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Showing 97–120 of 151 matching trials from the local directory fallback.
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Center for Research and Education on Aging and Technology Enhancement - CREATE V - Project 2

NCT07485712
Conditions
Mild Cognitive Impairment
Interventions
Project 2, Phase 2: Intelligent Adaptive System
Behavioral
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
60 Years and older
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
3
States / cities
Tallahassee, Florida • Champaign, Illinois • New York, New York
Conditions
Type 2 Diabetes
Interventions
Adaptive dietary intervention (GEM), Continuous Glucose Monitoring (CGM)
Behavioral · Device
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2028
U.S. locations
1
States / cities
New York, New York
Conditions
Health Risk Behaviors
Interventions
Adapted W2W, Waitlist Control
Behavioral
Lead sponsor
Laneshia Conner
Other
Eligibility
50 Years and older · Female only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2030
U.S. locations
1
States / cities
Lexington, Kentucky
Conditions
Adolescent Mental Health, Depressive Symptoms, Suicidal Ideation
Interventions
Adapted Brief Interpersonal Psychotherapy for Adolescents (IPT-A LAZOS), Usual Community Center Services
Behavioral · Other
Lead sponsor
Boston College
Other
Eligibility
12 Years to 17 Years
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Chestnut Hill, Massachusetts
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Optimization of Adaptive Rowing Seating

NCT07099625
Conditions
Cerebrovascular Accident With Associated Sequelae, Neurodegenerative Disorders, Spinal Cord Diseases, Spinal Cord Injuries
Interventions
Adaptive Indoor Rowing Seat, Paddle Sport adaptive seating system
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
2
States / cities
Minneapolis, Minnesota • Cleveland, Ohio
Not yet recruiting Not applicable Interventional

Culturally Adapted Contingency Management

NCT07443332
Conditions
Stimulant Use Disorders
Interventions
Basic Contingency Management (CM), Cultually Adapted Contingency Management (CM)
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 65 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2028 – 2030
U.S. locations
1
States / cities
New Haven, Connecticut
Not yet recruiting Not applicable Interventional

CBITS-RTM Pilot Study

NCT07682441
Conditions
PTSD - Post Traumatic Stress Disorder, Substance Use
Interventions
Adapted Cognitive Behavioral Intervention for Trauma in Schools (CBITS) with a Racial Trauma Module (RTM)
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
13 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
San Francisco, California
Conditions
Diabetes, Food Security, Nutrition Security, Physical Activity
Interventions
Culturally-tailored, enhanced adaption of Diabetes Prevention Program
Behavioral
Lead sponsor
University of Missouri, Kansas City
Other
Eligibility
18 Years and older
Enrollment
408 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2031
U.S. locations
1
States / cities
Kansas City, Missouri
Not yet recruiting Not applicable Interventional

Substance Use in Assault-Injured Young Adults

NCT07070414
Conditions
Alcohol Misuse, Cannabis Misuse
Interventions
Brief Negotiation Interview intervention (BNI) (adapted)
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 25 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2028
U.S. locations
1
States / cities
New Haven, Connecticut
Conditions
Healthy Young Adults
Interventions
Adaptive Torque Control System for Ankle Exoskeleton
Device
Lead sponsor
University of Nebraska
Other
Eligibility
19 Years to 35 Years
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Omaha, Nebraska
Conditions
Amputation
Interventions
Fillauer Motion Foot SLX, Fillauer Slope Adaptive Foot
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 89 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Minneapolis, Minnesota
Conditions
Firearm Injury, Firearm Safety, Suicide
Interventions
Adapted S.A.F.E. Firearm, Implementation bundle
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
7,200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
2
States / cities
Philadelphia, Pennsylvania
Not yet recruiting Not applicable Interventional

ADINA vs. High Flow Nasal Cannula Comparison Study

NCT03171129
Conditions
Respiratory Distress Neonatal
Interventions
Adaptive Dynamic Inspiratory Nasal Apparatus, High flow Nasal Canula
Device
Lead sponsor
Loma Linda University
Other
Eligibility
23 Weeks to 40 Weeks
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Loma Linda, California
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Intervention to Reduce Implicit Bias in Pharmacies

