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ClinicalTrials.gov public records Last synced Sep 7, 2026, 6:52 PM EDT

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Showing 1–24 of 45 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: ASPIRE Clear all
Recruiting No phase listed Observational

DMCRN-02-001: Assessing Pediatric Endpoints in DM1

NCT05224778
View directory record Official record
Conditions
Congenital Myotonic Dystrophy, CDM
Interventions
Not listed
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
Up to 59 Months
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
4
States / cities
Los Angeles, California • Fairway, Kansas • Rochester, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Jun 9, 2026 · Synced Sep 7, 2026, 6:52 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Air Pollution: Strategies for Personalized Intervention to Reduce Exposure

NCT03744871
View directory record Official record
Conditions
Air Pollution
Interventions
N95 Respirator
Other
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 3, 2023 · Synced Sep 7, 2026, 6:52 PM EDT
Completed Phase 3 Interventional

Assessing Screening Plus Brief Intervention's Resulting Efficacy (ASPIRE) to Stop Drug Use

NCT00876941
View directory record Official record
Conditions
Drug Usage, Drug Abuse, Drug Dependence
Interventions
Standard Brief Intervention, Enhanced Brief Intervention, Control: Information and Feedback
Behavioral
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years and older
Enrollment
589 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 1, 2014 · Synced Sep 7, 2026, 6:52 PM EDT
Recruiting Phase 3 Interventional

Testing the Addition of Docetaxel (Chemotherapy) to the Usual Treatment (Hormonal Therapy and Apalutamide) for Metastatic Prostate Cancer, ASPIRE Trial

NCT06931340
View directory record Official record
Conditions
Castration-Sensitive Prostate Carcinoma, Metastatic Prostate Adenocarcinoma, Stage IVB Prostate Cancer AJCC v8
Interventions
Androgen Therapy, Apalutamide, Docetaxel, Computed Tomography, Magnetic Resonance Imaging, Bone Scan, PSMA PET Scan, Biospecimen Collection, Questionnaire Administration
Drug · Procedure · Other
Lead sponsor
Alliance for Clinical Trials in Oncology
Other
Eligibility
18 Years and older · Male only
Enrollment
1,260 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2039
U.S. locations
210
States / cities
Tucson, Arizona • Dublin, California • Fremont, California + 170 more
Source: ClinicalTrials.gov public record
Updated Sep 1, 2026 · Synced Sep 7, 2026, 6:52 PM EDT
Completed Phase 3 Interventional Results available

Aspirin for Exercise in Multiple Sclerosis (ASPIRE)

NCT03824938
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
Aspirin 650mg Oral Capsule, Acetaminophen Tablet 650mg, Placebo
Drug · Other
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 70 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 26, 2023 · Synced Sep 7, 2026, 6:52 PM EDT
Completed Not applicable Interventional Results available

Coaching Veterans to Healthy Weights and Wellness

NCT00967668
View directory record Official record
Conditions
Obesity
Interventions
Small change approach to improve physical activity and diet, MOVE! Usual Care
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years and older
Enrollment
481 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
2
States / cities
Ann Arbor, Michigan • Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 23, 2015 · Synced Sep 7, 2026, 6:52 PM EDT
Not yet recruiting Phase 3 Interventional

Bone Marrow Aspirate Concentrate Versus Triamcinolone Injection For Hip Osteoarthritis

NCT04990128
View directory record Official record
Conditions
Hip Osteoarthritis
Interventions
Aspire Needle + Emcyte PureBMC, Triamcinolone
Combination Product · Drug
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 75 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Weston, Florida
Source: ClinicalTrials.gov public record
Updated Aug 11, 2026 · Synced Sep 7, 2026, 6:52 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Pilot Mammography Reader Study to Assess Breast Cancer Detection in FFDM Plus DBT Versus FFDM Alone

NCT02511730
View directory record Official record
Conditions
Breast Cancer
Interventions
FFDM Plus DBT, FFDM
Device
Lead sponsor
Fujifilm Medical Systems USA, Inc.
Industry
Eligibility
18 Years and older · Female only
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015
U.S. locations
4
States / cities
Scottsdale, Arizona • Rochester, New York • Chapel Hill, North Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Sep 20, 2023 · Synced Sep 7, 2026, 6:52 PM EDT
Completed Not applicable Interventional

