- Conditions
- Variola Major (Smallpox)
- Interventions
- Placebo, MVA-BN
- Drug · Biological
- Lead sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
- NIH
- Eligibility
- 18 Years to 60 Years
- Enrollment
- 24 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2008 – 2012
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
Search Results
Search by objective public record fields.
Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results are retrieved from ClinicalTrials.gov and synchronized into the directory. Search pages remain noindex by default.
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Showing 1–24
of 24
matching trials from the live ClinicalTrials.gov search.
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- Conditions
- Smallpox
- Interventions
- MVA Smallpox Vaccine, Placebo, Live vaccinia virus vaccine
- Biological · Other
- Lead sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
- NIH
- Eligibility
- 18 Years to 38 Years
- Enrollment
- 72 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2005 – 2008
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Smallpox
- Interventions
- MVA Smallpox Vaccine
- Biological
- Lead sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
- NIH
- Eligibility
- 18 Years to 40 Years
- Enrollment
- 435 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2013 – 2015
- U.S. locations
- 6
- States / cities
- Decatur, Georgia • Iowa City, Iowa • Baltimore, Maryland + 3 more
- Conditions
- Healthy
- Interventions
- Modified Vaccinia Virus Ankara TBC-MVA
- Drug
- Lead sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
- NIH
- Eligibility
- Not listed
- Enrollment
- 80 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2003 – 2006
- U.S. locations
- 1
- States / cities
- Bethesda, Maryland
- Conditions
- Smallpox
- Interventions
- Cell-Cultured Smallpox Vaccine compared to Dryvax®
- Biological
- Lead sponsor
- DynPort Vaccine Company LLC, A GDIT Company
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 350 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2002 – 2003
- U.S. locations
- 1
- States / cities
- Lexington, Kentucky
- Conditions
- Smallpox
- Interventions
- LF formulation of IMVAMUNE®, FD formulation of IMVAMUNE®
- Biological
- Lead sponsor
- Bavarian Nordic
- Industry
- Eligibility
- 18 Years to 55 Years
- Enrollment
- 651 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2013 – 2014
- U.S. locations
- 3
- States / cities
- South Miami, Florida • Lenexa, Kansas • Lexington, Kentucky
- Conditions
- Smallpox
- Interventions
- IMVAMUNE®
- Biological
- Lead sponsor
- Bavarian Nordic
- Industry
- Eligibility
- 18 Years to 45 Years
- Enrollment
- 87 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2017
- U.S. locations
- 10
- States / cities
- Birmingham, Alabama • Little Rock, Arkansas • San Francisco, California + 7 more
- Conditions
- Smallpox
- Interventions
- Not listed
- Lead sponsor
- Emergent BioSolutions
- Industry
- Eligibility
- 17 Years and older
- Enrollment
- 14,108 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2008 – 2015
- U.S. locations
- 4
- States / cities
- Twentynine Palms, California • Fort Campbell North, Kentucky • Fort Bliss, Texas + 1 more
- Conditions
- Atopic Dermatitis
- Interventions
- IMVAMUNE
- Biological
- Lead sponsor
- Bavarian Nordic
- Industry
- Eligibility
- 18 Years to 40 Years
- Enrollment
- 632 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2006 – 2010
- U.S. locations
- 15
- States / cities
- Tucson, Arizona • Hot Springs, Arkansas • Garden Grove, California + 11 more
- Conditions
- HIV Infections
- Interventions
- IMVAMUNE (MVA-BN)
- Biological
- Lead sponsor
- Bavarian Nordic
- Industry
- Eligibility
- 18 Years to 55 Years
- Enrollment
- 151 participants
- Timeline
- Started 2005
- U.S. locations
- 5
- States / cities
- Indianapolis, Indiana • Lexington, Kentucky • St Louis, Missouri + 2 more
- Conditions
- Smallpox
- Interventions
- Vaccinia virus: ACAM2000 smallpox vaccine, vaccinia virus (calf lymph): Dryvax
- Biological
- Lead sponsor
- Emergent BioSolutions
- Industry
- Eligibility
- 18 Years to 29 Years
- Enrollment
- 353 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2003
- U.S. locations
- 4
- States / cities
- Orlando, Florida • Lenexa, Kansas • Springfield, Missouri + 1 more
- Conditions
- HIV Infections
- Interventions
- IMVAMUNE (MVA-BN)
- Biological
- Lead sponsor
- Bavarian Nordic
- Industry
- Eligibility
- 18 Years to 55 Years
