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ClinicalTrials.gov public records Last synced Nov 7, 2026, 9:46 AM EST

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Showing 2113–2136 of 85,906 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: 1 Clear all
Active, not recruiting Phase 2 Interventional Accepts healthy volunteers

Safety, Tolerability, and Immunogenicity of MenABCWY Administered on Different Dosing Schedules in Healthy Adolescents

NCT05087056
View directory record Official record
Conditions
Meningitis, Meningococcal
Interventions
MenABCWY vaccine, Placebo
Combination Product
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
11 Years to 14 Years
Enrollment
305 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2027
U.S. locations
24
States / cities
Birmingham, Alabama • Tucson, Arizona • Ventura, California + 19 more
Source: ClinicalTrials.gov public record
Updated Sep 28, 2026 · Synced Nov 7, 2026, 9:46 AM EST
Completed Not applicable Interventional Results available

In Vivo Assessment of the Tooth-Resin Composite Interface Using Optical Coherence Tomography

NCT05145322
View directory record Official record
Conditions
Cavity, Cavities of Teeth
Interventions
Composite with 90 degree cavosurface angle, Composite with wide bevel
Device
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 28, 2024 · Synced Nov 7, 2026, 9:46 AM EST
Completed Phase 3 Interventional Accepts healthy volunteers

Safety and Efficacy of T89 in the Prevention and Treatment of Adults With Acute Mountain Sickness (AMS)

NCT04993729
View directory record Official record
Conditions
Acute Mountain Sickness (AMS)
Interventions
T89 capsule, Placebo capsule
Drug
Lead sponsor
Tasly Pharmaceuticals, Inc.
Industry
Eligibility
18 Years to 55 Years
Enrollment
853 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Aug 13, 2024 · Synced Nov 7, 2026, 9:46 AM EST
Completed Not applicable Interventional

Effects of a Whole-food, Plant-based Nutrition Program on BP and Potassium in Subjects With CKD

NCT06343129
View directory record Official record
Conditions
Chronic Kidney Diseases
Interventions
Dietary education program
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
2
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Apr 17, 2024 · Synced Nov 7, 2026, 9:46 AM EST
Terminated Phase 3 Interventional Results available

International Study to Determine if AdreView Heart Function Scan Can be Used to Identify Patients With Mild or Moderate Heart Failure (HF) That Benefit From Implanted Medical Device

NCT02656329
View directory record Official record
Conditions
Heart Failure
Interventions
Iobenguane I -123 Injection, Implantable Cardioverter Defibrillator, Thyroid blocking
Drug · Device
Lead sponsor
GE Healthcare
Industry
Eligibility
18 Years and older
Enrollment
395 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
29
States / cities
Birmingham, Alabama • Bakersfield, California • La Mesa, California + 24 more
Source: ClinicalTrials.gov public record
Updated May 22, 2019 · Synced Nov 7, 2026, 9:46 AM EST
Terminated Phase 2 Interventional Accepts healthy volunteers Results available

IN Insulin in Type 1 Diabetes (T1D) Hypoglycemia Unawareness: Safety Only Phase

NCT04028960
View directory record Official record
Conditions
Type1diabetes
Interventions
Regular insulin (Humulin-R), intranasal route, SipNose intranasal device
Drug · Device
Lead sponsor
HealthPartners Institute
Other
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated May 18, 2021 · Synced Nov 7, 2026, 9:46 AM EST
Completed Phase 1 Interventional Accepts healthy volunteers

A Study to Investigate Efficacy and Safety of NSI-8226 in Healthy Participants

NCT06640920
View directory record Official record
Conditions
Healthy
Interventions
Cohort A, Cohort B, Cohort C, Cohort D
Biological
Lead sponsor
Uniquity One (UNI)
Industry
Eligibility
18 Years to 65 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 12, 2025 · Synced Nov 7, 2026, 9:46 AM EST
Completed Phase 1Phase 2 Interventional

IMP4297 in Combination With Temozolomide in Patients With Advanced Solid Tumors and Small Cell Lung Cancer

NCT04434482
View directory record Official record
Conditions
Advanced Solid Tumours, Small Cell Lung Cancer
Interventions
IMP4297(senaparib)
Drug
Lead sponsor
Impact Therapeutics, Inc.
Industry
Eligibility
18 Years and older
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
4
States / cities
Evergreen Park, Illinois • Canton, Ohio • Columbus, Ohio + 1 more
Source: ClinicalTrials.gov public record
Updated Sep 19, 2024 · Synced Nov 7, 2026, 9:46 AM EST
Completed Phase 2 Interventional