NCT06487351
Conditions
Bias, Implicit, HIV, Pre-exposure Prophylaxis
Interventions
The NIH Implicit Bias course, The adapted PHBI
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2027 – 2029
U.S. locations
1
States / cities
Boston, Massachusetts
Not yet recruiting Not applicable Interventional

Adaptive Cell Phone Support (ACPS)

NCT07064824
Conditions
Medication Adherence
Interventions
Adaptive Cell Phone Support, Automated Text Reminders, Computer-Delivered Cell Phone Support
Behavioral
Lead sponsor
Children's Hospital Los Angeles
Other
Eligibility
15 Years to 20 Years
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2030
U.S. locations
1
States / cities
Los Angeles, California
Active, not recruiting No phase listed Observational

ALTERRA Post-Approval Study

NCT05378386
Conditions
Complex Congenital Heart Defect, Pulmonary Regurgitation, Pulmonary Valve Insufficiency, RVOT Anomaly, Tetralogy of Fallot
Interventions
Edwards Alterra Adaptive Prestent with SAPIEN 3 Transcatheter Pulmonary Valve System
Device
Lead sponsor
Edwards Lifesciences
Industry
Eligibility
Not listed
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2035
U.S. locations
23
States / cities
Birmingham, Alabama • Little Rock, Arkansas • Los Angeles, California + 18 more
Conditions
Cognitive Decline, Hypertension
Interventions
Stepped-care protocol adapted from the SPRINT intensive-treatment algorithm
Behavioral
Lead sponsor
Tulane University
Other
Eligibility
40 Years and older
Enrollment
1,306 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2026
U.S. locations
1
States / cities
New Orleans, Louisiana
Conditions
Parkinson's Disease (PD)
Interventions
adaptive DBS (aDBS)
Device
Lead sponsor
University of Colorado, Denver
Other
Eligibility
45 Years to 75 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Aurora, Colorado
Active, not recruiting No phase listed Observational

INFINITY™ With ADAPTIS™ Technology Study

NCT04594993
Conditions
Arthritis, Rheumatoid
Interventions
INFINITY™ with ADAPTIS™ Technology Total Ankle System
Device
Lead sponsor
Stryker Trauma and Extremities
Industry
Eligibility
22 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2035
U.S. locations
13
States / cities
Gilbert, Arizona • Rancho Mirage, California • Aurora, Colorado + 10 more
Active, not recruiting Not applicable Interventional

Anticipating Decline and Providing Therapy

NCT06182995
Conditions
Cognitive Impairment, Cognitive Impairment, Mild, Critical Illness, Dementia, Post ICU Syndrome
Interventions
Anticipating Decline and Providing Therapy (ADAPT), Usual Care post-Intensive Care Unit (ICU)
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
60 Years and older
Enrollment
109 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Conditions
Autism
Interventions
Adapted RUBI-Telehealth
Behavioral
Lead sponsor
Baylor University
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Waco, Texas
Conditions
Concentric Hypertrophy, Heart Failure With Preserved Ejection Fraction
Interventions
Pacemaker PLR + TRT ON, Pacemaker non-pacing mode or an exertional rate-adaptive pacing mode with no planned pacing at rest.
Device
Lead sponsor
Medtronic Cardiac Rhythm and Heart Failure
Industry
Eligibility
18 Years and older
Enrollment
105 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
8
States / cities
Naples, Florida • O'Fallon, Illinois • Springfield, Illinois + 5 more
Conditions
HIV Infection Primary
Interventions
an adaptation of the iENGAGE
Behavioral
Lead sponsor
Florida International University
Other
Eligibility
18 Years and older
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Miami, Florida
Conditions
Cancer of the Prostate, Prostate Cancer
Interventions
Adaptive stereotactic body radiotherapy, Androgen deprivation therapy, Ethos Varian treatment system
Radiation · Drug · Device
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older · Male only
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2030
U.S. locations
1
States / cities
St Louis, Missouri