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ClinicalTrials.gov public records Last synced Oct 20, 2026, 5:30 AM EDT

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Showing 313–336 of 1,735 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Weight Loss Clear all
Completed Not applicable Interventional

Smart Technology for Weight Loss and Metabolic Health

NCT02742662
View directory record Official record
Conditions
Obesity, Overweight, Prediabetes, Weight Loss, Lifestyle
Interventions
Wearable technology, smartscale, Smartphone applications, Standard Weight Management Visits
Device · Behavioral
Lead sponsor
Temple University
Other
Eligibility
18 Years to 65 Years
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 15, 2018 · Synced Oct 20, 2026, 5:30 AM EDT
Recruiting Not applicable Interventional

Planning Grant for TOPS for Breast Cancer Survivors

NCT06658912
View directory record Official record
Conditions
Breast Cancer, Weight Loss
Interventions
TOPS Classes
Other
Lead sponsor
Duke University
Other
Eligibility
21 Years to 90 Years · Female only
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 5, 2026 · Synced Oct 20, 2026, 5:30 AM EDT
Withdrawn Not applicable Interventional

Families, Responsibility, Education, Support, and Health for Executive Function

NCT05165511
View directory record Official record
Conditions
Overweight and Obesity, Attention-Deficit Hyperactivity Disorder
Interventions
PBT-EF
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
8 Years to 12 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Mar 4, 2026 · Synced Oct 20, 2026, 5:30 AM EDT
Completed Phase 2Phase 3 Interventional

Effects of Intentional Weight Loss Interventions in Chronic Kidney Disease

NCT01180101
View directory record Official record
Conditions
Chronic Kidney Disease, Obesity
Interventions
Diet and exercise, Bariatric Surgery
Behavioral · Procedure
Lead sponsor
The Cleveland Clinic
Other
Eligibility
19 Years to 99 Years
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 27, 2016 · Synced Oct 20, 2026, 5:30 AM EDT
Completed Phase 2 Interventional Results available

A Study of LY3305677 Compared With Placebo in Adult Participants With Obesity or Overweight

NCT06124807
View directory record Official record
Conditions
Obesity, Overweight and Obesity
Interventions
Mazdutide, Placebo
Drug
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
18 Years to 75 Years
Enrollment
179 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
29
States / cities
Chandler, Arizona • Scottsdale, Arizona • Tucson, Arizona + 25 more
Source: ClinicalTrials.gov public record
Updated Apr 21, 2026 · Synced Oct 20, 2026, 5:30 AM EDT
Completed Phase 4 Interventional Results available

Aromatase Inhibitors and Weight Loss in Severely Obese Hypogonadal Male Veterans (Pilot)

NCT02959853
View directory record Official record
Conditions
Hypogonadism, Severe Obesity
Interventions
Anastrazole, weight loss
Drug · Behavioral
Lead sponsor
Baylor College of Medicine
Other
Eligibility
35 Years to 65 Years · Male only
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 30, 2020 · Synced Oct 20, 2026, 5:30 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of Leptin A-200, Caffeine/Ephedrine and Their Combination Upon Weight Loss and Body Composition in Man

NCT01710722
View directory record Official record
Conditions
Obesity
Interventions
caffeine and ephedrine, Leptin A, caffeine, ephedrine, and leptin A
Drug
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
18 Years to 60 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2001 – 2002
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Dec 18, 2015 · Synced Oct 20, 2026, 5:30 AM EDT
Completed Not applicable Interventional

Lifestyle Changes Through Exercise and Nutrition

NCT02863887
View directory record Official record
Conditions
Obesity, Diabetes
Interventions
Weight loss intervention
Behavioral
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
18 Years to 75 Years
Enrollment
97 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Jun 6, 2018 · Synced Oct 20, 2026, 5:30 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

An Internet-based Weight Loss and Exercise Intervention for Breast Cancer Survivors

