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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: AF ablation Clear all
Active, not recruiting No phase listed Observational

SPHERE Per-AF Post-Approval Study

NCT06858306
View directory record Official record
Conditions
Persistent Atrial Fibrillation
Interventions
Sphere-9™ Catheter and Affera™ Ablation System
Device
Lead sponsor
Medtronic Cardiac Ablation Solutions
Industry
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
14
States / cities
Birmingham, Alabama • Sarasota, Florida • Atlanta, Georgia + 11 more
Source: ClinicalTrials.gov public record
Updated Jun 17, 2026 · Synced Sep 12, 2026, 2:22 AM EDT
Completed Phase 3 Interventional

Effect of Amiodarone on the Procedure Outcome in Long-standing Persistent Atrial Fibrillation Undergoing Pulmonary Vein Antral Isolation

NCT01173809
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Amiodarone
Drug
Lead sponsor
Texas Cardiac Arrhythmia Research Foundation
Other
Eligibility
18 Years to 75 Years
Enrollment
176 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Aug 20, 2014 · Synced Sep 12, 2026, 2:22 AM EDT
Completed Not applicable Interventional

Timing of Direct Current Cardioversion (DCC) in Patients Undergoing Ablation of Persistent/Permanent Atrial Fibrillation

NCT02429648
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
DCC first then PVI, PVI then DCC after
Procedure
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2015
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 9, 2017 · Synced Sep 12, 2026, 2:22 AM EDT
Recruiting No phase listed Observational

Real-world Experience of Catheter Ablation for the Treatment of Arrhythmias

NCT04088071
View directory record Official record
Conditions
Paroxysmal Atrial Fibrillation, Persistent Atrial Fibrillation, Ventricular Arrhythmia
Interventions
Catheter ablation
Device
Lead sponsor
Heart Rhythm Clinical and Research Solutions, LLC
Other
Eligibility
18 Years and older
Enrollment
20,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2028
U.S. locations
68
States / cities
Birmingham, Alabama • Mobile, Alabama • Chandler, Arizona + 61 more
Source: ClinicalTrials.gov public record
Updated Jul 8, 2026 · Synced Sep 12, 2026, 2:22 AM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

CARTO® 3 System and Real Time Intracardiac Ultrasound

NCT01716663
View directory record Official record
Conditions
Atrial Fibrillation, Paroxysmal AF
Interventions
Catheter Ablation
Device
Lead sponsor
Biosense Webster, Inc.
Industry
Eligibility
18 Years and older
Enrollment
234 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
26
States / cities
Phoenix, Arizona • Scottsdale, Arizona • Santa Barbara, California + 23 more
Source: ClinicalTrials.gov public record
Updated Nov 30, 2014 · Synced Sep 12, 2026, 2:22 AM EDT
Active, not recruiting No phase listed Observational

Phase-Aligned Atrial Fibrillation Mapping

NCT06892561
View directory record Official record
Conditions
Atrial Fibrillation (AF)
Interventions
Not listed
Lead sponsor
Larisa Tereshchenko, MD, PhD
Other
Eligibility
18 Years to 89 Years
Enrollment
336 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 30, 2026 · Synced Sep 12, 2026, 2:22 AM EDT
Completed Phase 4 Interventional Results available

Selective Complex Fractionated Atrial Electrograms (CFAE) Targeting for Atrial Fibrillation

NCT00926783
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
CFAE ablation
Procedure
Lead sponsor
Biosense Webster, Inc.
Industry
Eligibility
18 Years and older
Enrollment
86 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
2
States / cities
Maywood, Illinois • Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 9, 2014 · Synced Sep 12, 2026, 2:22 AM EDT
Withdrawn No phase listed Observational

PVI Using Cryoablation Alone in Paroxysmal AF Patients Converted From Persistent AF With Dofetilide

NCT01877486
View directory record Official record
Conditions
Paroxysmal Atrial Fibrillation, Persistent Atrial Fibrillation
Interventions
Ablation
Procedure
Lead sponsor
University of Rochester
Other
Eligibility
18 Years to 80 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016
U.S. locations
1
States / cities
Ridgewood, New Jersey
Source: ClinicalTrials.gov public record
Updated Oct 3, 2016 · Synced Sep 12, 2026, 2:22 AM EDT
Active, not recruiting Not applicable Interventional

