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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: 12-weeks of Weight Loss Clear all
Completed Not applicable Interventional

Refining Novel Culturally Tailored Behavioral Weight Loss Treatment Components for Sexual Minority Women With Obesity

NCT05036187
View directory record Official record
Conditions
Obesity
Interventions
Behavioral Weight Loss Intervention, Minority Stress Intervention, Negative Body Image Intervention, Social Support Intervention
Behavioral
Lead sponsor
The Miriam Hospital
Other
Eligibility
18 Years to 70 Years · Female only
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Mar 1, 2023 · Synced Sep 29, 2026, 12:34 AM EDT
Completed Phase 2Phase 3 Interventional Results available

LapBand Adjustment to Improve Early Weight Loss

NCT01060592
View directory record Official record
Conditions
Obesity
Interventions
EndoFLIP device (FDA Device Listing Number : D091203)
Device
Lead sponsor
Crospon
Industry
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Hurst, Texas
Source: ClinicalTrials.gov public record
Updated Apr 7, 2013 · Synced Sep 29, 2026, 12:34 AM EDT
Completed Not applicable Interventional

Engaging Patients in Weight Loss Tools

NCT04121312
View directory record Official record
Conditions
Obesity
Interventions
Facilitation Intervention
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 75 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
2
States / cities
Gainesville, Florida • Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Jan 15, 2024 · Synced Sep 29, 2026, 12:34 AM EDT
Completed Not applicable Interventional Results available

OA Clinic-Community CARE Model

NCT05349500
View directory record Official record
Conditions
Osteoarthritis, Knee, Osteoarthritis, Hip, Overweight, Obesity, Physical Inactivity, Weight Loss
Interventions
OA CARE Intervention, Usual Care control group
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 99 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 13, 2025 · Synced Sep 29, 2026, 12:34 AM EDT
Terminated Not applicable Interventional

How Gas-Filled Intragastric Balloons or Endoscopic Sleeve Gastroplasty Affect Hunger, Hunger Hormones, and Gastric Emptying Compared to Meal Replacements

NCT04306445
View directory record Official record
Conditions
Obesity
Interventions
GF-IGB: Obalon Balloon, Medically Supervised Meal Replacement Program: My New Weigh, Endoscopic sleeve gastroplasty: (ESG)
Device · Dietary Supplement · Procedure
Lead sponsor
University of Colorado, Denver
Other
Eligibility
22 Years to 65 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Jun 1, 2026 · Synced Sep 29, 2026, 12:34 AM EDT
Completed Phase 2Phase 3 Interventional

Effects of Intentional Weight Loss Interventions in Chronic Kidney Disease

NCT01180101
View directory record Official record
Conditions
Chronic Kidney Disease, Obesity
Interventions
Diet and exercise, Bariatric Surgery
Behavioral · Procedure
Lead sponsor
The Cleveland Clinic
Other
Eligibility
19 Years to 99 Years
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 26, 2016 · Synced Sep 29, 2026, 12:34 AM EDT
Terminated Phase 4 Interventional Accepts healthy volunteers Results available

Study to Evaluate the Efficacy and Safety of Belviq XR® in Conjunction With Lifestyle Modification for Weight Loss in Obese Adolescents, Age 12 to 17 Years

NCT03338296
View directory record Official record
Conditions
Obesity
Interventions
lorcaserin hydrochloride XR, Placebo
Drug
Lead sponsor
Eisai Inc.
Industry
Eligibility
12 Years to 17 Years
Enrollment
278 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
16
States / cities
Phoenix, Arizona • Bell Gardens, California • Long Beach, California + 13 more
Source: ClinicalTrials.gov public record
Updated Jul 18, 2021 · Synced Sep 29, 2026, 12:34 AM EDT
Completed Phase 4 Interventional Results available

