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Showing 361–384 of 531 matching trials from the local directory fallback.
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Blood Flow Restriction Resistance Exercise and Cardiac Cycle Dynamics

NCT07344740
Conditions
Cardiac
Interventions
Blood flow restriction resistance exercise
Behavioral
Lead sponsor
Montclair State University
Other
Eligibility
18 Years to 50 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Montclair, New Jersey
Not yet recruiting Phase 4 Interventional

Rocklatan Retinal Perfusion OCT Study

NCT07174401
Conditions
Glaucoma
Interventions
Rocklatan eye drops will be instilled nightly in one eye diagnosed with glaucoma for up to 12 months., Two optical coherence tomography (OCT) devices will be used to assess blood flow changes.
Drug · Device
Lead sponsor
Oregon Health and Science University
Other
Eligibility
21 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Portland, Oregon
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Reducing Self-Dehumanization to Examine Oxytocin and Suicide Risk

NCT06713473
Conditions
Control Intervention, Rehumanization Intervention
Interventions
Blood Draw, Clinical Interview, Control Intervention, Rehumanized Intervention, Self-Report Measures
Other · Diagnostic Test
Lead sponsor
Florida State University
Other
Eligibility
18 Years to 40 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Tallahassee, Florida
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

The Influences of Blood Flow Restriction on Leg Press

NCT07052227
Conditions
Delfi Cuff, Fitcuff, Placebo - Control
Interventions
Control, Delfi blood flow restriction cuff, Fitcuffs
Other · Device
Lead sponsor
Salisbury University
Other
Eligibility
18 Years to 40 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Salisbury, Maryland
Conditions
Endometriosis
Interventions
The Mitomic Endometriosis Test (MET) blood test for early detection of endometriosis
Diagnostic Test
Lead sponsor
Pearsanta, Inc
Industry
Eligibility
Female only
Enrollment
1,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2030
U.S. locations
1
States / cities
Richmond, Virginia
Conditions
Blood Pressure
Interventions
Non-invasive Blood Pressure Monitor
Device
Lead sponsor
Vena Vitals
Industry
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Not yet recruiting No phase listed Observational Accepts healthy volunteers

Performance of the Acoustic Based CADScor System in Coronary Artery Disease

NCT06655779
Conditions
Angina (stable), Coronary Artery Disease
Interventions
Acoustic Detection of Blood Flow
Diagnostic Test
Lead sponsor
INTEGRIS Baptist Medical Center
Other
Eligibility
30 Years and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Conditions
Breast Cancer, Breast Cancer Female
Interventions
Blood test
Diagnostic Test
Lead sponsor
Immunis.AI
Industry
Eligibility
18 Years and older · Female only
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Durham, North Carolina
Conditions
Chronic Granulomatous Disease
Interventions
Alemtuzumab, Allogeneic peripheral blood stem cell, Busulfan, Cyclophosphamide, Sirolimus, Total Body Irradiation
Drug · Biological · Radiation
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
4 Years to 65 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2034
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Lung Non-Small Cell Carcinoma
Interventions
Blood Oxygen Level Dependent Imaging, Papaverine Hydrochloride, Stereotactic Body Radiation Therapy
Procedure · Drug · Radiation
Lead sponsor
Ohio State University Comprehensive Cancer Center
Other
Eligibility
18 Years and older
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2027
U.S. locations
1
States / cities
Columbus, Ohio
Conditions
Chronic Granulomatous Disease Transplant
Interventions
Alemtuzumab, Busulfan, Cyclophosphamide, Peripheral blood stem cells, Sirolimus, Total Body Irradiation
Drug · Biological · Radiation
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
4 Years to 65 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2028
U.S. locations
1
States / cities
Bethesda, Maryland
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Assessment of Antibodies and Inflammatory Markers in Postural Tachycardia Syndrome

NCT02196376
Conditions
Postural Orthostatic Tachycardia Syndrome
Interventions
History, Physical, Questionnaires, blood draw
Other · Behavioral
Lead sponsor
Vanderbilt University
Other
Eligibility
13 Years to 80 Years
Enrollment
212 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2029
U.S. locations
1
States / cities
Nashville, Tennessee
Active, not recruiting Phase 2 Interventional Accepts healthy volunteers

Pilot Study of Reduced-Intensity Hematopoietic Stem Cell Transplant of DOCK8 Deficiency

