- Conditions
- Parkinson's Disease
- Interventions
- AAV2-GDNF
- Biological
- Lead sponsor
- Brain Neurotherapy Bio, Inc.
- Industry
- Eligibility
- 35 Years to 75 Years
- Enrollment
- 11 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2027
- U.S. locations
- 3
- States / cities
- Irvine, California • San Francisco, California • Columbus, Ohio
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- Conditions
- Multiple System Atrophy
- Interventions
- AAV2-GDNF gene therapy, Sham (Placebo) Surgery
- Biological · Procedure
- Lead sponsor
- Brain Neurotherapy Bio, Inc.
- Industry
- Eligibility
- 35 Years to 75 Years
- Enrollment
- 9 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2028
- U.S. locations
- 7
- States / cities
- Irvine, California • Boca Raton, Florida • Boston, Massachusetts + 4 more
- Conditions
- Parkinson Disease
- Interventions
- AAV2-GDNF gene therapy, control surgery
- Drug · Procedure
- Lead sponsor
- AskBio Inc
- Industry
- Eligibility
- 45 Years to 75 Years
- Enrollment
- 127 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2028
- U.S. locations
- 34
- States / cities
- Phoenix, Arizona • Irvine, California • Loma Linda, California + 26 more
- Conditions
- Parkinson's Disease
- Interventions
- Convection enhanced delivery/AAV2-GDNF
- Genetic
- Lead sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
- NIH
- Eligibility
- 18 Years and older
- Enrollment
- 25 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2022
- U.S. locations
- 1
- States / cities
- Bethesda, Maryland
- Conditions
- Idiopathic Parkinson's Disease
- Interventions
- CERE-120: Adeno-Associated Virus Delivery of Neurturin, Sham Surgery
- Biological · Procedure
- Lead sponsor
- Sangamo Therapeutics
- Industry
- Eligibility
- 35 Years to 70 Years
- Enrollment
- 57 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2017
- U.S. locations
- 11
- States / cities
- Birmingham, Alabama • Palo Alto, California • San Francisco, California + 6 more