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ClinicalTrials.gov public records Last synced Sep 5, 2026, 11:02 AM EDT

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Showing 1–24 of 861 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Ablation Procedure Clear all
Recruiting Not applicable Interventional

MRI-guided Transurethral Urethral Ultrasound Ablation for the Treatment of Low to Intermediate Grade Prostate Cancer

NCT05438563
View directory record Official record
Conditions
Prostate Carcinoma, Stage I Prostate Cancer AJCC v8, Stage II Prostate Cancer AJCC v8
Interventions
MRI-Guided Transurethral Ultrasound Ablation, Questionnaire Administration, Digital Rectal Examination, Cystoscopy, Biopsy, Bone Scan, PSMA PET Scan, Multiparametric Magnetic Resonance Imaging
Procedure · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
45 Years to 80 Years · Male only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2028
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 21, 2026 · Synced Sep 5, 2026, 11:02 AM EDT
Terminated Not applicable Interventional Results available

Atrial Pressure Electrophysiology Pilot Study

NCT01845974
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
ThermoCool® SF NAV Catheter, ThermoCool® catheter
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Park Ridge, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 2, 2024 · Synced Sep 5, 2026, 11:02 AM EDT
Completed No phase listed Observational

Redo AF Sub Study (of the Pure EP 2.0 Main Study)

NCT04964440
View directory record Official record
Conditions
Atrial Fibrillation Recurrent
Interventions
Pure-EP
Device
Lead sponsor
BioSig Technologies, Inc.
Industry
Eligibility
18 Years and older
Enrollment
20 participants
Timeline
2021 – 2022
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Feb 10, 2022 · Synced Sep 5, 2026, 11:02 AM EDT
Terminated Phase 2 Interventional

Filgrastim Compared With Sargramostim Plus Chemotherapy, Peripheral Stem Cell Transplantation, and Interferon Alfa in Treating Patients With Multiple Myeloma

NCT00005987
View directory record Official record
Conditions
Multiple Myeloma and Plasma Cell Neoplasm
Interventions
carmustine, cyclophosphamide, dexamethasone, etoposide, filgrastim, mitoxantrone hydrochloride, recombinant interferon alfa, sargramostim, bone marrow ablation with stem cell support, peripheral blood stem cell transplantation, radiation therapy
Drug · Procedure
Lead sponsor
Masonic Cancer Center, University of Minnesota
Other
Eligibility
Up to 70 Years
Enrollment
87 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2003
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Nov 28, 2017 · Synced Sep 5, 2026, 11:02 AM EDT
Completed Not applicable Interventional Results available

Clinical Investigation of the WaveLight® EX500 Excimer Laser

NCT04805593
View directory record Official record
Conditions
Hyperopia, Hyperopic Astigmatism
Interventions
WaveLight EX500 excimer laser system, LASIK
Device · Procedure
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
5
States / cities
Overland Park, Kansas • Kansas City, Missouri • Greensboro, North Carolina + 2 more
Source: ClinicalTrials.gov public record
Updated Aug 20, 2024 · Synced Sep 5, 2026, 11:02 AM EDT
Recruiting Phase 2 Interventional

OPTIMUS PRIME: Safety and Feasibility of OPTune GIO® Integrated With MRI-gUided Laser Ablation Surgery and Pembrolizumab for Recurrent GlIoblastoMa, A randomizEd Trial

NCT06558214
View directory record Official record
Conditions
Recurrent Glioblastoma
Interventions
Pembrolizumab, Optune GIO®, NeuroBlate®
Drug · Device
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 90 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jan 6, 2026 · Synced Sep 5, 2026, 11:02 AM EDT
Completed Not applicable Interventional

Comparison of Treatments for Barrett's Esophagus With High-Grade Dysplasia/Early Adenocarcinoma

NCT01961778
View directory record Official record
Conditions
Barrett's Esophagus
Interventions
Radio-Frequency Ablation, Cryotherapy
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
21 Years to 99 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 11, 2022 · Synced Sep 5, 2026, 11:02 AM EDT
Recruiting Not applicable Interventional

Ventricular Tachycardia Mechanisms

NCT05478213
View directory record Official record
Conditions
Ventricular Tachycardia
Interventions
Monophasic Action Potential (MAP) Catheter
Device
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
3
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jun 29, 2026 · Synced Sep 5, 2026, 11:02 AM EDT
Recruiting Not applicable Interventional

