- Conditions
- Staphylococcus Aureus Colonization, Surgical Site Infections, Healthcare Associated Infections
- Interventions
- Screening and decolonization for SA carriers with the 3 drug bundle, No screening for SA, no screening, Nasal povidone-iodine on surgery day plus 2 CHG pre-op showers without screening., Nasal alcohol gel on surgery day plus 2 CHG pre-op showers without screening
- Other
- Lead sponsor
- University of Minnesota
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 250 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2026
- U.S. locations
- 1
- States / cities
- Minneapolis, Minnesota
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Showing 1–9
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- Conditions
- Bacterial Colonization
- Interventions
- Mupirocin, Chlorhexidine baths
- Drug
- Lead sponsor
- Duke University
- Other
- Eligibility
- 18 Years and older · Female only
- Enrollment
- 1 participant
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024
- U.S. locations
- 1
- States / cities
- Durham, North Carolina
- Conditions
- Hospitalization, Infection
- Interventions
- Chlorhexidine gluconate (CHG), Iodophor (10% povidone-iodine)
- Drug
- Lead sponsor
- University of California, Irvine
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 13,952 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2023
- U.S. locations
- 28
- States / cities
- Anaheim, California • Bellflower, California • Capistrano Beach, California + 9 more
- Conditions
- Skin and Subcutaneous Tissue Bacterial Infections, Staphylococcus Aureus, MRSA - Methicillin Resistant Staphylococcus Aureus Infection
- Interventions
- Chlorhexidine, Mupirocin, Household cleaning
- Drug · Behavioral
- Lead sponsor
- Washington University School of Medicine
- Other
- Eligibility
- Up to 18 Years
- Enrollment
- 835 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2024
- U.S. locations
- 2
- States / cities
- St Louis, Missouri
- Conditions
- Staphylococcus Aureus
- Interventions
- Arm 1. Routine Care (Mupirocin/CHG), Arm 2. Iodophor/CHG Decolonization
- Drug
- Lead sponsor
- Harvard Pilgrim Health Care
- Other
- Eligibility
- Not listed
- Enrollment
- 353,323 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2023
- U.S. locations
- 137
- States / cities
- Riverside, California • San Jose, California • Thousand Oaks, California + 103 more
- Conditions
- Methicillin-Resistant Staphylococcus Aureus
- Interventions
- Retapamulin, Placebo
- Drug
- Lead sponsor
- University of California, Irvine
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 53 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2017
- U.S. locations
- 1
- States / cities
- Irvine, California
- Conditions
- Methicillin-resistant Staphylococcus Aureus
- Interventions
- Chlorhexidine bath and nasal mupirocin
- Drug
- Lead sponsor
- Harvard Pilgrim Health Care
- Other
- Eligibility
- 13 Years and older
- Enrollment
- 74,256 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2011
- U.S. locations
- 42
- States / cities
- Anchorage, Alaska • Thousand Oaks, California • Aurora, Colorado + 32 more
- Conditions
- Healthcare Associated Infections, Methicillin Resistant Staphylococcus Aureus, Multi Drug Resistant Organisms
- Interventions
- Arm 2: Decolonization
- Drug
- Lead sponsor
- University of California, Irvine
- Other
- Eligibility
- 12 Years and older
- Enrollment
- 53 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2019
- U.S. locations
- 52
- States / cities
- West Hills, California • Thornton, Colorado • Bradenton, Florida + 42 more
- Conditions
- Surgical Site Infection
- Interventions
- 4% Chlorhexidine Gluconate, 2% Mupirocin, Soap Without Antiseptic Properties (Placebo), Placebo Nasal Ointment
- Drug
- Lead sponsor
- University of California, Irvine
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 2,700 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2027
- U.S. locations
- 4
- States / cities
- Newport Beach, California • Orange, California • Sacramento, California + 1 more