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Showing 25–44 of 20 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Brain Blood Flow Tests Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

Insulin Resistance in Adolescents

NCT04089332
View directory record Official record
Conditions
Insulin Resistance
Interventions
Oral Glucose Tolerance Test (OGTT), 3 Tesla MRI, Intravenous Catheter, Cognitive Tests
Other · Device
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
12 Years to 18 Years
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Sep 4, 2024 · Synced Sep 24, 2026, 4:06 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Mechanisms of Cerebrovascular Control

NCT02936687
View directory record Official record
Conditions
Metabolic Syndrome X
Interventions
NOS Inhibition, ET-1 Inhibition, NOS Inhibition Placebo, 3 Tesla MRI, Intravenous Catheter, Oral Glucose Tolerance Test, ET-1 Inhibition Placebo
Drug · Device · Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 45 Years
Enrollment
59 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Oct 17, 2021 · Synced Sep 24, 2026, 4:06 PM EDT
Withdrawn Not applicable Interventional

The Effect of Atrial Fibrillation Hemodynamics on Regulation of Cerebral Blood Flow

NCT00745602
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
non-invasive testing
Procedure
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jan 8, 2019 · Synced Sep 24, 2026, 4:06 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Development of a Clinically-relevant Test for Assessment of Cerebral Vascular Function

NCT04336852
View directory record Official record
Conditions
Cerebrovascular Disorders, Cerebrovascular Disease
Interventions
Flow mediated dilation (brachial and femoral arteries), Cerebral vascular reactivity to carbon dioxide (CO2), Cerebral vascular function test
Procedure
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years to 80 Years
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
2
States / cities
Chicago, Illinois • Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated May 19, 2025 · Synced Sep 24, 2026, 4:06 PM EDT
Terminated No phase listed Observational Results available

Variability in Transcranial Doppler Technique in Neuro-Critical Care Patients

NCT04583163
View directory record Official record
Conditions
Cerebral Aneurysm, Stroke, Vasospasm, Cerebral, Subarachnoid Hemorrhage, Aneurysmal, Aneurysmal Subarachnoid Hemorrhage, Cerebral Ischemia
Interventions
Transcranial Doppler
Diagnostic Test
Lead sponsor
Hackensack Meridian Health
Other
Eligibility
18 Years and older
Enrollment
3 participants
Timeline
2020 – 2022
U.S. locations
1
States / cities
Hackensack, New Jersey
Source: ClinicalTrials.gov public record
Updated Apr 14, 2025 · Synced Sep 24, 2026, 4:06 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Neuroimaging of Dystonia

NCT02046447
View directory record Official record
Conditions
Primary Cervical Dystonia, DYT 1 Dystonia
Interventions
Primary Cervical Dystonia (Trihexyphenidyl), Controls Primary Cervical Dystonia (Trihexyphenidyl), DYT 1 Dystonia (Healthy Control), DYT 1 Dystonia
Drug · Other
Lead sponsor
University of Florida
Other
Eligibility
7 Years to 70 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Dec 21, 2017 · Synced Sep 24, 2026, 4:06 PM EDT
Recruiting No phase listed Observational

Identifying Cerebral Hemodynamic Patterns in Mood Disorders and Mild Cognitive Impairment: A Functional Near-Infrared Spectroscopy (fNIRS) Study

NCT06897670
View directory record Official record
Conditions
Major Depressive Disorder, Bipolar Disorder, Mild Cognitive Impairment
Interventions
Observational assessment using functional near-infrared spectroscopy (fNIRS), a noninvasive, portable brain imaging tool that measures changes in brain blood flow and oxygen levels.
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
200 participants
Timeline
2025 – 2028
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 28, 2026 · Synced Sep 24, 2026, 4:06 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

PCOS and Brain Health

NCT07727512
View directory record Official record
Conditions
PCOS
Interventions
MRI Visit, Laboratory Visit
Device · Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Aug 20, 2026 · Synced Sep 24, 2026, 4:06 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

COPD-Related Physiology and the Brain

NCT03269721
View directory record Official record
Conditions
Pulmonary Disease, Chronic Obstructive (COPD), Cognitive Impairment
Interventions
Neuropsychological Assessment, Spirometry, Arterial Blood Gas, Diffusion Capacity of the Lung for Carbon Monoxide, 6 Minute Walk Test, Systemic Vascular Measures, Blood Biomarkers, Symptom Questionnaire Measures, Brain MRI
Behavioral · Procedure · Diagnostic Test + 1 more
Lead sponsor
Karin Hoth
Other
Eligibility
30 Years to 85 Years
Enrollment
170 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2025
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Dec 23, 2025 · Synced Sep 24, 2026, 4:06 PM EDT
Terminated Phase 2 Interventional Accepts healthy volunteers

Cerebrovascular Reactivity Assessed With fNIRS as a Biomarker of TCVI After Acute Traumatic Brain Injury in Military

