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ClinicalTrials.gov public records Last synced Oct 19, 2026, 10:28 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 25–35 of 35 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Biofinity Clear all
Completed Not applicable Interventional Results available

Three Daily Wear Monthly Replacement Silicone Hydrogel Contact Lenses With Two Multi-purpose Disinfecting Solution Combinations

NCT04789382
View directory record Official record
Conditions
Refractive Errors
Interventions
LID018869+RepleniSH, LID018869+Biotrue, Biofinity+RepleniSH, PV+Biotrue
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Maitland, Florida
Source: ClinicalTrials.gov public record
Updated May 25, 2022 · Synced Oct 19, 2026, 10:28 PM EDT
Completed Not applicable Interventional Results available

Clinical Performance of a Silicone Hydrogel Contact Lens Following Six Nights of Extended Wear

NCT03614130
View directory record Official record
Conditions
Refractive Errors
Interventions
LID011121 contact lens, Comfilcon A contact lens
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
2
States / cities
Johns Creek, Georgia • Brentwood, Tennessee
Source: ClinicalTrials.gov public record
Updated Sep 30, 2021 · Synced Oct 19, 2026, 10:28 PM EDT
Completed Not applicable Interventional Results available

Bifocal Lenses In Nearsighted Kids

NCT02255474
View directory record Official record
Conditions
Refractive Errors
Interventions
Biofinity Multifocal D +1.50 add, Biofinity Multifocal D +2.50 add, Biofinity
Device
Lead sponsor
Ohio State University
Other
Eligibility
7 Years to 11 Years
Enrollment
294 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
2
States / cities
Columbus, Ohio • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 10, 2021 · Synced Oct 19, 2026, 10:28 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluating Accommodative Responses of Soft Contact Lenses for Myopia Control

NCT03635528
View directory record Official record
Conditions
Visual Acuity
Interventions
Test Lens 1, Test Lens 2, Test Lens 3, Test Lens 4, Test Lens 5, Control Lens 1, Control Lens 2
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
7 Years to 25 Years
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated Aug 20, 2020 · Synced Oct 19, 2026, 10:28 PM EDT
Completed Not applicable Interventional Results available

Clinical Performance of a Silicone Hydrogel Contact Lens Following One Night of Extended Wear

NCT03560141
View directory record Official record
Conditions
Refractive Errors
Interventions
LID011121 contact lens, Comfilcon A contact lens
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Johns Creek, Georgia
Source: ClinicalTrials.gov public record
Updated Jul 28, 2021 · Synced Oct 19, 2026, 10:28 PM EDT
Completed Not applicable Interventional Results available

Assessment of an Investigational Frequent Replacement Silicone Hydrogel Lens

NCT04085328
View directory record Official record
Conditions
Refractive Ametropia
Interventions
LID015385 soft contact lenses, Comfilcon A soft contact lenses
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
675 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
42
States / cities
Campbell, California • Fullerton, California • Los Angeles, California + 34 more
Source: ClinicalTrials.gov public record
Updated Jun 13, 2023 · Synced Oct 19, 2026, 10:28 PM EDT
Completed No phase listed Observational

Air Optix Plus HydraGlyde Multifocal Daily/Extended Wear Contact Lenses

NCT05886894
View directory record Official record
Conditions
Refractive Errors
Interventions
Lotrafilcon B multifocal soft contact lenses, Comfilcon A multifocal soft contact lenses
Device
Lead sponsor
Alcon Research
Industry
Eligibility
40 Years and older
Enrollment
351 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
8
States / cities
San Diego, California • Jacksonville, Florida • Miami, Florida + 5 more
Source: ClinicalTrials.gov public record
Updated Aug 14, 2025 · Synced Oct 19, 2026, 10:28 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Accommodative Behaviors in Multifocal Contact Lenses

NCT06064617
View directory record Official record
Conditions
Accommodation Disorder
Interventions
Center-Near (+2.50D) Coopervision Biofinity Multifocal Contact Lens, Center Distance (+2.50 D) Coopervision Biofinity Multifocal Contact Lens
Device
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 30 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 8, 2026 · Synced Oct 19, 2026, 10:28 PM EDT
Completed Not applicable Interventional Results available

Clinical Evaluation of a Daily Wear Frequent Replacement Silicone Hydrogel Lens

NCT03920280
View directory record Official record
Conditions
Refractive Errors
Interventions
LID015385 contact lenses, Comfilcon A soft contact lenses, CLEAR CARE
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
8
States / cities
Maitland, Florida • Orlando, Florida • Pensacola, Florida + 5 more
Source: ClinicalTrials.gov public record
Updated Jul 28, 2022 · Synced Oct 19, 2026, 10:28 PM EDT
Completed Not applicable Interventional Results available

Clinical Validation Study of Comfilcon A Multifocal Toric Contact Lenses

NCT03417557
View directory record Official record
Conditions
Presbyopia
Interventions
Comfilcon A lens (test), Omafilcon B lens (control)
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
40 Years to 75 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated May 4, 2020 · Synced Oct 19, 2026, 10:28 PM EDT
Completed Not applicable Interventional Results available

Dispensing Evaluation of a Galyfilcon A Prototype Lens and a Marketed Contact Lens

NCT01180985
View directory record Official record
Conditions
Myopia
Interventions
galyfilcon A prototype lens, comfilcon A
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 39 Years
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010
U.S. locations
4
States / cities
Jacksonville, Florida • Orlando, Florida • Fincastle, Virginia + 1 more
Source: ClinicalTrials.gov public record
Updated Jun 19, 2018 · Synced Oct 19, 2026, 10:28 PM EDT