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Showing 1–24 of 38 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Ventricular Function, Right Clear all
Enrolling by invitation Not applicable Interventional

Effect of PEEP on Cardiac Function

NCT07531602
View directory record Official record
Conditions
Cardiac Surgery Subjects
Interventions
EIT Guided PEEP Trial
Procedure
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 30, 2026 · Synced Sep 5, 2026, 2:30 PM EDT
Completed No phase listed Observational

Short-term Clinical Deterioration After Acute Pulmonary Embolism

NCT03915925
View directory record Official record
Conditions
Pulmonary Embolism
Interventions
Not listed
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
935 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
6
States / cities
San Diego, California • Newark, Delaware • Orlando, Florida + 3 more
Source: ClinicalTrials.gov public record
Updated Apr 26, 2022 · Synced Sep 5, 2026, 2:30 PM EDT
Completed Not applicable Interventional

Functional Outcomes in CondUction System Pacing and Right Ventricular Synchrony (FOCUS-Right)

NCT06601322
View directory record Official record
Conditions
Left Branch Bundle Block, RV - Right Ventricular Abnormality
Interventions
Pacemaker Interrogation and Electrocardiogram (ECG):, Cardiopulmonary Exercise Test (CPET) and Exercise Stress Cardiac Magnetic Resonance (ExeCMR, Continuous pacemaker telemetry (CPT)
Other
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 11, 2026 · Synced Sep 5, 2026, 2:30 PM EDT
Suspended Not applicable Interventional

Exercise Training to Improve Cardiopulmonary Hemodynamics in Heart Failure Patients

NCT04909008
View directory record Official record
Conditions
Heart Failure, Pulmonary Hypertension
Interventions
Exercise Training
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated May 3, 2026 · Synced Sep 5, 2026, 2:30 PM EDT
Completed Not applicable Interventional

"Reversibility of Cardiovascular Injury With CPAP Use: Mechanisms Involved"

NCT01317329
View directory record Official record
Conditions
Sleep Apnea, Obstructive, Hypoxia, Hypercapnia, Sleep Disorders, Obesity, Hypertension, Coronary Artery Vasospasm, Right Ventricular Overload, Left Ventricular Function Systolic Dysfunction, Ventricular Hypertrophy
Interventions
Clinically prescribed CPAP therapy
Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
21 Years to 50 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Mar 5, 2020 · Synced Sep 5, 2026, 2:30 PM EDT
Recruiting Not applicable Interventional

Feasibility of the SCD in Cardiorenal Syndrome Patients Awaiting LVAD

NCT03836482
View directory record Official record
Conditions
Acute on Chronic Systolic Congestive Heart Failure, Cardiorenal Syndrome
Interventions
Selective Cytopheretic Device
Device
Lead sponsor
SeaStar Medical
Industry
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 30, 2026 · Synced Sep 5, 2026, 2:30 PM EDT
Completed No phase listed Observational

Validating TEE Measurements of Right Ventricular Function

NCT03264183
View directory record Official record
Conditions
Ventricular Function, Right, Echocardiography, Transesophageal
Interventions
Transesophageal Echocardiography, Transthoracic Echocardiography
Diagnostic Test
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years and older
Enrollment
126 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 23, 2019 · Synced Sep 5, 2026, 2:30 PM EDT
Completed Phase 4 Interventional Results available

Targeting the Right Ventricle in Pulmonary Hypertension

NCT01839110
View directory record Official record
Conditions
Pulmonary Hypertension
Interventions
Ranolazine, Placebo
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 80 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
3
States / cities
Baltimore, Maryland • Boston, Massachusetts • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 4, 2019 · Synced Sep 5, 2026, 2:30 PM EDT
Completed No phase listed Observational

Speckle-tracking Tricuspid Annular Plane Systolic Excursion

NCT01968252
View directory record Official record
Conditions
Ventricular Function, Right
Interventions
Concurrent TTE and TEE
Other
Lead sponsor
University of Nebraska
Other
Eligibility
19 Years to 90 Years
Enrollment
112 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Aug 31, 2023 · Synced Sep 5, 2026, 2:30 PM EDT
Completed No phase listed Observational

MRI Assessment of RV Function: Patients With TOF or Aortic Coarctation

NCT00277901
View directory record Official record
Conditions
Congenital Disorders
Interventions
Not listed
Lead sponsor
Children's Healthcare of Atlanta
Other
Eligibility
Up to 21 Years
Enrollment
390 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2009
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Dec 1, 2014 · Synced Sep 5, 2026, 2:30 PM EDT
Completed No phase listed Observational

Dysregulation of Lipid Metabolism and Right Ventricular Function in PAH

NCT02631421
View directory record Official record
Conditions
Pulmonary Arterial Hypertension
Interventions
Blood Sampling, Cardiac MRI
Procedure · Other
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jul 15, 2019 · Synced Sep 5, 2026, 2:30 PM EDT
Completed Not applicable Interventional

Assessment of Right Ventricular Volume in Pediatric Patients

NCT04099810
View directory record Official record
Conditions
Ventricular Function
Interventions
three-dimensional echocardiography
Diagnostic Test
Lead sponsor
Boston Children's Hospital
Other
Eligibility
Up to 18 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 3, 2026 · Synced Sep 5, 2026, 2:30 PM EDT
Completed Early Phase 1 Interventional