A Phase IV Safety and Efficacy Study of VI-0521 in Adolescents With Obesity

NCT03922945
View directory record Official record
Conditions
Adolescent Obesity, Obesity in Adolescence, Adolescent Overweight
Interventions
VI-0521 oral capsule, Placebo oral capsule, Lifestyle Modification
Drug · Behavioral
Lead sponsor
VIVUS LLC
Industry
Eligibility
12 Years to 16 Years
Enrollment
223 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Norman, Oklahoma
Source: ClinicalTrials.gov public record
Updated Sep 9, 2022 · Synced Sep 29, 2026, 12:34 AM EDT
Completed Phase 1Phase 2 Interventional

Patient-Centered Weight Loss Program for Knee Replacement Patients

NCT02728661
View directory record Official record
Conditions
ARTHROPLASTY, REPLACEMENT
Interventions
PACE, Delayed PACE
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
40 Years to 79 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 25, 2023 · Synced Sep 29, 2026, 12:34 AM EDT
Active, not recruiting Phase 2 Interventional

An Open-Label Pilot Intervention Trial to Prevent Diabetes in Prediabetic Adult Survivors of Childhood Cancer

NCT04742751
View directory record Official record
Conditions
PreDiabetes, Adult Children
Interventions
Metformin, Digital Intervention
Drug · Behavioral
Lead sponsor
St. Jude Children's Research Hospital
Other
Eligibility
18 Years to 44 Years
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Apr 29, 2026 · Synced Sep 29, 2026, 12:34 AM EDT
Not listed Phase 4 Interventional Accepts healthy volunteers

Effect of Daily Glucomannan in Overweight Patients

NCT01485718
View directory record Official record
Conditions
Overweight, Obesity
Interventions
Glucomannan, Placebo
Dietary Supplement
Lead sponsor
ProMedica Health System
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Toledo, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 12, 2011 · Synced Sep 29, 2026, 12:34 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Get Active and Eat Right: Moms at Work

NCT01668316
View directory record Official record
Conditions
Overweight, Obesity
Interventions
Weight loss
Behavioral
Lead sponsor
University of North Carolina, Greensboro
Other
Eligibility
18 Years and older · Female only
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
Greensboro, North Carolina
Source: ClinicalTrials.gov public record
Updated May 2, 2019 · Synced Sep 29, 2026, 12:34 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Weight Loss and Maintenance for Rural, African American Communities of Faith (The WORD)

NCT02169947
View directory record Official record
Conditions
Obesity
Interventions
Weight loss core, Weight loss core plus maintenance
Behavioral
Lead sponsor
University of Arkansas
Other
Eligibility
18 Years and older
Enrollment
425 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2018
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Mar 28, 2018 · Synced Sep 29, 2026, 12:34 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Weight Loss Before Total Joint Arthroplasty Using A Remote Dietitian and Mobile App

NCT04330391
View directory record Official record
Conditions
Arthroplasties, Replacement, Weight Loss, Nutrition
Interventions
Remote dietitian supervised weight loss intervention and mobile app
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
3
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 8, 2024 · Synced Sep 29, 2026, 12:34 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Optimizing Weight Loss Outcomes Through Body Image Enhancement

NCT05090293
View directory record Official record
Conditions
Overweight and Obesity
Interventions
Experimental: Lifestyle Intervention with Body Image Treatment (LIBI), Lifestyle Intervention (LI)
Behavioral
Lead sponsor
Texas Tech University
Other
Eligibility
18 Years and older · Female only
Enrollment
58 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
2
States / cities
Lubbock, Texas
Source: ClinicalTrials.gov public record
Updated Nov 2, 2022 · Synced Sep 29, 2026, 12:34 AM EDT
Terminated Phase 4 Interventional Results available

LOSS- Louisiana Obese Subjects Study

NCT00115063
View directory record Official record
Conditions
Obesity
Interventions
group sessions, sibutramine, orlistat, diethylpropion, Low Calorie Diet, Health One, Intensive Medical Combination Therapy for Obesity, Control Condition
Behavioral · Drug · Other
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
20 Years to 60 Years
Enrollment
390 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2008
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Feb 21, 2016 · Synced Sep 29, 2026, 12:34 AM EDT
Completed Phase 2 Interventional Results available

