Independent directory Public ClinicalTrials.gov records United States
Clinical Trials Finder
Objective public record navigation
Search Results

Search by objective public record fields.

Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results are retrieved from ClinicalTrials.gov and synchronized into the directory. Search pages remain noindex by default.

Clear filters
ClinicalTrials.gov public records Last synced Jul 21, 2026, 4:40 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 85 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Condition: Vascular Closure Clear all
Completed Not applicable Interventional

PerQseal®+ Early Feasibility Study

NCT05163548
View directory record Official record
Conditions
Percutaneous Large Hole Vascular Closure
Interventions
PerQseal Plus Device
Device
Lead sponsor
Vivasure Medical Limited
Industry
Eligibility
19 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
5
States / cities
Ridgewood, New Jersey • New York, New York • Stony Brook, New York + 2 more
Source: ClinicalTrials.gov public record
Updated Apr 25, 2023 · Synced Jul 21, 2026, 4:40 PM EDT
Terminated Not applicable Interventional Results available

VenaSeal Spectrum: Global Post-Market Randomized Controlled Trial

NCT03820947
View directory record Official record
Conditions
Venous Reflux
Interventions
VenaSeal™ System, Endothermal Ablation (ETA), Surgical Stripping
Device · Procedure
Lead sponsor
Medtronic Endovascular
Industry
Eligibility
18 Years and older
Enrollment
506 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
12
States / cities
Prescott Valley, Arizona • Tucson, Arizona • Fresno, California + 9 more
Source: ClinicalTrials.gov public record
Updated Dec 29, 2025 · Synced Jul 21, 2026, 4:40 PM EDT
Completed Not applicable Interventional Results available

Comparing Synthetic Hybrid-Scale Fiber Matrix With Standard of Care in Treating Diabetic Foot Ulcers

NCT04918784
View directory record Official record
Conditions
Diabetic Foot Ulcer
Interventions
Restrata®, Wound Dressing
Device
Lead sponsor
Acera Surgical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Hoffman Estates, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 27, 2023 · Synced Jul 21, 2026, 4:40 PM EDT
Terminated Not applicable Interventional Results available

Celliant Socks to Increase Tissue Oxygenation and Complete Wound Closure in Diabetic Foot Wounds

NCT04709419
View directory record Official record
Conditions
Diabetic Foot Ulcer
Interventions
Celliant Diabetic Medical Socks, Control (placebo) Medical Socks
Device
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
22 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jan 14, 2025 · Synced Jul 21, 2026, 4:40 PM EDT
Completed Not applicable Interventional Results available

Cross-Seal Closure Device IDE Trial - Study of the Cross-SealTM Suture-Mediated Vascular Closure Device System

NCT03756558
View directory record Official record
Conditions
Vascular Closure
Interventions
Cross-Seal System
Device
Lead sponsor
Terumo Medical Corporation
Industry
Eligibility
18 Years and older
Enrollment
147 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
20
States / cities
Denver, Colorado • Jacksonville, Florida • Tampa, Florida + 15 more
Source: ClinicalTrials.gov public record
Updated Sep 14, 2025 · Synced Jul 21, 2026, 4:40 PM EDT
Active, not recruiting No phase listed Observational

Amulet™ ADVANCE LAA

NCT05997446
View directory record Official record
Conditions
Atrial Fibrillation, Stroke, Bleeding
Interventions
Left atrial appendage occlusion (LAAO)
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
610 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
16
States / cities
Phoenix, Arizona • Little Rock, Arkansas • Jacksonville, Florida + 13 more
Source: ClinicalTrials.gov public record
Updated Sep 30, 2025 · Synced Jul 21, 2026, 4:40 PM EDT
Recruiting No phase listed Observational

Abbott Vascular Medical Device Registry

NCT04573660
View directory record Official record
Conditions
Acute Myocardial Infarction, Restenoses, Coronary, Coronary Artery Lesions, Venous Embolism, Arterial Embolism
Interventions
Coronary and peripheral stents, Pacing catheters, Vascular plugs, Measurement and imaging (FFR and OCT), Peripheral dilatation catheters, Coronary dilatation catheters, Coronary and peripheral guidewires, Vessel closure/compression devices, Vascular access introducers
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
3,784 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2031
U.S. locations
7
States / cities
Birmingham, Alabama • Little Rock, Arkansas • Los Angeles, California + 4 more
Source: ClinicalTrials.gov public record
Updated Jul 2, 2025 · Synced Jul 21, 2026, 4:40 PM EDT
Terminated Phase 3 Interventional Accepts healthy volunteers

EffiCacy, Safety and ToLErability of a Novel Ocular ANtiseptic for Ocular Use (CLEAN)

