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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Augmented Intervention Clear all
Active, not recruiting Phase 3 Interventional Accepts healthy volunteers

Improved Diagnosis of Familial Hypercholesterolemia Across the Northland (ID-FH)

NCT05238519
View directory record Official record
Conditions
Familial Hypercholesterolemia, Cholesterol, Elevated, Genetic Disease
Interventions
Motivational interview (MI)
Behavioral
Lead sponsor
Essentia Health
Other
Eligibility
2 Years to 75 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
2
States / cities
Duluth, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 15, 2026 · Synced Sep 4, 2026, 2:25 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Voluntary Adjustments During Walking in Participants Post-stroke

NCT06034119
View directory record Official record
Conditions
Stroke
Interventions
Split belt treadmill, Biofeedback
Behavioral
Lead sponsor
Chapman University
Other
Eligibility
18 Years to 90 Years
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated Sep 24, 2025 · Synced Sep 4, 2026, 2:25 AM EDT
Completed Phase 1 Interventional

Varenicline as a Treatment for Methamphetamine Dependence

NCT01571167
View directory record Official record
Conditions
Methamphetamine Dependence, Methamphetamine Abuse, Substance Abuse
Interventions
Placebo, Varenicline
Drug
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years to 55 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 12, 2013 · Synced Sep 4, 2026, 2:25 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

An Exploratory Rectal Safety Study of Three Tenofovir Gel Formulations

NCT01575418
View directory record Official record
Conditions
HIV Prevention
Interventions
Rectal formulation (RF) of tenofovir 1% gel, Vaginal formulation (VF) of tenofovir 1% gel, Reduced glycerin vaginal formulation (RGVF) of tenofovir 1% gel, Radiolabeling of study drugs and semen
Drug · Radiation
Lead sponsor
Ian McGowan
Other
Eligibility
18 Years and older · Male only
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated May 7, 2014 · Synced Sep 4, 2026, 2:25 AM EDT
Completed Not applicable Interventional

Developing a Low-Intensity Primary Care Intervention for Anxiety Disorders

NCT02266446
View directory record Official record
Conditions
Anxiety Disorders
Interventions
Attention & Interpretation Modification
Behavioral
Lead sponsor
Brown University
Other
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Pawtucket, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jan 22, 2018 · Synced Sep 4, 2026, 2:25 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Eccentric Training Effects on Hamstrings Structure, Strength, and Sprint Performance

NCT05455346
View directory record Official record
Conditions
Exercise Training, Sport, Running, Ultrasound Imaging, Elastography, Healthy
Interventions
Ultrasound imaging, Hamstring Eccentric Strength Testing, Maximal 60 m Sprint, Romanian Deadlift, Nordic hamstring exercise
Diagnostic Test · Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 25 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Dec 20, 2023 · Synced Sep 4, 2026, 2:25 AM EDT
Recruiting Not applicable Interventional

Exposure-Based CBT for Avoidant/Restrictive Food Intake in Functional Dyspepsia

NCT05587127
View directory record Official record
Conditions
Avoidant/Restrictive Food Intake Disorder, Dyspepsia, Feeding and Eating Disorders, Cognitive Behavioral Therapy, Appetite Regulation, Functional Dyspepsia, Post-prandial Distress Syndrome, Behavioral Medicine
Interventions
Cognitive Behavioral Therapy
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 24, 2025 · Synced Sep 4, 2026, 2:25 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Does a Preoperative Bowel Regimen Change Time to First Bowel Movement After Robotic Sacral Colpopexy

NCT04197869
View directory record Official record
Conditions
Constipation, Post-Op Complication
Interventions
Polyethylene Glycol Powder
Drug
Lead sponsor
Northwell Health
Other
Eligibility
18 Years to 89 Years · Female only
Enrollment
71 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Bay Shore, New York
Source: ClinicalTrials.gov public record
Updated Dec 26, 2024 · Synced Sep 4, 2026, 2:25 AM EDT
Terminated Phase 1Phase 2 Interventional Results available

