- Conditions
- Lower Limb Injury, Ankle Foot Orthosis (AFO), Lower Limb Trauma
- Interventions
- Advanced Ankle Foot Orthosis (AFO), Conventional Ankle Foot Orthosis (AFO)
- Device
- Lead sponsor
- University of South Florida
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 75 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2029
- U.S. locations
- 3
- States / cities
- Tampa, Florida • New York, New York
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Showing 1–24
of 39
matching trials from the live ClinicalTrials.gov search.
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- Conditions
- Foot Injuries and Disorders
- Interventions
- Reaktiv AFO, PhatBrace AFO
- Device
- Lead sponsor
- Jason Wilken
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 54 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2023
- U.S. locations
- 3
- States / cities
- Iowa City, Iowa • Bethesda, Maryland • Minneapolis, Minnesota
- Conditions
- Stroke
- Interventions
- WalkAide, Ankle-Foot Orthosis (AFO)
- Device · Other
- Lead sponsor
- Innovative Neurotronics
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 495 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2013
- U.S. locations
- 29
- States / cities
- Loma Linda, California • Los Angeles, California • Pomona, California + 25 more
- Conditions
- Healthy, Ankle Foot Orthosis (AFO), Peripheral Neuropathy
- Interventions
- Carbon Fiber Custom Dynamic Orthosis (CDO)
- Device
- Lead sponsor
- University of Iowa
- Other
- Eligibility
- 18 Years to 90 Years
- Enrollment
- 60 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2024 – 2026
- U.S. locations
- 1
- States / cities
- Iowa City, Iowa
- Conditions
- Gait
- Interventions
- standard of care treatment, Ankle Flexion Dynasplint
- Other · Device
- Lead sponsor
- Dynasplint Systems, Inc.
- Industry
- Eligibility
- 1 Year to 18 Years
- Enrollment
- 10 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- Started 2010
- U.S. locations
- 2
- States / cities
- Columbus, Ohio • Lubbock, Texas
- Conditions
- Foot Drop, Acute Lymphoblastic Leukemia
- Interventions
- AFO Device
- Device
- Lead sponsor
- St. Jude Children's Research Hospital
- Other
- Eligibility
- 6 Years to 18 Years
- Enrollment
- 2 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2011
- U.S. locations
- 1
- States / cities
- Memphis, Tennessee
- Conditions
- Traumatic Lower Limb Injury
- Interventions
- Carbon Fiber Custom Dynamic Orthosis (CDO)
- Device
- Lead sponsor
- University of Iowa
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2026
- U.S. locations
- 1
- States / cities
- Iowa City, Iowa
- Conditions
- Stroke, CVA, Hemiplegia, Hemiparesis, Foot Drop
- Interventions
- Posterior Leaf spring AFO, Double adjustable AFO
- Device
- Lead sponsor
- Texas Woman's University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 23 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2018
- U.S. locations
- 1
- States / cities
- Frisco, Texas
- Conditions
- Parkinson's Disease
- Interventions
- Ankle foot orthosis
- Device
- Lead sponsor
- University of Texas Southwestern Medical Center
- Other
- Eligibility
- 50 Years to 75 Years
- Enrollment
- 4 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2013
- U.S. locations
- 1
- States / cities
- Dallas, Texas
- Conditions
- Ankle Foot Orthosis (AFO), Stroke Patients, Post-Stroke Hemiparesis
- Interventions
- Pre-fabricated (PF) ankle-foot orthosis (AFO), Carbon-strut (CS) ankle-foot orthosis (AFO), Multifunctional articulating (MA) ankle-foot orthosis (AFO)
- Device
- Lead sponsor
- University of Texas at Austin
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 120 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2027
- U.S. locations
- 4
- States / cities
- Downey, California • Jacksonville, Florida • Charleston, South Carolina + 1 more
- Conditions
- Foot Injuries and Disorders
- Interventions
- Structure Sensor
- Device
- Lead sponsor
- University of Iowa
- Other
- Eligibility
- 18 Years to 75 Years
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2020 – 2023
- U.S. locations
- 1
- States / cities
- Iowa City, Iowa
- Conditions
- Congenital Talipes Equinovarus
- Interventions
- Ankle Foot Orthosis (AFO)
