- Conditions
- Plastic Bronchitis, Protein-Losing Enteropathies, Healthy
- Interventions
- Treatment-inhaled tPA
- Drug
- Lead sponsor
- University of Michigan
- Other
- Eligibility
- 5 Years to 24 Years
- Enrollment
- 40 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018 – 2023
- U.S. locations
- 6
- States / cities
- Palo Alto, California • Chicago, Illinois • Ann Arbor, Michigan + 3 more
Search Results
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Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results are retrieved from ClinicalTrials.gov and synchronized into the directory. Search pages remain noindex by default.
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Showing 1–24
of 123
matching trials from the live ClinicalTrials.gov search.
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- Conditions
- Acute Stroke
- Interventions
- Acute Endovascular Stroke Treatment
- Other
- Lead sponsor
- Icahn School of Medicine at Mount Sinai
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 191 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2019
- U.S. locations
- 4
- States / cities
- New York, New York
- Conditions
- Hypertension, Diabetes Type 2
- Interventions
- Sitagliptin (DPP4 inhibitor), Substance P,, bradykinin, enalaprilat (ACE inhibitor), Glucagon-like peptide 1, brain natriuretic peptide
- Drug
- Lead sponsor
- Vanderbilt University
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 44 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2011 – 2014
- U.S. locations
- 1
- States / cities
- Nashville, Tennessee
- Conditions
- Pleural Effusion Associated With Pulmonary Infection, Pleural Effusion Disorder, Pleural Effusions
- Interventions
- Pleural Saline Irrigation
- Combination Product
- Lead sponsor
- Beth Israel Deaconess Medical Center
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 96 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2027
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Tissue Plasminogen Activator
- Interventions
- early tPA and DNase
- Combination Product
- Lead sponsor
- Prisma Health-Midlands
- Other
- Eligibility
- 18 Years to 100 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2021
- U.S. locations
- 1
- States / cities
- Columbia, South Carolina
- Conditions
- Stroke
- Interventions
- tenecteplase, tissue plasminogen activator, tPA
- Drug
- Lead sponsor
- University of Virginia
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 112 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2005 – 2009
- U.S. locations
- 9
- States / cities
- San Diego, California • Englewood, Colorado • Baltimore, Maryland + 5 more
- Conditions
- Ischemic Stroke, Acute Disease
- Interventions
- tenecteplase
- Drug
- Lead sponsor
- ProMedica Health System
- Other
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 132 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2028
- U.S. locations
- 1
- States / cities
- Toledo, Ohio
- Conditions
- Ischemic Stroke
- Interventions
- IV tpa (Alteplase) vs IA tpa (Alteplase)
- Drug
- Lead sponsor
- University of North Carolina, Chapel Hill
- Other
- Eligibility
- 19 Years and older
- Enrollment
- 7 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2004 – 2008
- U.S. locations
- 1
- States / cities
- Chapel Hill, North Carolina
- Conditions
- Pulmonary Embolism, Pulmonary Hypertension, Thromboembolism, Right Ventricular Dysfunction
- Interventions
- Alteplase, EKOS
- Drug · Device
- Lead sponsor
- Northwell Health
- Other
- Eligibility
- 18 Years to 89 Years
- Enrollment
- 31 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2025
- U.S. locations
- 2
- States / cities
- Bay Shore, New York • Queens, New York
- Conditions
- Stroke
- Interventions
- 2-MHz transcranial Doppler ultrasound, 2-MHz transcranial Doppler ultrasound insonation
- Device
- Lead sponsor
- The University of Texas Health Science Center, Houston
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 35 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2008 – 2013
- U.S. locations
- 2
- States / cities
- Birmingham, Alabama • Houston, Texas
- Conditions
- Ischemic Stroke
- Interventions
- Transcranial Laser Therapy
- Device
- Lead sponsor
- University of California, San Diego
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 12 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2013
- U.S. locations
- 3
- States / cities
- Englewood, Colorado • Columbia, South Carolina • Spokane, Washington
- Conditions
- Loculated or Non-draining Malignant Pleural Effusions
