Independent directory Public ClinicalTrials.gov records United States
Clinical Trials Finder
Objective public record navigation
Search Results

Search by objective public record fields.

Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results are retrieved from ClinicalTrials.gov and synchronized into the directory. Search pages remain noindex by default.

Clear filters
ClinicalTrials.gov public records Last synced Jun 9, 2026, 11:49 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 53 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Condition: Vasopressor Clear all
Recruiting Phase 4 Interventional

Early Versus Late Adjunctive Vasopressin in Septic Shock

NCT06709573
View directory record Official record
Conditions
Sepsis, Septic Shock
Interventions
vasopressin - early initiation, vasopressin - standard initiation
Drug
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 11, 2026 · Synced Jun 9, 2026, 11:49 PM EDT
Not listed No phase listed Observational

Study of Treatment's Echocardiographic Mechanisms

NCT03913403
View directory record Official record
Conditions
Sepsis
Interventions
ECHO, Blood Draw
Procedure
Lead sponsor
Intermountain Health Care, Inc.
Other
Eligibility
18 Years and older
Enrollment
210 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
7
States / cities
Boston, Massachusetts • The Bronx, New York • Winston-Salem, North Carolina + 4 more
Source: ClinicalTrials.gov public record
Updated Feb 9, 2021 · Synced Jun 9, 2026, 11:49 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Behavioral Effects of Drugs (Inpatient): 40 [Methamphetamine, Methylphenidate, Duloxetine]

NCT04178993
View directory record Official record
Conditions
Methamphetamine Use Disorder
Interventions
Methamphetamine, Methylphenidate, Placebo oral capsule, Duloxetine
Drug
Lead sponsor
Craig Rush
Other
Eligibility
18 Years to 55 Years
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
2
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Jan 8, 2023 · Synced Jun 9, 2026, 11:49 PM EDT
Terminated Phase 2Phase 3 Interventional Results available

Selepressin Evaluation Programme for Sepsis-Induced Shock - Adaptive Clinical Trial

NCT02508649
View directory record Official record
Conditions
Septic Shock
Interventions
selepressin, placebo
Drug
Lead sponsor
Ferring Pharmaceuticals
Industry
Eligibility
18 Years and older
Enrollment
868 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
17
States / cities
Colorado Springs, Colorado • Idaho Falls, Idaho • Chicago, Illinois + 13 more
Source: ClinicalTrials.gov public record
Updated Apr 5, 2021 · Synced Jun 9, 2026, 11:49 PM EDT
Terminated Phase 2 Interventional Results available

Vitamin B12a Vasoplegic Syndrome

NCT03735316
View directory record Official record
Conditions
Vasoplegic Syndrome
Interventions
Hydroxocobalamin, Cardiopulmonary Bypass, Placebos
Drug · Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated May 9, 2023 · Synced Jun 9, 2026, 11:49 PM EDT
Terminated Not applicable Interventional Results available

Treatment of Vasopressor-induced Ischemia With Botulinum Toxin A

NCT01483209
View directory record Official record
Conditions
Ischemia, Vasopressor
Interventions
Injection of botulinum toxin A
Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 1, 2015 · Synced Jun 9, 2026, 11:49 PM EDT
Completed Phase 3 Interventional Results available

Midodrine for the Treatment of Refractory Hypotension

NCT01531959
View directory record Official record
Conditions
Hypotension, Critical Illness
Interventions
Midodrine, Placebo
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
139 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2019
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 27, 2020 · Synced Jun 9, 2026, 11:49 PM EDT
Terminated Phase 3 Interventional Accepts healthy volunteers Results available

Midodrine Use in Septic Shock

NCT03706053
View directory record Official record
Conditions
Septic Shock
Interventions
Midodrine Hydrochloride, placebo
Drug · Other
Lead sponsor
University of Virginia
Other
Eligibility
18 Years to 89 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Sep 23, 2025 · Synced Jun 9, 2026, 11:49 PM EDT
Completed Not applicable Interventional Results available