A Randomized Placebo-procedure Controlled Trial of the Enhancor System (PULmonary Artery Denervation) to Evaluate Safety and Efficacy in Patients With Combined Pre- and Post-capillary Pulmonary Hypertension Associated With Left Heart Disease

NCT07214376
View directory record Official record
Conditions
Pulmonary Hypertension, Heart Failure With Reduced Ejection Fraction, Hypertension, Vascular Diseases, Cardiovascular Diseases, Heart Failure, Heart Failure With Preserved Ejection Fraction, Heart Failure With Mid Range Ejection Fraction
Interventions
Pulmonary Artery Denervation (PADN), Sham procedure control
Device
Lead sponsor
Pulnovo Medical, Inc.
Industry
Eligibility
18 Years to 85 Years
Enrollment
750 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
6
States / cities
Tucson, Arizona • Houma, Louisiana • Detroit, Michigan + 3 more
Source: ClinicalTrials.gov public record
Updated Aug 17, 2026 · Synced Sep 5, 2026, 11:02 AM EDT
Completed Not applicable Interventional

MRI Assessment of Arrythmia Ablation Lesions

NCT02761343
View directory record Official record
Conditions
Ventricular Tachycardia, Cardiac Arrhythmia
Interventions
MRI scan
Other
Lead sponsor
Children's National Research Institute
Other
Eligibility
Not listed
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jan 20, 2020 · Synced Sep 5, 2026, 11:02 AM EDT
Completed No phase listed Observational Results available

NAVISTAR® THERMOCOOL® SF Catheter: Observational Study

NCT01585961
View directory record Official record
Conditions
Atrial Fibrillation, Paroxysmal Arrhythmia
Interventions
Catheter Ablation (NAVISTAR® THERMOCOOL® SF Catheter)
Device
Lead sponsor
Biosense Webster, Inc.
Industry
Eligibility
18 Years and older
Enrollment
511 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
45
States / cities
Huntsville, Alabama • Anchorage, Alaska • Phoenix, Arizona + 40 more
Source: ClinicalTrials.gov public record
Updated Jan 25, 2015 · Synced Sep 5, 2026, 11:02 AM EDT
Completed Not applicable Interventional

Radiofrequency Ablation of Papillary Thyroid Microcarcinoma

NCT05132205
View directory record Official record
Conditions
Papillary Thyroid Cancer
Interventions
Radiofrequency Ablation
Procedure
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 100 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 29, 2025 · Synced Sep 5, 2026, 11:02 AM EDT
Not listed Phase 4 Interventional Accepts healthy volunteers

Multi Laser Platform Comparison Study for LASIK

NCT00770094
View directory record Official record
Conditions
Myopia, Astigmatism
Interventions
Excimer Lasers, Excimer Laser for the LASIK procedure, Excimer Laser for LASIK
Device
Lead sponsor
Durrie Vision
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
3
States / cities
Atlanta, Georgia • Edina, Minnesota • McLean, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 5, 2009 · Synced Sep 5, 2026, 11:02 AM EDT
Terminated Not applicable Interventional Results available

The Substrate and Intervention Mechanisms for Persistent Atrial Fibrillation Trial

NCT02918396
View directory record Official record
Conditions
Persistent Atrial Fibrillation
Interventions
Scar-Based Radio-frequency Ablation, Rotor Anchors Radio-frequency Ablation, Conventional PVI by Radio-frequency Ablation
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 3, 2018 · Synced Sep 5, 2026, 11:02 AM EDT
Terminated Phase 4 Interventional Results available

Interventional Cryotherapy for the Eradication of Benign Airway Disease ("ICE the BAD")

NCT00747461
View directory record Official record
Conditions
Lung Diseases, Obstructive, Sarcoidosis, Wegener's Granulomatosis, Rhinoscleroma, Recurrent Respiratory Papillomatosis
Interventions
CryoSpray Ablation
Device
Lead sponsor
CSA Medical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 17, 2015 · Synced Sep 5, 2026, 11:02 AM EDT
Completed No phase listed Observational

Radiofrequency Nerve Ablation Versus Sham to Treat Chronic Low Back Pain Caused by Sacroiliac Joint Dysfunction

