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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Vaping Teens Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

Impact of Vaping Prevention Advertisements

NCT04836455
View directory record Official record
Conditions
Vaping
Interventions
The FDA's The REal Cost vaping prevention ads - Health harms theme, The FDA's The Real Cost vaping prevention ads - Addiction theme, Neutral vaping ads
Behavioral
Lead sponsor
UNC Lineberger Comprehensive Cancer Center
Other
Eligibility
13 Years to 17 Years
Enrollment
1,565 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 23, 2024 · Synced Jun 10, 2026, 2:24 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Hippocampal Network Changes Following Mindfulness Training in Tobacco Vaping Adolescents in an Open-label, Pilot Study

NCT06503159
View directory record Official record
Conditions
Vaping Teens, Healthy Volunteers
Interventions
Mindfulness-based Stress Reduction (MBSR) Program, functional magnetic resonance imaging (fMRI)
Behavioral · Other
Lead sponsor
National Institute on Drug Abuse (NIDA)
NIH
Eligibility
13 Years to 18 Years
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 26, 2026 · Synced Jun 10, 2026, 2:24 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Guiding Good Choices for Health

NCT04040153
View directory record Official record
Conditions
Adolescent Substance Use
Interventions
Guiding Good Choices
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
11 Years to 12 Years
Enrollment
3,636 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2025
U.S. locations
3
States / cities
Oakland, California • Aurora, Colorado • Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 2, 2024 · Synced Jun 10, 2026, 2:24 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Virtual Reality Game to Prevent E-cigarette and Cannabis Vaping

NCT07413432
View directory record Official record
Conditions
Cannabis, Vaping, Emotion Regulation
Interventions
Virtual reality videogame intervention for vaping prevention
Behavioral
Lead sponsor
Yale University
Other
Eligibility
11 Years to 15 Years
Enrollment
62 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 16, 2026 · Synced Jun 10, 2026, 2:24 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Flavors and E-cigarette Effects in Adolescent Smokers- STUDY 1

NCT02179034
View directory record Official record
Conditions
Nicotine Dependence, Other Tobacco Product
Interventions
Nicotine, Low Dose Menthol, High Dose Menthol
Drug · Other
Lead sponsor
Yale University
Other
Eligibility
18 Years to 20 Years
Enrollment
59 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated May 3, 2020 · Synced Jun 10, 2026, 2:24 PM EDT
Completed Phase 4 Interventional Results available

Varenicline for Nicotine Vaping Cessation in Adolescents

NCT05367492
View directory record Official record
Conditions
Vaping, Nicotine Dependence
Interventions
Double Blind Varenicline, Double Blind Placebo, QuitVaping, This Is Quitting
Drug · Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
16 Years to 25 Years
Enrollment
261 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 26, 2025 · Synced Jun 10, 2026, 2:24 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Point-of-Care Ultrasound (POCUS) Findings and Impact on Vaping

NCT06335329
View directory record Official record
Conditions
Vaping
Interventions
Discussion of point-of-care ultrasound lung findings
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
12 Years to 18 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Feb 16, 2026 · Synced Jun 10, 2026, 2:24 PM EDT
Not yet recruiting Not applicable Interventional

AI-Enhanced App-based Intervention for Adolescent E-cigarette Cessation

NCT06965296
View directory record Official record
Conditions
Nicotine Dependence, Cigarettes
Interventions
AI-enhanced smartphone app, AI-enhanced smartphone app, but with delayed access
Behavioral
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
14 Years to 20 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Feb 18, 2026 · Synced Jun 10, 2026, 2:24 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Media Literacy for High School Tobacco Prevention

NCT05120466
View directory record Official record
Conditions
Adolescent Behavior, Tobacco Use, E-Cig Use
Interventions
AD IT UP media literacy intervention, Usual health education curriculum
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
13 Years to 17 Years
Enrollment
147 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 1, 2024 · Synced Jun 10, 2026, 2:24 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Development of UP2UTobacco for High School Youth

NCT05396911
View directory record Official record
Conditions
Tobacco Use Cessation, Tobacco Use, Electronic Cigarette Use
Interventions
UP2UTobacco
Behavioral
Lead sponsor
University of Virginia
Other
Eligibility
14 Years to 15 Years
Enrollment
597 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 19, 2026 · Synced Jun 10, 2026, 2:24 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Pittsburgh and Rural Area High School Tobacco Prevention

NCT05081843
View directory record Official record
Conditions
Adolescent Behavior, Tobacco Use, E-Cig Use
Interventions
AD IT UP media literacy intervention, Usual health education curriculum
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
13 Years to 17 Years
Enrollment
318 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 3, 2025 · Synced Jun 10, 2026, 2:24 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

A Virtual Reality E-cigarette Prevention and Emotion Regulation Intervention for Adolescents

NCT07460622
View directory record Official record
Conditions
E-cigarette Use/Vaping Prevention, Nicotine Dependence Prevention, Adolescent Mental Health
Interventions
Virtual Reality E-Cigarette Prevention Program
Behavioral
Lead sponsor
Yale University
Other
Eligibility
11 Years to 15 Years
Enrollment
1,251 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 9, 2026 · Synced Jun 10, 2026, 2:24 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of the Be Vape Free Curriculum of the Tobacco Prevention Toolkit

