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ClinicalTrials.gov public records Last synced Nov 13, 2026, 2:36 PM EST

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Showing 49–72 of 414 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Active Transcranial Direct Current Stimulation Clear all
Recruiting Not applicable Interventional

CARED : A Novel Rapid Treatment Paradigm for Depression

NCT07507370
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
Intermittent Theta Burst Stimulation (iTBS), Transcranial Alternating Current Stimulation (tACS), Psychotherapy, Sham (Placebo) Transcranial Alternating Current Stimulation (tACS)
Device · Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 70 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 25, 2026 · Synced Nov 13, 2026, 2:36 PM EST
Completed Early Phase 1 Interventional Results available

Safety of Transcranial Direct Current Stimulation in Pediatric Hemiparesis

NCT01636661
View directory record Official record
Conditions
Hemiparesis
Interventions
tDCS
Device
Lead sponsor
University of Minnesota
Other
Eligibility
8 Years to 17 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Nov 9, 2015 · Synced Nov 13, 2026, 2:36 PM EST
Active, not recruiting Not applicable Interventional

Rapid Entrainment and Signal-guided Neuromodulation for Behavioral Health

NCT07812987
View directory record Official record
Conditions
Anxiety, PTSD, ADHD, Depression Disorders, Post-traumatic Stress, Substance Use, Executive Function, Sleep Disturbance
Interventions
AIP-Informed Integrative Psychotherapy, Transcutaneous Auricular Vagus Nerve Stimulation, Regulated Breathing and Autonomic Regulation, Audiovisual Entrainment, Vibroacoustic Stimulation, Breathwork-Based Auditory Driving Entropy Module (BADEM), Transcranial Electrical Stimulation
Behavioral · Device
Lead sponsor
Tactical Mind Research Coalition, Inc.
Other
Eligibility
18 Years to 70 Years
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Sep 16, 2026 · Synced Nov 13, 2026, 2:36 PM EST
Withdrawn Phase 1 Interventional

Efficacy of TDCS for Treating Working Memory Dysfunction and Depression in Temporal Lobe Epilepsy

NCT02268578
View directory record Official record
Conditions
Epilepsy
Interventions
Transcranial Direct Current Stimulation, Sham Transcranial Direct Current Stimulation
Device · Procedure
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 70 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 15, 2016 · Synced Nov 13, 2026, 2:36 PM EST
Completed Not applicable Interventional Results available

A Novel Neurorehabilitation Approach for Cognitive Aging With HIV

NCT02391311
View directory record Official record
Conditions
HIV, Aging
Interventions
transcranial direct current stimulation (tDCS)
Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
50 Years and older
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated May 15, 2017 · Synced Nov 13, 2026, 2:36 PM EST
Completed Not applicable Interventional Results available

Noninvasive Brain Stimulation on Memory in Individuals With Mild Cognitive Impairment and History of Brain Injury

NCT04504630
View directory record Official record
Conditions
Amnestic Mild Cognitive Impairment, Traumatic Brain Injury, Mild Traumatic Brain Injury
Interventions
High Definition Transcranial Direct Current Stimulation, Sham HD-tDCS
Device
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
50 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jan 13, 2026 · Synced Nov 13, 2026, 2:36 PM EST
Completed Not applicable Interventional Results available

A Study of Home-Delivered Neurostimulation for Migraine

NCT03874351
View directory record Official record
Conditions
Migraine Disorders
Interventions
non-invasive transcranial direct current stimulation (tDCS)
Device
Lead sponsor
MJHS Institute for Innovation in Palliative Care
Other
Eligibility
18 Years to 65 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
2
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 17, 2021 · Synced Nov 13, 2026, 2:36 PM EST
Terminated Not applicable Interventional

Guided Imagery and Transcranial Direct Current Stimulation (tDCS) in Women With Chronic Pelvic Pain

