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Showing 1–24 of 208 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Upper Extremity Pain Clear all
Completed No phase listed Observational

Clinical Study on a Novel Minimally Invasive Posterior Sacroiliac Fusion Device

NCT04423120
View directory record Official record
Conditions
Chronic Pain
Interventions
Not listed
Lead sponsor
PainTEQ, LLC
Industry
Eligibility
21 Years to 70 Years
Enrollment
159 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Tyler, Texas
Source: ClinicalTrials.gov public record
Updated May 21, 2024 · Synced Sep 3, 2026, 7:15 AM EDT
Completed Not applicable Interventional Results available

Virtual Reality for Pain in Acute Orthopedic Injuries

NCT05552430
View directory record Official record
Conditions
Injuries, Injury Arm, Injury;Sports, Injury, Knee, Injury Wrist, Injury, Ankle, Injury Foot, Injury, Hand, Injury Finger, Injury Leg
Interventions
RelieveVRx
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 21, 2024 · Synced Sep 3, 2026, 7:15 AM EDT
Completed Not applicable Interventional Results available

Epidural Spinal Cord Stimulation for Sensory Restoration and Phantom Limb Pain in Upper-Limb Amputees

NCT02684201
View directory record Official record
Conditions
Phantom Limb
Interventions
Boston Scientific Stimulator Lead
Device
Lead sponsor
Lee Fisher, PhD
Other
Eligibility
18 Years to 70 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2024
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 7, 2025 · Synced Sep 3, 2026, 7:15 AM EDT
Active, not recruiting No phase listed Observational

Intracept Intraosseous Basivertebral Nerve Ablation

NCT05660512
View directory record Official record
Conditions
Low Back Pain
Interventions
Intracept Procedure
Procedure
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
150 participants
Timeline
2020 – 2026
U.S. locations
3
States / cities
Farmington, Utah • Salt Lake City, Utah • South Jordan, Utah
Source: ClinicalTrials.gov public record
Updated Apr 12, 2026 · Synced Sep 3, 2026, 7:15 AM EDT
Completed Not applicable Interventional Results available

Corticosteroid Injection for Common Upper Extremity Problems

NCT00438672
View directory record Official record
Conditions
Lateral Elbow Pain
Interventions
Placebo Injection, Steroid (dexamethasone) Injection
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2010
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 27, 2012 · Synced Sep 3, 2026, 7:15 AM EDT
Recruiting Not applicable Interventional

A Prospective Study of a Modified Lumbar Puncture (LP) Procedure That Reduces Post-Lumbar Puncture Headaches (PLPH) in Patients

NCT06062446
View directory record Official record
Conditions
Post-Lumbar Puncture Headache
Interventions
Modified Lumbar Puncture
Procedure
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 12, 2025 · Synced Sep 3, 2026, 7:15 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Recovery From Plantar Heel Pain Using the Fascial Distortion Model a Pilot Study

NCT04571073
View directory record Official record
Conditions
Plantar Fasciitis of Both Feet
Interventions
Fascial Distortion Model
Procedure
Lead sponsor
Eisenhower Army Medical Center
Federal
Eligibility
18 Years to 65 Years
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Fort Gordon, Georgia
Source: ClinicalTrials.gov public record
Updated Feb 24, 2021 · Synced Sep 3, 2026, 7:15 AM EDT
Completed Phase 3 Interventional Results available

Single-arm Study to Assess the Safety of Hydromorphone Hydrochloride by Intrathecal Administration

NCT01709747
View directory record Official record
Conditions
Chronic Pain
Interventions
Hydromorphone Hydrochloride, Programmable Implantable pump
Drug · Device
Lead sponsor
Piramal Critical Care, Ltd.
Industry
Eligibility
18 Years to 75 Years
Enrollment
364 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 24, 2021 · Synced Sep 3, 2026, 7:15 AM EDT
Suspended Phase 2 Interventional

A Four Arm Study to Evaluate the Safety and Efficacy of 3 Different Doses of RVX-100 Versus Placebo in Subjects With Irritable Bowel Syndrome Accompanied by Diarrhea (IBS-D)

