Independent directory Public ClinicalTrials.gov records United States
Clear filters

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Nov 14, 2026, 10:50 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–7 of 7 matching trials from the live ClinicalTrials.gov search.
Conditions
Cigarette Smoking-Related Carcinoma
Interventions
Avoidance, Biospecimen Collection, Cigarette Smoking, Eye Movement Measurement, Healthcare Activity, Questionnaire Administration, Refrain from Smoking, Vaping, Standardized E-Cigarette Nicotine Administration
Behavioral · Procedure · Other + 1 more
Lead sponsor
Ohio State University Comprehensive Cancer Center
Other
Eligibility
21 Years to 50 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Columbus, Ohio
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Effects of Tobacco Flavoring and Liquid Composition on Vaping Topography

NCT05876091
Conditions
Tobacco-Related Carcinoma
Interventions
Vaping, Biospecimen Collection, Questionnaire Administration
Other · Procedure
Lead sponsor
Roswell Park Cancer Institute
Other
Eligibility
21 Years to 55 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Buffalo, New York
Recruiting Not applicable Interventional Accepts healthy volunteers

Vaping and Smoking Withdrawal Project

NCT05772845
Conditions
Acute Abstinence From Cigarettes vs E-cigarettes (ENDS)
Interventions
Acute (24-hour) abstinence, Ad libitum smoking/vaping
Behavioral
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
21 Years to 50 Years
Enrollment
370 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Buffalo, New York
Conditions
Acute Abstinence From Cigarettes vs E-cigarettes (ENDS)
Interventions
Acute (24-hour) abstinence, Ad libitum smoking/vaping
Behavioral
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
21 Years to 50 Years
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Buffalo, New York
Conditions
Tobacco Cessation, Electronic Nicotine Delivery Systems
Interventions
Vaping - Fruit flavored ENDS, Biospecimen Collection, Vaping - tobacco flavored ENDS
Other · Procedure
Lead sponsor
Roswell Park Cancer Institute
Other
Eligibility
21 Years and older
Enrollment
286 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Buffalo, New York
Conditions
Smoking Cessation
Interventions
Bupropion, Zonisamide, Placebo bupropion, Placebo zonisamide, E-cigarette
Drug · Other
Lead sponsor
Rose Research Center, LLC
Industry
Eligibility
21 Years to 65 Years
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
2
States / cities
Charlotte, North Carolina • Raleigh, North Carolina
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Zonisamide/Bupropion Effects on Switching to Electronic Cigarettes

NCT04388319
Conditions
Smoking Cessation
Interventions
Zonisamide, Bupropion, Halo G6 e-cigarette
Drug · Other
Lead sponsor
Rose Research Center, LLC
Industry
Eligibility
21 Years to 65 Years
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
2
States / cities
Charlotte, North Carolina • Raleigh, North Carolina