ASPIRE: Adapting Self-Blood Pressure Monitoring to Reduce Health Disparities

NCT06175793
View directory record Official record
Conditions
Hypertension
Interventions
ASPIRE Intervention
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 85 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Oak Lawn, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 10, 2025 · Synced Sep 7, 2026, 6:52 PM EDT
Enrolling by invitation Not applicable Interventional

Implementing A Secure Firearm Storage Program in Illinois Health Centers in Partnership With AllianceChicago and the Illinois Primary Health Care Association (COMMUNITY ASPIRE)

NCT06886776
View directory record Official record
Conditions
Suicide
Interventions
Implementation package (training and facilitation)
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
Not listed
Enrollment
1,086 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 19, 2026 · Synced Sep 7, 2026, 6:52 PM EDT
Active, not recruiting Phase 3 Interventional

Safety and Preliminary Efficacy of TSHA-102 Gene Therapy in Pediatric Females Aged >2 to <4 Years With Rett Syndrome

NCT07480564
View directory record Official record
Conditions
Rett Syndrome
Interventions
TSHA-102
Genetic
Lead sponsor
Taysha Gene Therapies, Inc.
Industry
Eligibility
2 Years to 3 Years · Female only
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
3
States / cities
Birmingham, Alabama • Chicago, Illinois • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 18, 2026 · Synced Sep 7, 2026, 6:52 PM EDT
Active, not recruiting Not applicable Interventional

Accountability Support Through Peer-Inspired Relationships and Engagement (ASPIRE) Trial

NCT06617702
View directory record Official record
Conditions
Alcohol Consumption
Interventions
A text message alcohol intervention focused on cognitive, behavioral, and peer influences, A text message alcohol intervention focused on cognitive and behavioral influences
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 25 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Jun 22, 2026 · Synced Sep 7, 2026, 6:52 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Middle and High School Students' Reactions to a Health Interactive Website: ASPIRE Reactions

NCT02469779
View directory record Official record
Conditions
Tobacco Use Cessation, Tobacco Prevention
Interventions
Surveys, ASPIRE Website, ASPIRE Text-Based Website, Follow Up Survey
Behavioral
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
11 Years to 18 Years
Enrollment
700 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2021
U.S. locations
2
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 7, 2021 · Synced Sep 7, 2026, 6:52 PM EDT
Recruiting Not applicable Interventional

Advancing Strategies to Optimize the PerIopeRativE Management of PostOperative Nausea and Vomiting (ASPIRE-PONV) Trial

NCT07152249
View directory record Official record
Conditions
Postoperative Nausea, Postoperative Vomiting
Interventions
AW-D Clinical Decision Support Tool
Other
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
19,480 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jan 11, 2026 · Synced Sep 7, 2026, 6:52 PM EDT
Terminated Phase 3 Interventional

AutoPulse Assisted Prehospital International Resuscitation Trial (ASPIRE)

NCT00120965
View directory record Official record
Conditions
Cardiac Arrest
Interventions
AutoPulse, Manual CPR
Device · Other
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
1,837 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2005
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jan 26, 2011 · Synced Sep 7, 2026, 6:52 PM EDT
Enrolling by invitation Not applicable Interventional

Aspire In Vitro Maturation Study

NCT07789730
View directory record Official record
Conditions
Infertility, In Vitro Maturation of Oocytes, Assisted Reproduction Technologies
Interventions
CAPA-IVM
Device
Lead sponsor
Inception Fertility Research Institute, LLC
Industry
Eligibility
18 Years to 37 Years · Female only
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 26, 2026 · Synced Sep 7, 2026, 6:52 PM EDT
Completed Phase 3 Interventional Results available

Outpatient Study to Evaluate Safety and Effectiveness of the Low Glucose Suspend Feature