Transcranial Electrical Polarization to Treat Focal Hand Dystonia

NCT00106782
View directory record Official record
Conditions
Dystonia, Focal Hand Dystonia, FHD
Interventions
Transcranial Electrical Polarization (TEP)
Procedure
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2010
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 2, 2017 · Synced Nov 7, 2026, 9:46 AM EST
Completed Phase 1 Interventional Accepts healthy volunteers Results available

A Study to Evaluate the Effect of Itraconazole on the Pharmacokinetics of PF-04958242 in Healthy Subjects

NCT02341482
View directory record Official record
Conditions
Healthy
Interventions
PF-04958242, Itraconazole
Drug
Lead sponsor
Biogen
Industry
Eligibility
18 Years to 55 Years
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jan 9, 2020 · Synced Nov 7, 2026, 9:46 AM EST
Completed Phase 2 Interventional Results available

Varenicline (Chantix™) for the Treatment of Alcohol Dependence

NCT00705523
View directory record Official record
Conditions
Alcoholism
Interventions
varenicline, placebo
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 70 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 2, 2015 · Synced Nov 7, 2026, 9:46 AM EST
Terminated Not applicable Interventional Results available

Yoga to Alleviate Fatigue, Anxiety and Pain in Adolescents During Treatment for Lymphoma or Leukemia

NCT02473523
View directory record Official record
Conditions
Leukemia, Hodgkin Lymphoma, Lymphoma, Non-Hodgkin's
Interventions
PedsQL Cancer Module, PedsQL Multidimensional Fatigue Scale, Biodex System 3 Dynamometer, Jamar Hydraulic Hand Dynamometer, Sit and Reach Test, Test of Motor Proficiency, Verbal Numeric Pain Scale, :Yoga Therapy
Other · Device
Lead sponsor
St. Jude Children's Research Hospital
Other
Eligibility
13 Years to 17 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Mar 8, 2017 · Synced Nov 7, 2026, 9:46 AM EST
Completed Not applicable Interventional Accepts healthy volunteers Results available

Use of Nudges To Enhance Enrollment in Critical Care Research

NCT03284359
View directory record Official record
Conditions
Critical Illness
Interventions
Pre-Consent Nudge Bundle
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
182 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 3, 2021 · Synced Nov 7, 2026, 9:46 AM EST
Completed Not applicable Interventional Results available

Efficacy and Cost: Benefit Ratio of 0, 1, and 2 Medial Branch Blocks for Lumbar Facet Joint Radiofrequency Denervation

NCT00484159
View directory record Official record
Conditions
Low Back Pain
Interventions
Radiofrequency denervation of medial branches, 0.5% bupivacaine, 2% lidocaine, Radiofrequency denervation
Procedure · Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
151 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
2
States / cities
Washington D.C., District of Columbia • Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 26, 2011 · Synced Nov 7, 2026, 9:46 AM EST
Completed Phase 2 Interventional Results available

A Depot Formulation of Sunitinib Malate (GB-102) Compared to Aflibercept in Subjects With Wet AMD

NCT03953079
View directory record Official record
Conditions
Neovascular Age-Related Macular Degeneration
Interventions
Drug: GB-102, Aflibercept
Drug
Lead sponsor
Graybug Vision
Industry
Eligibility
50 Years and older
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
33
States / cities
Gilbert, Arizona • Phoenix, Arizona • Bakersfield, California + 28 more
Source: ClinicalTrials.gov public record
Updated Jan 19, 2022 · Synced Nov 7, 2026, 9:46 AM EST
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Ankle Splinting on Vascular Function in Aging

NCT02144896
View directory record Official record
Conditions
Aging
Interventions
Ankle splinting
Other
Lead sponsor
University of Florida
Other
Eligibility
60 Years to 79 Years
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Apr 5, 2018 · Synced Nov 7, 2026, 9:46 AM EST
Completed Phase 1 Interventional

Pharmacokinetic Study of Ceftaroline Fosamil/Avibactam in Adults With Augmented Renal Clearance

NCT01624246
View directory record Official record
Conditions
Augmented Renal Clearance (ARC), Systemic Inflammatory Response Syndrome (SIRS)
Interventions
Ceftaroline fosamil/Avibactam (CXL)
Drug
Lead sponsor
Forest Laboratories
Industry
Eligibility
18 Years to 55 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
19
States / cities
Fresno, California • Los Angeles, California • San Diego, California + 16 more
Source: ClinicalTrials.gov public record
Updated Apr 7, 2017 · Synced Nov 7, 2026, 9:46 AM EST
Completed Phase 1 Interventional Accepts healthy volunteers

