- Conditions
- E-cigarette Use/Vaping Prevention, Nicotine Dependence Prevention, Adolescent Mental Health
- Interventions
- Virtual Reality E-Cigarette Prevention Program
- Behavioral
- Lead sponsor
- Yale University
- Other
- Eligibility
- 11 Years to 15 Years
- Enrollment
- 1,251 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2026 – 2028
- U.S. locations
- 1
- States / cities
- New Haven, Connecticut
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Showing 25–48
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- Conditions
- Nicotine Vaping
- Interventions
- Kick-Nic! mobile phone application, NCI Quit Vaping website
- Behavioral
- Lead sponsor
- Yale University
- Other
- Eligibility
- 12 Years to 19 Years
- Enrollment
- 306 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2025 – 2029
- U.S. locations
- 1
- States / cities
- New Haven, Connecticut
- Conditions
- Vaping, E Cig Use, Prescription Drug Misuse
- Interventions
- School-based Hybrid Intervention to Prevent Vaping and Prescription Drug Misuse
- Behavioral
- Lead sponsor
- Christopher Williams
- Industry
- Eligibility
- 7 Years to 11 Years
- Enrollment
- 3,000 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2026 – 2028
- U.S. locations
- 1
- States / cities
- White Plains, New York
- Conditions
- Healthy Volunteers, Vaping Teens
- Interventions
- Not listed
- Lead sponsor
- National Institute on Drug Abuse (NIDA)
- NIH
- Eligibility
- 13 Years to 120 Years
- Enrollment
- 726 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2025
- U.S. locations
- 1
- States / cities
- Baltimore, Maryland
- Conditions
- Perceptions of Tobacco Products
- Interventions
- Each intervention will be a picture of a social media post. The posts will vary (in a 3X2 factorial design) the type of flavor described and whether concealability is described.
- Behavioral
- Lead sponsor
- University of Southern California
- Other
- Eligibility
- 14 Years to 17 Years
- Enrollment
- 4,500 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2025 – 2028
- U.S. locations
- 1
- States / cities
- Los Angeles, California
- Conditions
- Vaping
- Interventions
- Vaping prevention video ads
- Behavioral
- Lead sponsor
- UNC Lineberger Comprehensive Cancer Center
- Other
- Eligibility
- 13 Years to 20 Years
- Enrollment
- 3,113 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2025 – 2026
- U.S. locations
- 1
- States / cities
- Chapel Hill, North Carolina
- Conditions
- Vaping
- Interventions
- Discussion of point-of-care ultrasound lung findings
- Behavioral
- Lead sponsor
- Medical University of South Carolina
- Other
- Eligibility
- 12 Years to 18 Years
- Enrollment
- 90 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2024 – 2026
- U.S. locations
- 1
- States / cities
- Charleston, South Carolina
- Conditions
- Smoking Cessation, Smoking
- Interventions
- smokeSCREEN web-based game
- Device
- Lead sponsor
- Yale University
- Other
- Eligibility
- 10 Years to 16 Years
- Enrollment
- 560 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019 – 2021
- U.S. locations
- 1
- States / cities
- New Haven, Connecticut
- Conditions
- E-cigarette Use, Vaping
- Interventions
- Peer Messaging, Peer Coaching via Text, Gamification, E-Cigarette Cessation Materials
- Behavioral · Other
- Lead sponsor
- University of Massachusetts, Worcester
- Other
- Eligibility
- 13 Years to 19 Years
- Enrollment
- 71 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2022 – 2024
- U.S. locations
- 1
- States / cities
- Worcester, Massachusetts
- Conditions
- Vaping Behaviors
- Interventions
- Health Impacts of E-cigarettes, Mind Matters: The Body's Response to Nicotine, Tobacco, and Vaping, The Villainous Vape
- Behavioral
- Lead sponsor
- University of Rochester
- Other
- Eligibility
- 12 Years to 17 Years
- Enrollment
- 90 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2026 – 2027
- U.S. locations
- 1
- States / cities
- Rochester, New York
- Conditions
- Vaping, Vaping Cessation
- Interventions
- Behavioral: Quitting Program (TIQ)
- Device
- Lead sponsor
- St. Jude Children's Research Hospital
- Other
- Eligibility
- 13 Years to 24 Years
- Enrollment
- 539 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2027
- U.S. locations
- 1
- States / cities
- Memphis, Tennessee
- Conditions
- Vaping
- Interventions
- The FDA's The REal Cost vaping prevention ads - Health harms theme, The FDA's The Real Cost vaping prevention ads - Addiction theme, Neutral vaping ads
- Behavioral
- Lead sponsor
- UNC Lineberger Comprehensive Cancer Center
- Other
- Eligibility
- 13 Years to 17 Years