NCT01497938
View directory record Official record
Conditions
Type 1 Diabetes
Interventions
Medtronic MMT-754 Veo Insulin pump testing Low Glucose Suspend (LGS) feature, Medtronic (NO LGS FEATURE ) using Paradigm® Revel™2.0 Pump
Device
Lead sponsor
Medtronic MiniMed, Inc.
Industry
Eligibility
16 Years to 70 Years
Enrollment
247 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
17
States / cities
Little Rock, Arkansas • Escondido, California • San Mateo, California + 14 more
Source: ClinicalTrials.gov public record
Updated Mar 16, 2014 · Synced Sep 7, 2026, 6:52 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Multi-Reader Multi-Case Controlled Clinical Trial to Assess the Fujifilm FFDM and DBT Reader Training Program

NCT02685566
View directory record Official record
Conditions
Breast Cancer
Interventions
FFDM Plus DBT, FFDM
Device
Lead sponsor
Fujifilm Medical Systems USA, Inc.
Industry
Eligibility
18 Years and older · Female only
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015
U.S. locations
5
States / cities
Scottsdale, Arizona • Iowa City, Iowa • Rochester, New York + 2 more
Source: ClinicalTrials.gov public record
Updated Sep 20, 2023 · Synced Sep 7, 2026, 6:52 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

A Smoking Prevention Program (ASPIRE) and Mentoring for Preventing Smoking Among High School Youths

NCT04803682
View directory record Official record
Conditions
Healthy Subject
Interventions
Preventive Intervention, Questionnaire Administration
Behavioral
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
13 Years to 18 Years
Enrollment
94 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2021
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 17, 2021 · Synced Sep 7, 2026, 6:52 PM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Fujifilm Feature Comparison Reader Study to Compare Old vs New Processing

NCT03586583
View directory record Official record
Conditions
Breast Cancer
Interventions
FBP, ISR
Device
Lead sponsor
Fujifilm Medical Systems USA, Inc.
Industry
Eligibility
18 Years and older · Female only
Enrollment
600 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Norwalk, Connecticut
Source: ClinicalTrials.gov public record
Updated Sep 20, 2023 · Synced Sep 7, 2026, 6:52 PM EDT
Completed Phase 2 Interventional Results available

Family-Focused, Stress-Reduction Program to Improve the Health Care of Urban Children With Asthma

NCT00384813
View directory record Official record
Conditions
Asthma
Interventions
Project ASPIRE Home-Based Family Intervention, Project ASPIRE Enhanced Treatment As Usual
Behavioral
Lead sponsor
Emory University
Other
Eligibility
8 Years to 13 Years
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
2
States / cities
Atlanta, Georgia • Smyrna, Georgia
Source: ClinicalTrials.gov public record
Updated Jul 27, 2014 · Synced Sep 7, 2026, 6:52 PM EDT
Completed Phase 3 Interventional Results available

Dolutegravir Antiretroviral Strategy to Promote Improvement and Reduce Drug Exposure

NCT02263326
View directory record Official record
Conditions
HIV Infection
Interventions
dolutegravir, lamivudine, Continue current antiretroviral regimen
Drug
Lead sponsor
Babafemi Taiwo
Other
Eligibility
18 Years and older
Enrollment
89 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
7
States / cities
San Diego, California • Atlanta, Georgia • Chicago, Illinois + 4 more
Source: ClinicalTrials.gov public record
Updated Oct 13, 2019 · Synced Sep 7, 2026, 6:52 PM EDT
Completed Not applicable Interventional

Asian American Partnerships in Research and Empowerment (AsPIRE)

NCT03100812
View directory record Official record
Conditions
Hypertensive Heart Disease, Hypertension
Interventions
More intensive CHW Intervention, Less Intensive CHW Intervention
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 25 Years
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2016
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 3, 2017 · Synced Sep 7, 2026, 6:52 PM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

A Multi-Reader Multi-Case Pivotal Trial

NCT02692209
View directory record Official record
Conditions
Breast Cancer
Interventions
FFDM Plus DBT, FFDM Alone
Device
Lead sponsor
Fujifilm Medical Systems USA, Inc.
Industry
Eligibility
18 Years and older · Female only
Enrollment
298 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
5
States / cities
Scottsdale, Arizona • Iowa City, Iowa • Rochester, New York + 2 more
Source: ClinicalTrials.gov public record
Updated Jul 6, 2020 · Synced Sep 7, 2026, 6:52 PM EDT