Search | Clinical Trials Finder

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Nov 15, 2026, 1:18 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–16 of 16 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: 24 hours hypothermia Clear all

Conditions: Hypoxic-Ischemic Encephalopathy
Interventions: Holding during cooling; Other
Lead sponsor: Alexa Craig; Other
Eligibility: 24 Hours to 3 Days
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017
U.S. locations: 1
States / cities: Portland, Maine

Conditions: Ischemic Stroke, Hypothermia
Interventions: Mild Hypothermia; Other
Lead sponsor: WellStar Health System; Other
Eligibility: 18 Years to 85 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2015
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Acute Ischemic Stroke
Interventions: Caffeinol, hypothermia; Drug · Procedure
Lead sponsor: The University of Texas Health Science Center, Houston; Other
Eligibility: 18 Years to 80 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2009
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Heart Arrest, Intracranial Pressure Increase
Interventions: Ocular ultrasound; Other
Lead sponsor: TriHealth Inc.; Other
Eligibility: 18 Years and older
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Cincinnati, Ohio

Conditions: Hypoxic-Ischemic Encephalopathy, Brain Injury, Neonatal Seizure
Interventions: Neurologic examination; Other
Lead sponsor: McGill University Health Centre/Research Institute of the McGill University Health Centre; Other
Eligibility: Up to 6 Hours
Enrollment: 63 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2017
U.S. locations: 4
States / cities: Detroit, Michigan • Columbus, Ohio • Providence, Rhode Island + 1 more

Conditions: Cardiac Arrest, Out-Of-Hospital, Hypothermia, Induced, Hypoxia-Ischemia, Brain
Interventions: Therapeutic Hypothermia; Device
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years and older
Enrollment: 1,158 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2026
U.S. locations: 76
States / cities: Birmingham, Alabama • Tucson, Arizona • Los Angeles, California + 57 more

Conditions: Cardiac Arrest, Out-Of-Hospital, Hypothermia, Induced, Hypoxia-Ischemia, Brain
Interventions: Therapeutic Hypothermia; Device
Lead sponsor: University of Michigan; Other
Eligibility: 2 Days to 17 Years
Enrollment: 900 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2028
U.S. locations: 53
States / cities: Birmingham, Alabama • Phoenix, Arizona • Tucson, Arizona + 44 more

Conditions: Acute Kidney Injury, HIE
Interventions: Single Dose Theophylline, Repeat Dose Theophylline; Drug
Lead sponsor: Medical College of Wisconsin; Other
Eligibility: 1 Hour to 18 Hours
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: Oklahoma City, Oklahoma

Conditions: Post-Cardiac Arrest Syndrome
Interventions: Xenon; Combination Product
Lead sponsor: Invero Pharma, Inc.; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 1,436 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2030
U.S. locations: 8
States / cities: Hartford, Connecticut • Gainesville, Florida • Gulfport, Mississippi + 5 more

Conditions: Preterm Birth, Blood Transfusion Complication, Hypothermia
Interventions: Ranger blood warmer (3M Healthcare, Oakdale, Minnesota); Device
Lead sponsor: University of South Carolina; Other
Eligibility: 24 Weeks to 32 Weeks
Enrollment: 140 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2026
U.S. locations: 1
States / cities: Columbia, South Carolina

Conditions: Encephalopathy, Hypoxic-Ischemic
Interventions: Clonidine (Duraclon®); Drug
Lead sponsor: Johns Hopkins University; Other
Eligibility: 35 Weeks to 42 Weeks
Enrollment: 13 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2015
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Cardiac Arrest, Brain Injury
Interventions: 72 hours hypothermia, 24 hours hypothermia; Other
Lead sponsor: University of Pittsburgh; Other
Eligibility: 1 Week to 17 Years
Enrollment: 34 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2015
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Spinal Cord Injury, Acute
Interventions: Alsius Icy CoolGuard® Catheter; Device
Lead sponsor: University of Miami; Other
Eligibility: 18 Years to 70 Years
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2027
U.S. locations: 7
States / cities: Phoenix, Arizona • Miami, Florida • Atlanta, Georgia + 4 more

Conditions: Cardiogenic Shock
Interventions: IVTM™ System, Quattro® Catheter; Device
Lead sponsor: University of Chicago; Other
Eligibility: 18 Years to 89 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2021
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Ischemic Brain Injury
Interventions: xenon, Hypothermia; Drug · Other
Lead sponsor: Turku University Hospital; Government
Eligibility: 18 Years to 80 Years
Enrollment: 110 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2014
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Acute Kidney Injury, Hypoxic-Ischemic Encephalopathy, Caffeine
Interventions: Caffeine citrate; Drug
Lead sponsor: University of Arkansas; Other
Eligibility: 0 Hours to 24 Hours
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024
U.S. locations: 2
States / cities: Little Rock, Arkansas

Search by objective public record fields.

Holding, Stress, and Bonding During Therapeutic Hypothermia

Reperfusion With Cooling in Cerebral Acute Ischemia II

Caffeinol Hypothermia Protocol

Neuroprognostication Using Optic Nerve Sheath Diameter

Prospective Research in Infants With Mild Encephalopathy

Influence of Cooling Duration on Efficacy in Cardiac Arrest Patients

Pediatric Influence of Cooling Duration on Efficacy in Cardiac Arrest Patients (P-ICECAP)

Theophylline Prophylaxis During Hypothermia to Limit Neonatal Nephron Damage

Xenon for Neuroprotection During Post-Cardiac Arrest Syndrome in Comatose Survivors of an Out of Hospital Cardiac Arrest

Blood Warming in Preterm Infants to Decrease Hypothermia

Safety of Clonidine in Infants With Hypoxic Ischemic Encephalopathy During Therapeutic Hypothermia

Duration of Hypothermia for Neuroprotection After Pediatric Cardiac Arrest

Systemic Hypothermia in Acute Cervical Spinal Cord Injury

Cardiogenic Shock Intravascular Cooling Trial

Effect of Xenon and Therapeutic Hypothermia, on the Brain and on Neurological Outcome Following Brain Ischemia in Cardiac Arrest Patients

PK and Safety of Caffeine in Neonates With Hypoxic Ischemic Encephalopathy Receiving Therapeutic Hypothermia