Project 4A: Inspiratory Muscle Training and Diaphragm Strength

NCT02367170
View directory record Official record
Conditions
Sepsis
Interventions
Bilateral phrenic nerve stimulation and measurement of transdiaphragmatic pressure, Midazolam, Volitional Measurement of Maximal Inspiratory Pressure (MIP), Inspiratory Muscle Strength Training (IMST), SHAM Inspiratory Muscle Strength Training (IMST), Diaphragm thickness measurement, Blood and Urine samples
Procedure · Drug · Device + 1 more
Lead sponsor
University of Florida
Other
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated May 6, 2018 · Synced Sep 4, 2026, 2:25 AM EDT
Terminated Not applicable Interventional Results available

Family Connections: Cultural Adaptation and Feasibility Testing for Rural Latino Communities

NCT04731506
View directory record Official record
Conditions
Childhood Obesity
Interventions
Family Connections
Behavioral
Lead sponsor
University of Nebraska
Other
Eligibility
6 Years and older
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Feb 5, 2026 · Synced Sep 4, 2026, 2:25 AM EDT
Terminated Not applicable Interventional Results available

Safety of Anti-Depressant for Chronic Obstructive Pulmonary Disease (SAD-COPD)

NCT02813447
View directory record Official record
Conditions
COPD, Anxiety, Depression, Stress, Interstitial Lung Disease
Interventions
Sertraline, Placebo
Drug
Lead sponsor
Duke University
Other
Eligibility
40 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 30, 2025 · Synced Sep 4, 2026, 2:25 AM EDT
Withdrawn Early Phase 1 Interventional Accepts healthy volunteers

Gender Differences in the Metabolic Effects of Uric Acid

NCT03076684
View directory record Official record
Conditions
Hyperuricemia
Interventions
low-fructose diet, Allopurinol
Other · Drug
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
40 Years to 70 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 16, 2019 · Synced Sep 4, 2026, 2:25 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Internet-based Intervention for Skin Self-Examination in Participants With Increased Risk for Melanoma

NCT03725449
View directory record Official record
Conditions
Dysplastic Nevus, Health Status Unknown, Melanoma, No Evidence of Disease
Interventions
Best Practice, mySmartCheck, Survey Administration
Other · Behavioral
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years to 89 Years
Enrollment
116 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
New Brunswick, New Jersey
Source: ClinicalTrials.gov public record
Updated Nov 13, 2022 · Synced Sep 4, 2026, 2:25 AM EDT
Not yet recruiting Not applicable Interventional

AI-Augmented Motivational Interviewing Training for Primary Care

NCT06597123
View directory record Official record
Conditions
Multiple Chronic Conditions, Patient Engagement, Burnout, Professional, Motivational Interviewing, Implicit Bias
Interventions
Basic AI (artificial intelligence)-Augmented Motivational Interviewing Training, Plus AI (artificial intelligence)-Augmented Motivational Interviewing Training
Behavioral
Lead sponsor
Wright State University
Other
Eligibility
21 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
2
States / cities
Dayton, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 18, 2024 · Synced Sep 4, 2026, 2:25 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

"GameDay Ready": Evaluating a Behavioral Weight Management Program for Black Men Living in the Rural South

NCT05530980
View directory record Official record
Conditions
Obesity, Physical Inactivity, Diet, Healthy
Interventions
GameDay Ready Program
Behavioral
Lead sponsor
University of South Carolina
Other
Eligibility
25 Years to 50 Years · Male only
Enrollment
7 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Feb 1, 2024 · Synced Sep 4, 2026, 2:25 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Motivation for Exercise: A Mood-Based Focus

NCT06706180
View directory record Official record
Conditions
Exercise Motivation
Interventions
Exercise for Mood video, Exercise for Fitness video
Other
Lead sponsor
Boston University Charles River Campus
Other
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 1, 2025 · Synced Sep 4, 2026, 2:25 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Three-Group Study to Examine the Efficacy of the Air up® Drinking System at Improving Hydration and Associated Health Outcomes

