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ClinicalTrials.gov public records Last synced Nov 15, 2026, 4:20 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 25–48 of 272 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: 12-weeks of Weight Loss Clear all

Conditions: Insulin Resistance and Type 2 Diabetes
Interventions: Weight loss - diet only, Weight loss plus exercise; Behavioral
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years to 45 Years · Female only
Enrollment: 36 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2003 – 2007
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Overweight, Obesity
Interventions: Disseminating Effective Habits for Long-term Weight Loss, Achieve Together website; Behavioral
Lead sponsor: Penn State University; Other
Eligibility: 21 Years to 65 Years
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2010
U.S. locations: 1
States / cities: Hershey, Pennsylvania

Conditions: Diabetes
Interventions: DPP-GLB Standard, DPP-GLB Enhanced; Behavioral
Lead sponsor: Lovoria Williams; Other
Eligibility: 18 Years and older
Enrollment: 403 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2026
U.S. locations: 21
States / cities: Frankfort, Kentucky • Lexington, Kentucky • Louisville, Kentucky + 2 more

Conditions: Obesity
Interventions: THIAA, Placebo; Dietary Supplement
Lead sponsor: MetaProteomics LLC; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 130 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2012
U.S. locations: 1
States / cities: Gig Harbor, Washington

Conditions: Post-COVID Conditions, Obesity
Interventions: 12-weeks of Weight Loss, 12-weeks of Weight Stability; Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: Up to 80 Years
Enrollment: 150 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2029
U.S. locations: 2
States / cities: Baltimore, Maryland • San Antonio, Texas

Conditions: Weight Loss, Diet, Healthy, Cardiovascular Risk Factor
Interventions: Med-South Weight Loss Intervention, WW; Behavioral
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 18 Years to 75 Years
Enrollment: 360 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2024
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: Malnutrition
Interventions: Immediate Intervention Group, Delayed Intervention Group; Behavioral
Lead sponsor: US Department of Veterans Affairs; Federal
Eligibility: 65 Years and older
Enrollment: 222 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2013
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Overweight and Obesity
Interventions: high dairy diet, Low Dairy; Other
Lead sponsor: USDA, Western Human Nutrition Research Center; Federal
Eligibility: 20 Years to 50 Years
Enrollment: 78 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2006 – 2009
U.S. locations: 1
States / cities: Davis, California

Conditions: Obesity
Interventions: Behavioral weight loss intervention (Online; Rx Weight Loss), Minority stress intervention, Social support intervention, Negative body image intervention; Behavioral
Lead sponsor: The Miriam Hospital; Other
Eligibility: 18 Years to 70 Years · Female only
Enrollment: 88 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Obesity
Interventions: Continuous Caloric Restriction versus Intermittent Caloric Restriction on Fat Loss; Behavioral
Lead sponsor: Coastal Carolina University; Other
Eligibility: 18 Years to 65 Years · Female only
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Conway, South Carolina

Conditions: Liver Cirrhoses, Portal Hypertension Related to Cirrhosis, Severe Obesity, TIPS
Interventions: Transjugular Intrahepatic Portosystemic Shunt (TIPS), Sleeve Gastrectomy, Anti-Obesity Pharmacotherapy (Class Effect), Lifestyle Counseling - Diet & Physical-Activity Program; Procedure · Drug · Behavioral
Lead sponsor: The Cleveland Clinic; Other
Eligibility: 18 Years to 70 Years
Enrollment: 70 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2034
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Obesity
Interventions: lorcaserin hydrochloride XR, Placebo; Drug
Lead sponsor: Eisai Inc.; Industry
Eligibility: 12 Years to 17 Years
Enrollment: 278 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2020
U.S. locations: 16
States / cities: Phoenix, Arizona • Bell Gardens, California • Long Beach, California + 13 more

Conditions: Obesity
Interventions: group sessions, sibutramine, orlistat, diethylpropion, Low Calorie Diet, Health One, Intensive Medical Combination Therapy for Obesity, Control Condition; Behavioral · Drug · Other
Lead sponsor: Pennington Biomedical Research Center; Other
Eligibility: 20 Years to 60 Years
Enrollment: 390 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2008
U.S. locations: 1
States / cities: Baton Rouge, Louisiana

Conditions: Obesity and Overweight
Interventions: Standard Medical Care (SMC), Monitoring Contacts, Aerobic Training, Resistance Training, Nutrition Education; Other · Behavioral
Lead sponsor: University of Kansas Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Kansas City, Kansas

