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Conditions: Heart Failure, Heart Failure, Systolic
Interventions: Pharmacist/Cardiologist Virtual Team Digital Consultation; Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years and older
Enrollment: 585 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2030
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Atrial Fibrillation
Interventions: CardiaCare RR2, Sham Device; Device
Lead sponsor: Icahn School of Medicine at Mount Sinai; Other
Eligibility: 18 Years and older
Enrollment: 51 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: New York, New York

Conditions: Bipolar I Disorder
Interventions: Extended-Release Carbamazepine; Drug
Lead sponsor: Validus Pharmaceuticals; Industry
Eligibility: 10 Years to 17 Years
Enrollment: 161 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2007
U.S. locations: 26
States / cities: Altamonte Springs, Florida • Fort Lauderdale, Florida • Gainesville, Florida + 22 more

Conditions: Patellofemoral Pain Syndrome, Knee Pain Chronic, Patellofemoral Syndrome, Anterior Knee Pain Syndrome
Interventions: Psychologically Informed Education, Biomedical Education (Control); Other
Lead sponsor: Nationwide Children's Hospital; Other
Eligibility: 12 Years to 18 Years
Enrollment: 68 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Breast Cancer, Gynecologic Cancer, Cancer-related Cognitive Difficulties
Interventions: Semiconductor embedded headband, Sham Headband; Device
Lead sponsor: University of Utah; Other
Eligibility: 18 Years and older
Enrollment: 7 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Psychosocial, Mind-body
Interventions: Harmony & Health Intervention, Attention Control, Fitbit; Behavioral · Device
Lead sponsor: M.D. Anderson Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2028
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Mild Traumatic Brain Injury, Posttraumatic Stress Disorders, Depression
Interventions: Multifamily Group for mTBI for Couples, Group Health Education (GHE); Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years to 65 Years
Enrollment: 249 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2019
U.S. locations: 3
States / cities: Baltimore, Maryland • New York, New York • The Bronx, New York

Conditions: Pain
Interventions: Percutaneous radiofrequency electrical nerve stimulation, Non-therapeutic stimulation; Device
Lead sponsor: Synaptrix, Inc.; Industry
Eligibility: 21 Years and older
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 5
States / cities: Daphne, Alabama • Williamsville, New York • Chapel Hill, North Carolina + 2 more

Conditions: Physical Activity, Obesity
Interventions: mHealth Physical Activity, Buddy-partnered exercise; Behavioral
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years to 44 Years · Female only
Enrollment: 54 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2016
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Healthy Participants
Interventions: Active eMNS, Sham eMNS; Device
Lead sponsor: Spaulding Rehabilitation Hospital; Other
Eligibility: 18 Years to 40 Years
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Charlestown, Massachusetts

Conditions: Localized Prostate Cancer
Interventions: TOOKAD®; Drug
Lead sponsor: Steba Biotech S.A.; Other
Eligibility: 18 Years and older · Male only
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2030
U.S. locations: 1
States / cities: New York, New York

Conditions: Modeling of Recruitment Curves
Interventions: Algorithm: Uniform Sampling, Algorithm: hbMEP-adaptive algorithm (version 1), Algorithm: hbMEP-adaptive algorithm (version 2), ML-PEST, MagPro X100 Transcranial Magnetic Stimulation, Digitimer DS8R Transcutaneous Electrical stimulation; Other · Device
Lead sponsor: Columbia University; Other
Eligibility: 18 Years to 90 Years
Enrollment: 14 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: New York, New York

Conditions: Pain
Interventions: Forgionei-Barber pressure-pain stimulator, Concentric Exercise, isometric exercise; Device · Other
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 18 Years to 40 Years
Enrollment: 34 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2014
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: HIV Infections, Pregnancy, HIV Seronegativity
Interventions: gp160 Vaccine (MicroGeneSys); Biological
Lead sponsor: National Institute of Allergy and Infectious Diseases (NIAID); NIH
Eligibility: 16 Years to 40 Years · Female only
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Ends 1998
U.S. locations: 2
States / cities: New Haven, Connecticut • Nashville, Tennessee

Conditions: Insomnia, Nightmares, Posttraumatic Stress Disorder
Interventions: Cognitive-Behavioral Insomnia and Nightmare Group; Behavioral
Lead sponsor: Michael E. DeBakey VA Medical Center; Federal
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Stroke
Interventions: D-cycloserine, Placebo, HandMentor Pro; Drug · Other · Device
Lead sponsor: Emory University; Other
Eligibility: 18 Years to 95 Years
Enrollment: 14 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2012
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Metabolism and Nutrition Disorder, Obesity
Interventions: NNC 0070-0002-0182, placebo; Drug
Lead sponsor: Novo Nordisk A/S; Industry
Eligibility: 18 Years to 55 Years
Enrollment: 101 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2008
U.S. locations: 2
States / cities: Evansville, Indiana • Madison, Wisconsin

