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ClinicalTrials.gov public records Last synced Nov 6, 2026, 12:42 PM EST

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Showing 1–24 of 52 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Amblyopia Therapy Clear all

Conditions: Amblyopia
Interventions: iPad®, Patching 2 hours per day, 7 days per week; Device · Other
Lead sponsor: Jaeb Center for Health Research; Other
Eligibility: 5 Years to 16 Years
Enrollment: 485 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 2
States / cities: Rochester, Minnesota • Seattle, Washington

Conditions: Amblyopia
Interventions: Luminopia, Eye Patch; Device · Other
Lead sponsor: Jaeb Center for Health Research; Other
Eligibility: 4 Years to 7 Years
Enrollment: 238 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2028
U.S. locations: 72
States / cities: Birmingham, Alabama • Glendale, Arizona • Scottsdale, Arizona + 58 more

Conditions: Toxic Effect of Organophosphate and Carbamate Insecticides
Interventions: Atropine Sulfate Ophthalmic Solution, Atropine Sulphate Injection; Drug
Lead sponsor: Biomedical Advanced Research and Development Authority; Federal
Eligibility: 18 Years to 55 Years
Enrollment: 15 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020
U.S. locations: 1
States / cities: High Point, North Carolina

Conditions: Amblyopia
Interventions: OkuStim®, Sham-OkuStim®; Device
Lead sponsor: Wills Eye; Other
Eligibility: 18 Years and older
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2020
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Amblyopia
Interventions: Amblyopia Therapy, 1 mg Psilocybin, 5 mg Psilocybin, 10 mg Psilocybin, 15 mg Psilocybin, 20 mg Psilocybin, 25 mg Psilocybin; Behavioral · Drug
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Amblyopia
Interventions: Levodopa/Carbidopa, Placebo, Patching; Drug · Other
Lead sponsor: Jaeb Center for Health Research; Other
Eligibility: 7 Years to 12 Years
Enrollment: 139 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2014
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Amblyopia, Amblyopia Unilateral, Amblyopia, Anisometropic, Amblyopia Strabismic
Interventions: Valproate, Placebo, Patch; Drug · Behavioral
Lead sponsor: Boston Children's Hospital; Other
Eligibility: 8 Years to 17 Years
Enrollment: 28 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Amblyopia
Interventions: Atropine, Plano lens; Drug · Device
Lead sponsor: Jaeb Center for Health Research; Other
Eligibility: 3 Years to 7 Years
Enrollment: 73 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2013
U.S. locations: 2
States / cities: Fullerton, California • Durham, North Carolina

Conditions: Amblyopia
Interventions: Binocular deprivation 10 days, Vision training; Behavioral
Lead sponsor: State University of New York College of Optometry; Other
Eligibility: 18 Years and older
Enrollment: 8 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2019
U.S. locations: 1
States / cities: New York, New York

Conditions: Refractory Amblyopia
Interventions: Echothiophate Iodide 0.125% Ophthalmic Solution; Drug
Lead sponsor: University of Oklahoma; Other
Eligibility: 3 Years to 17 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026
U.S. locations: 1
States / cities: Oklahoma City, Oklahoma

Conditions: Amblyopia
Interventions: Binocular games for treatment of amblyopia; Other
Lead sponsor: Retina Foundation of the Southwest; Other
Eligibility: 4 Years to 10 Years
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2026
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Amblyopia
Interventions: Perceptual learning, Video Games, Occlusion therapy; Behavioral
Lead sponsor: University of California, Berkeley; Other
Eligibility: 5 Years to 75 Years
Enrollment: 50 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2022
U.S. locations: 1
States / cities: Berkeley, California

Conditions: Amblyopia
Interventions: Vivid Vision, Luminopia, Optical Correction; Device
Lead sponsor: Jaeb Center for Health Research; Other
Eligibility: 8 Years to 12 Years
Enrollment: 252 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2028
U.S. locations: 58
States / cities: Birmingham, Alabama • Glendale, Arizona • Scottsdale, Arizona + 46 more

Conditions: Amblyopia
Interventions: Bangerter filters, Patching, Near activities; Device · Procedure
Lead sponsor: Jaeb Center for Health Research; Other
Eligibility: 3 Years to 9 Years
Enrollment: 186 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2009
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Amblyopia
Interventions: Patching, Near activities, Active vision therapy, Control vision therapy; Device · Procedure
Lead sponsor: Jaeb Center for Health Research; Other
Eligibility: 7 Years to 12 Years
Enrollment: 19 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2009
U.S. locations: 7
States / cities: Birmingham, Alabama • Miami, Florida • Bloomington, Indiana + 4 more

