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ClinicalTrials.gov public records Last synced Oct 30, 2026, 10:58 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1033–1056 of 1,213 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Bilateral Clear all
Completed Phase 2 Interventional Results available

LYR-220 for Adult Subjects With Chronic Rhinosinusitis (BEACON Study)

NCT05035654
View directory record Official record
Conditions
Chronic Sinusitis, Chronic Rhinosinusitis (Diagnosis)
Interventions
LYR-220 Design 1 (Part 1 only), LYR-220 Design 2 (Part 1 and Part 2), Bilateral sham procedure control (Part 2)
Drug
Lead sponsor
Lyra Therapeutics
Industry
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
22
States / cities
Carlsbad, California • La Mesa, California • Roseville, California + 18 more
Source: ClinicalTrials.gov public record
Updated Dec 17, 2024 · Synced Oct 30, 2026, 10:58 AM EDT
Active, not recruiting Phase 3 Interventional

A Clinical Study Evaluating The Benefit of Adding Rucaparib to Enzalutamide for Men With Metastatic Prostate Cancer That Has Become Resistant To Testosterone-Deprivation Therapy

NCT04455750
View directory record Official record
Conditions
Castration-Resistant Prostate Carcinoma, Metastatic Prostate Adenocarcinoma, Stage IV Prostate Cancer AJCC v8, Stage IVA Prostate Cancer AJCC v8, Stage IVB Prostate Cancer AJCC v8
Interventions
Enzalutamide, Rucaparib camsylate, Placebo, Leuprolide Acetate, Goserelin Acetate, Degarelix, Quality-of-Life Assessment, Questionnaire Administration
Drug · Other
Lead sponsor
Alliance for Clinical Trials in Oncology
Other
Eligibility
18 Years and older · Male only
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
414
States / cities
Anchorage, Alaska • Phoenix, Arizona • Hot Springs, Arkansas + 298 more
Source: ClinicalTrials.gov public record
Updated Feb 5, 2026 · Synced Oct 30, 2026, 10:58 AM EDT
Recruiting Not applicable Interventional

Prediction of Anxiety and Memory State

NCT06551090
View directory record Official record
Conditions
Anxiety, Memory, Epilepsy
Interventions
CAMERA (Context-Aware Multimodal Ecological Research and Assessment)
Other
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 55 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 28, 2026 · Synced Oct 30, 2026, 10:58 AM EDT
Enrolling by invitation Phase 2 Interventional

Hernia Abd Wall Recons - BDE vs Exparel

NCT07518238
View directory record Official record
Conditions
BDE for Hernia Patients, Exparel for Hernia Patients
Interventions
BDE Injectable Drug, Exparel Injectable Drug
Drug
Lead sponsor
Baylor Research Institute
Other
Eligibility
18 Years and older
Enrollment
128 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Apr 8, 2026 · Synced Oct 30, 2026, 10:58 AM EDT
Not listed Not applicable Interventional

Dry Needling Effects on Cortical Excitability

NCT05111691
View directory record Official record
Conditions
Low Back Pain
Interventions
Dry needling
Procedure
Lead sponsor
Texas Woman's University
Other
Eligibility
18 Years to 65 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jul 6, 2022 · Synced Oct 30, 2026, 10:58 AM EDT
Recruiting Not applicable Interventional

Analgesic Response to Opioids in Patients With Fibromyalgia After Conventional Acupuncture Versus Sham Acupuncture

NCT06571110
View directory record Official record
Conditions
Fibromyalgia
Interventions
Traditional Acupuncture, Sham Acupuncture
Procedure
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years to 80 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated Jun 15, 2026 · Synced Oct 30, 2026, 10:58 AM EDT
Completed Not applicable Interventional Results available

Randomized Contralateral Clinical Trial With Single-piece (SN60WF) vs. Three Piece (MA60AC) AcrySof Intraocular Lenses (IOLs) on Development of Posterior Chamber Opacification (PCO).