Conditions: Cardiovascular Diseases, Obesity
Interventions: Online Behavioral Weight Loss Program, Physical Activity Intervention, Bite Counter, Virtual Reality, Virtual Meetings; Behavioral
Lead sponsor: The Miriam Hospital; Other
Eligibility: 21 Years to 75 Years
Enrollment: 198 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2024
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Cancer Survivorship, Obesity, Overweight
Interventions: Group-based education and discussion, Individual 1:1 counseling, Group based behavioral skills development and cooking demonstrations, BfitBwell; Behavioral
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 18 Years to 75 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Sleep, Body Composition
Interventions: Normal protein, High protien; Other
Lead sponsor: Purdue University; Other
Eligibility: 35 Years to 69 Years
Enrollment: 71 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: West Lafayette, Indiana

Conditions: Overweight and Obesity, Weight Loss Maintenance, Dietary Habits
Interventions: Weight Loss Maintenance (Control vs. Reverse Diet); Behavioral
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 21 Years to 70 Years
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2022
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Overweight, Obesity
Interventions: Phone-based sessions (28 total) on a structured schedule, Phone-based sessions upon request, Weight self-monitoring, Dietary and physical activity self-monitoring, Scheduled tailored interventionist feedback, Dietary goals, Meal replacements, Physical activity goals, Toolbox, Challenges, Tailored interventionist feedback upon request; Behavioral
Lead sponsor: University of Tennessee; Other
Eligibility: 18 Years and older
Enrollment: 248 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2018
U.S. locations: 1
States / cities: San Antonio, Texas

Conditions: Health Behavior
Interventions: health coaching; Behavioral
Lead sponsor: University of Michigan; Other
Eligibility: 21 Years to 100 Years
Enrollment: 82 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Pediatric Obesity
Interventions: NOURISH, Wellness Group; Behavioral · Other
Lead sponsor: Virginia Commonwealth University; Other
Eligibility: 18 Years and older
Enrollment: 184 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2010
U.S. locations: 1
States / cities: Richmond, Virginia

Conditions: Crohn Disease
Interventions: Tirzepatide, Mediterranean diet; Drug · Behavioral
Lead sponsor: University of Miami; Other
Eligibility: 18 Years and older
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Miami, Florida

Conditions: Overweight, Obesity, Blood Sugar Regulation, Appetite Suppression, Weight Management
Interventions: Evolv GLP-1 Group, Control Group; Dietary Supplement · Other
Lead sponsor: Evolv; Industry
Eligibility: 18 Years and older
Enrollment: 98 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026
U.S. locations: 1
States / cities: Las Vegas, Nevada

Conditions: Diabetes Mellitus, Type 2, Diabetes Mellitus, Type II, Diabetes Mellitus, Adult-Onset, Inflammation
Interventions: Victoza (liraglutide) with dietician monitoring, Placebo with dietician monitoring; Drug · Other
Lead sponsor: Stanford University; Other
Eligibility: 40 Years to 69 Years
Enrollment: 56 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2019
U.S. locations: 1
States / cities: Stanford, California

Search by objective public record fields.

Fatty Acid Metabolism and Insulin Sensitivity: the Role of Endurance Exercise

Disseminating Effective Habits for Long-Term Weight Loss

Enhanced DPP-GLB to Promote Weight Loss Among Nonresponders in a Community-Based Lifestyle Intervention.

Effect of a Novel Nutraceutical on Weight Loss and Weight Maintenance in Obese Subjects

Modifying Adiposity Through Behavioral Strategies to Improve COVID-19 Rehabilitation

Delicious Eating for Life in Southern Homes

Prevention of Weight Loss in Long Term Care Veterans

Dairy Foods and Weight Loss

Optimizing an Online Behavioral Weight Loss Intervention and Novel Culturally Tailored Components for Sexual Minority Women

The Effects of Continuous vs. Intermittent Caloric Restriction on Fat Los

Optimizing Portal Hypertension With TIPS and Interval Metabolic Surgery for Advanced Liver Disease

Study to Evaluate the Efficacy and Safety of Belviq XR® in Conjunction With Lifestyle Modification for Weight Loss in Obese Adolescents, Age 12 to 17 Years

LOSS- Louisiana Obese Subjects Study

Muscle and Movement With Anti-Obesity Medications

Creating an Optimized Technology-Based Weight Loss Program for Cardiac Rehabilitation Patients

BfedBwell Proof-of-Concept Pilot

Impact of Protein Quantity Within the USDA Healthy Style Eating Pattern on Sleep

Feasibility and Preliminary Efficacy of a Reverse Diet as a Novel Weight Loss Maintenance Strategy for Weight-Reduced Adults With Overweight/Obesity

Dissemination of the Look Ahead Weight Management Treatment in the Military

My Health Coach Study

NOURISH: Nourishing Our Understanding of Role Modeling to Improve Support and Health

Glucagon-like Peptide-1 Receptor Agonist (GLP-1 RA) and Diet in Inflammatory Bowel Disease (IBD) Patients

A Controlled Study to Evaluate the Effects of a Supplement on Weight Loss, Blood Sugar, and Appetite Suppression

Effect of Liraglutide (Victoza) on Inflammation in Human Adipose Tissue and Blood