NCT01104051
View directory record Official record
Conditions
Sacroiliac Joint Dysfunction
Interventions
Not listed
Lead sponsor
Coastal Orthopedics & Sports Medicine
Other
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
Bradenton, Florida
Source: ClinicalTrials.gov public record
Updated Jul 28, 2015 · Synced Sep 5, 2026, 11:02 AM EDT
Completed Phase 3 Interventional

Ablation of Perimitral Flutter Following Catheter Ablation of Atrial Fibrillation: Impact on Outcomes

NCT01173796
View directory record Official record
Conditions
Atrial Fibrillation, Perimitral Flutter
Interventions
catheter ablation
Procedure
Lead sponsor
Texas Cardiac Arrhythmia Research Foundation
Other
Eligibility
18 Years to 75 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Jul 10, 2012 · Synced Sep 5, 2026, 11:02 AM EDT
Completed Phase 1 Interventional

Ultrasound in Treating Patients With Prostate Cancer Confined to the Prostate

NCT00030290
View directory record Official record
Conditions
Prostate Cancer
Interventions
high-intensity focused ultrasound ablation
Procedure
Lead sponsor
Focus Surgery
Industry
Eligibility
40 Years to 80 Years · Male only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2006
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Jul 9, 2013 · Synced Sep 5, 2026, 11:02 AM EDT
Completed Not applicable Interventional Results available

CONVERGE - Epi/Endo Ablation For Treatment of Persistent Atrial Fibrillation(AF)

NCT01984346
View directory record Official record
Conditions
Persistent Atrial Fibrillation
Interventions
AtriCure EPi-Sense-AF Guided Coagulation System with VisiTrax, Endocardial RF Catheter ablation using Open Irrigated-tip RF Abaltion Catheter with unidirectional or bidirectional steering
Device
Lead sponsor
AtriCure, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
170 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2023
U.S. locations
25
States / cities
Birmingham, Alabama • Huntsville, Alabama • Denver, Colorado + 22 more
Source: ClinicalTrials.gov public record
Updated Nov 12, 2023 · Synced Sep 5, 2026, 11:02 AM EDT
Completed Phase 4 Interventional Results available

Corticosteroid Pulse After Ablation

NCT00807586
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Solumedrol, Placebo
Drug
Lead sponsor
Minneapolis Heart Institute Foundation
Other
Eligibility
18 Years and older
Enrollment
119 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 19, 2019 · Synced Sep 5, 2026, 11:02 AM EDT
Completed Not applicable Interventional

VIVO™ Accuracy Study

NCT03340142
View directory record Official record
Conditions
Premature Ventricular Contraction, Ventricular Tachycardia
Interventions
VIVO™
Device
Lead sponsor
Catheter Precision. Inc.
Industry
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
3
States / cities
Iowa City, Iowa • Baltimore, Maryland • Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Nov 14, 2018 · Synced Sep 5, 2026, 11:02 AM EDT
Withdrawn Phase 2 Interventional

Immune Ablation and Stem Cell Support for Crohn's Disease

NCT00179842
View directory record Official record
Conditions
Crohn Disease
Interventions
Stem Cell Transplant
Procedure
Lead sponsor
Ann & Robert H Lurie Children's Hospital of Chicago
Other
Eligibility
Not listed
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 9, 2025 · Synced Sep 5, 2026, 11:02 AM EDT
Not listed Phase 4 Interventional

Treatment Of Atrial Fibrillation In Preserved Cardiac Function Heart Failure

NCT04160000
View directory record Official record
Conditions
Atrial Fibrillation, Heart Failure, Diastolic Heart Failure
Interventions
Catheter ablation, Rate or Rhythm control antiarrhythmic drugs for atrial fibrillation, Insertion of CardioMems Hemodynamic monitor, Empiric heart failure drug therapy
Device · Drug
Lead sponsor
Electrophysiology Research Foundation
Other
Eligibility
18 Years to 75 Years
Enrollment
360 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
7
States / cities
Flagstaff, Arizona • Jonesboro, Arkansas • Littleton, Colorado + 4 more
Source: ClinicalTrials.gov public record
Updated May 22, 2024 · Synced Sep 5, 2026, 11:02 AM EDT
Completed Not applicable Interventional Results available

Esophageal Temperature Management During Cryo AF Ablation (EnsoETM)

NCT04079634
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Esophageal warming, Control
Device
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 15, 2023 · Synced Sep 5, 2026, 11:02 AM EDT