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Showing 1249–1272 of 5,091 matching trials from the local directory fallback.
Recruiting No phase listed Observational Accepts healthy volunteers

Natural History Study of and Genetic Modifiers in Spinocerebellar Ataxias

NCT01060371
Conditions
Healthy Participants, RFC1 Gene Mutation, Spinocerebellar Ataxia Type 1, Spinocerebellar Ataxia Type 10, Spinocerebellar Ataxia Type 2, Spinocerebellar Ataxia Type 27b, Spinocerebellar Ataxia Type 3, Spinocerebellar Ataxia Type 6, Spinocerebellar Ataxia Type 7, Spinocerebellar Ataxia Type 8
Interventions
Assessments and Questionnaires, Blood Collection, Cerebrospinal Fluid Collection, Genetic Testing, Magnetic Resonance Imaging (MRI) Scan
Other · Genetic
Lead sponsor
Lauren Moore
Other
Eligibility
6 Years and older
Enrollment
1,400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2030
U.S. locations
16
States / cities
Los Angeles, California • San Francisco, California • Gainesville, Florida + 12 more
Recruiting Not applicable Interventional Accepts healthy volunteers

Tirzepatide Impact Assessment Study

NCT07740291
Conditions
Addiction, Cardiometabolic Health Indicators, Eating Disorders, Mental Health, Obesity & Overweight
Interventions
GLP-1 Receptor Agonist Therapy, Structured Lifestyle Intervention
Drug · Behavioral
Lead sponsor
Texas Tech University
Other
Eligibility
18 Years and older
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Lubbock, Texas
Conditions
Urea Cycle Disorder
Interventions
Not listed
Lead sponsor
St. Jude Children's Research Hospital
Other
Eligibility
16 Years to 40 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2032
U.S. locations
1
States / cities
Memphis, Tennessee
Conditions
Aging, Behavior Change, Cognitive Ability, Physical Inactivity
Interventions
Text Messaging Intervention
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
40 Years and older
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Ann Arbor, Michigan
Conditions
Cervical Carcinoma, Human Papillomavirus Infection
Interventions
Biospecimen Collection, Cervical Biopsy, Colposcopy, Electronic Health Record Review, Endocervical Curettage, Excision, HPV Self-Collection, Human Papillomavirus Test, Questionnaire Administration
Procedure · Other
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
25 Years and older · Female only
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
18
States / cities
Birmingham, Alabama • Atlanta, Georgia • Lafayette, Louisiana + 12 more
Recruiting Not applicable Interventional Accepts healthy volunteers

Enhancing Engagement of Partners in Research

NCT07166913
Conditions
Stakeholder Engagement
Interventions
Toolkit
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
480 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
New York, New York
Recruiting No phase listed Observational Accepts healthy volunteers

Platelet Volunteers, Longitudinal and Multi-omic Study

NCT07137429
Conditions
Thrombosis
Interventions
Not listed
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
18 Years to 100 Years
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2041
U.S. locations
1
States / cities
Bethesda, Maryland
Recruiting No phase listed Observational Accepts healthy volunteers

Longitudinal Validation of CIRC Technologies

NCT07081711
Conditions
Aortic Diseases, Atrial Fibrillation, Cardiovascular Diseases, Congenital Heart Disease, Heart Failure, Ischemic Heart Disease, Metabolic Cardiomyopathy, Non-ischemic Cardiomyopathy, Valvular Heart Disease, Ventricular Fibrillation
Interventions
Not listed
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
1,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2037
U.S. locations
1
States / cities
Cleveland, Ohio
Recruiting Not applicable Interventional Accepts healthy volunteers

Effect of Watermelon on Cardiometabolic Health

NCT07006636
Conditions
Cardiometabolic Health Indicators, Whole-body Antioxidant Capacity
Interventions
Sweetened placebo beverage +liquid meal test at baseline, Watermelon Juice + liquid meal test at baseline
Other
Lead sponsor
University of California, Los Angeles
Other
Eligibility
Female only
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Los Angeles, California
Recruiting Phase 2 Interventional Accepts healthy volunteers

Kick-Nic! Youth Quit Vaping App

NCT06662305
Conditions
Nicotine Vaping
Interventions
Kick-Nic! mobile phone application, NCI Quit Vaping website
Behavioral
Lead sponsor
Yale University
Other
Eligibility
12 Years to 19 Years
Enrollment
306 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
New Haven, Connecticut
Recruiting Not applicable Interventional Accepts healthy volunteers

Neural Control of Gait & Navigation in ADRD

NCT06501820
Conditions
Aging
Interventions
Transcranial direct current stimulation
Device
Lead sponsor
University of Florida
Other
Eligibility
65 Years to 89 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2030
U.S. locations
1
States / cities
Gainesville, Florida
Recruiting Not applicable Interventional Accepts healthy volunteers

