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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Completed No phase listed Observational Accepts healthy volunteers

Short Term Outcomes of Heavy-weight Versus Medium-weight Synthetic Mesh

NCT06409091
Conditions
Hernia, Ventral, Hernia Incisional
Interventions
Medium weight or Heavy weight mesh
Device
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
1,496 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2023
U.S. locations
1
States / cities
Cleveland, Ohio
Conditions
Hernia, Obesity
Interventions
Surgisis Gold Graft, Control
Device · Procedure
Lead sponsor
Cook Group Incorporated
Industry
Eligibility
18 Years and older
Enrollment
402 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2012
U.S. locations
2
States / cities
Rochester, Minnesota • Richmond, Virginia
Conditions
Frailty, Ventral Hernia
Interventions
Prehabilitation, Standard of Care (SOC)
Behavioral · Other
Lead sponsor
Prisma Health-Upstate
Other
Eligibility
65 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Greenville, South Carolina
Conditions
Ventral Hernia
Interventions
MaxTack™ Motorized Fixation Device
Device
Lead sponsor
Medtronic - MITG
Industry
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
3
States / cities
Weston, Florida • Cleveland, Ohio • Columbus, Ohio
Conditions
Ventral Hernia Repair
Interventions
Silk surgical mesh
Device
Lead sponsor
Sofregen Medical, Inc.
Industry
Eligibility
18 Years to 70 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Lexington, Kentucky
Conditions
Hernia, Inguinal, Hernia, Ventral
Interventions
AbsorbaTack, ProTack
Device
Lead sponsor
Medtronic - MITG
Industry
Eligibility
18 Years and older
Enrollment
216 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
2
States / cities
Cleveland, Ohio • Greenville, South Carolina
Completed Not applicable Interventional Results available

Ventral Hernia Study Using OviTex Reinforced Bioscaffold

NCT03074474
Conditions
Hernia, Ventral
Interventions
OviTex 1S Permanent
Device
Lead sponsor
Tela Bio Inc
Industry
Eligibility
18 Years and older
Enrollment
92 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
7
States / cities
La Jolla, California • Sarasota, Florida • Indianapolis, Indiana + 4 more
Conditions
Ventral Hernia, Incisional Hernia
Interventions
Mesh placement with Transfascial Sutures
Procedure
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
325 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Cleveland, Ohio
Recruiting Not applicable Interventional

GORE® ENFORM Biomaterial Product Study

NCT04718168
Conditions
Hernia, Ventral, Hernia, Hiatal, Hernia, Diaphragmatic, Incisional Hernia
Interventions
Gore ENFORM Biomaterial (Preperitoneal), Gore ENFORM Biomaterial (Intraperitoneal)
Device
Lead sponsor
W.L.Gore & Associates
Industry
Eligibility
18 Years and older
Enrollment
245 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
9
States / cities
San Diego, California • Denver, Colorado • Sarasota, Florida + 6 more
Completed Not applicable Interventional Results available

Biologic Mesh Versus Synthetic Mesh in Repair of Ventral Hernias

NCT02451176
Conditions
Ventral Hernia
Interventions
Davol Bard Soft Mesh synthetic, LifeCell Strattice Reconstructive Tissue Biologic
Device
Lead sponsor
Michael Rosen
Other
Eligibility
21 Years and older
Enrollment
253 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2021
U.S. locations
4
States / cities
St Louis, Missouri • Cleveland, Ohio • Greenville, South Carolina + 1 more
Conditions
Ventral Hernia
Interventions
Opioid pain medication prescribed based on CYP2D6 genotype testing PLUS Acetaminophen and Gabapentin, Acetaminophen and Gabapentin: standard postoperative pain medications
Other
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 90 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Jacksonville, Florida
Conditions
Inguinal Hernia, Ventral Hernia
Interventions
Liposomal Bupivacaine, Bupivacaine
Drug
Lead sponsor
Leslie Son
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Recruiting Not applicable Interventional Accepts healthy volunteers

Robotic Versus Open Ventral Hernia Repair

NCT05472987
Conditions
Ventral Hernia
Interventions
Ventral Hernia Repair
Procedure
Lead sponsor
Lucas Beffa
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
4
States / cities
Gainesville, Florida • Cleveland, Ohio • Greenville, South Carolina + 1 more
Recruiting No phase listed Observational Accepts healthy volunteers

Cytokine Response to Abdominal Wall Reconstruction

NCT07422584
Conditions
Incisional Ventral Hernia
Interventions
Not applicable- observational study
Other
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Open Midline Laparotomy
Interventions
Phasix™ Mesh
Device
Lead sponsor
C. R. Bard
Industry
Eligibility
18 Years and older
Enrollment
477 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2031
U.S. locations
31
States / cities
Phoenix, Arizona • Los Angeles, California • San Francisco, California + 25 more
Completed Not applicable Interventional Accepts healthy volunteers

CT and Radiologist RCT

NCT03121131
Conditions
Hernia
Interventions
Clinical Exam Findings, Inaccurate Clinical Exam Findings, No clinical exam findings
Other
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
7 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Houston, Texas
Conditions
Ventral Hernia
Interventions
Not listed
Lead sponsor
AdventHealth
Other
Eligibility
18 Years to 89 Years
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Celebration, Florida
Completed Not applicable Interventional Accepts healthy volunteers Results available

Heavy Weight Versus Medium Weight Mesh in Ventral Hernia Repair

NCT03082391
Conditions
Ventral Hernia
Interventions
Heavy weight Mesh, Medium weight Mesh
Device
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 90 Years
Enrollment
350 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Cleveland, Ohio
Conditions
Postoperative Pain
Interventions
Bupivicaine Infusion
Drug
Lead sponsor
Chang, Steve S., M.D.
Individual
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Santa Barbara, California
Completed Not applicable Interventional Results available

Analgesic Efficacy After Umbilical Hernia Repair in Children

NCT00578136
Conditions
Umbilical Hernia
Interventions
Bupivacaine
Drug
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
5 Years to 17 Years
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2011
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Completed No phase listed Observational Results available

T-GENVIH-003 LTFU (Long Term Follow Up) Study

NCT06034652
Conditions
Hernia, Hernia, Ventral, Pathological Conditions, Anatomical, Hernia, Abdominal
Interventions
Integra® Gentrix® Surgical Matrix
Device
Lead sponsor
Integra LifeSciences Corporation
Industry
Eligibility
22 Years to 80 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Fort Myers, Florida
Completed Not applicable Interventional Accepts healthy volunteers

Video-based Collaborative Learning to Improve Ventral Hernia Repair

NCT04173884
Conditions
Ventral Hernia
Interventions
Coaching, Constructive Feedback
Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
21 Years and older
Enrollment
59 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2025
U.S. locations
1
States / cities
Madison, Wisconsin
Conditions
Ventral Hernia
Interventions
Alvimopan, Placebo
Drug
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Conditions
Hernia, Ventral, Hernia Incisional, Hernia Incisional Ventral
Interventions
Hernia repair with mesh
Device
Lead sponsor
W.L.Gore & Associates
Industry
Eligibility
18 Years to 80 Years
Enrollment
320 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2030
U.S. locations
8
States / cities
Atlanta, Georgia • Boston, Massachusetts • Grand Rapids, Michigan + 5 more