Conditions: Bilateral Refractive Amblyopia
Interventions: Spectacles; Device
Lead sponsor: Jaeb Center for Health Research; Other
Eligibility: 3 Years to 10 Years
Enrollment: 113 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2006
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Amblyopia
Interventions: CureSight, Patching; Device
Lead sponsor: NovaSight; Industry
Eligibility: 4 Years to 8 Years
Enrollment: 23 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Virginia Beach, Virginia

Conditions: Amblyopia
Interventions: IO-therapy Glasses; Device
Lead sponsor: Salus University; Other
Eligibility: 3 Years to 8 Years
Enrollment: 32 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2021
U.S. locations: 1
States / cities: Elkins Park, Pennsylvania

Conditions: Amblyopia
Interventions: Atropine, Plano Lens; Drug · Device
Lead sponsor: Jaeb Center for Health Research; Other
Eligibility: 3 Years to 6 Years
Enrollment: 240 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2008
U.S. locations: 2
States / cities: Fullerton, California • Dallas, Texas

Conditions: Amblyopia
Interventions: patching, Dichoptic videos; Other
Lead sponsor: Retina Foundation of the Southwest; Other
Eligibility: 3 Years to 7 Years
Enrollment: 65 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Atropine Bioequivalence
Interventions: Atropine Sulfate Ophthalmic Solution USP, 1%, Atropine Sulfate Injection, USP 8 mg/20 mL (0.4 mg/mL); Drug
Lead sponsor: Biomedical Advanced Research and Development Authority; Federal
Eligibility: 18 Years to 65 Years
Enrollment: 46 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024
U.S. locations: 1
States / cities: Lenexa, Kansas

Conditions: Amblyopia, Strabismus
Interventions: Binocular Treatment, Sham Binocular Treatment; Procedure
Lead sponsor: Massachusetts Eye and Ear Infirmary; Other
Eligibility: 18 Years to 60 Years
Enrollment: 22 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2016
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Amblyopia
Interventions: Prescription glasses for bilateral amblyopia, Prescription glasses for unilateral amblyopia; Other
Lead sponsor: Salus University; Other
Eligibility: 3 Years to 10 Years
Enrollment: 1 participant
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Elkins Park, Pennsylvania

Conditions: Amblyopia
Interventions: Atropine, Eye Patch; Drug · Device
Lead sponsor: Jaeb Center for Health Research; Other
Eligibility: Up to 6 Years
Enrollment: 419 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 1999 – 2013
U.S. locations: 1
States / cities: Baltimore, Maryland

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Study of Binocular Computer Activities for Treatment of Amblyopia

Dichoptic Treatment for Amblyopia in Children 4 to 7 Years of Age

Sublingual vs IV Atropine Bioavailability Study

Transcorneal Electrical Stimulation (TES) for the Treatment of Amblyopia

Psilocybin for Amblyopia - Targeting Critical Periods in Humans

Levodopa for the Treatment of Residual Amblyopia

Valproate for the Treatment of Residual Amblyopia

Augmenting Atropine Treatment for Amblyopia in Children 3 to < 8 Years Old

Light-deprivation Utilized to Mitigate Amblyopia

Evaluation of Echothiophate in Pediatric Patients With Refractory Amblyopia

Binocular Amblyopia Treatment

An Active Approach to Treat Amblyopia: Perceptual Learning and Video Games

Dichoptic Treatment for Amblyopia in Children 8 to 12 Years of Age

Full-time Bangerter Filters Versus Part-time Daily Patching for Moderate Amblyopia in Children

Trial Comparing Patching With Active Vision Therapy to Patching With Control Vision Therapy as Treatment for Amblyopia

Bilateral Refractive Amblyopia Treatment Study

CURESIGHT BINOCULAR AMBLYOPIA TREATMENT STUDY

Regimens of Intermittent Occlusion Therapy for Amblyopia in Children

Trial Comparing Atropine to Atropine Plus a Plano Lens for the Sound Eye for Amblyopia in Children 3 to <7 Years Old

Dichoptic Video Treatment for Amblyopia

Sublingual Atropine Bioequivalence by Route of Administration (SABER)

Binocular Treatment of Amblyopia Before and After Strabismus Surgery

Bilateral and Unilateral Amblyopia Treatment Study

Occlusion Versus Pharmacologic Therapy for Moderate Amblyopia