Independent directory Public ClinicalTrials.gov records United States
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ClinicalTrials.gov public records Last synced Sep 18, 2026, 1:32 PM EDT

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Showing 1–23 of 23 matching trials from the live ClinicalTrials.gov search.
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Conditions
Atrial Fibrillation Chronic
Interventions
OPTIMA-guided catheter ablation, Standard PVI
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
67 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
1
States / cities
Baltimore, Maryland
Conditions
Atrial Fibrillation
Interventions
Unique measurement (AutoSTRAIN) by a commercial software program (TOMTEC-ARENA)
Device
Lead sponsor
Crystal Blake-Parlin
Other
Eligibility
Not listed
Enrollment
209 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Rockport, Maine
Conditions
Atrial Fibrillation, Atrial Flutter
Interventions
Zio®XT Monitor
Other
Lead sponsor
Bristol-Myers Squibb
Industry
Eligibility
70 Years and older
Enrollment
11,931 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
176
States / cities
Birmingham, Alabama • Guntersville, Alabama • Montgomery, Alabama + 141 more
Conditions
Ischemic Stroke, Cryptogenic, Ischemic Stroke, Embolic, Hemorrhagic Stroke, Embolic Stroke of Undetermined Source, Recurrent Ischemic Stroke
Interventions
Not listed
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
900 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Conditions
Atrial Fibrillation, Stroke
Interventions
Early Patient-Level and Provider-Level Educational Intervention, Delayed Provider-Level Educational Intervention
Behavioral
Lead sponsor
Harvard Pilgrim Health Care
Other
Eligibility
30 Years and older
Enrollment
64,666 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
4
States / cities
Louisville, Kentucky • Quincy, Massachusetts • Waltham, Massachusetts + 1 more
Conditions
Atrial Fibrillation, Stroke
Interventions
Chart Review
Other
Lead sponsor
MaineHealth
Other
Eligibility
Not listed
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Rockport, Maine
Conditions
Thromboembolism
Interventions
IWPC adapted genotype-guided dosing algorithm for warfarin, Modified IWPC genetic-guided warfarin dosing algorithm, Standard of care treatment
Genetic · Other
Lead sponsor
Intermountain Health Care, Inc.
Other
Eligibility
18 Years and older
Enrollment
2,415 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Salt Lake City, Utah
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Identification of Genetic, Biochemical and Hormonal Factors Contributing to Atrial Fibrillation

NCT00599118
Conditions
Atrial Fibrillation
Interventions
Not listed
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
1,300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2035
U.S. locations
1
States / cities
Cleveland, Ohio
Completed Not applicable Interventional Results available

Arrhythmia Detection In Obstructive Sleep Apnea (ADIOS)

NCT02743520
Conditions
Atrial Fibrillation, Arrhythmia, Stroke, Cardiovascular
Interventions
The Lifestar Act III
Device
Lead sponsor
University of Miami
Other
Eligibility
40 Years to 85 Years
Enrollment
86 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Miami, Florida
Active, not recruiting Not applicable Interventional

Pulsed-Field Ablation With/Without Electrogram Mapping

NCT07541989
Conditions
Non-paroxysmal Atrial Fibrillation
Interventions
PFA-based PVI+PWI plus adjunctive ablation guided by Electrogram Mapping of Key Substrates, PFA-based PVI+PWI alone
Procedure
Lead sponsor
Xu Liu
Other
Eligibility
18 Years to 80 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
The Bronx, New York
Conditions
Atrial Fibrillation
Interventions
None/Observational Studies
Other
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
15 Years and older
Enrollment
155 participants
Timeline
2022 – 2026
U.S. locations
1
States / cities
Nashville, Tennessee
Conditions
Atrial Fibrillation, Frailty, Anticoagulant-induced Bleeding, Stroke
Interventions
Warfarin, Dabigatran, Rivaroxaban, Apixaban, Edoxaban
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
65 Years and older
Enrollment
1,000,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Atrial Fibrillation, Persistent, Atrial Fibrillation, Arrhythmias, Cardiac, Heart Diseases
Interventions
Electrographic Flow™ (EGF) mapping and ablation
Device
Lead sponsor
Ablacon, Inc.
Industry
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
3
States / cities
Athens, Georgia • Atlanta, Georgia • New York, New York
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Detection and Classification of Cardiac Rhythm and Atrial Fibrillation Using a Finger-worn Ring