NCT00758745
View directory record Official record
Conditions
Cataract
Interventions
Model SN60WF, Model MA60AC
Device
Lead sponsor
Alcon Research
Industry
Eligibility
50 Years and older
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Aug 19, 2014 · Synced Oct 30, 2026, 10:58 AM EDT
Terminated Not applicable Interventional Results available

Effects of Using the Duracore Splinting Device on Patient Outcomes Related to Chest Trauma

NCT04909463
View directory record Official record
Conditions
Rib Fractures, Rib Fracture Multiple
Interventions
Chest Splint
Device
Lead sponsor
CommonSpirit Health
Other
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Colorado Springs, Colorado
Source: ClinicalTrials.gov public record
Updated May 14, 2025 · Synced Oct 30, 2026, 10:58 AM EDT
Not listed Not applicable Interventional

Opioid Counseling in Pain Management

NCT03985358
View directory record Official record
Conditions
Pain, Postoperative
Interventions
Opioid counseling plus standard of care instructions
Other
Lead sponsor
University of South Florida
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Sep 29, 2021 · Synced Oct 30, 2026, 10:58 AM EDT
Recruiting Phase 1Phase 2 Interventional

tDCS for Late-Life Depression

NCT07657234
View directory record Official record
Conditions
Late Life Depression (LLD), Depression - Major Depressive Disorder
Interventions
High-intensity (6 mA) transcranial direct current stimulation (tDCS)
Device
Lead sponsor
Andre Russowsky Brunoni
Other
Eligibility
60 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Sep 25, 2026 · Synced Oct 30, 2026, 10:58 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Optimizing Noisy Galvanic Vestibular Stimulation Frequency Range for Enhancing Vestibular Perception and Manual Control Performance

NCT07730398
View directory record Official record
Conditions
Vestibular Function Tests, Sensorimotor Performance
Interventions
Low-frequency noisy galvanic vestibular stimulation (nGVS), High-frequency noisy galvanic vestibular stimulation (nGVS)
Device
Lead sponsor
National Aeronautics and Space Administration (NASA)
Federal
Eligibility
22 Years and older
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 28, 2026 · Synced Oct 30, 2026, 10:58 AM EDT
Terminated Not applicable Interventional Results available

A Study to Detect Progression of Mass Effect From Unilateral Brain Lesions

NCT04745884
View directory record Official record
Conditions
Non-traumatic Hemispheric Brain Lesions
Interventions
Non-invasive bilateral monitoring of ICP waveform
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 6, 2026 · Synced Oct 30, 2026, 10:58 AM EDT
Not listed Not applicable Interventional

Are Superficial Parasternal Intercostal Plane (SPIP) Blocks With Bupivacaine and With or Without Adjuvants Helpful for Post-operative Pain After Coronary Artery Bypass Grafting?

NCT05003765
View directory record Official record
Conditions
Post-operative Pain Management
Interventions
Bupivacaine 0.25% Injectable Solution, Bupivacaine 0.25% Injectable Solution, Magnesium Sulfate 200 mg, Bupivacaine 0.25% Injectable Solution, Magnesium Sulfate 200 mg, Buprenorphine 300 mcg
Drug
Lead sponsor
Wayne State University
Other
Eligibility
18 Years to 100 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Pontiac, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 12, 2021 · Synced Oct 30, 2026, 10:58 AM EDT
Completed Phase 1Phase 2 Interventional Results available

Pilot Study of the Evaluation of Subconjunctival Sirolimus in the Treatment of Bilateral GA Associated With AMD

NCT00766649
View directory record Official record
Conditions
Age-Related Macular Degeneration
Interventions
Sirolimus
Drug
Lead sponsor
National Eye Institute (NEI)
NIH
Eligibility
55 Years and older
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 14, 2020 · Synced Oct 30, 2026, 10:58 AM EDT
Recruiting Not applicable Interventional

Understanding the Neural Underpinnings of Risk-Taking Behavior in Psychiatric Disease

NCT07896343
View directory record Official record
Conditions
Depression - Major Depressive Disorder
Interventions
Approach-Avoidance Decision-Making Task
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Oct 27, 2026 · Synced Oct 30, 2026, 10:58 AM EDT
Not listed Not applicable Interventional

SToP: Venous Thromboembolism Screening in the Trauma Population

NCT02978950
View directory record Official record
Conditions
Venous Thromboembolism, Deep Vein Thrombosis, Trauma, Multiple
Interventions
Duplex ultrasound surveillance, No ultrasound surveillance
Other
Lead sponsor
Intermountain Health Care, Inc.
Other
Eligibility
18 Years and older
Enrollment
2,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Murray, Utah
Source: ClinicalTrials.gov public record
Updated Nov 29, 2018 · Synced Oct 30, 2026, 10:58 AM EDT
Withdrawn Not applicable Interventional