Conditions: Acute Otitis Externa
Interventions: Ciprodex®, EXL CDOS (Ciprofloxacin 0.3% and Dexamethasone 0.1%) Sterile Otic Suspension; Drug
Lead sponsor: Exela Pharma Sciences, LLC.; Industry
Eligibility: 6 Months and older
Enrollment: 499 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2015
U.S. locations: 46
States / cities: Birmingham, Alabama • Mesa, Arizona • Jonesboro, Arkansas + 36 more

Conditions: Opioid Use Disorder
Interventions: Naltrexone implant, 14.4 grams, Naltrexone implant, 9.6 grams, Extended-release naltrexone injection, 380 mg; Drug
Lead sponsor: Akyso Therapeutics, LLC; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 33 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: Millcreek, Utah

Conditions: Obesity, Insulin Resistance
Interventions: high-intensity interval training; Other
Lead sponsor: University of New Mexico; Other
Eligibility: 18 Years to 45 Years
Enrollment: 18 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Albuquerque, New Mexico

Conditions: Acne Vulgaris
Interventions: adapalene 0.1% and benzoyl peroxide 2.5% topical gel, EPIDUO, Placebo (Vehicle Gel); Drug
Lead sponsor: Actavis Mid-Atlantic LLC; Industry
Eligibility: 12 Years to 40 Years
Enrollment: 885 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011
U.S. locations: 8
States / cities: Fremont, California • Miami, Florida • Miramar, Florida + 5 more

Conditions: Pharmacokinetics
Interventions: Raltegravir; Drug
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 18 Years to 49 Years · Female only
Enrollment: 7 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: Colitis Ulcerative
Interventions: Dupilumab, Placebo; Drug
Lead sponsor: Sanofi; Industry
Eligibility: 18 Years and older
Enrollment: 68 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2027
U.S. locations: 27
States / cities: Apple Valley, California • Beverly Hills, California • Oxnard, California + 24 more

Conditions: Respiratory Tract Infections
Interventions: Kefir, Placebo; Other
Lead sponsor: Georgetown University; Other
Eligibility: 1 Year to 5 Years
Enrollment: 125 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2008
U.S. locations: 1
States / cities: Washington D.C., District of Columbia

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Pharmacist-Assisted Titration of Rx to Implement Optimal Medical Therapy for Heart Failure

Non-Invasive Median Nerve Stimulation to Attenuate Atrial Tachyarrhythmias After Catheter Ablation for Atrial Fibrillation

The Young Adult and Pediatric Bipolar Study

Maladaptive Psychosocial Beliefs and Adolescents With Patellofemoral Pain

Clinical Investigation of the Effects of Semiconductor Embedded Therapeutic Garments on Cancer-related Cognitive Impairment in Breast and Gynecological Cancer Patients

Multi-site Feasibility and Acceptability of a Faith-based Mind-body Intervention for Black Adults

Multifamily Group to Reduce Marital Conflict and Disability in Veterans With mTBI

Pivotal Study on the NOVABLOC System for Patients Undergoing Primary Total Knee Arthroplasty

MoTHER Buddy Program

The Effects of Sensory Training On Pain Modulation, Cognition and Time to Fatigue in Healthy Adults

Evaluation of Efficacy of TOOKAD® (VTP) Versus Active Surveillance for Intermediate Risk Localized Prostate Cancer

Adaptive Recruitment Curve Analysis Using Bayesian Modeling

Exercise-induced Hypoalgesia After Comparative Forms of Exercise

Active Immunization of HIV-1 Infected, Pregnant Women With CD4 Lymphocyte Counts >= 400/mm3: A Phase I Study of Safety and Immunogenicity of VaxSyn Recombinant gp160 (NOTE: Some Patients Receive Placebo)

Initial Study of Insomnia/Nightmare Group Treatment for Posttraumatic Stress Disorder (PTSD)

NMDA Receptors in Motor Learning in Humans

Safety, Efficacy, Tolerability and Pharmacokinetics of NNC 0070-0002-0182 in Overweight or Obese Male and Female Volunteers

Comparative Efficacy and Safety of Ciprofloxacin 0.3% and Dexamethasone 0.1% in Acute Otitis Externa

iSTEP-N 101b: Pharmacokinetics and Safety Study of Low- and High-Dose Naltrexone Implants vs Monthly Vivitrol in Healthy Volunteers

High-intensity Interval Training for Obese Individuals

A Bioequivalence Study With Clinical Endpoints Comparing Adapalene and Benzoyl Peroxide Topical Gel 0.1%/2.5% (Actavis Mid-Atlantic LLC) To Epiduo™ (Adapalene and Benzoyl Peroxide) Gel 0.1%/2.5% (Galderma Laboratories, L.P.) in the Treatment of Mild to Severe Acne Vulgaris

Pharmacokinetic Study of Raltegravir in Healthy Premenopausal Women.

A Study to Investigate the Efficacy and Safety of Dupilumab Therapy Compared With Placebo in Participants Aged ≥18 Years With Moderately to Severely Active Ulcerative Colitis With an Eosinophilic Phenotype (LIBERTY-UC SUCCEED (Study in UC for Clinical Efficacy Evaluation of Dupilumab))

Measuring the Influence of Kefir on Children's Stools on Antibiotics (MILK)