NCT06290479
View directory record Official record
Conditions
Water Intake
Interventions
Air Up® Peach Pod, Air Up® Orangeade Pod
Dietary Supplement
Lead sponsor
air up GmbH
Industry
Eligibility
18 Years to 50 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Santa Monica, California
Source: ClinicalTrials.gov public record
Updated Jul 18, 2024 · Synced Sep 4, 2026, 2:25 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

SOP Toolkit in Diverse Practices Implemented & Tested With RE-AIM

NCT01868334
View directory record Official record
Conditions
Adult Influenza Vaccinations, Adult PPSV Vaccinations, Adult Tdap/Td Vaccinations
Interventions
Pillar 1: Convenient Vaccination Services, Pillar 2: Patient notification, Pillar 3: Enhanced Office Systems, Pillar 4: Motivation
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
70,549 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
2
States / cities
Pittsburgh, Pennsylvania • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 5, 2023 · Synced Sep 4, 2026, 2:25 AM EDT
Completed Not applicable Interventional

Transrectal NOTES Appendectomy - Feasibility Study

NCT01189916
View directory record Official record
Conditions
Appendectomy, Laparoscopic, Endoscopy
Interventions
Endoscopically assisted Appendectomy Surgery
Procedure
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 12, 2015 · Synced Sep 4, 2026, 2:25 AM EDT
Completed Phase 2 Interventional Results available

Vitamin D to Prevent Autism in Newborn Siblings

NCT01366885
View directory record Official record
Conditions
Autistic Disorder
Interventions
Vitamin D3
Drug
Lead sponsor
Oregon Health and Science University
Other
Eligibility
20 Years to 44 Years · Female only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2016
U.S. locations
1
States / cities
Oregon City, Oregon
Source: ClinicalTrials.gov public record
Updated Jun 13, 2016 · Synced Sep 4, 2026, 2:25 AM EDT
Completed Not applicable Interventional

Men and Providers Preventing Suicide (MAPS)

NCT02986113
View directory record Official record
Conditions
Suicidal Intention, Suicidal Ideation, Suicide, Attempted
Interventions
MAPS tailored multimedia patient activation program, Sleep hygiene video, Telephone evidence-based follow-up care, Commitment to Living for Primary Care
Behavioral
Lead sponsor
University of California, Davis
Other
Eligibility
35 Years to 64 Years · Male only
Enrollment
93 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
2
States / cities
Palo Alto, California • Sacramento, California
Source: ClinicalTrials.gov public record
Updated Oct 29, 2019 · Synced Sep 4, 2026, 2:25 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Computer-based Intervention to Augment Home Visitation Services: The E-Parenting Project

NCT01304719
View directory record Official record
Conditions
Child Maltreatment
Interventions
Computer Assisted Healthy Families America Home Visitation, Healthy Families America Home Visitation
Behavioral
Lead sponsor
Centers for Disease Control and Prevention
Federal
Eligibility
18 Years and older · Female only
Enrollment
413 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2011
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated May 14, 2013 · Synced Sep 4, 2026, 2:25 AM EDT
Completed Not applicable Interventional

Evaluating Household Visits and Small Groups to Increase Contraception Use Among Married Adolescent Girls in Rural Niger

NCT03226730
View directory record Official record
Conditions
Contraception
Interventions
Household Visits, Small Groups
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
13 Years and older
Enrollment
2,898 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Feb 23, 2023 · Synced Sep 4, 2026, 2:25 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Supporting Mothers of Preterm Infants

NCT03013660
View directory record Official record
Conditions
PreTerm Birth
Interventions
Limited Financial Support
Other
Lead sponsor
Tufts Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
68 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
2
States / cities
Boston, Massachusetts • Lowell, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 8, 2019 · Synced Sep 4, 2026, 2:25 AM EDT