NCT01076699
View directory record Official record
Conditions
Irritable Bowel Syndrome
Interventions
0.075 mg RVX-100, 0.125 mg RVX-100, 0.250 mg RVX-100, placebo
Drug
Lead sponsor
Revogenex, Inc.
Industry
Eligibility
18 Years to 75 Years
Enrollment
192 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Chevy Chase, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 18, 2010 · Synced Sep 3, 2026, 7:15 AM EDT
Completed Not applicable Interventional Results available

Cryoanalgesia to Treat Phantom Limb Pain Following Above-Knee Amputation

NCT06071715
View directory record Official record
Conditions
Amputation, Surgical, Amputation, Traumatic, Phantom Limb Pain, Phantom Pain Following Amputation of Lower Limb
Interventions
ACTIVE cryoneurolysis, SHAM cryoneurolysis
Device
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Apr 7, 2026 · Synced Sep 3, 2026, 7:15 AM EDT
Completed Phase 2 Interventional Results available

Four Arm Safety & Efficacy With Antipyrine and Benzocaine Otic Solution in Children With Acute Otitis Media

NCT02037893
View directory record Official record
Conditions
Acute Otitis Media
Interventions
Antipyrine and Benzocaine otic solution, Antipyrine Otic Solution, Benzocaine Otic Solution, Placebo Otic solution
Drug
Lead sponsor
Currax Pharmaceuticals
Industry
Eligibility
2 Months to 12 Years
Enrollment
112 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
10
States / cities
Mesa, Arizona • Tucson, Arizona • Bentonville, Arkansas + 5 more
Source: ClinicalTrials.gov public record
Updated Aug 6, 2024 · Synced Sep 3, 2026, 7:15 AM EDT
Completed Not applicable Interventional Results available

Effect of Vibration Exercise on Upper Limb Strength, Function, and Pain

NCT02998021
View directory record Official record
Conditions
Spinal Cord Injuries
Interventions
Vibrating Dumbbell, Standard Dumbbell
Device
Lead sponsor
Alicia Koontz
Other
Eligibility
18 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 22, 2019 · Synced Sep 3, 2026, 7:15 AM EDT
Completed No phase listed Observational

Study of Post Operative Pain in Endometrial Cancer Robotic Versus Laparotomy

NCT00909896
View directory record Official record
Conditions
Endometrial Cancer
Interventions
Not listed
Lead sponsor
Ohio State University Comprehensive Cancer Center
Other
Eligibility
18 Years to 85 Years · Female only
Enrollment
142 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 1, 2018 · Synced Sep 3, 2026, 7:15 AM EDT
Withdrawn Not applicable Interventional

Video-based Consensus Opinion for Hand and Upper Extremity Problems

NCT02204605
View directory record Official record
Conditions
Pain
Interventions
Video-based Consensus Opinion
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 21, 2016 · Synced Sep 3, 2026, 7:15 AM EDT
Completed Not applicable Interventional

RecoveryPlus Telerehab Platform Pilot Study

NCT05804500
View directory record Official record
Conditions
Heart Diseases, Angina, Stable, Angina Pectoris, Myocardial Ischemia, Myocardial Infarction, Coronary Artery Disease, Coronary Artery Stenosis, Valve Heart Disease, Valve Disease, Heart
Interventions
Cardiac Telerehabilitation (CTR) via the RecoveryPlus platform
Behavioral
Lead sponsor
NODEHealth Foundation
Other
Eligibility
45 Years and older
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jan 18, 2024 · Synced Sep 3, 2026, 7:15 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Auriculotherapy - Pain Management of Aspiration Abortion

NCT03896022
View directory record Official record
Conditions
Abortion in First Trimester
Interventions
Acupressure with Beads, Acupuncture with Needles, Placebo Adhesive Disks
Device
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older · Female only
Enrollment
177 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 8, 2021 · Synced Sep 3, 2026, 7:15 AM EDT
Completed Phase 4 Interventional Results available

Study to Evaluate the Efficacy of Rotigotine on Parkinson's Disease-Associated Pain

NCT01744496
View directory record Official record
Conditions
Advanced Idiopathic Parkinson's Disease
Interventions
Rotigotine, Placebo
Drug
Lead sponsor
UCB BIOSCIENCES GmbH
Industry
Eligibility
18 Years and older
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
10
States / cities
Gilbert, Arizona • Sunnyvale, California • Tampa, Florida + 7 more
Source: ClinicalTrials.gov public record
Updated Apr 30, 2015 · Synced Sep 3, 2026, 7:15 AM EDT
Completed No phase listed Observational