NCT01728506
View directory record Official record
Conditions
Breast Cancer
Interventions
Weight Loss and Exercise
Behavioral
Lead sponsor
University of Vermont
Other
Eligibility
21 Years to 69 Years · Female only
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
3
States / cities
Worcester, Massachusetts • Hannover, New Hampshire • Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated May 18, 2015 · Synced Oct 20, 2026, 5:30 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Preventing Obesity in Military Communities-Adolescents

NCT02671292
View directory record Official record
Conditions
Obesity, Overweight, Binge Eating
Interventions
Interpersonal Psychotherapy, Health Education
Behavioral · Other
Lead sponsor
Henry M. Jackson Foundation for the Advancement of Military Medicine
Other
Eligibility
12 Years to 17 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2021
U.S. locations
2
States / cities
Bethesda, Maryland • Fort Belvoir, Virginia
Source: ClinicalTrials.gov public record
Updated Feb 26, 2019 · Synced Oct 20, 2026, 5:30 AM EDT
Not listed Not applicable Interventional

The ReNEW Study: Maestro® New Enrollment Post-Approval Study Protocol

NCT03145636
View directory record Official record
Conditions
Obesity, Morbid
Interventions
vBloc Maestro Rechargeable System, vBloc Achieve Weight Management Program, Control Weight Management (CWM) program
Device · Other
Lead sponsor
ReShape Lifesciences
Industry
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2024
U.S. locations
2
States / cities
Scottsdale, Arizona • Mineola, New York
Source: ClinicalTrials.gov public record
Updated May 22, 2019 · Synced Oct 20, 2026, 5:30 AM EDT
Completed Not applicable Interventional Results available

Promoting Successful Weight Loss in Primary Care in Louisiana

NCT02561221
View directory record Official record
Conditions
Obesity
Interventions
Lifestyle Counseling
Behavioral
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
20 Years to 75 Years
Enrollment
803 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Aug 1, 2023 · Synced Oct 20, 2026, 5:30 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Role of High Intensity Interval Training in the Treatment of Adolescent Obesity

NCT03361644
View directory record Official record
Conditions
Pediatric Obesity, Adolescent Obesity, Weight Loss
Interventions
High-Intensity Interval Training, Moderate-Intensity Continuous Training
Behavioral
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
12 Years to 16 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Henrico, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 8, 2021 · Synced Oct 20, 2026, 5:30 AM EDT
Completed Phase 2 Interventional

A Study of Different Doses of Megestrol Acetate in Patients With AIDS Who Have Anorexia and Malnutrition

NCT00002300
View directory record Official record
Conditions
Anorexia, Cachexia, HIV Infections
Interventions
Megestrol acetate
Drug
Lead sponsor
Bristol-Myers Squibb
Industry
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
U.S. locations
15
States / cities
Birmingham, Alabama • Long Beach, California • Los Angeles, California + 9 more
Source: ClinicalTrials.gov public record
Updated Oct 2, 2007 · Synced Oct 20, 2026, 5:30 AM EDT
Completed No phase listed Observational

Gene x Behavior Interaction in the Look AHEAD Study

NCT01270763
View directory record Official record
Conditions
Obesity, Type 2 Diabetes
Interventions
Intensive lifestyle intervention, Diabetes support and education
Behavioral
Lead sponsor
The Miriam Hospital
Other
Eligibility
45 Years to 74 Years
Enrollment
4,108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2015
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Mar 18, 2015 · Synced Oct 20, 2026, 5:30 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Soy Protein and Colorado Diet on Weight Loss and Maintenance

NCT02380963
View directory record Official record
Conditions
Overweight, Obesity, Weight Loss
Interventions
Colorado Diet with soy protein foods., Colorado Diet with monetary payments
Dietary Supplement · Behavioral
Lead sponsor
DuPont Nutrition and Health
Industry
Eligibility
18 Years to 55 Years
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Oct 4, 2019 · Synced Oct 20, 2026, 5:30 AM EDT
Enrolling by invitation Not applicable Interventional