Pulsed-Field Ablation With/Without Electrogram Mapping

NCT07541989
View directory record Official record
Conditions
Non-paroxysmal Atrial Fibrillation
Interventions
PFA-based PVI+PWI plus adjunctive ablation guided by Electrogram Mapping of Key Substrates, PFA-based PVI+PWI alone
Procedure
Lead sponsor
Xu Liu
Other
Eligibility
18 Years to 80 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Apr 20, 2026 · Synced Sep 12, 2026, 2:22 AM EDT
Recruiting Not applicable Interventional

Medtronic Terminate AF Study

NCT03546374
View directory record Official record
Conditions
Persistent Atrial Fibrillation, Longstanding Persistent Atrial Fibrillation
Interventions
Surgical Ablation, Cardioblate and Cryoflex hand held devices
Procedure · Device
Lead sponsor
Medtronic Cardiac Surgery
Industry
Eligibility
18 Years and older
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2026
U.S. locations
15
States / cities
Palo Alto, California • St. Helena, California • Hartford, Connecticut + 11 more
Source: ClinicalTrials.gov public record
Updated May 13, 2026 · Synced Sep 12, 2026, 2:22 AM EDT
Completed Not applicable Interventional Results available

TactiCath Contact Force Ablation Catheter Study for Atrial Fibrillation

NCT01278953
View directory record Official record
Conditions
Paroxysmal Atrial Fibrillation
Interventions
Catheter ablation to treat paroxysmal atrial fibrillation
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 20, 2019 · Synced Sep 12, 2026, 2:22 AM EDT
Completed No phase listed Observational

Role of Cardiac Biomarkers in Prediction of Outcome in Atrial Fibrillation Patients Undergoing Catheter Ablation

NCT02208102
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Radio-frequency catheter ablation
Procedure
Lead sponsor
Texas Cardiac Arrhythmia Research Foundation
Other
Eligibility
50 Years to 75 Years
Enrollment
155 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Oct 18, 2017 · Synced Sep 12, 2026, 2:22 AM EDT
Active, not recruiting Early Phase 1 Interventional

Efficacy of Aldosterone Antagonist Therapy for Prevention of New Atrial Fibrillation

NCT03929718
View directory record Official record
Conditions
AFib
Interventions
Spironolactone, No Spironolactone
Drug
Lead sponsor
Piedmont Healthcare
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2027
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated May 28, 2025 · Synced Sep 12, 2026, 2:22 AM EDT
Recruiting No phase listed Observational

EXercise Cardiac Magnetic Resonance Assessment of Left Atrial Mechanics Following Ablation

NCT06212791
View directory record Official record
Conditions
Paroxysmal Atrial Fibrillation
Interventions
Self- Report Evaluation-Duke Activity Status Index, Self- Report Evaluation Atrial Fibrillation Effect on Quality of Life Questionnaire, Cardiopulmonary exercise test (CPET), Transthoracic echocardiogram, Ambulatory cardiac rhythm assessment, Cardiovascular magnetic resonance (CMR)
Behavioral · Diagnostic Test
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Mar 11, 2026 · Synced Sep 12, 2026, 2:22 AM EDT
Recruiting Not applicable Interventional

Artificial Intelligence Mapping and Ablation of Non-Pulmonary Vein Electrical Drivers of AF Study

NCT06935591
View directory record Official record
Conditions
Atrial Fibrillation (AF)
Interventions
Pulmonary Vein Isolation, vMap® + Pulmonary Vein Isolation
Procedure · Device
Lead sponsor
Vektor Medical
Industry
Eligibility
22 Years and older
Enrollment
423 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
12
States / cities
Jonesboro, Arkansas • Clearwater, Florida • Jacksonville, Florida + 9 more
Source: ClinicalTrials.gov public record
Updated Mar 15, 2026 · Synced Sep 12, 2026, 2:22 AM EDT
Recruiting Not applicable Interventional

