF Diet C: Dairy products, including cheese and cream
Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
20 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2027 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 20, 2026 · Synced Sep 13, 2026, 3:42 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Perceptions of and Reactions to Ultra-Processed Menu Label Designs

NCT07214805
View directory record Official record
Conditions
Food Choices
Interventions
Ultra-Processed, Red, Icon-plus-text Labels, Contains Food Additives, Red, Icon-plus-text Labels, Warning Ultra-Processed, Red, Icon-plus-text Labels, Warning UPF, Red, Icon-plus-text Labels, Ultra-Processed, Yellow, Icon-plus-text Labels, Contains Food Additives, Yellow, Icon-plus-text Labels, Warning Ultra-Processed, Yellow, Icon-plus-text Labels, Warning UPF, Yellow, Icon-plus-text Labels, Ultra-Processed, Red, Text-only Labels, Contains Food Additives, Red, Text-only Labels, Warning Ultra-Processed, Red, Text-only Labels, Warning UPF, Red, Text-only Labels, Ultra-Processed, Yellow, Text-only Labels, Contains Food Additives, Yellow, Text-only Labels, Warning Ultra-Processed, Yellow, Text-only Labels, Warning UPF, Yellow, Text-only Labels
Behavioral
Lead sponsor
Johns Hopkins Bloomberg School of Public Health
Other
Eligibility
18 Years and older
Enrollment
14,720 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 10, 2025 · Synced Sep 13, 2026, 3:42 AM EDT
Recruiting Not applicable Interventional

Effects of Ultra Processed Food on Intestinal Energy Harvest

NCT06853288
View directory record Official record
Conditions
Obesity and Overweight
Interventions
Diet containing 80% ultra processed foods, Diet containing 20% ultra processed foods
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
25 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 2, 2025 · Synced Sep 13, 2026, 3:42 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

The Breakfast Study: How Different Aspects of Food Affect Eating

NCT07525050
View directory record Official record
Conditions
Healthy Individuals
Interventions
UPF breakfast/MPF breakfast, MPF breakfast/UPF breakfast
Other
Lead sponsor
USDA Grand Forks Human Nutrition Research Center
Federal
Eligibility
18 Years to 50 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Grand Forks, North Dakota
Source: ClinicalTrials.gov public record
Updated Jun 10, 2026 · Synced Sep 13, 2026, 3:42 AM EDT
Recruiting Not applicable Interventional

Biobehavioral Reward Responses Associated With Consumption of Nutritionally Diverse Ultra-Processed Foods

NCT05437809
View directory record Official record
Conditions
Obesity, Overeating, Food Addiction
Interventions
Intake of nutritionally diverse ultra-processed foods
Other
Lead sponsor
Oregon Research Institute
Other
Eligibility
18 Years to 65 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 11, 2026 · Synced Sep 13, 2026, 3:42 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Impacts of Warning Labels on Ultra-Processed Foods

NCT06296355
View directory record Official record
Conditions
Health Behavior, Diet, Healthy
Interventions
Health Warning Label, Identity Warning Label, Barcode Label
Behavioral · Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 55 Years
Enrollment
4,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 14, 2024 · Synced Sep 13, 2026, 3:42 AM EDT
Completed Not applicable Interventional Results available

Effect of Ultra-processed Versus Unprocessed Diets on Energy Metabolism

NCT05290064
View directory record Official record
Conditions
Healthy Diet, Obesity
Interventions
Ultra-processed food, high energy density (UPF HL), Ultra-processed food, both low (UPF LL), Ultra-processed food, both high (UPF HH), Unprocessed food diet (UNF LL)
Other
Lead sponsor
National Institutes of Health Clinical Center (CC)
NIH
Eligibility
18 Years to 60 Years
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 11, 2026 · Synced Sep 13, 2026, 3:42 AM EDT
Recruiting No phase listed Observational

Dietary Tracking in Heart Failure

NCT07649148
View directory record Official record
Conditions
Heart Failure, NYHA Class II Heart Failure, NYHA Class III Heart Failure
Interventions
Limiting Ultraprocessed Food (UPF) in Diet
Behavioral
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2040
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 16, 2026 · Synced Sep 13, 2026, 3:42 AM EDT
Recruiting Not applicable Interventional