NCT01176006
Conditions
DOCK8 Deficiency
Interventions
Bone Marrow Harvest Procedure, Busulfan (Busulfex), Cyclophosphamide(CTX, Cytoxan), Donor peripheral blood stem cell mobiliation and collection, Fludarabine(Fludara, Berlex Laboratories), Reduced-intensity hematopoietic stem cell, Total Body Irradiation (TBI)
Procedure · Drug
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
4 Years to 120 Years
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2028
U.S. locations
1
States / cities
Bethesda, Maryland
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

The Effect of Nutrient Sequencing in Healthy Adults

NCT07873437
Conditions
Pre Diabetes
Interventions
Diet History Questionnaire, Finger Prick- Blood Glucose, Physical Activity Assessment, Whole Blood Draw
Behavioral · Procedure
Lead sponsor
Cornell University
Other
Eligibility
18 Years to 35 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Ithaca, New York
Conditions
Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Chronic Myelomonocytic Leukemia, Myelodysplastic Syndrome, Myeloproliferative Neoplasm, Primary Myelofibrosis, Secondary Myelofibrosis
Interventions
Cyclophosphamide, Itacitinib, Peripheral Blood Stem Cell Transplantation, Quality-of-Life Assessment, Tacrolimus
Drug · Procedure · Other
Lead sponsor
City of Hope Medical Center
Other
Eligibility
Up to 80 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Duarte, California
Active, not recruiting Phase 2 Interventional Results available

RANKL Inhibition and Mammographic Breast Density

NCT04067726
Conditions
Dense Breasts
Interventions
Blood draw, Calcium, Core needle biopsy, Denosumab, Placebo, Vitamin D3
Procedure · Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
40 Years and older · Female only
Enrollment
210 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2027
U.S. locations
1
States / cities
St Louis, Missouri
Conditions
Breast Cancer
Interventions
Blood draw, CPET Procedures, Harvard Health Professionals survey, Research Tissue sampling, stool sample
Other · Behavioral · Procedure
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
21 Years to 80 Years · Female only
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2027
U.S. locations
7
States / cities
Basking Ridge, New Jersey • Middletown, New Jersey • Montvale, New Jersey + 4 more
Conditions
Acute Myeloid Leukemia, Myelodysplastic Syndrome
Interventions
Allogeneic Hematopoietic Stem Cell Transplantation, Busulfan, Cladribine, Fludarabine Phosphate, Laboratory Biomarker Analysis, Peripheral Blood Stem Cell Transplantation, Pharmacological Study, Venetoclax
Procedure · Drug · Other
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
2 Years to 70 Years
Enrollment
116 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2027
U.S. locations
1
States / cities
Houston, Texas
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Vital Signs Blood Pressure Trial

NCT06272318
Conditions
Blood Pressure, Cardiovascular Diseases, Hypertension
Interventions
Blood Pressure Cuff, EKG, PPG
Other
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 64 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Stanford, California
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Lysine-specific Demethylase 1 and Salt-sensitivity in Humans

NCT03029806
Conditions
Healthy Subjects
Interventions
Aldosterone response to AngII LS, Renal blood flow response to salt, Vascular Stiffness
Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
25 Years to 45 Years
Enrollment
88 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Acute Hepatic Porphyria, Postural Orthostatic Tachycardia Syndrome
Interventions
Autonomic Function Testing, Blood laboratory Testing, Genetic Testing, Urine Testing
Diagnostic Test
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
70 participants
Timeline
2022 – 2026
U.S. locations
1
States / cities
Nashville, Tennessee
Conditions
Pancreatic Cancer
Interventions
Blood Sample Collection, Data Collection, Medical Image Collection, Tissue Sample Collection
Other
Lead sponsor
H. Lee Moffitt Cancer Center and Research Institute
Other
Eligibility
18 Years and older
Enrollment
185 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
2
States / cities
Tampa, Florida • Jackson, Mississippi
Conditions
Pancreatic Cancer, Pancreatic Cyst
Interventions
Blood Sample collection, Data collection, Tissue sample collection
Other
Lead sponsor
H. Lee Moffitt Cancer Center and Research Institute
Other
Eligibility
18 Years and older
Enrollment
1,274 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
3
States / cities
Lakewood Rch, Florida • Miami, Florida • Tampa, Florida
Conditions
Metastatic Castration-resistant Prostate Cancer, Prostate Cancer
Interventions
Blood Samples, Enzalutamide, FOR46, Pegfilgrastim
Procedure · Biological · Drug
Lead sponsor
Rahul Aggarwal
Other
Eligibility
18 Years and older · Male only
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
San Francisco, California