- Device
- Lead sponsor
- Medical College of Wisconsin
- Other
- Eligibility
- Up to 12 Months
- Enrollment
- 3 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2022
- U.S. locations
- 1
- States / cities
- Milwaukee, Wisconsin
- Conditions
- Walking Aided by a Leg Brace in Stroke Subjects
- Interventions
- ADR™ brace resistance, Conventional brace resistance (using hard stops)
- Device
- Lead sponsor
- Albert Einstein Healthcare Network
- Other
- Eligibility
- 21 Years to 70 Years
- Enrollment
- 5 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2020
- U.S. locations
- 1
- States / cities
- Elkins Park, Pennsylvania
- Conditions
- Ankle Fractures, Post-traumatic Osteoarthritis, Osteoarthritis Ankle
- Interventions
- Carbon Fiber Custom Dynamic Orthosis (CDO)
- Device
- Lead sponsor
- University of Iowa
- Other
- Eligibility
- 18 Years to 65 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2025
- U.S. locations
- 1
- States / cities
- Iowa City, Iowa
- Conditions
- Lower Limb Injury
- Interventions
- Utilization of motorized orthosis
- Device
- Lead sponsor
- Kessler Foundation
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 19 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2027
- U.S. locations
- 1
- States / cities
- West Orange, New Jersey
- Conditions
- Gait Disorders, Neurologic, Parkinson Disease
- Interventions
- Carbon Fiber Ankle Foot Orthosis (AFO), Standardized walking/exercise program
- Device · Other
- Lead sponsor
- University of Texas Southwestern Medical Center
- Other
- Eligibility
- 30 Years to 85 Years
- Enrollment
- 10 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2020
- U.S. locations
- 1
- States / cities
- Dallas, Texas
- Conditions
- Cerebral Palsy
- Interventions
- Flexible orthotic, Standard orthotic
- Device
- Lead sponsor
- Virginia Commonwealth University
- Other
- Eligibility
- 6 Months to 18 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021
- U.S. locations
- 1
- States / cities
- Richmond, Virginia
- Conditions
- Cerebral Palsy
- Interventions
- Smart Ankle-Foot Orthosis, 5-Azacitidine, Placebo
- Device · Drug
- Lead sponsor
- Shirley Ryan AbilityLab
- Other
- Eligibility
- 8 Years to 17 Years
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2030
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Cerebral Palsy
- Interventions
- Differential and adjustable stiffness AFO (DAS-AFO)
- Device
- Lead sponsor
- Northern Arizona University
- Other
- Eligibility
- 8 Years to 35 Years
- Enrollment
- 11 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024
- U.S. locations
- 1
- States / cities
- Flagstaff, Arizona
- Conditions
- Foot Injuries and Disorders
- Interventions
- Structure Sensor, Caliper
- Device
- Lead sponsor
- University of Iowa
- Other
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 30 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019 – 2022
- U.S. locations
- 1
- States / cities
- Iowa City, Iowa
- Conditions
- Stroke
- Interventions
- Smart AFO
- Device
- Lead sponsor
- Orthocare Innovations, LLC
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 50 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2024
- U.S. locations
- 3
- States / cities
- Troy, Michigan • Salt Lake City, Utah • Edmonds, Washington
- Conditions
- Charcot Marie Tooth Disease (CMT)
- Interventions
- Ankle-foot Orthoses
- Device
- Lead sponsor
- Bopha Chrea
- Other
- Eligibility
- 25 Years to 55 Years
- Enrollment
- 66 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2027
- U.S. locations
- 1
- States / cities
- North Liberty, Iowa
- Conditions
- Peripheral Artery Disease
- Interventions
- AFO to improve outcomes
- Device
- Lead sponsor
- University of Minnesota
- Other
- Eligibility
- 40 Years and older
- Enrollment
- 31 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2017
- U.S. locations
- 1
- States / cities
- Missoula, Montana
- Conditions
- Stroke
- Interventions
- WalkAide, AFO
- Device
- Lead sponsor
- Innovative Neurotronics
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 121 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2005 – 2008
- U.S. locations
- 5
- States / cities
- Phoenix, Arizona • San Francisco, California • St Louis, Missouri + 2 more