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ClinicalTrials.gov public records Last synced Oct 20, 2026, 2:40 PM EDT

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Showing 25–48 of 48 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Underage Drinking Clear all
Completed Not applicable Interventional Accepts healthy volunteers

A Community-Based Strategy for Preventing Underage Drinking

NCT02448134
View directory record Official record
Conditions
Alcohol Abuse
Interventions
Youth Access
Behavioral
Lead sponsor
Oregon Research Institute
Other
Eligibility
13 Years to 19 Years
Enrollment
7,379 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2020
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Sep 16, 2020 · Synced Oct 20, 2026, 2:40 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Project e-PBI+ - Parent Intervention to Reduce College Student Drinking and Cannabis Use

NCT05345951
View directory record Official record
Conditions
Underage Drinking, Cannabis Use, Drinking, Teen, Drinking, College, College Drinking, Teen Drinking
Interventions
e-PBI
Behavioral
Lead sponsor
Penn State University
Other
Eligibility
18 Years to 19 Years
Enrollment
1,980 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 23, 2026 · Synced Oct 20, 2026, 2:40 PM EDT
Not listed Not applicable Interventional

Computer Adaptation of Screening, Brief MET Intervention to Reduce Teen Drinking

NCT01881841
View directory record Official record
Conditions
Alcohol Abuse, Tobacco Use Disorder, Substance Use
Interventions
cMET
Behavioral
Lead sponsor
Boston Children's Hospital
Other
Eligibility
14 Years to 20 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 20, 2017 · Synced Oct 20, 2026, 2:40 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

REAL Parenting Alcohol and Substance Use App

NCT03932097
View directory record Official record
Conditions
Underage Drinking, Alcohol Use, Underage
Interventions
REAL Parenting, Active Control Materials
Behavioral · Other
Lead sponsor
Real Prevention, LLC
Industry
Eligibility
15 Years to 18 Years
Enrollment
306 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Clifton, New Jersey
Source: ClinicalTrials.gov public record
Updated May 25, 2023 · Synced Oct 20, 2026, 2:40 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Parent Intervention to Reduce College Student Drinking and Consequences

NCT04247191
View directory record Official record
Conditions
Underage Drinking, Driving Under the Influence, Drinking, Teen, Drinking, College
Interventions
P-Chat+, PBI
Behavioral
Lead sponsor
Penn State University
Other
Eligibility
18 Years to 19 Years
Enrollment
2,061 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 28, 2026 · Synced Oct 20, 2026, 2:40 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Effectiveness of Brief Intervention in Primary Care for Diverse Young People (Chat)

NCT06699251
View directory record Official record
Conditions
Adolescent Drinking, Cannabis Use
Interventions
Chat, Enhanced Usual Care
Behavioral
Lead sponsor
RAND
Other
Eligibility
12 Years to 19 Years
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
3
States / cities
Commerce, California • North Hollywood, California • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 9, 2026 · Synced Oct 20, 2026, 2:40 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Evaluation of Global Smart Drinking Goals Initiative

NCT03262259
View directory record Official record
Conditions
Binge Drinking, Underage Drinking, Drinking and Driving, Alcohol-Related Harms
Interventions
GSDG multi-component intervention
Behavioral
Lead sponsor
HBSA
Other
Eligibility
12 Years and older
Enrollment
36,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2025
U.S. locations
1
States / cities
Calverton, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 3, 2025 · Synced Oct 20, 2026, 2:40 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Online Mindfulness-Based College for Young Adults

NCT04733300
View directory record Official record
Conditions
Depressive Symptoms, Loneliness, Sedentary Behavior, Mindfulness, Physical Activity, Diet, Sleep, Emotional Regulation, Alcohol Consumption, Youth, Stress, Psychological
Interventions
Mindfulness-Based College for Young Adults, Health Education for Young Adults
Behavioral · Other
Lead sponsor
Eric Loucks
Other
Eligibility
18 Years to 29 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Feb 2, 2021 · Synced Oct 20, 2026, 2:40 PM EDT
Recruiting Not applicable Interventional

Evaluating Caregiver Involvement in Primary Care-Based Brief Interventions for Adolescent Alcohol Use Problems

NCT06593652
View directory record Official record
Conditions
Alcohol Use, Adolescent, Mild Alcohol Use Disorder, Mild Substance Use Disorder
Interventions
Teen Intervene - Adolescent Only, Teen Intervene with Caregiver Session, Family Check Up
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
12 Years to 17 Years
Enrollment
615 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Jan 2, 2026 · Synced Oct 20, 2026, 2:40 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Experimental Test of Facebook Social Drinking Norms on Adolescent Alcohol Use

NCT03159286
View directory record Official record
Conditions
Feedback, Psychological, Underage Alcohol Use, Risk-Taking
Interventions
Abstainer, Abstainer + User, Control
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
15 Years to 20 Years
Enrollment
306 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Nov 21, 2019 · Synced Oct 20, 2026, 2:40 PM EDT
Recruiting Not applicable Interventional

Centralized Virtual SBIRT for Pediatric Primary Care

NCT06486688
View directory record Official record
Conditions
Adolescent Alcohol Use, Mental Health Issue, Alcohol Related Disorders, Adolescents
Interventions
Centralized Virtual SBIRT
Behavioral
Lead sponsor
Kaiser Permanente
Other
Eligibility
12 Years to 17 Years
Enrollment
22,320 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Pleasanton, California
Source: ClinicalTrials.gov public record
Updated Jul 8, 2024 · Synced Oct 20, 2026, 2:40 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Project U Connect - Optimizing Brief Alcohol Intervention for Underage Drinkers in the ER

