- Conditions
- Walking Impairment, Multiple Sclerosis
- Interventions
- ADS-5102, 137 mg, ADS-5102, 274 mg, Placebo
- Drug · Other
- Lead sponsor
- Adamas Pharmaceuticals, Inc.
- Industry
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 558 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2019
- U.S. locations
- 78
- States / cities
- Cullman, Alabama • Phoenix, Arizona • Scottsdale, Arizona + 73 more
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- Conditions
- Multiple Sclerosis, Walking Impairment
- Interventions
- ADS-5102, 274 mg
- Drug
- Lead sponsor
- Adamas Pharmaceuticals, Inc.
- Industry
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 424 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2021
- U.S. locations
- 82
- States / cities
- Cullman, Alabama • Phoenix, Arizona • Tucson, Arizona + 75 more
- Conditions
- Stroke
- Interventions
- Not listed
- Lead sponsor
- Shirley Ryan AbilityLab
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 80 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2025 – 2027
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Heart Failure, Cardiac Failure, Congestive Heart Failure, Insomnia, Sleep Disorder, Sleep Initiation and Maintenance Disorders, Disorders of Initiating and Maintaining Sleep, Anxiety, Depression
- Interventions
- Brief treatment for Insomnia, Sleep Monitoring
- Behavioral
- Lead sponsor
- Ohio State University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 76 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2023
- U.S. locations
- 1
- States / cities
- Columbus, Ohio
- Conditions
- Respiratory Impairment, Elevated Blood Pressure, Physical Inactivity
- Interventions
- Increased lifestyle walking (intervention), Health education only (control)
- Other
- Lead sponsor
- Iowa State University
- Other
- Eligibility
- 65 Years and older
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2024
- U.S. locations
- 1
- States / cities
- Ames, Iowa
- Conditions
- Walking Impairment, Multiple Sclerosis
- Interventions
- ADS-5102, Placebo
- Drug · Other
- Lead sponsor
- Adamas Pharmaceuticals, Inc.
- Industry
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2016
- U.S. locations
- 15
- States / cities
- Phoenix, Arizona • Aurora, Colorado • Sarasota, Florida + 12 more
- Conditions
- Stroke, Gait Impairment
- Interventions
- Active transcranial Direct Current Stimulation, Sham transcranial Direct Current Stimulation
- Other
- Lead sponsor
- VA Office of Research and Development
- Federal
- Eligibility
- 18 Years and older
- Enrollment
- 44 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2024
- U.S. locations
- 1
- States / cities
- Cleveland, Ohio
- Conditions
- Caregiver Burden, Depression, Cognitive Impairment
- Interventions
- SHARP - Physical and social activity
- Behavioral
- Lead sponsor
- Oregon Health and Science University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 21 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2023 – 2024
- U.S. locations
- 1
- States / cities
- Portland, Oregon
- Conditions
- Older Adults, Multiple Sclerosis, Cognitive Impairment, Walking Impairment
- Interventions
- Aerobic and Resistance Exercise Program (GEMS program), Flexibility and Stretching Program (FLEX-MS program)
- Behavioral
- Lead sponsor
- University of Illinois at Chicago
- Other
- Eligibility
- 50 Years and older
- Enrollment
- 51 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2025
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Multiple Sclerosis
- Interventions
- Lokomat, resistive training
- Device · Procedure
- Lead sponsor
- University of California, Los Angeles
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 38 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2009
- U.S. locations
- 1
- States / cities
- Los Angeles, California
- Conditions
- Infrainguinal Peripheral Artery Disease, Peripheral Arterial Disease, PAD
- Interventions
- AURYON Atherectomy System
- Device
- Lead sponsor
- Angiodynamics, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 102 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2023
- U.S. locations
- 10
- States / cities
- Scottsdale, Arizona • Tucson, Arizona • Davenport, Florida + 7 more
- Conditions
- Anxiety, Trauma, Hospitalized Adult Patients, Rehabilitation, Physical Mobility Impairment, Therapy Dog
- Interventions
- Therapy Dog, Standard mobilization
- Other
- Lead sponsor
- Andrew Bernard
- Other
- Eligibility
- 18 Years to 99 Years
- Enrollment
- 64 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025
- U.S. locations
- 1
- States / cities
- Lexington, Kentucky
- Conditions
- Stroke, Depression - Major Depressive Disorder, Walking Impairment
- Interventions
- rTMS, AEx
- Device · Behavioral
- Lead sponsor
- Medical University of South Carolina
- Other
- Eligibility
- 21 Years to 70 Years
- Enrollment
- 96 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2029
- U.S. locations
- 2
- States / cities
- Durham, North Carolina • Charleston, South Carolina
- Conditions
- Multiple Sclerosis, Physical Activity, Memory Impairment, Cognitive Change
- Interventions
- Treadmill Walking Exercise Training, Stretching-and-toning Exercise Training
- Behavioral
- Lead sponsor
- University of Alabama at Birmingham
- Other
- Eligibility
- 18 Years to 54 Years
- Enrollment
- 14 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2021
- U.S. locations
- 1
- States / cities
- Birmingham, Alabama
- Conditions
- Chronic Pain, Physical Activity, Older Adults, Mild Cognitive Impairment
- Interventions
- MBCT+w, ALED
- Behavioral
- Lead sponsor
- Massachusetts General Hospital
- Other
- Eligibility
- 50 Years and older
- Enrollment
- 400 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2028
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Lumbar Spinal Stenosis
- Interventions
- opana then darvocet then placebo, opana then placebo then darvocet, placebo then opana then darvocet, Placebo then darvocet then opana, Darvocet then opana then placebo, Darvocet then placebo then opana
- Drug
- Lead sponsor
- University of Rochester
- Other
- Eligibility
- 50 Years and older
- Enrollment
- 24 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2011
- U.S. locations
- 1
- States / cities
- Rochester, New York