Safety and Effectiveness of Magnetic Peripheral Nerve Stimulation for the Treatment of Chemotherapy Induced Neuropathy

NCT05935956
View directory record Official record
Conditions
Neuralgia, Neuropathic Pain, Chemotherapy-induced Peripheral Neuropathy
Interventions
Magnetic Peripheral Nerve Stimulation
Device
Lead sponsor
NeuraLace Medical, Inc.
Industry
Eligibility
18 Years to 85 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 10, 2024 · Synced Sep 3, 2026, 7:15 AM EDT
Enrolling by invitation Not applicable Interventional

Evaluation and Modification of Surgeon Ergonomics in the Operation Room Using Artificial Intelligence Analytics

NCT06576570
View directory record Official record
Conditions
Work Related Upper Limb Disorder, Musculoskeletal Pain
Interventions
Education presentation of surgical ergonomics, Summary of Ergonomic Measurement System
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 99 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
2
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Nov 19, 2025 · Synced Sep 3, 2026, 7:15 AM EDT
Completed Not applicable Interventional

Single-arm, Open-label, Phase II Trial of HD-tDCS in Fibromyalgia Patients

NCT01842009
View directory record Official record
Conditions
Fibromyalgia, Chronic Pain
Interventions
High Definition transcranial Direct Current Stimulation
Device
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 85 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Charlestown, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 23, 2020 · Synced Sep 3, 2026, 7:15 AM EDT
Recruiting Not applicable Interventional

This Project is a Three-arm RCT Evaluating Two, Single-session Behavioral Interventions for Adults With Chronic Musculoskeletal Pain (CMP) -- 1) Brief Mindfulness-Oriented Recovery Enhancement (B-MORE) vs. Empowered Relief (ER) -- Relative to the Traditional 8-week Version of MORE.

NCT07193095
View directory record Official record
Conditions
Chronic Musculoskeletal Pain
Interventions
Brief Mindfulness Oriented Recovery Enhancement, Empowered Relief, Mindfulness Oriented Recovery Enhancement
Behavioral
Lead sponsor
Florida State University
Other
Eligibility
18 Years and older
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Sep 24, 2025 · Synced Sep 3, 2026, 7:15 AM EDT
Not yet recruiting Not applicable Interventional

Combination Versus Alone Liposomal Bupivacaine Blocks in Minimally Invasive Thoracic Surgery-1

NCT07254650
View directory record Official record
Conditions
Lung Cancer (Diagnosis)
Interventions
Arm 1 "LipoB-I": Liposomal Bupivacaine via Multi-Level Intercostal Nerve Block, Arm 2 "LipoB-S": Liposomal Bupivacaine via Serratus Anterior Plane Block, Arm 3 "LipoB-C": Liposomal Bupivacaine Administered via Combination Block
Procedure
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Aug 25, 2026 · Synced Sep 3, 2026, 7:15 AM EDT
Completed Phase 3 Interventional Results available

Safety and Efficacy Study of Hydromorphone Hydrochloride by Intrathecal Administration

NCT01709721
View directory record Official record
Conditions
Management of Chronic Pain
Interventions
Hydromorphone Hydrochloride, Programmable Implantable pump
Drug · Device
Lead sponsor
Piramal Critical Care, Ltd.
Industry
Eligibility
18 Years to 75 Years
Enrollment
153 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 3, 2021 · Synced Sep 3, 2026, 7:15 AM EDT
Completed Phase 3 Interventional

A Study Assessing the Safety and Efficacy of Dextenza® for the Treatment of Ocular Pain and Inflammation Following Surgery for Pediatric Cataract

NCT04539548
View directory record Official record
Conditions
Cataract
Interventions
Dextenza Ophthalmic Insert, Prednisolone acetate ophthalmic suspension USP 1%
Drug
Lead sponsor
Ocular Therapeutix, Inc.
Industry
Eligibility
0 Years to 5 Years
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
14
States / cities
Aurora, Colorado • Fort Collins, Colorado • Jacksonville, Florida + 11 more
Source: ClinicalTrials.gov public record
Updated Apr 14, 2024 · Synced Sep 3, 2026, 7:15 AM EDT