NCT01051141
View directory record Official record
Conditions
Alcohol Misuse
Interventions
Computer-delivered Brief Intervention (CBI), Intervener-delivered Brief Intervention (IBI), Adapted Motivational Enhancement Therapy (AMET)
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
14 Years to 20 Years
Enrollment
870 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 22, 2015 · Synced Oct 20, 2026, 2:40 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Native Spirit: Significant Aim 3: Intervention

NCT06785311
View directory record Official record
Conditions
Substance Use, Self Esteem, Youth Drinking, Prevention, Suicide
Interventions
Native Spirit After-School Program
Behavioral
Lead sponsor
Arizona State University
Other
Eligibility
12 Years to 17 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
2
States / cities
Scottsdale, Arizona • Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Feb 17, 2026 · Synced Oct 20, 2026, 2:40 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Culturally Enhancing a Motivational Interviewing Intervention For Latinx Adolescents

NCT03947177
View directory record Official record
Conditions
Underage Alcohol Use, Smoking, Non-Tobacco Products
Interventions
GMIT+
Behavioral
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
10 Years to 16 Years
Enrollment
59 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Jun 30, 2022 · Synced Oct 20, 2026, 2:40 PM EDT
Completed Phase 2 Interventional Results available

N-Acetylcysteine for Adolescent Alcohol Use Disorder

NCT03707951
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
N-acetylcysteine, Placebo oral capsule
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
13 Years to 25 Years
Enrollment
126 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jan 8, 2025 · Synced Oct 20, 2026, 2:40 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Testing a Brief Substance Misuse Preventative Intervention for Parents/Guardians of 5th-7th Grade Students

NCT03925220
View directory record Official record
Conditions
Substance-Related Disorders, Underage Drinking, Drug Use
Interventions
The SUPPER Project, Improving nutrition and physical activity among youth
Behavioral
Lead sponsor
Tufts University
Other
Eligibility
9 Years to 14 Years
Enrollment
402 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 9, 2025 · Synced Oct 20, 2026, 2:40 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Parent-Focused Alcohol Prevention Program for Hispanic Families in Faith-Based Settings

NCT07869550
View directory record Official record
Conditions
Alcohol Use, Underage Drinking, Parenting Intervention, Prevention, Faith-Based, Implementation Science
Interventions
Guiando Buenas Decisiones (GBD)
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
12 Years and older
Enrollment
440 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Oct 9, 2026 · Synced Oct 20, 2026, 2:40 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Family Intervention for Teen Drinking in the ER

NCT01229748
View directory record Official record
Conditions
Alcohol Abuse
Interventions
Standard Care, Multidimensional Family Therapy, Family Motivational Interviewing Intervention
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
12 Years to 18 Years
Enrollment
104 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2015
U.S. locations
3
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated May 1, 2015 · Synced Oct 20, 2026, 2:40 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Alcohol Feedback, Reflection and Morning Evaluation

NCT05509218
View directory record Official record
Conditions
Youth Drinking, Alcohol Drinking
Interventions
Mobile-delivered personalized feedback
Behavioral
Lead sponsor
Brown University
Other
Eligibility
18 Years to 29 Years
Enrollment
152 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jun 16, 2026 · Synced Oct 20, 2026, 2:40 PM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers Results available

Effects of Topiramate on Adolescent Alcohol Use: Efficacy and Mechanisms

NCT01641445
View directory record Official record
Conditions
Alcohol Drinking
Interventions
Topiramate, Placebo
Drug
Lead sponsor
Brown University
Other
Eligibility
14 Years to 24 Years
Enrollment
82 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2017
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Oct 20, 2020 · Synced Oct 20, 2026, 2:40 PM EDT
Completed Phase 2 Interventional Results available

Enhancing the Effects of Alcohol Treatment With Lamotrigine

NCT04770493
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Lamotrigine, Placebo
Drug
Lead sponsor
Brown University
Other
Eligibility
16 Years to 24 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jun 13, 2025 · Synced Oct 20, 2026, 2:40 PM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Norms Re-education to Promote Engagement in Parent-based Interventions

NCT06871982
View directory record Official record
Conditions
Underage Drinking
Interventions
PNF+ PBI, SNMC+ PBI, PH+ PBI
Behavioral
Lead sponsor
Loyola Marymount University
Other
Eligibility
17 Years to 20 Years
Enrollment
2,040 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jul 7, 2026 · Synced Oct 20, 2026, 2:40 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Healthy Families Bright Futures Program

NCT06309134
View directory record Official record
Conditions
Alcohol Drinking, Violence in Adolescence
Interventions
Healthy Families Bright Futures Program
Behavioral
Lead sponsor
University of Colorado, Colorado Springs
Other
Eligibility
15 Years to 18 Years
Enrollment
122 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Colorado Springs, Colorado
Source: ClinicalTrials.gov public record
Updated Sep 1, 2026 · Synced Oct 20, 2026, 2:40 PM EDT
Enrolling by invitation Not applicable Interventional

Optimizing and Advancing SBIRT in Schools

NCT06206161
View directory record Official record
Conditions
Adolescent Drinking, Adolescent Substance Use, Risk Behavior, Health
Interventions
Indicated Prevention, Clinical Staff, Selective Prevention, Expanded Paraprofessional Workforce
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
14 Years to 19 Years
Enrollment
21,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 26, 2025 · Synced Oct 20, 2026, 2:40 PM EDT