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ClinicalTrials.gov public records Last synced Oct 2, 2026, 9:15 AM EDT

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Showing 49–72 of 109 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Breathing training with a device Clear all
Recruiting Not applicable Interventional

Inspiratory Pulmonary Rehabilitation for Children With Obesity and Asthma

NCT05608668
View directory record Official record
Conditions
Pediatric Obesity, Pediatric Asthma
Interventions
Pro2 - 60% of participant's MIP, Pro2 - 15% of participant's MIP
Device
Lead sponsor
Duke University
Other
Eligibility
8 Years to 17 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 22, 2025 · Synced Oct 2, 2026, 9:15 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Heart Rate Variability Biofeedback: It's Role in Asthma Therapeutics

NCT02766374
View directory record Official record
Conditions
Asthma
Interventions
Heart rate variability biofeedback, Placebo
Behavioral
Lead sponsor
Fred Wamboldt, MD
Other
Eligibility
18 Years to 75 Years
Enrollment
68 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2018
U.S. locations
2
States / cities
Denver, Colorado • Piscataway, New Jersey
Source: ClinicalTrials.gov public record
Updated Jan 15, 2019 · Synced Oct 2, 2026, 9:15 AM EDT
Completed Not applicable Interventional Results available

Inspiratory Muscle Training on The Severity of Exercise-Induced Bronchoconstriction and Time-Trial Performance (IMT_EIB)

NCT06336681
View directory record Official record
Conditions
Exercise Induced Bronchospasm, Exercise Induced Asthma
Interventions
PrO2Fit Device
Device
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 35 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated May 12, 2026 · Synced Oct 2, 2026, 9:15 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Home-Based Respiratory Muscle Training and Aerobic Exercise Programs to Improve Lung Health in Current and Former Cigarette Smokers

NCT07553819
View directory record Official record
Conditions
Lung Carcinoma
Interventions
Accelerometry, Aerobic Exercise, Biospecimen Collection, Educational Intervention, Electronic Health Record Review, Physical Performance Testing, Respiratory Muscle Training, Supportive Care, Survey Administration
Procedure · Other
Lead sponsor
Roswell Park Cancer Institute
Other
Eligibility
50 Years and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Aug 21, 2026 · Synced Oct 2, 2026, 9:15 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Novel Time-efficient Inspiratory Muscle Strength Training for Lowering Systolic Blood Pressure

NCT04848675
View directory record Official record
Conditions
Blood Pressure, Endothelial Dysfunction, Hypertension
Interventions
Inspiratory muscle strength training, Brisk walking
Other
Lead sponsor
University of Colorado, Boulder
Other
Eligibility
50 Years and older
Enrollment
102 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Boulder, Colorado
Source: ClinicalTrials.gov public record
Updated Nov 2, 2023 · Synced Oct 2, 2026, 9:15 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Inspiratory Muscle Strength Training in Adults With Obesity

NCT05459636
View directory record Official record
Conditions
Obesity
Interventions
High-resistance inspiratory muscle strength training, Very-low-resistance inspiratory muscle strength training
Device
Lead sponsor
Florida State University
Other
Eligibility
18 Years to 45 Years
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Aug 27, 2026 · Synced Oct 2, 2026, 9:15 AM EDT
Completed Not applicable Interventional

Enhancing Resilience in Young Stroke Survivors With Res-ET

NCT05348044
View directory record Official record
Conditions
Resilience, Stroke
Interventions
Res-ET intervention
Other
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 55 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Apr 18, 2023 · Synced Oct 2, 2026, 9:15 AM EDT
Completed Not applicable Interventional

Coherence Training for Military Personnel

NCT01599598
View directory record Official record
Conditions
Stress
Interventions
Progressive Muscle Relaxation, Coherence Advantage
Behavioral
Lead sponsor
United States Naval Medical Center, San Diego
Federal
Eligibility
Not listed
Enrollment
192 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Aug 19, 2016 · Synced Oct 2, 2026, 9:15 AM EDT
Recruiting Not applicable Interventional