- Enrollment
- 581 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2006 – 2009
- U.S. locations
- 34
- States / cities
- Birmingham, Alabama • Little Rock, Arkansas • Burbank, California + 29 more
- Conditions
- Smallpox
- Interventions
- ACAM2000 Smallpox Vaccine, Vaccinia virus (calf lymph) smallpox vaccine: Dryvax®
- Biological
- Lead sponsor
- Emergent BioSolutions
- Industry
- Eligibility
- 28 Years and older
- Enrollment
- 357 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2003
- U.S. locations
- 3
- States / cities
- Lenexa, Kansas • Springfield, Missouri • Pawtucket, Rhode Island
- Conditions
- Smallpox
- Interventions
- MVA Smallpox Vaccine, Placebo
- Biological · Other
- Lead sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
- NIH
- Eligibility
- 18 Years to 38 Years
- Enrollment
- 91 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2009 – 2011
- U.S. locations
- 2
- States / cities
- Iowa City, Iowa • St Louis, Missouri
- Conditions
- Smallpox
- Interventions
- Not listed
- Lead sponsor
- Emergent BioSolutions
- Industry
- Eligibility
- 17 Years and older
- Enrollment
- 5,001 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2009 – 2012
- U.S. locations
- 1
- States / cities
- Alexandria, Virginia
- Conditions
- Smallpox
- Interventions
- MVA Smallpox Vaccine
- Biological
- Lead sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
- NIH
- Eligibility
- 18 Years to 38 Years
- Enrollment
- 523 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2010 – 2011
- U.S. locations
- 8
- States / cities
- Decatur, Georgia • Iowa City, Iowa • Baltimore, Maryland + 4 more
- Conditions
- Smallpox
- Interventions
- IMVAMUNE
- Biological
- Lead sponsor
- Bavarian Nordic
- Industry
- Eligibility
- 56 Years to 80 Years
- Enrollment
- 120 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2009 – 2010
- U.S. locations
- 4
- States / cities
- Orlando, Florida • Iowa City, Iowa • Lexington, Kentucky + 1 more
- Conditions
- Smallpox
- Interventions
- Live vaccinia virus vaccine, MVA Smallpox Vaccine, Placebo
- Biological · Other
- Lead sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
- NIH
- Eligibility
- 18 Years to 32 Years
- Enrollment
- 91 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2004 – 2007
- U.S. locations
- 1
- States / cities
- St Louis, Missouri
- Conditions
- Smallpox
- Interventions
- Live vaccinia virus vaccine, MVA Smallpox Vaccine, Placebo
- Biological · Other
- Lead sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
- NIH
- Eligibility
- 18 Years to 38 Years
- Enrollment
- 226 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2007 – 2009
- U.S. locations
- 7
- States / cities
- Iowa City, Iowa • Baltimore, Maryland • St Louis, Missouri + 4 more
- Conditions
- Smallpox
- Interventions
- IMVAMUNE®, Placebo
- Biological · Other
- Lead sponsor
- Bavarian Nordic
- Industry
- Eligibility
- 18 Years to 40 Years
- Enrollment
- 4,005 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2013 – 2014
- U.S. locations
- 34
- States / cities
- Birmingham, Alabama • Anaheim, California • Los Angeles, California + 31 more
- Conditions
- Myocarditis, Pericarditis
- Interventions
- Not listed
- Lead sponsor
- Emergent BioSolutions
- Industry
- Eligibility
- 17 Years and older
- Enrollment
- 24 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2011 – 2019
- U.S. locations
- 1
- States / cities
- San Diego, California
- Conditions
- Smallpox
- Interventions
- Tecovirimat, Smallpox and Mpox Vaccine, Placebo
- Drug · Other
- Lead sponsor
- SIGA Technologies
- Industry
- Eligibility
- 18 Years to 42 Years
- Enrollment
- 100 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2022 – 2027
- U.S. locations
- 2
- States / cities
- Omaha, Nebraska • Columbus, Ohio
- Conditions
- Smallpox
- Interventions
- FD MVA-BN
- Biological
- Lead sponsor
- Bavarian Nordic
- Industry
- Eligibility
- 18 Years to 45 Years
- Enrollment
- 1,129 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019 – 2020
- U.S. locations
- 12
- States / cities
- Birmingham, Alabama • Melbourne, Florida • Peoria, Illinois + 8 more
- Conditions
- Smallpox
- Interventions
- ACAM2000® smallpox vaccine
- Biological
- Lead sponsor
- Emergent BioSolutions
- Industry
- Eligibility
- 17 Years and older
- Enrollment
- 897,227 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2008 – 2017
- U.S. locations
- 4
- States / cities
- Twentynine Palms, California • Fort Campbell North, Kentucky • Fort Bliss, Texas + 1 more