Ultra Crave: An Investigation of Ultra-Processed Food

NCT06044285
View directory record Official record
Conditions
Food Addiction
Interventions
Low UP (meals provided), Low UP (self-guided), Active Control
Other
Lead sponsor
University of Michigan
Other
Eligibility
22 Years to 60 Years
Enrollment
210 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated May 18, 2026 · Synced Sep 13, 2026, 3:42 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Ultra-processed Food Consumption, Gut Microbiota, and Glucose Homeostasis

NCT05358171
View directory record Official record
Conditions
Insulin Sensitivity, 24-hour Glucose Control
Interventions
HIgh UPF controlled diet, No UPF controlled diet
Other
Lead sponsor
Virginia Polytechnic Institute and State University
Other
Eligibility
40 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Blacksburg, Virginia
Source: ClinicalTrials.gov public record
Updated Jan 13, 2026 · Synced Sep 13, 2026, 3:42 AM EDT
Recruiting No phase listed Observational

Effects of Processed Foods on Brain Reward Circuitry and Food Cue Learning

NCT06165952
View directory record Official record
Conditions
Ultra-processed Foods (UP)
Interventions
Not listed
Lead sponsor
Stanford University
Other
Eligibility
13 Years to 15 Years
Enrollment
162 participants
Timeline
2024 – 2029
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Apr 23, 2026 · Synced Sep 13, 2026, 3:42 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Ultra-Processed Foods, Palatability, Appetite, and Gastrointestinal Transit

NCT07600281
View directory record Official record
Conditions
Appetite, Gastrointestinal Transit, Food Processing, Food Palatability, Eating Behavior
Interventions
Palatable Ultra-Processed Food Meal, Unpalatable Ultra-Processed Food Meal, Palatable Non-Ultra-Processed Food Meal, Unpalatable Non-Ultra-Processed Food Meal
Other
Lead sponsor
Purdue University
Other
Eligibility
18 Years to 60 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
West Lafayette, Indiana
Source: ClinicalTrials.gov public record
Updated May 21, 2026 · Synced Sep 13, 2026, 3:42 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Dismantling the U.S. Social Norm of the "Kids' Food" Archetype (REACH Project)

NCT06266533
View directory record Official record
Conditions
Food Selection, Environmental Exposure
Interventions
Conventional Ultra-processed Food Nutrition Education, Arts-based Ultra-processed Food Nutrition Education
Behavioral
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years to 85 Years · Female only
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Newark, New Jersey
Source: ClinicalTrials.gov public record
Updated Jul 23, 2025 · Synced Sep 13, 2026, 3:42 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Analysis of MicroBial Metabolites After Eating Refined Food

NCT04308473
View directory record Official record
Conditions
Dietary Habits
Interventions
Ultra-processed Food Meal, Whole Food Meal
Other
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2026
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 24, 2026 · Synced Sep 13, 2026, 3:42 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Ultra-processed Food Consumption and Health Pilot Study

NCT07318064
View directory record Official record
Conditions
Obesity & Overweight
Interventions
Purple Diet, Ultra-processed diet
Behavioral
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
18 Years to 50 Years
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Jun 28, 2026 · Synced Sep 13, 2026, 3:42 AM EDT
Recruiting Not applicable Interventional

GF-NOURISH (Gluten Free Nutrition Optimization Through Ultra-processed Food Reduction and Improved Strategies for Health)

NCT06356220
View directory record Official record
Conditions
Celiac Disease in Children, Nutrition Disorder, Child
Interventions
Gluten-Free Diet Education
Other
Lead sponsor
Boston Children's Hospital
Other
Eligibility
2 Years to 18 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 11, 2026 · Synced Sep 13, 2026, 3:42 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of UPF Warning Labels on Social Media Among Teens and Young Adults

NCT07227519
View directory record Official record
Conditions
Nutrition, Healthy Diet, Food Preferences
Interventions
UPF Warning Labels, No Labels (Control)
Behavioral
Lead sponsor
University of Tennessee
Other
Eligibility
13 Years to 29 Years
Enrollment
1,012 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Aug 9, 2026 · Synced Sep 13, 2026, 3:42 AM EDT