Mechanistic Effect of Walnut Consumption on Sleep Quality

NCT06430086
Conditions
Poor Sleep Quality
Interventions
HCHS consumption, Walnut consumption
Other
Lead sponsor
Columbia University
Other
Eligibility
45 Years to 65 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
New York, New York
Recruiting Phase 4 Interventional Accepts healthy volunteers

Fibrosis Lessens After Metabolic Surgery

NCT06374875
Conditions
Liver Fibrosis, Metabolic Dysfunction-Associated Steatohepatitis (MASH), Metabolic Dysfunction-associated Steatotic Liver Disease (MASLD), Non-Alcoholic Fatty Liver Disease, Obesity
Interventions
Incretin-Based Therapy, Metabolic surgery
Drug · Procedure
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 75 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2029
U.S. locations
4
States / cities
Phoenix, Arizona • Indianapolis, Indiana • Rochester, Minnesota + 1 more
Conditions
Implementation Science, Informed Consent, Neonatal Screening
Interventions
Educational Website and Video
Behavioral
Lead sponsor
Erin Rothwell
Other
Eligibility
18 Years and older
Enrollment
5,980 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
2
States / cities
Salt Lake City, Utah
Conditions
Systemic Lupus Erythematosus (Sle)
Interventions
Nicotinamide Riboside
Dietary Supplement
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
18 Years to 120 Years · Female only
Enrollment
78 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Center Involved Diabetic Macular Edema, Diabetic Macular Edema
Interventions
OCU200
Drug
Lead sponsor
Ocugen
Industry
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
5
States / cities
Deerfield Beach, Florida • Erie, Pennsylvania • Bellaire, Texas + 2 more
Conditions
Breast Cancer
Interventions
Dual-Energy Contrast-Enhanced Spectral Mammography (CESM)
Diagnostic Test
Lead sponsor
American College of Radiology
Other
Eligibility
45 Years to 74 Years · Female only
Enrollment
2,032 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
12
States / cities
Birmingham, Alabama • Boca Raton, Florida • The Villages, Florida + 9 more
Conditions
Anxiety Disorders and Symptoms, Depressive Symptoms
Interventions
Space for depression, Space for resilience, The Unified Protocol for Transdiagnostic Treatment of Emotional Disorders (UP)
Behavioral
Lead sponsor
Boston University Charles River Campus
Other
Eligibility
18 Years and older
Enrollment
1,800 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Recruiting No phase listed Observational Accepts healthy volunteers

Providing Access to the Visual Environment

NCT00341744
Conditions
Vision Impairment
Interventions
Not listed
Lead sponsor
Vanderbilt University
Other
Eligibility
3 Years to 21 Years
Enrollment
795 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2001 – 2028
U.S. locations
1
States / cities
Nashville, Tennessee
Recruiting Not applicable Interventional Accepts healthy volunteers

Treating Contact Lens Discomfort With Varenicline Solution Nasal Spray 0.03mg

NCT07705893
Conditions
Dry Eye
Interventions
Tyrvaya
Drug
Lead sponsor
Ocular Aesthetics, LLC dba Ocular Clinical Trials
Other
Eligibility
18 Years to 99 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Houston, Texas
Conditions
Elbow Fractures
Interventions
Buzzy Ice pack, Flash Cards
Device · Other
Lead sponsor
University of Oklahoma
Other
Eligibility
3 Years to 10 Years
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
2
States / cities
Oklahoma City, Oklahoma
Recruiting Phase 3 Interventional Accepts healthy volunteers

Suzetrigine in Total Hip Arthroplasty

NCT07226700
Conditions
JOURNAVX, Multimodal Analgesia, Nav 1.8, Opioid Cessation, Opioid Consumption, Postoperative, Pain, Pain Management, Randomized Controlled Study, Randomized Controlled Trial, Randomized Controlled Trials, Suzetrigine, Total Hip Arthroplasty (THA), Total Hip Arthroplasty \(THA\), Total Hip Replacement, Total Hip Replacement Arthroplasty, Total Hip Replacement Surgery, Total Hip Replacements
Interventions
Placebo, Suzetrigine
Other · Drug
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
18 Years to 80 Years
Enrollment
210 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
New York, New York
Recruiting Not applicable Interventional Accepts healthy volunteers

Venous Compression in Fontan

NCT07220226
Conditions
Fontan Circulation, Single-ventricle
Interventions
Lower extremity compression garments, Without compression garments
Device · Other
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 45 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Dallas, Texas
Recruiting Phase 2 Interventional Accepts healthy volunteers

CUE-101with Pembrolizumab for Locally Advanced HPV+HNSCCs

NCT07172256
Conditions
HPV Positive Oropharyngeal Squamous Cell Carcinoma, Head and Neck Squamous Cell Carcinoma, Locally Advanced, New Diagnosis Tumor
Interventions
CUE-101, Pembrolizumab
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2031
U.S. locations
1
States / cities
New Haven, Connecticut