NCT05127525
View directory record Official record
Conditions
Diabetic Macular Edema, Branch Retinal Vein Occlusion, Glaucoma/Closed Angle Glaucoma
Interventions
IRX-101, Control
Drug
Lead sponsor
iRenix Medical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated May 23, 2022 · Synced Jul 21, 2026, 4:40 PM EDT
Completed Not applicable Interventional

Fluoroscopy Guided Femoral Arterial Access

NCT00222430
View directory record Official record
Conditions
Vascular Access
Interventions
Fluoroscopy, Active Comparator
Procedure
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years and older
Enrollment
990 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
2
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Mar 27, 2012 · Synced Jul 21, 2026, 4:40 PM EDT
Completed Not applicable Interventional Results available

Evaluation of Safety and Efficacy of the Mynx Control Venous Vascular Closure Device 6F-12F vs Manual Compression

NCT05554471
View directory record Official record
Conditions
Venous Vascular Closure
Interventions
MYNX CONTROL™ Venous Vascular Closure Device 6F-12F
Device
Lead sponsor
Cordis US Corp.
Industry
Eligibility
18 Years and older
Enrollment
352 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
14
States / cities
Phoenix, Arizona • Lakewood, Colorado • Miami, Florida + 10 more
Source: ClinicalTrials.gov public record
Updated Apr 23, 2025 · Synced Jul 21, 2026, 4:40 PM EDT
Recruiting Phase 4 Interventional

Evaluation of the Efficacy of STRATAFIX for Neurosurgical Cranial and Spine Procedures

NCT07225101
View directory record Official record
Conditions
Wound Closure, Brain Tumor Adult, Spine, Neurovascular, Hemorrhagic Stroke, Intracerebral, Traumatic Brain Injury
Interventions
STRATAFIX PDS and Monocryl suture
Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Lansing, Michigan
Source: ClinicalTrials.gov public record
Updated Nov 4, 2025 · Synced Jul 21, 2026, 4:40 PM EDT
Recruiting Not applicable Interventional

Use of 4D-ICE in Conjunction With TEE for Left Atrial Appendage Closure

NCT06061757
View directory record Official record
Conditions
Atrial Fibrillation, Stroke
Interventions
Imaging guidance with TEE and ICE for Left atrial appendage closure
Device
Lead sponsor
Kansas City Heart Rhythm Research Foundation
Other
Eligibility
18 Years to 80 Years
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Overland Park, Kansas
Source: ClinicalTrials.gov public record
Updated Aug 27, 2025 · Synced Jul 21, 2026, 4:40 PM EDT
Terminated Phase 4 Interventional

Restore Calcium Alginate Dressing, Silver vs Aquacel Ag in the Treatment of Critically Colonized Venous Leg Ulcers

NCT01396304
View directory record Official record
Conditions
Venous Ulcer, Infection
Interventions
Restore Calcium Alginate Dressing, AquaCel Ag Wound Dressing
Device
Lead sponsor
Hollister Wound Care LLC
Industry
Eligibility
18 Years and older
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
5
States / cities
St. Petersburg, Florida • Shreveport, Louisiana • Holmdel, New Jersey + 2 more
Source: ClinicalTrials.gov public record
Updated Feb 14, 2013 · Synced Jul 21, 2026, 4:40 PM EDT
Completed Not applicable Interventional Results available

Randomized, Controlled Multicenter Trial of Vacuum Assisted Closure Therapy™ in Diabetic Foot Ulcers

NCT00432965
View directory record Official record
Conditions
Diabetic Foot Ulcers
Interventions
Moist Wound Therapy, VAC Therapy
Device
Lead sponsor
KCI USA, Inc
Industry
Eligibility
18 Years and older
Enrollment
335 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2008
U.S. locations
24
States / cities
Phoenix, Arizona • Tucson, Arizona • Castro Valley, California + 17 more
Source: ClinicalTrials.gov public record
Updated Oct 15, 2024 · Synced Jul 21, 2026, 4:40 PM EDT
Completed Not applicable Interventional

SDRM® vs. Collagen for Diabetic Foot Ulcers

NCT05883098
View directory record Official record
Conditions
Diabetic Foot, Ulcer Foot, Wound Heal
Interventions
Wound debridement, Wound closure matrix application
Procedure · Device
Lead sponsor
Polymedics Innovations Inc.
Industry
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Circleville, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 27, 2023 · Synced Jul 21, 2026, 4:40 PM EDT
Not listed Phase 2Phase 3 Interventional

Evaluation of the STARFlex® Septal Closure System in Patients With a Stroke or TIA Due to the Possible Passage of a Clot of Unknown Origin Through a Patent Foramen Ovale (PFO)

NCT00201461
View directory record Official record
Conditions
Patent Foramen Ovale, Stroke, Ischemic Attack, Transient
Interventions
STARFlex septal closure system, Best medical therapy
Device · Drug
Lead sponsor
NMT Medical
Industry
Eligibility
18 Years to 60 Years
Enrollment
900 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2010
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 29, 2008 · Synced Jul 21, 2026, 4:40 PM EDT
Completed Not applicable Interventional Results available