- Enrollment
- 1,565 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021
- U.S. locations
- 1
- States / cities
- Chapel Hill, North Carolina
- Conditions
- Tobacco Use Cessation, Tobacco Use, Electronic Cigarette Use
- Interventions
- UP2UTobacco
- Behavioral
- Lead sponsor
- University of Virginia
- Other
- Eligibility
- 14 Years to 15 Years
- Enrollment
- 597 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2022 – 2026
- U.S. locations
- 1
- States / cities
- Charlottesville, Virginia
- Conditions
- Vaping, Nicotine Dependence
- Interventions
- Double Blind Varenicline, Double Blind Placebo, QuitVaping, This Is Quitting
- Drug · Behavioral
- Lead sponsor
- Massachusetts General Hospital
- Other
- Eligibility
- 16 Years to 25 Years
- Enrollment
- 261 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2024
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Vaping
- Interventions
- Exposure to Influencer Age and Context Variations in E-Cigarette Marketing
- Other
- Lead sponsor
- University of Southern California
- Other
- Eligibility
- 14 Years to 17 Years
- Enrollment
- 6,000 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2027 – 2030
- U.S. locations
- 1
- States / cities
- Los Angeles, California
- Conditions
- Vaping Teens, Vaping Behaviors, Vaping Cessation, Tobacco Use Disorder
- Interventions
- E-cigarette Cessation Manual
- Behavioral
- Lead sponsor
- Florida International University
- Other
- Eligibility
- 14 Years to 18 Years
- Enrollment
- 120 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2028
- U.S. locations
- 1
- States / cities
- Miami, Florida
- Conditions
- Implementation Science, Engagement, Patient, E Cigarette Use, Peer Support, Vaping Teens, Vaping Cessation, Parent Support
- Interventions
- Parents Helping Parents program
- Behavioral
- Lead sponsor
- University of Nebraska
- Other
- Eligibility
- 15 Years to 18 Years
- Enrollment
- 200 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2027
- U.S. locations
- 1
- States / cities
- Omaha, Nebraska
- Conditions
- Adolescent Substance Use
- Interventions
- Guiding Good Choices
- Behavioral
- Lead sponsor
- University of Washington
- Other
- Eligibility
- 11 Years to 12 Years
- Enrollment
- 3,636 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019 – 2025
- U.S. locations
- 3
- States / cities
- Oakland, California • Aurora, Colorado • Detroit, Michigan
- Conditions
- Vaping, Cessation, Tobacco
- Interventions
- This is Quitting, Assessment only control, Waitlist control
- Behavioral · Other
- Lead sponsor
- Truth Initiative
- Other
- Eligibility
- 13 Years to 17 Years
- Enrollment
- 1,681 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021 – 2023
- U.S. locations
- 1
- States / cities
- Washington D.C., District of Columbia
- Conditions
- Vaping, Adolescent, Electronic Cigarette Use, Nicotine, Cannabis
- Interventions
- Vaping Device Labeling
- Other
- Lead sponsor
- University of Southern California
- Other
- Eligibility
- 11 Years to 19 Years
- Enrollment
- 3,048 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2025
- U.S. locations
- 1
- States / cities
- Los Angeles, California
- Conditions
- Vaping
- Interventions
- Acted-Out Narrative Ads, Non-Acted-Out Narrative Testimonial Ads, Neutral Control Videos
- Behavioral
- Lead sponsor
- UNC Lineberger Comprehensive Cancer Center
- Other
- Eligibility
- 13 Years to 20 Years
- Enrollment
- 1,910 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2026 – 2028
- U.S. locations
- 2
- States / cities
- Fairfield, Connecticut • Chapel Hill, North Carolina
- Conditions
- Vaping, Adolescent Behavior, Communication Research
- Interventions
- Tailored
- Other
- Lead sponsor
- Abramson Cancer Center at Penn Medicine
- Other
- Eligibility
- 13 Years to 20 Years
- Enrollment
- 1,155 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2024 – 2025
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- Depressive Symptoms, Depression, Adolescent Behavior
- Interventions
- Behavioral Activation Therapy app, Treatment as Usual
- Behavioral
- Lead sponsor
- Medical University of South Carolina
- Other
- Eligibility
- 16 Years to 20 Years
- Enrollment
- 106 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021 – 2023
- U.S. locations
- 1
- States / cities
- Charleston, South Carolina
- Conditions
- Vaping
- Interventions
- Influencer marketing
- Other
- Lead sponsor
- University of Southern California
- Other
- Eligibility
- 13 Years to 17 Years
- Enrollment
- 664 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024
- U.S. locations
- 1
- States / cities
- Seattle, Washington