A Study of the Safety and Effectiveness of Canagliflozin (JNJ-28431754) in Promoting Weight Loss in Overweight and Obese Patients Who do Not Have Diabetes

NCT00650806
View directory record Official record
Conditions
Obesity
Interventions
Canagliflozin (JNJ-28431754), Placebo
Drug
Lead sponsor
Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Industry
Eligibility
18 Years to 65 Years
Enrollment
376 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008
U.S. locations
35
States / cities
Hot Springs, Arkansas • Walnut Creek, California • Westlake Village, California + 32 more
Source: ClinicalTrials.gov public record
Updated May 23, 2013 · Synced Sep 29, 2026, 12:34 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Exercise and Weight Control

NCT03413826
View directory record Official record
Conditions
Obesity, Exercise Reinforcement
Interventions
Exercise
Behavioral
Lead sponsor
University of Kentucky
Other
Eligibility
18 Years to 40 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Dec 12, 2019 · Synced Sep 29, 2026, 12:34 AM EDT
Completed Not applicable Interventional

Vertical Sleeve Gastrectomy and Lifestyle Modification for the Treatment of Non-Alcoholic Steatohepatitis

NCT03587831
View directory record Official record
Conditions
NASH - Nonalcoholic Steatohepatitis
Interventions
Vertical Sleeve Gastrectomy, Lifestyle Modification Counseling
Procedure · Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
30 Years to 70 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
4
States / cities
San Francisco, California • Baton Rouge, Louisiana • Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 27, 2026 · Synced Sep 29, 2026, 12:34 AM EDT
Recruiting Not applicable Interventional

EMPOWER: Effects of Weight Loss and Exercise Post-stroke

NCT05901675
View directory record Official record
Conditions
Obesity, Stroke
Interventions
Lifestyle Management Program, Post-stroke Optimization of Walking using Explosive Resistance
Other
Lead sponsor
Medical University of South Carolina
Other
Eligibility
35 Years to 85 Years
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 14, 2026 · Synced Sep 29, 2026, 12:34 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Pilot Study of Time Restricted Feeding as a Weight Loss Intervention

NCT03571048
View directory record Official record
Conditions
Obesity
Interventions
Reduced Calorie Diet (RCD), Time Restricted Feeding (TRF)
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 50 Years
Enrollment
95 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Oct 24, 2022 · Synced Sep 29, 2026, 12:34 AM EDT
Completed Phase 3 Interventional

Surgery Or Lifestyle Intervention for Type 2 Diabetes (SOLID)

NCT01040468
View directory record Official record
Conditions
Type 2 Diabetes
Interventions
Roux-en-Y Gastric Bypass surgery, Laparoscopic Adjustable Gastric Banding surgery, Intensive Lifestyle Modification
Procedure · Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 65 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2015
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 18, 2016 · Synced Sep 29, 2026, 12:34 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Approaches for Improving Long-term Weight Loss

NCT03799289
View directory record Official record
Conditions
Obesity
Interventions
Behavioral weight loss followed by yoga instruction, Behavioral weight loss followed by cooking/dietary education instruction
Behavioral
Lead sponsor
The Miriam Hospital
Other
Eligibility
18 Years to 60 Years · Female only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Oct 27, 2021 · Synced Sep 29, 2026, 12:34 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Cerebrospinal Fluid Biomarkers in Bariatric Surgery

NCT04350892
View directory record Official record
Conditions
Obesity
Interventions
Roux-en-Y Gastric Bypass (RYGB), Sleeve Gastrectomy (SG), Very Low Calorie Diet (VLCD)
Procedure · Behavioral
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 65 Years
Enrollment
51 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2025
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 27, 2026 · Synced Sep 29, 2026, 12:34 AM EDT