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Showing 1–24 of 32 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Air Colonoscopy Clear all
Terminated Phase 1Phase 2 Interventional Accepts healthy volunteers

Techniques to Enhance Patient Comfort in Sedation-risk Free Colonoscopy

NCT01076907
View directory record Official record
Conditions
Screening of Colonic Polyps
Interventions
Warm water, Control
Other
Lead sponsor
VA Greater Los Angeles Healthcare System
Federal
Eligibility
18 Years to 95 Years
Enrollment
85 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2011
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Dec 14, 2015 · Synced Sep 6, 2026, 1:36 AM EDT
Terminated Phase 3 Interventional Accepts healthy volunteers

Comparison of Adenoma Detection Rate Among Water, Carbon Dioxide and Air Methods of Minimal Sedation Colonoscopy

NCT01782014
View directory record Official record
Conditions
Screening Colonoscopy
Interventions
colonoscopy
Procedure
Lead sponsor
Loma Linda University
Other
Eligibility
18 Years to 80 Years
Enrollment
450 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Jan 31, 2016 · Synced Sep 6, 2026, 1:36 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Comparing Clinical Performance of Novice Trainee Endoscopists Using Conventional Air Insufflation Versus Warm Water Infusion Colonoscopy

NCT01482546
View directory record Official record
Conditions
Colonoscopy Education
Interventions
Not listed
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2016
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Jun 26, 2017 · Synced Sep 6, 2026, 1:36 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Comparative Efficacy of Water & Indigo Carmine vs. Water or Air Method on Adenoma Detection Rate (ADR) - a Randomized Controlled Trial (RCT)

NCT01607255
View directory record Official record
Conditions
Colorectal Neoplasms
Interventions
Indigo carmine, water (exchange) method, water (exchange) plus dye method, air method
Drug · Procedure
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
45 Years to 75 Years
Enrollment
480 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Jan 14, 2019 · Synced Sep 6, 2026, 1:36 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Comparision of Air Versus CO2 for Distention During Sigmoidoscopy

NCT00771290
View directory record Official record
Conditions
Colorectal Surgery
Interventions
Air insufflation with standard endoscopy unit, CO2 insufflation for colonoscopy (special CO2 insufflation unit)
Procedure
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
54 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 30, 2024 · Synced Sep 6, 2026, 1:36 AM EDT
Completed Not applicable Interventional

Carbon Dioxide Insufflation Versus Conventional Air Insufflation

NCT02790359
View directory record Official record
Conditions
Abdominal Pain
Interventions
Air, Carbon dioxide
Other
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
8 Years to 21 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Dec 12, 2019 · Synced Sep 6, 2026, 1:36 AM EDT
Completed Not applicable Interventional Results available

Clinical Evaluation of Water Immersion Colonoscopy Insertion Technique

NCT00671177
View directory record Official record
Conditions
Colonoscopy, Digestive System, Endoscopy, Gastrointestinal Disease
Interventions
water immersion colonoscopy, standard air colonoscopy
Procedure
Lead sponsor
VA Palo Alto Health Care System
Federal
Eligibility
18 Years and older · Male only
Enrollment
229 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Apr 30, 2017 · Synced Sep 6, 2026, 1:36 AM EDT
Completed Not applicable Interventional

Water-aided Colonoscopy vs Air Insufflation Colonoscopy in Colorectal Cancer Screening

NCT02041507
View directory record Official record
Conditions
Colorectal Cancer, Colorectal Adenomas, Colorectal Polyps, Pain
Interventions
Air insufflation method., Water Immersion method., Water Exchange method.
Other
Lead sponsor
Presidio Ospedaliero Santa Barbara
Other
Eligibility
50 Years to 70 Years
Enrollment
1,224 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 12, 2016 · Synced Sep 6, 2026, 1:36 AM EDT
Completed Not applicable Interventional

Comparison of Methods to Distend the Colon During Insertion: CO2, Air Insufflation, Water-aided Colonoscopy

NCT01954862
View directory record Official record
Conditions
Pain, Colorectal Adenomas, Colorectal Cancer
Interventions
Air Insufflation method., CO2 insufflation, Water Immersion/CO2, Water Exchange/CO2, Water Immersion/AI, Water Exchange/AI
Other
Lead sponsor
Presidio Ospedaliero Santa Barbara
Other
Eligibility
18 Years to 85 Years
Enrollment
624 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jul 30, 2014 · Synced Sep 6, 2026, 1:36 AM EDT
Withdrawn Not applicable Interventional