NCT06892938
Conditions
Atrial Fibrillation (AF), Arrhythmias Cardiac, Tachycardia, Palpitations, Bradycardia
Interventions
Atrial Fibrillation Identification
Diagnostic Test
Lead sponsor
Everbeat
Industry
Eligibility
18 Years and older
Enrollment
232 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
3
States / cities
La Jolla, California • Baton Rouge, Louisiana • Pittsburgh, Pennsylvania
Completed No phase listed Observational

Markers of Atrial Fibrillation

NCT02734758
Conditions
Stroke, Atrial Fibrillation
Interventions
Not listed
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
131 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2020
U.S. locations
1
States / cities
Sacramento, California
Conditions
Atrial Fibrillation
Interventions
PVS-PVI targeted ablation, Wide area circumferential ablation (WACA)
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Houston, Texas
Conditions
Atrial Fibrillation, Mitral Valve Insufficiency, Mitral Valve Stenosis
Interventions
MVS, Ablation
Procedure · Device
Lead sponsor
Annetine Gelijns
Other
Eligibility
18 Years and older
Enrollment
260 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
18
States / cities
New Haven, Connecticut • Newark, Delaware • Atlanta, Georgia + 14 more
Conditions
Atrial Fibrillation - Symptomatic
Interventions
Radiofrequency ablation
Procedure
Lead sponsor
Ohad Ziv
Other
Eligibility
18 Years to 85 Years
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2027
U.S. locations
1
States / cities
Cleveland, Ohio
Conditions
Coronary Artery Disease, Atrial Fibrillation (AF)
Interventions
Hybrid procedure, Endocardial ablations, left atrial appendage occlusion
Procedure
Lead sponsor
Cardiovascular Innovation and Research Institute
Other
Eligibility
18 Years and older
Enrollment
1,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2030
U.S. locations
1
States / cities
Glenwood Springs, Colorado
Conditions
Atrial Fibrillation (AF), Persistant Atrial Fibrillation
Interventions
FARAPOINT Pulsed Field Ablation System, OptiMap System (non-ablative), FARAPULSE Pulsed Field Ablation (PFA) System and Opal HDx Mapping System
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
699 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
11
States / cities
Jonesboro, Arkansas • Santa Monica, California • Athens, Georgia + 8 more
Conditions
Atrial Fibrillation
Interventions
Radiofrequency ablation
Procedure
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
166 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2011
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Completed Not applicable Interventional Results available

RADAR Clinical Trial

NCT03263702
Conditions
Persistent Atrial Fibrillation
Interventions
Computational Mapping Algorithm
Device
Lead sponsor
Vivek Reddy
Other
Eligibility
19 Years and older
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
4
States / cities
Denver, Colorado • Boston, Massachusetts • New York, New York
Conditions
Atrial Fibrillation, Atrial Fibrillation, Persistent, Atrial Fibrillation Paroxysmal, Arrhythmia, Arrhythmias, Cardiac, Atrial Flutter, Atrial Fibrillation, Paroxysmal or Persistent, Atrial Arrhythmia, Atrial Tachycardia
Interventions
Electrographic Flow (EGF) mapping and ablation of EGF-identified sources of Atrial Fibrillation, Electrographic Flow (EGF) mapping (no ablation)
Device
Lead sponsor
Cortex
Industry
Eligibility
18 Years to 80 Years
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
15
States / cities
Birmingham, Alabama • Phoenix, Arizona • Redwood City, California + 11 more