NCT02781103
View directory record Official record
Conditions
Cystitis, Interstitial, Pelvic Pain
Interventions
Guided imagery plus active tDCS, Guided imagery plus Sham tDCS
Other
Lead sponsor
Kenneth M Peters, MD
Other
Eligibility
18 Years to 64 Years · Female only
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Royal Oak, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 2, 2019 · Synced Nov 13, 2026, 2:36 PM EST
Recruiting Not applicable Interventional

Advancing Alzheimer's Care: Home-based tDCS for Affective Symptoms

NCT06801639
View directory record Official record
Conditions
Alzheimer Disease
Interventions
Transcranial direct current stimulation (tDCS), Sham tDCS
Device
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
60 Years to 85 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Feb 11, 2026 · Synced Nov 13, 2026, 2:36 PM EST
Completed Not applicable Interventional Results available

The Effects of CBT and tDCS on Fibromyalgia Patients

NCT02723175
View directory record Official record
Conditions
Fibromyalgia, Chronic Pain
Interventions
Transcranial Direct Current Stimulation
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
21 Years to 85 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Nov 28, 2018 · Synced Nov 13, 2026, 2:36 PM EST
Recruiting Not applicable Interventional Accepts healthy volunteers

Multimodal Investigation of Neural Plasticity

NCT06453980
View directory record Official record
Conditions
Mild Cognitive Impairment
Interventions
sham tDCS, active tDCS
Device
Lead sponsor
University of Michigan
Other
Eligibility
60 Years and older
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 10, 2026 · Synced Nov 13, 2026, 2:36 PM EST
Active, not recruiting Not applicable Interventional

Transcranial Direct Current Stimulation in Conjunction With Individualized Physical Therapy for Individuals With Chronic Knee Pain

NCT06132412
View directory record Official record
Conditions
Knee Pain Chronic
Interventions
transcranial direct current stimulation, physical therapy
Device · Other
Lead sponsor
University of Illinois Chicago
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 11, 2026 · Synced Nov 13, 2026, 2:36 PM EST
Terminated Not applicable Interventional Results available

Transcranial Direct Current Stimulation Therapy for Sleepiness Related to Shift Work Disorder (tDCS-SWORD)

NCT03879044
View directory record Official record
Conditions
Shift-Work Sleep Disorder
Interventions
Transcranial Direct Current Stimulation
Device
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 25, 2021 · Synced Nov 13, 2026, 2:36 PM EST
Completed Not applicable Interventional Accepts healthy volunteers Results available

Modulation of Motor Cortex Excitability by TMS and tDCS (MAGS1)

NCT03481309
View directory record Official record
Conditions
Motor Activity, Motor Neuroplasticity
Interventions
anodal tDCS, cathodal tDCS, sham tDCS
Device
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 35 Years · Male only
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 4, 2021 · Synced Nov 13, 2026, 2:36 PM EST
Recruiting Not applicable Interventional

Neuromodulation-Enhanced Use of RObotic BALANCE Training to Improve Balance Function in Individuals With Stroke

NCT07113041
View directory record Official record
Conditions
Stroke, Stroke (CVA) or Transient Ischemic Attack, Stroke Ischemic, Stroke Gait Rehabilitation, Balance Deficits
Interventions
Combined (Robotic balance training and high-definition transcranial direct current stimulation), Standard of Care Balance Training
Device · Other
Lead sponsor
Kessler Foundation
Other
Eligibility
18 Years to 75 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
West Orange, New Jersey
Source: ClinicalTrials.gov public record
Updated Oct 21, 2026 · Synced Nov 13, 2026, 2:36 PM EST
Completed Not applicable Interventional Accepts healthy volunteers Results available

Single-session tDCS in Cerebral Palsy

NCT03635775
View directory record Official record
Conditions
Cerebral Palsy, Perinatal Stroke, Periventricular Leukomalacia
Interventions
Active tDCS, Sham tDCS
Device
Lead sponsor
University of Minnesota
Other
Eligibility
7 Years to 21 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 13, 2021 · Synced Nov 13, 2026, 2:36 PM EST
Completed Not applicable Interventional Accepts healthy volunteers