Comparison of High-flow Oxygen With or Without Nasal Positive Airway Pressure (PAP) During Propofol Sedation for Colonoscopy in an Ambulatory Surgical Center

NCT05754255
View directory record Official record
Conditions
Colonoscopy, Positive-Pressure Respiration
Interventions
Nasal Cannula, Nasal Positive Airway Pressure System
Device
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Feb 23, 2026 · Synced Sep 6, 2026, 1:36 AM EDT
Completed Not applicable Interventional

Comparing the Adenoma Detection Rate With Air Insufflation, Water Immersion and Water Exchange

NCT01894191
View directory record Official record
Conditions
Adenoma
Interventions
Air insufflation, water immersion, Water exchange
Procedure
Lead sponsor
Dalin Tzu Chi General Hospital
Other
Eligibility
20 Years to 80 Years
Enrollment
651 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
North Hills, California
Source: ClinicalTrials.gov public record
Updated Jun 27, 2016 · Synced Sep 6, 2026, 1:36 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Prospective RCT Of Water Exchange (WE) vs. WE Plus Cap-Assisted Colonoscopy

NCT03160859
View directory record Official record
Conditions
Unsedated Colonoscopy, Water Exchange Colonoscopy, Cap, Colonoscopy Pain
Interventions
Control, Study method
Other · Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
50 Years to 80 Years
Enrollment
280 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
3
States / cities
Palo Alto, California • Sacramento, California • Sepulveda, California
Source: ClinicalTrials.gov public record
Updated Dec 11, 2023 · Synced Sep 6, 2026, 1:36 AM EDT
Completed Not applicable Interventional

Comparing the ADR With Air Insufflation, Water Immersion and Water Exchange During Two-endoscopist Colonoscopy

NCT02737514
View directory record Official record
Conditions
Adenoma
Interventions
Air insufflation, water immersion, water exchange
Procedure
Lead sponsor
Dalin Tzu Chi General Hospital
Other
Eligibility
20 Years to 80 Years
Enrollment
371 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
North Hills, California
Source: ClinicalTrials.gov public record
Updated May 28, 2020 · Synced Sep 6, 2026, 1:36 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Comparison of on Demand Sedation With Study Method Versus on Demand Sedation With Conventional Method for Performing Colonoscopy for Colorectal Cancer Screening and Surveillance

NCT00920751
View directory record Official record
Conditions
Colorectal Cancer Screening
Interventions
Water infusion, Air insufflation
Procedure
Lead sponsor
East Bay Institute for Research and Education
Other
Eligibility
50 Years to 80 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2009
U.S. locations
1
States / cities
Mather, California
Source: ClinicalTrials.gov public record
Updated Jun 14, 2009 · Synced Sep 6, 2026, 1:36 AM EDT
Completed Not applicable Interventional

A Comparison of Air Insufflation, Water Immersion and Water Exchange Colonoscopy in Diagnostic Patients

NCT01781650
View directory record Official record
Conditions
Pain, Colorectal Adenomas, Colorectal Cancer
Interventions
Air Insufflation method., Water Immersion method., Water Exchange method.
Other
Lead sponsor
Presidio Ospedaliero Santa Barbara
Other
Eligibility
18 Years to 85 Years
Enrollment
288 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jan 14, 2014 · Synced Sep 6, 2026, 1:36 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effectiveness and Safety of the Colonoscopy With "Visualization" Balloon

NCT02117232
View directory record Official record
Conditions
Colonic Adenomatous Polyps
Interventions
Visualization balloon, Traditional CO2 insufflation colonoscopy
Device
Lead sponsor
Mercy Medical Center
Other
Eligibility
17 Years to 90 Years
Enrollment
216 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 20, 2018 · Synced Sep 6, 2026, 1:36 AM EDT
Completed Not applicable Interventional

Combined Chromoendoscopy and Water Method for Screening Colonoscopy

NCT01383265
View directory record Official record
Conditions
Colon Polyp
Interventions
Water method and chromoendoscopy, Water method
Procedure
Lead sponsor
VA Northern California Health Care System
Federal
Eligibility
50 Years to 75 Years
Enrollment
1,177 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Mather, California
Source: ClinicalTrials.gov public record
Updated Jun 16, 2013 · Synced Sep 6, 2026, 1:36 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Does the Cap Increase the Finding of Polyps When Water Exchange Colonoscopy is Used