Blood Flow Restriction Training Following Glenoid Labral Repair

NCT03675620
View directory record Official record
Conditions
Glenoid Labrum Tear
Interventions
BFR, Standard Rehabilitation
Device · Other
Lead sponsor
Andrews Research & Education Foundation
Other
Eligibility
18 Years to 55 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Gulf Breeze, Florida
Source: ClinicalTrials.gov public record
Updated Feb 6, 2024 · Synced Oct 30, 2026, 10:58 AM EDT
Completed Not applicable Interventional

Glaucoma Management in the African-Derived Developing World Using Trabeculoplasty

NCT02375009
View directory record Official record
Conditions
Glaucoma
Interventions
Selective laser trabeculoplasty
Procedure
Lead sponsor
West Virginia University
Other
Eligibility
30 Years and older
Enrollment
129 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Morgantown, West Virginia
Source: ClinicalTrials.gov public record
Updated Jun 18, 2021 · Synced Oct 30, 2026, 10:58 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Assessing Speech Perception and Amplification Benefit During Infancy

NCT05653999
View directory record Official record
Conditions
Hearing Loss, Children With Hearing Differences, Amplification, Speech Perception
Interventions
Hearing Aids
Device
Lead sponsor
University of Colorado, Denver
Other
Eligibility
6 Months to 36 Months
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Jun 4, 2025 · Synced Oct 30, 2026, 10:58 AM EDT
Completed Phase 2 Interventional Results available

Double-Blind, Multicenter, Sham Surgery Controlled Study of CERE-120 in Subjects With Idiopathic Parkinson's Disease

NCT00400634
View directory record Official record
Conditions
Idiopathic Parkinson's Disease
Interventions
CERE-120 (Adeno-Associated Virus Serotype 2 [AAV2]-Neurturin [NTN]), Sham Surgery
Drug · Procedure
Lead sponsor
Sangamo Therapeutics
Industry
Eligibility
35 Years to 75 Years
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
9
States / cities
Birmingham, Alabama • San Francisco, California • Chicago, Illinois + 6 more
Source: ClinicalTrials.gov public record
Updated Nov 10, 2022 · Synced Oct 30, 2026, 10:58 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Feasibility Study: Evaluation of the Ulthera® System for Treatment of the Knees

NCT01708434
View directory record Official record
Conditions
Skin Laxity
Interventions
Ulthera® System
Device
Lead sponsor
Ulthera, Inc
Industry
Eligibility
30 Years to 65 Years · Female only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Nov 24, 2017 · Synced Oct 30, 2026, 10:58 AM EDT
Not yet recruiting Phase 4 Interventional

Clinical Evaluation of Visual Performance, Spectacle Independence, and Patient Satisfaction With TECNIS PureSee Mini-Monovision and TECNIS PureSee-TECNIS Odyssey Mix-Match

NCT07860567
View directory record Official record
Conditions
Presbyopia Correction, Presbyopia, Dysphotopsia, Visual Acuity
Interventions
TECNIS PureSee IOL (Model DEN00V/DET150), TECNIS Odyssey IOL (Model DRN00V/DRT150)
Device
Lead sponsor
Dr. Daniel H. Chang, MD
Other
Eligibility
22 Years and older
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Bakersfield, California
Source: ClinicalTrials.gov public record
Updated Oct 6, 2026 · Synced Oct 30, 2026, 10:58 AM EDT
Recruiting Not applicable Interventional

CAAAs, TAAAs, Aortic Arch Aneurysms or Dissections With Fenestrated/Branched Stent Graft

NCT02089607
View directory record Official record
Conditions
Complex Abdominal Aortic Aneurysm, Thoracoabdominal Aortic Aneurysm, Aortic Arch Aneurysm, Aortic Arch Dissection
Interventions
CAAA and TAAA Arm, Aortic Arch Aneurysm Arm
Device
Lead sponsor
Gustavo S Oderich
Other
Eligibility
18 Years and older
Enrollment
760 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2032
U.S. locations
3
States / cities
Rochester, Minnesota • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 27, 2026 · Synced Oct 30, 2026, 10:58 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

The Effectiveness of Emergency Room Protocols for Treating Hyperthermia

NCT07433036
View directory record Official record
Conditions
Hyperthermia
Interventions
Passive cooling, Cooling packs, Ice sheets, Body bag cooling, Cold water immersion
Procedure
Lead sponsor
University of Colorado, Colorado Springs
Other
Eligibility
18 Years to 65 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Colorado Springs, Colorado
Source: ClinicalTrials.gov public record
Updated Feb 25, 2026 · Synced Oct 30, 2026, 10:58 AM EDT