Testing a Multilevel, Culturally Appropriate Lifestyle Intervention For Hispanic Patients With Metabolic Dysfunction-associated Steatotic Liver Disease

NCT07199491
View directory record Official record
Conditions
Metabolic-dysfunction Associated Liver Disease (MASLD)
Interventions
Healthy Liver/Hígado Sano program, Usual Care
Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 3, 2026 · Synced Oct 20, 2026, 5:30 AM EDT
Active, not recruiting Not applicable Interventional

Evaluation of Bariatric Endoscopic Antral Myotomy (BEAM) as a Treatment for Obesity

NCT05713071
View directory record Official record
Conditions
Obesity, Weight Loss, Delayed Gastric Emptying Following Procedure, Obesity, Mild, Obesity, Morbid, Obesity; Excess Calories
Interventions
Bariatric Endoscopic Antral Myotomy
Procedure
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 70 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 25, 2026 · Synced Oct 20, 2026, 5:30 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Dietary Protein Intake From Beef/Pork and Soy/Legumes on Appetite, Mood, and Weight Loss

NCT01005563
View directory record Official record
Conditions
Appetite, Mood, Weight Loss
Interventions
Beef/Pork, Soy/Legumes
Other
Lead sponsor
Purdue University
Other
Eligibility
21 Years and older
Enrollment
37 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
2
States / cities
West Lafayette, Indiana
Source: ClinicalTrials.gov public record
Updated Mar 20, 2014 · Synced Oct 20, 2026, 5:30 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Virtual-reality Based Approach to Improve Behavioral Weight Management Outcomes

NCT04534088
View directory record Official record
Conditions
Weight Loss
Interventions
Standard Behavioral Weight Loss plus Non-Weight-Related VR app, Standard Behavioral Weight Loss plus Weight-Related VR app
Behavioral
Lead sponsor
California Polytechnic State University-San Luis Obispo
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
San Luis Obispo, California
Source: ClinicalTrials.gov public record
Updated Sep 24, 2020 · Synced Oct 20, 2026, 5:30 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Time-restricted Eating Versus Daily Continuous Calorie Restriction on Body Weight and Colorectal Cancer Risk Markers

NCT05114798
View directory record Official record
Conditions
Time Restricted Eating, Obesity, Weight Loss, Colorectal Cancer
Interventions
Time restricted eating, Calorie Restriction
Behavioral
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
45 Years to 70 Years
Enrollment
194 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 21, 2026 · Synced Oct 20, 2026, 5:30 AM EDT
Recruiting Not applicable Interventional

Snacking Effects on the Brain Response to Foods and Satiety During Dieting

NCT07428187
View directory record Official record
Conditions
Overweight/Obesity
Interventions
Snack Type 1: Walnuts, Snack Type 2: Pretzels
Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
25 Years to 45 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Mar 23, 2026 · Synced Oct 20, 2026, 5:30 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Grapefruit or Grapefruit Juice on Anthropometry, Dietary Intakes, Appetite, and Metabolic Profile in Overweight and Obese Young and Middle-Aged Adults

NCT00581074
View directory record Official record
Conditions
Obesity
Interventions
diet (grapefruit or grapefruit juice)
Behavioral
Lead sponsor
Vanderbilt University
Other
Eligibility
21 Years to 50 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2008
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jul 27, 2011 · Synced Oct 20, 2026, 5:30 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Comparison of Popular Weight Loss Diets

NCT00079573
View directory record Official record
Conditions
Obesity
Interventions
Atkins diet (extremely low carbohydrate), Zone diet (low carbohydrate, high protein), Ornish diet (very low fat)
Behavioral
Lead sponsor
National Center for Complementary and Integrative Health (NCCIH)
NIH
Eligibility
30 Years to 50 Years · Female only
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2004
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Aug 18, 2006 · Synced Oct 20, 2026, 5:30 AM EDT