Pre-operative Inspiratory Muscle Strength Training in Total Joint Surgery

NCT05381818
View directory record Official record
Conditions
Arthropathy of Knee, Arthropathy of Hip, Lower Extremity Fracture, Orthopedic Disorder
Interventions
Daily Inspiratory Muscle Training (dIMT), Acute Inspiratory Muscle Training (aIMT), Standard of Care (SOC)
Behavioral · Other
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 100 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated May 15, 2026 · Synced Oct 2, 2026, 9:15 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Mechanisms of Arterial Hypotension in Chronic Spinal Cord Injury

NCT02154412
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
Respiratory Training
Other
Lead sponsor
University of Louisville
Other
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2019
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Mar 7, 2025 · Synced Oct 2, 2026, 9:15 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Effects of Breathing Training and Nitrate on Exercise at Simulated Altitude

NCT07216755
View directory record Official record
Conditions
Healthy Adults, Mechanical Ventilation Dependence, Hypoxia, Exercise Training, Exercise Intolerance, Dietary Supplement, Nitrate Supplementation, Inspiratory Muscle Training
Interventions
Respiratory Muscle Training (RMT), Sham Respiratory Muscle Training, Dietary Supplement: Beetroot Juice Concentrate, placebo beverage
Device · Dietary Supplement
Lead sponsor
Embry-Riddle Aeronautical University
Other
Eligibility
18 Years to 40 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Daytona Beach, Florida
Source: ClinicalTrials.gov public record
Updated Oct 15, 2025 · Synced Oct 2, 2026, 9:15 AM EDT
Completed Not applicable Interventional

Programs to Support You During Chemotherapy (Pro-You)

NCT02148406
View directory record Official record
Conditions
Depressive Symptoms, Fatigue, Psychosocial Effects of Cancer and Its Treatment, Stage IIA Colon Cancer, Stage IIA Rectal Cancer, Stage IIB Colon Cancer, Stage IIB Rectal Cancer, Stage IIC Colon Cancer, Stage IIC Rectal Cancer, Stage IIIA Colon Cancer, Stage IIIA Rectal Cancer, Stage IIIB Colon Cancer, Stage IIIB Rectal Cancer, Stage IIIC Colon Cancer, Stage IIIC Rectal Cancer, Stage IVA Colon Cancer, Stage IVA Rectal Cancer, Stage IVB Colon Cancer, Stage IVB Rectal Cancer
Interventions
Yoga Skills Training (YST), questionnaire administration, fatigue and depressive symptom assessment and management, psychological stress assessment, laboratory biomarker analysis, Attention Control
Behavioral · Other
Lead sponsor
Vanderbilt-Ingram Cancer Center
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jun 23, 2015 · Synced Oct 2, 2026, 9:15 AM EDT
Recruiting Not applicable Interventional

Non-invasive Spinal Cord Stimulation and Blood Pressure Regulation After Spinal Cord Injury

NCT07504055
View directory record Official record
Conditions
Spinal Cord Injury, Orthostatic Hypertension, Autonomic Dysreflexia
Interventions
Spinal Cord Transcutaneous Stimulation
Device
Lead sponsor
University of Louisville
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
2
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Apr 28, 2026 · Synced Oct 2, 2026, 9:15 AM EDT
Not listed Not applicable Interventional

Inspiratory Muscle Training in COPD

NCT03438019
View directory record Official record
Conditions
COPD
Interventions
PrO2, Threshold Inspiratory Muscle Trainer
Device
Lead sponsor
Miami VA Healthcare System
Federal
Eligibility
40 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Jul 20, 2018 · Synced Oct 2, 2026, 9:15 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Impact of Respiratory Muscle Training and Patient Education on Chronic Constipation Outcomes

NCT05823259
View directory record Official record
Conditions
Constipation, Constipation - Functional, Dyssynergia
Interventions
Hybrid Telehealth Program: Respiratory Muscle Training and Patient Education, Standard Physical Therapy Care
Other
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Coral Gables, Florida
Source: ClinicalTrials.gov public record
Updated Dec 13, 2024 · Synced Oct 2, 2026, 9:15 AM EDT
Completed Not applicable Interventional

Investigation of the Freespira Breathing System in the Treatment of Post Traumatic Stress Disorder (PTSD)

NCT03039231
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic
Interventions
Freespira Breathing System
Device
Lead sponsor
Palo Alto Health Sciences, Inc.
Industry
Eligibility
18 Years and older
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Mar 25, 2020 · Synced Oct 2, 2026, 9:15 AM EDT
Completed Not applicable Interventional

Mechanistic Pathways of Mindfulness Meditation in Post-traumatic Stress Disorder.