NCT04058132
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Sildenafil Citrate 50Mg Tab, functional Near-infrared Spectroscopy (fNIRS), Carbon Dioxide (CO2) 5%, Neuropsychological Assessments, Gadolinium contrast infusion, Blood sample collection for research purposes, Structural brain Magnetic Resonance Imaging (MRI
Drug · Device · Other + 1 more
Lead sponsor
Uniformed Services University of the Health Sciences
Federal
Eligibility
18 Years to 55 Years
Enrollment
1 participant
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 27, 2024 · Synced Sep 24, 2026, 4:06 PM EDT
Completed No phase listed Observational

Prematurity-Related Ventilatory Control

NCT03464396
View directory record Official record
Conditions
Respiratory Control in Premature Infants
Interventions
Bedside Physiology study, Carotid Body Function Test, Room Air Challenge, Hypoxia Challenge Test, Effects of Nasal Cannula Flow, Magnetic Resonance Imaging, Echocardiogram, Blood Sample
Other · Diagnostic Test
Lead sponsor
Washington University School of Medicine
Other
Eligibility
1 Day to 28 Days
Enrollment
177 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jan 30, 2023 · Synced Sep 24, 2026, 4:06 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Stroke and Traumatic Acute Brain Injury Line Indicator System for Emergent Recognition (STABILISER-I)

NCT02514902
View directory record Official record
Conditions
Ischemic Stroke, Hemorrhagic Stroke, Traumatic Brain Injury
Interventions
Lateral Flow Device
Device
Lead sponsor
Justin Fraser
Other
Eligibility
21 Years to 85 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Feb 22, 2017 · Synced Sep 24, 2026, 4:06 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Brain Health in Transgender Adults

NCT07624747
View directory record Official record
Conditions
Gender Dysphoria
Interventions
Magnetic Resonance Imaging, Cognition and Health Tests, Optional Exercise Test
Device · Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 45 Years
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jun 2, 2026 · Synced Sep 24, 2026, 4:06 PM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Cerebral Blood Flow and Childhood Obstructive Sleep Apnea

NCT02995837
View directory record Official record
Conditions
Obstructive Sleep Apnea Syndrome
Interventions
Sleep Study, Neurocognitive Testing, CBF During Wakefulness, CBF During Sleep
Other
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
6 Years to 12 Years
Enrollment
47 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 8, 2024 · Synced Sep 24, 2026, 4:06 PM EDT
Not yet recruiting Early Phase 1 Interventional Accepts healthy volunteers

Human Cerebrovascular Blood Flow and Sex Differences in Metabolic Syndrome

NCT07218653
View directory record Official record
Conditions
Metabolic Syndrome
Interventions
Indomethacin, Placebo, MRI
Drug · Diagnostic Test
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 45 Years
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2031
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Aug 25, 2026 · Synced Sep 24, 2026, 4:06 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Coagulation/Complement Activation and Cerebral Hypoperfusion in Relapsing-remitting Multiple Sclerosis

NCT04380220
View directory record Official record
Conditions
Multiple Sclerosis, Relapse
Interventions
Blood samples and processing
Diagnostic Test
Lead sponsor
Regina Elena Cancer Institute
Other
Eligibility
18 Years to 60 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 20, 2020 · Synced Sep 24, 2026, 4:06 PM EDT
Completed Not applicable Interventional

Evaluation of Hemodynamic Parameters Following Transjugular Intrahepatic Portosystemic Shunt (TIPS)

NCT04050683
View directory record Official record
Conditions
Refractory Ascites
Interventions
Study - Transjugular Intrahepatic Portosystemic Shunt (TIPS), Control - Transjugular Intrahepatic Portosystemic Shunt (TIPS)
Procedure
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Dec 12, 2024 · Synced Sep 24, 2026, 4:06 PM EDT
Completed No phase listed Observational

Alterations in Cognitive Function and Cerebral Blood Flow After Conversion From Immediate Release Tacrolimus to Slow Release Envarsus

NCT03703154
View directory record Official record
Conditions
End Stage Renal Disease
Interventions
Envarsus, Tacrolimus
Drug
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years to 85 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Apr 26, 2021 · Synced Sep 24, 2026, 4:06 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Central Mechanisms of Chronic Pain and Fatigue Subtitle: Functional Imaging of Brain and Spinal Cord

NCT03075254
View directory record Official record
Conditions
Chronic Fatigue Syndrome, Fibromyalgia
Interventions
A Peltier for Sensory testing, functional magnetic resonance imaging for Brain Neuroimaging, fMRI for Spinal Cord Neuroimaging
Device
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 70 Years
Enrollment
197 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2024
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jan 26, 2025 · Synced Sep 24, 2026, 4:06 PM EDT
Terminated Not applicable Interventional Results available

Effect of Raised CBF During CEA on Cognition in DM Patients

NCT00597545
View directory record Official record
Conditions
Carotid Artery Disease, Carotid Artery Stenosis, Diabetes, Cognitive Dysfunction
Interventions
Carotid endarterectomy, Shunt
Procedure · Device
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2014
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 12, 2015 · Synced Sep 24, 2026, 4:06 PM EDT