GORE® Septal Occluder Device for Patent Foramen Ovale (PFO) Closure in Stroke Patients

NCT00738894
View directory record Official record
Conditions
Stroke, Transient Ischemic Attack
Interventions
Septal Occluder Device, Antiplatelet Medical Therapy
Device · Drug
Lead sponsor
W.L.Gore & Associates
Industry
Eligibility
18 Years to 60 Years
Enrollment
664 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2020
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 19, 2020 · Synced Jul 21, 2026, 4:40 PM EDT
Completed Not applicable Interventional Results available

RESPECT Trial - (Rapid Extravascular Sealing Via PercutanEous Collagen ImplanT)

NCT01297322
View directory record Official record
Conditions
Surgical Wound
Interventions
Manual compression, Cardiva VASCADE™ Vascular Closure System
Other · Device
Lead sponsor
Cardiva Medical, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
420 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
20
States / cities
Fairhope, Alabama • Newark, Delaware • Melbourne, Florida + 17 more
Source: ClinicalTrials.gov public record
Updated Jan 21, 2020 · Synced Jul 21, 2026, 4:40 PM EDT
Completed Not applicable Interventional Results available

MANTA Percutaneous Vascular Closure Device - The SAFE MANTA Study

NCT02908880
View directory record Official record
Conditions
Femoral Arteriotomy Closure
Interventions
MANTA vascular closure device
Device
Lead sponsor
Essential Medical, Inc.
Industry
Eligibility
21 Years and older
Enrollment
263 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
18
States / cities
San Diego, California • Washington D.C., District of Columbia • Evanston, Illinois + 14 more
Source: ClinicalTrials.gov public record
Updated Sep 24, 2019 · Synced Jul 21, 2026, 4:40 PM EDT
Completed Not applicable Interventional

PerQseal® Impella Early Feasibility Study

NCT04818541
View directory record Official record
Conditions
Percutaneous Large Hole Vascular Closure
Interventions
PPCI, Cardiogenic shock
Device
Lead sponsor
Vivasure Medical Limited
Industry
Eligibility
19 Years and older
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
4
States / cities
Ridgewood, New Jersey • Buffalo, New York • Stony Brook, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 25, 2023 · Synced Jul 21, 2026, 4:40 PM EDT
Terminated Phase 3 Interventional

Multi-Center, Prospective, Randomized Controlled Trial Evaluating SkinTE® in the Treatment of Wagner 2 DFUs

NCT05372809
View directory record Official record
Conditions
Diabetic Foot
Interventions
SkinTE, Control
Biological · Other
Lead sponsor
PolarityTE
Industry
Eligibility
18 Years and older
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
13
States / cities
Fresno, California • Los Angeles, California • Hollywood, Florida + 8 more
Source: ClinicalTrials.gov public record
Updated Feb 25, 2024 · Synced Jul 21, 2026, 4:40 PM EDT
Completed Not applicable Interventional Results available

AMBULATE Continued Access Protocol to Evaluate the Cardiva Mid-Bore Venous Vascular Closure System (VVCS)

NCT03573206
View directory record Official record
Conditions
Surgical Wound
Interventions
Cardiva Mid-Bore Venous Vascular Closure Device (VVCS)
Device
Lead sponsor
Cardiva Medical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
168 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
3
States / cities
Atlanta, Georgia • Ridgewood, New Jersey • Austin, Texas
Source: ClinicalTrials.gov public record
Updated Mar 9, 2023 · Synced Jul 21, 2026, 4:40 PM EDT
Completed Not applicable Interventional Results available

An Evaluation of Rigid Sternal Fixation in Supporting Bone Healing and Improving Postoperative Recovery

NCT01783483
View directory record Official record
Conditions
Coronary Artery Disease, Angina Pectoris, Cardiac Valve Disease
Interventions
SternaLock Blue closure system, Suture Wire
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
18 Years and older
Enrollment
236 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
12
States / cities
Jacksonville, Florida • Orlando, Florida • Atlanta, Georgia + 8 more
Source: ClinicalTrials.gov public record
Updated Sep 7, 2017 · Synced Jul 21, 2026, 4:40 PM EDT
Terminated Not applicable Interventional Results available

RFS (Radiofrequency Stylet) - Radiofrequency Perforator Vein Treatment Study

NCT01079598
View directory record Official record
Conditions
Venous Insufficiency
Interventions
RF Ablation (ClosureRFS Stylet)
Device
Lead sponsor
Medtronic Endovascular
Industry
Eligibility
18 Years to 80 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
3
States / cities
Birmingham, Alabama • Evans, Georgia • Jackson, Michigan
Source: ClinicalTrials.gov public record
Updated May 4, 2017 · Synced Jul 21, 2026, 4:40 PM EDT