- Interventions
- Combination TISSUE PLASMINOGEN ACTIVATOR (TPA) AND DORNASE ALFA (DNASE)
- Drug
- Lead sponsor
- Eastern Regional Medical Center
- Other
- Eligibility
- 18 Years to 99 Years
- Enrollment
- 10 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2021
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- Ischemic Stroke
- Interventions
- Alteplase (tPA)
- Drug
- Lead sponsor
- University of California, San Diego
- Other
- Eligibility
- 22 Years and older
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- Started 2011
- U.S. locations
- 1
- States / cities
- San Diego, California
- Conditions
- Intracerebral Hemorrhage
- Interventions
- MIS+Cathflo Activase (drug), Intraoperative stereotactic CT-Guided Endoscopic Surgery
- Drug · Procedure
- Lead sponsor
- Daniel Hanley
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 141 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2005 – 2013
- U.S. locations
- 26
- States / cities
- Birmingham, Alabama • Phoenix, Arizona • Los Angeles, California + 19 more
- Conditions
- Ischemic Stroke
- Interventions
- Low Dose Argatroban, High Dose Argatroban, rt-PA (alteplase)
- Drug
- Lead sponsor
- Andrew D. Barreto, MD
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 90 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2015
- U.S. locations
- 1
- States / cities
- Houston, Texas
- Conditions
- Pleural Infection, Empyema, Pleural Diseases, Parapneumonic Effusion
- Interventions
- tissue plasminogen activator (tPA) and human recombinant deoxyribonuclease (DNase), Medical Thoracoscopy
- Drug · Procedure
- Lead sponsor
- Tulane University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 32 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2019
- U.S. locations
- 1
- States / cities
- New Orleans, Louisiana
- Conditions
- Acute Stroke
- Interventions
- IV rt-PA
- Drug
- Lead sponsor
- Lee Schwamm
- Other
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 88 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2016
- U.S. locations
- 14
- States / cities
- Tucson, Arizona • Los Angeles, California • Chicago, Illinois + 8 more
- Conditions
- Stroke, Brain Ischemia
- Interventions
- ThermoSuit Cooling Induction, Magnesium Sulfate, tPA, Propofol, Etomidate, Neurothrombectomy
- Device · Drug · Procedure
- Lead sponsor
- Life Recovery Systems
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 14 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2023
- U.S. locations
- 4
- States / cities
- New Orleans, Louisiana • Danville, Pennsylvania • Wilkes-Barre, Pennsylvania + 1 more
- Conditions
- Pleural Effusion
- Interventions
- normal saline, TNK (Tenecteplase)
- Drug
- Lead sponsor
- Kaiser Permanente
- Other
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2011
- U.S. locations
- 1
- States / cities
- Honolulu, Hawaii
- Conditions
- Acute Respiratory Distress Syndrome
- Interventions
- Tenecteplase
- Drug
- Lead sponsor
- Wake Forest University Health Sciences
- Other
- Eligibility
- 18 Years to 75 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2008
- U.S. locations
- 1
- States / cities
- Macon, Georgia
- Conditions
- Stroke
- Interventions
- Tissue plasminogen activator (Activase®)
- Drug
- Lead sponsor
- Seattle Children's Hospital
- Other
- Eligibility
- 2 Years to 17 Years
- Enrollment
- 1 participant
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2013
- U.S. locations
- 13
- States / cities
- Palo Alto, California • Aurora, Colorado • Boston, Massachusetts + 9 more
- Conditions
- Acute Peripheral Arterial Occlusion
- Interventions
- Plasmin, Plasminogen Activator, Placebo
- Biological · Other
- Lead sponsor
- Grifols Therapeutics LLC
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 174 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2016
- U.S. locations
- 2
- States / cities
- Buffalo, New York • Cleveland, Ohio
- Conditions
- Acute Submassive Pulmonary Embolism
- Interventions
- The Bashir™ Endovascular Catheter (BEC
- Device
- Lead sponsor
- Temple University
- Other
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2025
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- Pleural Diseases
- Interventions
- Chest thoracoscopy, Chest fibrinolytic therapy, tPA, DNase
- Procedure · Drug
- Lead sponsor
- University of Florida
- Other
- Eligibility
- 18 Years to 90 Years
- Enrollment
- 5 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2020
- U.S. locations
- 1
- States / cities
- Gainesville, Florida