NCT03566615
View directory record Official record
Conditions
Colonoscopy, Polyp of Colon
Interventions
CAP-straight, CAP-daisy, water
Device · Other
Lead sponsor
VA Greater Los Angeles Healthcare System
Federal
Eligibility
50 Years to 75 Years
Enrollment
1,630 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
2
States / cities
Mather, California • Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Oct 5, 2022 · Synced Sep 6, 2026, 1:36 AM EDT
Completed Not applicable Interventional

A Comparison of Air Insufflation, Water Immersion and Water Exchange Colonoscopy in CRC Screening

NCT01780818
View directory record Official record
Conditions
Pain, Colorectal Adenomas, Colorectal Cancer
Interventions
Air Insufflation method., Water Immersion method., Water Exchange method.
Other
Lead sponsor
Presidio Ospedaliero Santa Barbara
Other
Eligibility
50 Years to 70 Years
Enrollment
288 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jan 14, 2014 · Synced Sep 6, 2026, 1:36 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Investigation of Cecal Intubation Rates and Pain Levels Between Water Exchange and Air Insufflation Flexible Sigmoidoscopy

NCT03209349
View directory record Official record
Conditions
Colorectal Cancer
Interventions
Water Exchange Sigmoidoscopy, Air Insufflation Sigmoidoscopy
Procedure
Lead sponsor
Kelowna Gastroenterology Associates
Other
Eligibility
50 Years to 74 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
1
States / cities
North Hills, California
Source: ClinicalTrials.gov public record
Updated Nov 6, 2022 · Synced Sep 6, 2026, 1:36 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Colon Capsule Endoscopy (CCE) Versus Computed Tomographic Colonography (CTC) in the Identification of Colonic Polyps in a Screening Population.

NCT02754661
View directory record Official record
Conditions
Colorectal Cancer Screening
Interventions
COLON Capsule endoscopy, Computed Tomographic Colonography
Device
Lead sponsor
Medtronic - MITG
Industry
Eligibility
50 Years to 75 Years
Enrollment
320 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
13
States / cities
Mobile, Alabama • Jacksonville, Florida • Chicago, Illinois + 8 more
Source: ClinicalTrials.gov public record
Updated Sep 30, 2019 · Synced Sep 6, 2026, 1:36 AM EDT
Terminated Not applicable Interventional

Comparison of Barium Enema, Computed Tomographic Colonography, and Colonoscopy in Detecting Colon Cancer

NCT00016029
View directory record Official record
Conditions
Colorectal Cancer
Interventions
screening questionnaire administration, barium enema injection, computed tomography, computed tomography colonography, diagnostic colonoscopy, screening colonoscopy
Other · Procedure
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
775 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2005
U.S. locations
14
States / cities
La Jolla, California • San Francisco, California • Vero Beach, Florida + 8 more
Source: ClinicalTrials.gov public record
Updated Mar 21, 2013 · Synced Sep 6, 2026, 1:36 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Genetic Determinants of Barrett's Esophagus and Esophageal Adenocarcinoma

NCT00288119
View directory record Official record
Conditions
Barrett's Esophagus, Esophageal Neoplasm
Interventions
Balloon Capsule Device, Endoscopy
Device · Procedure
Lead sponsor
Case Western Reserve University
Other
Eligibility
18 Years and older
Enrollment
2,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2028
U.S. locations
10
States / cities
Baltimore, Maryland • Rochester, Minnesota • St Louis, Missouri + 5 more
Source: ClinicalTrials.gov public record
Updated Aug 9, 2026 · Synced Sep 6, 2026, 1:36 AM EDT
Completed Not applicable Interventional

Underwater Resection of Non-pedunculated Colorectal Lesions

NCT02889679
View directory record Official record
Conditions
Colorectal Neoplasms
Interventions
Underwater resection, Conventional (gas distended colon) resection, Standard polypectomy
Procedure
Lead sponsor
VA Northern California Health Care System
Federal
Eligibility
18 Years and older
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Mather, California
Source: ClinicalTrials.gov public record
Updated Dec 19, 2018 · Synced Sep 6, 2026, 1:36 AM EDT