Salmonella Conjugates CVD 2000: Study of Responses to Vaccination With Trivalent Salmonella Conjugate Vaccine to Prevent Invasive Salmonella Disease

NCT05525546
View directory record Official record
Conditions
Risk Reduction
Interventions
Trivalent Salmonella Conjugate Vaccine (TSCV) Full-Strength Formulation, Trivalent Salmonella Conjugate Vaccine (TSCV) Half-Strength Formulation, Trivalent Salmonella Conjugate Vaccine (TSCV) Dilutional Half-Strength Formulation, Placebo
Biological · Other
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years to 49 Years
Enrollment
82 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 21, 2023 · Synced Nov 7, 2026, 9:46 AM EST
Completed Early Phase 1 Interventional Results available

Extending taVNS Paired With Infant CIMT Into a Home-Based Setting

NCT05857527
View directory record Official record
Conditions
Cerebral Palsy
Interventions
Custom EMG triggered Soterix taVNS stimulation with CIMT therapy in lab, Custom EMG triggered Soterix taVNS stimulation with CIMT therapy in home
Combination Product
Lead sponsor
Medical University of South Carolina
Other
Eligibility
6 Months to 18 Months
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jul 4, 2025 · Synced Nov 7, 2026, 9:46 AM EST
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Study of the Safety and Contraceptive Efficacy of C31G Compared to Conceptrol®

NCT00274261
View directory record Official record
Conditions
Pregnancy
Interventions
C31G, nonoxynol-9 (N-9)
Drug
Lead sponsor
Premier Research
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
1,565 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2008
U.S. locations
15
States / cities
Berkeley, California • Los Angeles, California • Aurora, Colorado + 11 more
Source: ClinicalTrials.gov public record
Updated May 1, 2018 · Synced Nov 7, 2026, 9:46 AM EST
Completed Phase 4 Interventional

Diuretics and Volume Overload in Early CKD

NCT05171686
View directory record Official record
Conditions
Chronic Kidney Disease, Hypertension
Interventions
Diuretic augmentation (hydrochlorothiazide, chlorthalidone, furosemide, torsemide, or bumetanide)
Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 21, 2026 · Synced Nov 7, 2026, 9:46 AM EST
Completed Phase 2 Interventional Results available

Encorafenib, Binimetinib and Cetuximab in Subjects With Previously Untreated BRAF-mutant ColoRectal Cancer

NCT03693170
View directory record Official record
Conditions
BRAF V600E-mutant Metastatic Colorectal Cancer
Interventions
encorafenib, Binimetinib, Cetuximab
Drug
Lead sponsor
Pierre Fabre Medicament
Industry
Eligibility
18 Years and older
Enrollment
95 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
2
States / cities
New York, New York • Germantown, Tennessee
Source: ClinicalTrials.gov public record
Updated Jul 16, 2026 · Synced Nov 7, 2026, 9:46 AM EST
Recruiting Not applicable Interventional

Occupational Therapy and Registered Dietitian Services to Reduce Fall Risk Among Home Delivered Meal Clients

NCT06586970
View directory record Official record
Conditions
Diet, Food and Nutrition, Accidental Falls, Cardiovascular Diseases, Diabetes, Debility, Frailty, Functional Disability
Interventions
Meals + RD services, Meals + OT services, Meals + RD + OT services
Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
60 Years and older
Enrollment
750 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 13, 2026 · Synced Nov 7, 2026, 9:46 AM EST
Completed Phase 2 Interventional

Efficacy of SBR759 in Lowering Serum Phosphate Levels in Chronic Kidney Disease Patients on Hemodialysis

NCT00704483
View directory record Official record
Conditions
Hyperphosphatemia Patients With Chronic Kidney Disease on 3x/Week Replacement Therapy
Interventions
SBR759, Sevelamer HCl
Drug
Lead sponsor
Novartis Pharmaceuticals
Industry
Eligibility
18 Years and older
Enrollment
321 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2008
U.S. locations
19
States / cities
Chula Vista, California • La Mesa, California • Whittier, California + 16 more
Source: ClinicalTrials.gov public record
Updated Dec 19, 2020 · Synced Nov 7, 2026, 9:46 AM EST