Dynamic Assessment of Right Ventricular Function With Inhaled Nitric Oxide During Cardiac MRI

NCT02220023
View directory record Official record
Conditions
Pulmonary Vascular Disorder
Interventions
INOmax Inhalation
Drug
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Feb 12, 2017 · Synced Sep 5, 2026, 2:30 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Right Ventricular Metabolism in Pulmonary Arterial Hypertension

NCT02763735
View directory record Official record
Conditions
Pulmonary Arterial Hypertension, Healthy
Interventions
Not listed
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2019
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated May 19, 2020 · Synced Sep 5, 2026, 2:30 PM EDT
Completed Phase 2 Interventional Results available

Improving Right Ventricular Function in Young Adults Born Preterm

NCT03696758
View directory record Official record
Conditions
Infant,Premature
Interventions
Pulmonary Function Testing, Electrocardiogram, Cardiac Magnetic Resonance Imaging, Metoprolol, Sildenafil
Procedure · Drug
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 35 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Mar 16, 2021 · Synced Sep 5, 2026, 2:30 PM EDT
Recruiting Phase 2 Interventional

Empagliflozin to Improve Right Ventricular Function in Pulmonary Arterial Hypertension

NCT06992440
View directory record Official record
Conditions
Pulmonary Arterial Hypertension
Interventions
Empagliflozin 10 MG, Placebo
Drug
Lead sponsor
Gustavo A Heresi, MD, MS
Other
Eligibility
18 Years and older
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
3
States / cities
Baltimore, Maryland • Cleveland, Ohio • Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Aug 12, 2026 · Synced Sep 5, 2026, 2:30 PM EDT
Terminated Not applicable Interventional

Open Lung Strategy, Gas Distribution and Right Heart Function in ARDS Patients

NCT03202641
View directory record Official record
Conditions
ARDS, Human, Lung Injury, Acute, Respiratory Distress Syndrome, Mechanical Ventilation Complication, Alveolar Edema, Right Heart Failure, Right Ventricular Dysfunction
Interventions
PEEP ARDSnet, PEEP LRM
Procedure
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 85 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 18, 2025 · Synced Sep 5, 2026, 2:30 PM EDT
Completed No phase listed Observational Results available

TEE 3D RV Assessment for SAVR, Mini AVR, and TAVR

NCT05804240
View directory record Official record
Conditions
Right Ventricular Dysfunction
Interventions
3D TEE RVEF
Diagnostic Test
Lead sponsor
Thomas Jefferson University
Other
Eligibility
18 Years and older
Enrollment
67 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 12, 2026 · Synced Sep 5, 2026, 2:30 PM EDT
Completed Not applicable Interventional

Effects of Changes in Fluid Status on Right Ventricular Volumes and Function

NCT02967315
View directory record Official record
Conditions
Tetralogy of Fallot
Interventions
Cardiac Magnetic Resonance Imaging (CMRI), Central venous line placement, Chest X-ray, Fluid administration, Blood Draw, Pregnancy test, Electrocardiogram
Procedure
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2021
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Apr 13, 2021 · Synced Sep 5, 2026, 2:30 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Natural History Study of Biomarkers in Pulmonary Arterial Hypertension

NCT01730092
View directory record Official record
Conditions
Pulmonary Disease, Pulmonary Hypertension
Interventions
Not listed
Lead sponsor
National Institutes of Health Clinical Center (CC)
NIH
Eligibility
18 Years to 100 Years
Enrollment
270 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2013
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 17, 2026 · Synced Sep 5, 2026, 2:30 PM EDT
Withdrawn Not applicable Interventional

Impact of Cardiac Resynchronization Therapy on Right Ventricular Function in Left Ventricular Assist Device Patients

NCT02169076
View directory record Official record
Conditions
Heart Failure
Interventions
Cardiac Resynchronization Therapy
Device
Lead sponsor
University of Louisville
Other
Eligibility
18 Years to 80 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Jan 4, 2017 · Synced Sep 5, 2026, 2:30 PM EDT
Not yet recruiting Early Phase 1 Interventional Accepts healthy volunteers

Impact of Iron Supplementation on Right Ventricular Function and Exercise Performance in Hypoxia

NCT05349630
View directory record Official record
Conditions
Right Ventricular Dysfunction, Hypoxia
Interventions
Ferrous sulfate 325mg
Drug
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 60 Years
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2028 – 2030
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Apr 28, 2026 · Synced Sep 5, 2026, 2:30 PM EDT
Not listed No phase listed Observational

Cardiopulmonary and Right Ventricular Function in Health and Disease

NCT04147299
View directory record Official record
Conditions
Heart Failure, Athletes Heart
Interventions
Not listed
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 89 Years
Enrollment
80 participants
Timeline
2020 – 2025
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated May 17, 2023 · Synced Sep 5, 2026, 2:30 PM EDT
Not yet recruiting Phase 1Phase 2 Interventional

Neuromodulation in Patients With Pulmonary Arterial Hypertension

NCT06802380
View directory record Official record
Conditions
Pulmonary Hypertension
Interventions
Low-level tragus stimulation, Sham stimulation
Device
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years to 90 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Aug 26, 2025 · Synced Sep 5, 2026, 2:30 PM EDT