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Filters: Intervention: 40% N2O Clear all

Conditions: Opioid-Related Disorders, Substance-Related Disorders
Interventions: 20% N2O, 40% N2O, 60% N2O, 80% N2O; Drug
Lead sponsor: University of Chicago; Other
Eligibility: 22 Years to 34 Years
Enrollment: 11 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 1995 – 1996
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Opioid-Related Disorders, Substance-Related Disorders
Interventions: Nitrous oxide; Drug
Lead sponsor: University of Chicago; Other
Eligibility: 21 Years to 37 Years
Enrollment: 10 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 1995 – 1996
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Emergence Agitation
Interventions: Depth of anesthesia; Other
Lead sponsor: Duke University; Other
Eligibility: 2 Years to 8 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2010
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Opioid-Related Disorders, Substance-Related Disorders
Interventions: 0% N2O, 10% N2O, 20% N2O, 30% N2O, 40% N2O; Drug
Lead sponsor: University of Chicago; Other
Eligibility: 21 Years to 29 Years
Enrollment: 11 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 1994 – 1996
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Opioid-Related Disorders, Substance-Related Disorders
Interventions: 20% N2O, 30% N2O, 40% N2O; Drug
Lead sponsor: University of Chicago; Other
Eligibility: 21 Years to 37 Years
Enrollment: 10 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 1993 – 1995
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Opioid-Related Disorders, Substance-Related Disorders
Interventions: 0% N2O, 40% N2O; Drug
Lead sponsor: University of Chicago; Other
Eligibility: 21 Years to 32 Years
Enrollment: 12 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 1993 – 1995
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Opioid-Related Disorders, Substance-Related Disorders
Interventions: 40% Nitrous oxide, Sham comparator, 0.2% isoflurane, 0.4% isoflurane, 0.6% isoflurane; Drug · Other
Lead sponsor: University of Chicago; Other
Eligibility: 21 Years to 34 Years · Male only
Enrollment: 10 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 1995
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Opioid-Related Disorders, Substance-Related Disorders
Interventions: Nitrous oxide 10% & placebo, Nitrous oxide 20% & placebo, Nitrous oxide 30% & placebo, Nitrous oxide 40% and placebo; Drug
Lead sponsor: University of Chicago; Other
Eligibility: 21 Years to 32 Years
Enrollment: 22 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 1996 – 1997
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Healthy
Interventions: Nitrous Oxide Gas for Inhalation; Drug
Lead sponsor: University of Michigan; Other
Eligibility: 21 Years to 40 Years
Enrollment: 21 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Abortion in First Trimester
Interventions: Nitrous oxide administration; Other
Lead sponsor: University of New Mexico; Other
Eligibility: 18 Years and older · Female only
Enrollment: 140 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2015
U.S. locations: 1
States / cities: Albuquerque, New Mexico

Conditions: Tinnitus
Interventions: Nitrous oxide gas for inhalation, Placebo gas for inhalation; Drug
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 18 Years to 65 Years
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Obstructive Sleep Apnea
Interventions: One handed mask airway, switch to two hands, Two handed mask airway + jaw thrust, Two handed mask airway, switch to one hand; Procedure
Lead sponsor: Nemours Children's Clinic; Other
Eligibility: 1 Year to 8 Years
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Wilmington, Delaware

Conditions: Opioid-Related Disorders, Substance-Related Disorders
Interventions: 10% N2O, 20% N2O, 30% N2O, 40% N2O; Drug
Lead sponsor: University of Chicago; Other
Eligibility: 21 Years to 37 Years
Enrollment: 16 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 1994 – 1996
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Alcohol-Related Disorders, Opioid-Related Disorders, Substance-Related Disorders
Interventions: 0% N2O and 10% N2O, 0% N2O and 20% N2O, 0% N2O and 30% N2O, 0% N2O and 40% N2O; Drug
Lead sponsor: University of Chicago; Other
Eligibility: 21 Years to 37 Years
Enrollment: 19 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 1995 – 1997
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Anesthesia, Tooth Extraction
Interventions: Midazolam Hydrochloride, Fentanyl, Ketamine, Propofol injection, Nitrous oxide; Drug
Lead sponsor: Albert Einstein College of Medicine; Other
Eligibility: 16 Years and older
Enrollment: 73 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2024
U.S. locations: 1
States / cities: The Bronx, New York