NCT05493982
View directory record Official record
Conditions
E-cigarette Use
Interventions
Stanford Vaping Prevention curriculum
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
10 Years to 20 Years
Enrollment
2,779 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated May 26, 2026 · Synced Jun 10, 2026, 2:24 PM EDT
Recruiting Not applicable Interventional

Parents Helping Parents for Youth Vaping Cessation

NCT07207850
View directory record Official record
Conditions
Implementation Science, Engagement, Patient, E Cigarette Use, Peer Support, Vaping Teens, Vaping Cessation, Parent Support
Interventions
Parents Helping Parents program
Behavioral
Lead sponsor
University of Nebraska
Other
Eligibility
15 Years to 18 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated May 25, 2026 · Synced Jun 10, 2026, 2:24 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Human Factors Validation and Usability Testing of the IKE Age-Gating System

NCT06952569
View directory record Official record
Conditions
Vaping, Underage
Interventions
IKE System
Other
Lead sponsor
IKE Tech
Industry
Eligibility
18 Years and older
Enrollment
102 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
4
States / cities
Los Angeles, California • Chicago, Illinois • New York, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 30, 2025 · Synced Jun 10, 2026, 2:24 PM EDT
Completed Not applicable Interventional

Influencer E-Cigarette and Cannabis Marketing: a Survey-Based Experiment Among Adolescents

NCT06919263
View directory record Official record
Conditions
Electronic Nicotine Delivery Systems
Interventions
Influencer marketing
Behavioral
Lead sponsor
University of Southern California
Other
Eligibility
16 Years to 17 Years
Enrollment
1,462 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 8, 2025 · Synced Jun 10, 2026, 2:24 PM EDT
Enrolling by invitation No phase listed Observational Accepts healthy volunteers

Understanding Vape Marketing Study

NCT07129265
View directory record Official record
Conditions
E-cigarette, Vaping, Tobacco, Nicotine, Adolescent Behavior, Video Information, Digital Education Interventions
Interventions
Working group, Focus group
Other
Lead sponsor
Boston Children's Hospital
Other
Eligibility
13 Years and older
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 18, 2025 · Synced Jun 10, 2026, 2:24 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Perceived Effectiveness of Vaping Prevention Ads Among Adolescents and Young Adults

NCT07116837
View directory record Official record
Conditions
Vaping
Interventions
Vaping prevention video ads
Behavioral
Lead sponsor
UNC Lineberger Comprehensive Cancer Center
Other
Eligibility
13 Years to 20 Years
Enrollment
3,500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 27, 2026 · Synced Jun 10, 2026, 2:24 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Vaping Prevention and Vaping in Youth (Vapechat)

NCT06003439
View directory record Official record
Conditions
Vaping, Smoking Cessation
Interventions
Virtual Reality Program, VR Program
Behavioral
Lead sponsor
Boston University
Other
Eligibility
13 Years to 19 Years
Enrollment
119 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 6, 2024 · Synced Jun 10, 2026, 2:24 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Implementation and Dissemination of an Evidence-Based Tobacco Product Use Prevention Videogame Intervention With Adolescents

NCT03815591
View directory record Official record
Conditions
Smoking Cessation, Smoking
Interventions
smokeSCREEN web-based game
Device
Lead sponsor
Yale University
Other
Eligibility
10 Years to 16 Years
Enrollment
560 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 21, 2022 · Synced Jun 10, 2026, 2:24 PM EDT
Recruiting Phase 1 Interventional

Testing the Feasibility and Acceptability of Social Media and Digital Therapeutics to Decrease Vaping Behaviors

NCT05994209
View directory record Official record
Conditions
Nicotine Vaping, Nicotine Use Disorder
Interventions
quitSTART Mobile Application, Chatbot Feature in quitSTART Mobile Application
Device · Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
15 Years to 25 Years
Enrollment
189 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 12, 2026 · Synced Jun 10, 2026, 2:24 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

A Hybrid Program to Prevent Substance Use Risk Among Upper Elementary School Students Using a Positive Youth Development Approach

NCT07162155
View directory record Official record
Conditions
Vaping, E Cig Use, Prescription Drug Misuse
Interventions
School-based Hybrid Intervention to Prevent Vaping and Prescription Drug Misuse
Behavioral
Lead sponsor
Christopher Williams
Industry
Eligibility
7 Years to 11 Years
Enrollment
3,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
White Plains, New York
Source: ClinicalTrials.gov public record
Updated Sep 8, 2025 · Synced Jun 10, 2026, 2:24 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Impact of E-Cigarette Prevention Messages on Adolescents

NCT05985538
View directory record Official record
Conditions
Vaping Behavior
Interventions
Vaping prevention text messages, Wellness behaviors text messages
Behavioral
Lead sponsor
UNC Lineberger Comprehensive Cancer Center
Other
Eligibility
13 Years to 20 Years
Enrollment
480 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 21, 2025 · Synced Jun 10, 2026, 2:24 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Adolescent Inpatient Tobacco and ENDS Intervention

NCT05936099
View directory record Official record
Conditions
Vaping, Smoking
Interventions
E-cigarette & Tobacco Use Treatment Intervention
Behavioral
Lead sponsor
Children's Mercy Hospital Kansas City
Other
Eligibility
14 Years to 21 Years
Enrollment
144 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Feb 8, 2026 · Synced Jun 10, 2026, 2:24 PM EDT