A Prospective Study Evaluating the Use of Intraoperative Stroke Volume Variation Via the FloTrac Device to Guide Fluid and Vasopressor Management in Head and Neck Free Flaps

NCT02186938
View directory record Official record
Conditions
Head and Neck Cancer, Patients Requiring a Free Flap Surgery
Interventions
FloTrac
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
94 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Sep 19, 2018 · Synced Jun 9, 2026, 11:49 PM EDT
Not listed No phase listed Observational

Effectiveness of Blood Clot Medication With Concomitant Blood Pressure Medication

NCT00424281
View directory record Official record
Conditions
ICU Patients 18 Years or Older.
Interventions
Arixtra (fondaparinux), 2.5 mg/day-what is bioavailability
Drug
Lead sponsor
Wayne State University
Other
Eligibility
18 Years to 80 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Jan 18, 2007 · Synced Jun 9, 2026, 11:49 PM EDT
Completed No phase listed Observational Results available

Evaluating the Effect of Chronic Antihypertensive Therapy on Vasopressor Dosing in Septic Shock

NCT02884011
View directory record Official record
Conditions
Septic Shock
Interventions
Not listed
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years and older
Enrollment
133 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 2, 2025 · Synced Jun 9, 2026, 11:49 PM EDT
Completed Phase 4 Interventional Results available

Norepinephrine vs Phenylephrine During General Anesthesia

NCT04789330
View directory record Official record
Conditions
Anesthesia, Surgery, Hypotension
Interventions
Norepinephrine, Phenylephrine
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 99 Years
Enrollment
3,626 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
5
States / cities
Los Angeles, California • San Francisco, California
Source: ClinicalTrials.gov public record
Updated Dec 17, 2025 · Synced Jun 9, 2026, 11:49 PM EDT
Terminated Phase 1 Interventional

Exploratory Study of Norepinephrine to Prevent Alopecia in Head and Neck Cancer Patients Treated With Radiotherapy

NCT01367990
View directory record Official record
Conditions
Alopecia, Radiodermatitis
Interventions
Norepinephrine
Drug
Lead sponsor
ProCertus BioPharm, Inc
Industry
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Mar 22, 2012 · Synced Jun 9, 2026, 11:49 PM EDT
Completed Phase 1 Interventional Results available

Intravenous AII for the Treatment of Severe Hypotension in High Output Shock: A Pilot Study

NCT01393782
View directory record Official record
Conditions
Septic Shock
Interventions
Angiotensin II
Drug
Lead sponsor
George Washington University
Other
Eligibility
21 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Apr 11, 2024 · Synced Jun 9, 2026, 11:49 PM EDT
Completed Phase 4 Interventional Results available

Renin and Renal Biomarker Response to Angiotensin II

NCT04558359
View directory record Official record
Conditions
Septic Shock, Acute Kidney Injury
Interventions
Standard of Care, Angiotensin II
Other · Drug
Lead sponsor
Alexander Flannery
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Sep 3, 2024 · Synced Jun 9, 2026, 11:49 PM EDT
Completed Not applicable Interventional

Pragmatic Randomized Trial for Arterial Catheters in the Critical Care Environment

NCT05411315
View directory record Official record
Conditions
Mechanical Ventilation Complication, Arterial Thrombosis, Limb Ischemia, Shock, Hypotension, Bloodstream Infection, Vasopressor Adverse Reaction, Renal Failure
Interventions
Restricted-use of arterial catheter, Standard-use of arterial catheter
Other
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years and older
Enrollment
700 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Feb 25, 2024 · Synced Jun 9, 2026, 11:49 PM EDT
Completed Phase 3 Interventional

Using Vasopressor Medication to Support Blood Pressure During Intubation Procedure

NCT05355974
View directory record Official record
Conditions
Respiratory Failure, Hypotension and Shock, Hypotension on Induction, Intubation Complication, Anesthesia Intubation Complication
Interventions
Norepinephrine, Lactated Ringers, Intravenous, normal saline, Plasma-lyte
Drug
Lead sponsor
Wright State University
Other
Eligibility
18 Years and older
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Dayton, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 14, 2024 · Synced Jun 9, 2026, 11:49 PM EDT
Recruiting Phase 4 Interventional