NCT00778960
View directory record Official record
Conditions
Post-Traumatic Stress Disorders
Interventions
Slow Breathing, Meditation, Meditation and slow breathing, Sitting Quietly
Behavioral
Lead sponsor
Oregon Health and Science University
Other
Eligibility
25 Years to 65 Years
Enrollment
102 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Jul 13, 2015 · Synced Oct 2, 2026, 9:15 AM EDT
Completed Not applicable Interventional

Home-Based Respiratory Muscle Strength Training Program for Individuals With Post-COVID-19 Persistent Dyspnea

NCT06091280
View directory record Official record
Conditions
Post-COVID-19 Syndrome, Dyspnea
Interventions
Respiratory Muscle Strength Trainers
Device
Lead sponsor
University of South Florida
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Apr 15, 2025 · Synced Oct 2, 2026, 9:15 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Feasibility of a Mental-Health Intervention Based on Contemplative Sleep Practices

NCT07217340
View directory record Official record
Conditions
Anxiety
Interventions
Dream Yoga Inspired Intervention, Sleep Health Enhancement program
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
2
States / cities
Evanston, Illinois • Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Feb 12, 2026 · Synced Oct 2, 2026, 9:15 AM EDT
Completed Not applicable Interventional

Expiratory Muscle Conditioning in Multiple Sclerosis Using Magnetic Stimulation

NCT01758224
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
Functional Magnetic Stimulation, Resistive Expiratory Muscle Training
Other
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 70 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 4, 2016 · Synced Oct 2, 2026, 9:15 AM EDT
Completed Not applicable Interventional

FLO2 for Recovery After SCI

NCT03833674
View directory record Official record
Conditions
Spinal Cord Injury (SCI)
Interventions
Daily AIH Block, Sham dAIH Block, Respiratory Strength Training Block, AIH + Strength Training Block
Other
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 70 Years
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated May 29, 2024 · Synced Oct 2, 2026, 9:15 AM EDT
Completed Not applicable Interventional Results available

The Effects of Respiratory Training on Voice

NCT04710862
View directory record Official record
Conditions
Muscle Tension Dysphonia
Interventions
Breathing training without a device, Breathing training with a device
Behavioral
Lead sponsor
Syracuse University
Other
Eligibility
18 Years and older
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Jul 24, 2025 · Synced Oct 2, 2026, 9:15 AM EDT
Active, not recruiting Not applicable Interventional

Inspiratory Muscle Training Immediately After Lung Transplantation

NCT05309551
View directory record Official record
Conditions
Lung Transplantation, Chronic Lung Disease, Muscle Weakness, Rehabilitation
Interventions
IMT- Intervention group, IMT- Placebo group
Device
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 80 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 18, 2025 · Synced Oct 2, 2026, 9:15 AM EDT
Recruiting Not applicable Interventional

Platform of Randomized Adaptive Clinical Trials in Critical Illness

NCT05440851
View directory record Official record
Conditions
Respiratory Insufficiency, Extracorporeal Membrane Oxygenation Complication, Mechanical Ventilation Pressure High
Interventions
Ultra-Protective Ventilation Facilitated by Extracorporeal Support, Lung-Protective Ventilation (LPV), Driving Pressure-Limited Ventilation (DPL), Lung- and Diaphragm-Protective Ventilation and Sedation (LDPVS), Early Cohort corticosteroid dose, Extended Cohort corticosteroid dose, Usual care without routine corticosteroids, Usual care without extending corticosteroids, Usual care with fludrocortisone, Usual care without fludrocortisone, Drug 4 mL:, Drug 40 mg:, PEEP-20, PEEP-AOP, PEEP-10, VV ECMO-facilitated strategy of earlier awakening, extubation and rehabilitation, Electrical impedance tomography (EIT), no treatment / intervention arm is involved., Usual care, Early Routine IMT
Other · Drug
Lead sponsor
University Health Network, Toronto
Other
Eligibility
18 Years and older
Enrollment
6,250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
26
States / cities
Tucson, Arizona • Los Angeles, California • San Diego, California + 19 more
Source: ClinicalTrials.gov public record
Updated May 7, 2026 · Synced Oct 2, 2026, 9:15 AM EDT