The STRENGTHEN Study

NCT06267521
View directory record Official record
Conditions
Cognitive Flexibility, Emotional Regulation
Interventions
Healthy Minds Program, Sham Meditation Didactic Material, Sham Stimulation in Lab, Stimulation in Lab, MRI Scanner
Other · Device
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 50 Years
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Apr 29, 2026 · Synced Nov 13, 2026, 2:36 PM EST
Completed Not applicable Interventional Accepts healthy volunteers Results available

Learning Enhancement Through Neurostimulation in Autism

NCT02998684
View directory record Official record
Conditions
Autism
Interventions
Active Transcranial Direct Current Stimulation, Sham Transcranial Direct Current Stimulation, PEERS Social Skills Training
Device · Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
14 Years to 17 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Sep 4, 2018 · Synced Nov 13, 2026, 2:36 PM EST
Completed Not applicable Interventional Results available

Transcranial Direct Current Stimulation (tDCS)

NCT05524233
View directory record Official record
Conditions
Brain Fog
Interventions
Active Transcranial Direct Stimulation
Device
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 7, 2025 · Synced Nov 13, 2026, 2:36 PM EST
Suspended Not applicable Interventional

Exploring Mechanisms for Neuropsychiatric Symptoms of Parkinson Disease Using Transcranial Direct Current Stimulation

NCT03074812
View directory record Official record
Conditions
Idiopathic Parkinson's Disease, Parkinson Disease, Depression
Interventions
Transcranial Direct Current Stimulation
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 95 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2028
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 23, 2026 · Synced Nov 13, 2026, 2:36 PM EST
Completed Not applicable Interventional

Effects of Transcranial Direct Current Stimulation (tDCS) on Neuropathic Symptoms Due to Burn Injury

NCT01404026
View directory record Official record
Conditions
Pain, Burn Injury
Interventions
Transcranial Direct Current Stimulation (tDCS)
Device
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 64 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 24, 2020 · Synced Nov 13, 2026, 2:36 PM EST
Recruiting Not applicable Interventional Accepts healthy volunteers

Enhancing Attention in Elderly Using a Brain-Computer-Interface

NCT07441122
View directory record Official record
Conditions
Mild Cognitive Impairment (MCI)
Interventions
transcranial electrical stimulation, Mindfulness Meditation
Device · Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years to 90 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
2
States / cities
Austin, Texas • Georgetown, Texas
Source: ClinicalTrials.gov public record
Updated Jul 27, 2026 · Synced Nov 13, 2026, 2:36 PM EST
Recruiting Not applicable Interventional

Neuromodulation + Prolonged Exposure Therapy: Evaluation of a Technology-Enhanced, Integrated Treatment for Pain and PTSD

NCT07116109
View directory record Official record
Conditions
Chronic Pain, Post Traumatic Stress Disorder (PTSD)
Interventions
Transcranial Direct Current Stimulation (tDCS), Massed-Prolonged Exposure (PE), Sham Transcranial Direct Current Stimulation (tDCS)
Device · Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
21 Years and older
Enrollment
146 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
2
States / cities
Charleston, South Carolina • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 3, 2026 · Synced Nov 13, 2026, 2:36 PM EST
Completed Not applicable Interventional

Targeted Noninvasive Brain Stimulation (T-NIBS) to Improve Hand Motor Functions in Acquired Brain Injury

NCT04057105
View directory record Official record
Conditions
Upper Extremity Dysfunction, Traumatic Brain Injury
Interventions
Active High-definition Transcranial Direct Current Stimulation (HD-tDCS), MusicGlove
Device
Lead sponsor
Kessler Foundation
Other
Eligibility
18 Years to 75 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
West Orange, New Jersey
Source: ClinicalTrials.gov public record
Updated Oct 21, 2026 · Synced Nov 13, 2026, 2:36 PM EST