The Choice of Vasopressor to Prevent Postoperative Acute Kidney Injury After Major Non-Cardiac Surgery

NCT06802224
View directory record Official record
Conditions
Anesthesia, Surgery With General Anesthesia, Noncardiac Surgery, Hypotension During Surgery, Acute Kidney Injury (AKI), Myocardial Injury After Noncardiac Surgery (MINS), Vasopressor
Interventions
Norepinephrine, Phenylephrine
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
18,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
9
States / cities
San Francisco, California • College Park, Maryland • Ann Arbor, Michigan + 6 more
Source: ClinicalTrials.gov public record
Updated May 25, 2026 · Synced Jun 9, 2026, 11:49 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Study to Evaluate if the Drug Vasopressin Protects the Kidneys for Patients Undergoing Liver Transplant

NCT00886262
View directory record Official record
Conditions
Liver Failure
Interventions
Vasopressin, Normal saline placebo
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 80 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2011
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Oct 16, 2018 · Synced Jun 9, 2026, 11:49 PM EDT
Active, not recruiting Phase 4 Interventional

Vasopressin for Septic Shock Pragmatic Trial

NCT06217562
View directory record Official record
Conditions
Septic Shock
Interventions
Vasopressin, Recommendation to use a lower initiation threshold for vasopressin, Recommendation to use a higher initiation threshold for vasopressin
Drug · Other
Lead sponsor
Intermountain Health Care, Inc.
Other
Eligibility
18 Years and older
Enrollment
2,050 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
13
States / cities
Burley, Idaho • American Fork, Utah • Cedar City, Utah + 10 more
Source: ClinicalTrials.gov public record
Updated Oct 20, 2025 · Synced Jun 9, 2026, 11:49 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Randomized, Double-Blind, Trial Comparing Epinephrine Versus Phenylephrine as a Vasoconstrictor in Regional Anesthesia for Upper Extremity Surgery

NCT00225043
View directory record Official record
Conditions
Healthy
Interventions
Epinephrine/phenylephrine
Drug
Lead sponsor
New York Presbyterian Brooklyn Methodist Hospital
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2007
U.S. locations
1
States / cities
Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Jun 1, 2008 · Synced Jun 9, 2026, 11:49 PM EDT
Completed Phase 2 Interventional

A Study of LJPC-501 in Pediatric Patients With Hypotension

NCT03431077
View directory record Official record
Conditions
Catecholamine-resistant Hypotension (CRH), Distributive Shock, High Output Shock, Sepsis
Interventions
Angiotensin II
Drug
Lead sponsor
La Jolla Pharmaceutical Company
Industry
Eligibility
2 Years to 17 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
3
States / cities
Charlotte, North Carolina • Cincinnati, Ohio • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Aug 6, 2018 · Synced Jun 9, 2026, 11:49 PM EDT
Enrolling by invitation Phase 4 Interventional

The GUARDIAN Trial - Vasopressor Sub-Study

NCT04934748
View directory record Official record
Conditions
Blood Pressure
Interventions
Routine Blood Pressure Management, Tight Blood Pressure Management, Phenylephrine, Norepinephrine
Procedure · Drug
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
45 Years and older
Enrollment
6,254 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
4
States / cities
Omaha, Nebraska • Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 28, 2025 · Synced Jun 9, 2026, 11:49 PM EDT
Completed No phase listed Observational

Time to Lose the Weight? Comparison of Weight-based and Non-weight-based Vasopressors for Septic Shock

NCT04153578
View directory record Official record
Conditions
Septic Shock, Weight, Body
Interventions
Not listed
Lead sponsor
Methodist Health System
Other
Eligibility
18 Years and older
Enrollment
945 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Mar 26, 2026 · Synced Jun 9, 2026, 11:49 PM EDT