Endocardial Mapping With the CoreMap EP Mapping System

NCT06529978
View directory record Official record
Conditions
Persistent Atrial Fibrillation
Interventions
CoreMap EP Mapping System Mapping, CoreMap EP Mapping System Map-Guided Ablation
Device
Lead sponsor
CoreMap Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
245 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
3
States / cities
Naples, Florida • Burlington, Vermont • Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Jul 13, 2026 · Synced Sep 12, 2026, 2:22 AM EDT
Terminated Phase 4 Interventional Results available

Effects of Fish Oil on Post Ablation Arrhythmias

NCT00791089
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
LOVAZA Omega 3-acid ethyl esters, LOVAZA, placebo
Drug · Other
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 70 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 11, 2017 · Synced Sep 12, 2026, 2:22 AM EDT
Completed Not applicable Interventional

Evaluation of Conventional Ablation With or Without Focal Impulse and Rotor Modulation to Eliminate Human AF

NCT02456233
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Conventional AF Ablation with PVI, FIRM-guided ablation plus PVI
Procedure
Lead sponsor
Stanford University
Other
Eligibility
22 Years and older
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2025
U.S. locations
2
States / cities
San Diego, California • Stanford, California
Source: ClinicalTrials.gov public record
Updated Mar 3, 2025 · Synced Sep 12, 2026, 2:22 AM EDT
Not listed No phase listed Observational

Does Atrial Fibrillation (AF) Termination Without Additional Ablation Influence Outcome?

NCT01696344
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
PVAI, PVAI + ablation of extraPV triggers
Procedure
Lead sponsor
Texas Cardiac Arrhythmia Research Foundation
Other
Eligibility
18 Years to 80 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2019
U.S. locations
2
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Apr 9, 2019 · Synced Sep 12, 2026, 2:22 AM EDT
Completed Phase 4 Interventional Results available

Use of Dapagliflozin to Reduce Burden of Atrial Fibrillation in Patients Undergoing Catheter Ablation of Symptomatic Atrial Fibrillation

NCT04792190
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
dapagliflozin, Placebo
Drug
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
3
States / cities
Portland, Maine • Detroit, Michigan • Rochester, New York
Source: ClinicalTrials.gov public record
Updated Dec 3, 2024 · Synced Sep 12, 2026, 2:22 AM EDT
Completed Not applicable Interventional Results available

CONVERGE - Epi/Endo Ablation For Treatment of Persistent Atrial Fibrillation(AF)

NCT01984346
View directory record Official record
Conditions
Persistent Atrial Fibrillation
Interventions
AtriCure EPi-Sense-AF Guided Coagulation System with VisiTrax, Endocardial RF Catheter ablation using Open Irrigated-tip RF Abaltion Catheter with unidirectional or bidirectional steering
Device
Lead sponsor
AtriCure, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
170 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2023
U.S. locations
25
States / cities
Birmingham, Alabama • Huntsville, Alabama • Denver, Colorado + 22 more
Source: ClinicalTrials.gov public record
Updated Nov 12, 2023 · Synced Sep 12, 2026, 2:22 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Atrial Fibrillation Ablation on Gastric Motility "The AF Gut Study"

NCT01396356
View directory record Official record
Conditions
Atrial Fibrillation Ablation Procedure
Interventions
GI procedures
Procedure
Lead sponsor
Dhanunjaya Lakkireddy, MD, FACC
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Jan 9, 2013 · Synced Sep 12, 2026, 2:22 AM EDT
Completed No phase listed Observational

Prospective Study to Validate Ablation Parameters with MRI Based Scar for Left Atrial Ablation

NCT04363307
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
AF Ablation, MRI
Device
Lead sponsor
Ravi Ranjan
Other
Eligibility
18 Years and older
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Oct 31, 2024 · Synced Sep 12, 2026, 2:22 AM EDT
Terminated Phase 3 Interventional Results available

Pivotal Clinical Study of Endoscopic Ablation for Atrial Fibrillation (AF) in Patients That Have Failed Drugs

NCT00477230
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Endoscopic Ablation System, Standard Anti-arrhythmic Drug (AAD) Therapy
Device · Drug
Lead sponsor
CardioFocus
Industry
Eligibility
18 Years to 80 Years
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
18
States / cities
Scottsdale, Arizona • Sacramento, California • San Francisco, California + 15 more
Source: ClinicalTrials.gov public record
Updated Jun 26, 2012 · Synced Sep 12, 2026, 2:22 AM EDT