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ClinicalTrials.gov public records Last synced Oct 4, 2026, 10:10 AM EDT

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Showing 25–48 of 101 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Brief motivational substance use intervention Clear all
Completed Not applicable Interventional

Drug Use and Sexual Risk Behaviors Among Emerging Adults in the ER

NCT03079856
View directory record Official record
Conditions
Drug Use, Sex Behavior
Interventions
Brief Intervention
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 25 Years
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Flint, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 29, 2018 · Synced Oct 4, 2026, 10:10 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Motivational Interviewing to Increase Uptake of Drug Checking and Safe Drug Use Behaviors to Reduce Overdose

NCT06855836
View directory record Official record
Conditions
Overdose
Interventions
MI-CHANCE (TS + FTIR + MI), TS + FTIR + Flu and Hepatitis A Education
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
588 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Apr 6, 2026 · Synced Oct 4, 2026, 10:10 AM EDT
Completed Not applicable Interventional

Repeated-dose Brief Intervention to Reduce Overdose and Risk Behaviors Among Naloxone Recipients

NCT02093559
View directory record Official record
Conditions
Opioid-Related Disorders, Drug Overdose
Interventions
Brief counseling Intervention
Behavioral
Lead sponsor
San Francisco Department of Public Health
Government
Eligibility
18 Years to 65 Years
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Nov 22, 2023 · Synced Oct 4, 2026, 10:10 AM EDT
Completed Not applicable Interventional

Brief Therapies for Problem Gambling Substance Abusers

NCT00685048
View directory record Official record
Conditions
Gambling
Interventions
10 minutes of psycho-education, 10 minutes of brief advice, four 50-minute individual therapy sessions of MET & CBT
Behavioral
Lead sponsor
UConn Health
Other
Eligibility
18 Years and older
Enrollment
220 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2014
U.S. locations
1
States / cities
Farmington, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 9, 2019 · Synced Oct 4, 2026, 10:10 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Substance Use Interventions for Truant Adolescents

NCT03655574
View directory record Official record
Conditions
Adolescent Problem Behavior, Truancy; Unsocialized, Marijuana Abuse, Truancy; Socialized, Substance Abuse, Alcohol Abuse
Interventions
Motivational + Family Check-up (MET+FCU), Psychoeducation
Behavioral · Other
Lead sponsor
Brown University
Other
Eligibility
12 Years to 18 Years
Enrollment
110 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
2
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jun 3, 2024 · Synced Oct 4, 2026, 10:10 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Improving Reproductive Health for Women in Opioid Medication-Assisted Treatment (OMAT)

NCT02794597
View directory record Official record
Conditions
Contraception
Interventions
SHINE intervention group
Behavioral
Lead sponsor
Denver Health and Hospital Authority
Other
Eligibility
18 Years to 44 Years · Female only
Enrollment
119 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Nov 16, 2020 · Synced Oct 4, 2026, 10:10 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Substance Use and Sexual Risk Reduction Intervention for Homeless Youth

NCT02188797
View directory record Official record
Conditions
Substance Use, Sexual Risk Behavior
Interventions
Group MI risk reduction program
Behavioral
Lead sponsor
RAND
Other
Eligibility
18 Years to 24 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
2
States / cities
Hollywood, California • Venice Beach, California
Source: ClinicalTrials.gov public record
Updated Apr 19, 2016 · Synced Oct 4, 2026, 10:10 AM EDT
Completed Not applicable Interventional Results available

Testing an Integrated Bio-Behavioral Primary HIV Prevention Intervention Among High-Risk People Who Use Drugs

NCT03282890
View directory record Official record
Conditions
Risk Behavior, HIV/AIDS, Medication Adherence, Substance Abuse
Interventions
CHRP-BB
Other
Lead sponsor
University of Connecticut
Other
Eligibility
18 Years and older
Enrollment
237 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 17, 2025 · Synced Oct 4, 2026, 10:10 AM EDT
Completed Not applicable Interventional

Family and Adolescent Motivational Incentives for Leveraging Youth

NCT01736995
View directory record Official record
Conditions
Substance-Related Disorders
Interventions
Functional Family Therapy, Motivational Enhancement Tx/Cognitive Behavioral Tx, Contingency Management
Behavioral
Lead sponsor
Oregon Research Institute
Other
Eligibility
13 Years to 17 Years
Enrollment
212 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2018
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated May 2, 2018 · Synced Oct 4, 2026, 10:10 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Home Visitation Enhancing Linkages Project

NCT03750487
View directory record Official record
Conditions
Substance Use
Interventions
e-screening & brief intervention (e-SBI), Control e-SBI
Behavioral
Lead sponsor
The National Center on Addiction and Substance Abuse at Columbia University
Other
Eligibility
18 Years and older · Female only
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 7, 2024 · Synced Oct 4, 2026, 10:10 AM EDT
Completed Not applicable Interventional Results available

Telehealth-Clinical Advocacy Project

NCT04911426
View directory record Official record
Conditions
Substance Use
Interventions
Telehealth
Behavioral
Lead sponsor
Texas Christian University
Other
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Waukegan, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 18, 2025 · Synced Oct 4, 2026, 10:10 AM EDT
Recruiting Not applicable Interventional

Evaluating Caregiver Involvement in Primary Care-Based Brief Interventions for Adolescent Alcohol Use Problems

NCT06593652
View directory record Official record
Conditions
Alcohol Use, Adolescent, Mild Alcohol Use Disorder, Mild Substance Use Disorder
Interventions
Teen Intervene - Adolescent Only, Teen Intervene with Caregiver Session, Family Check Up
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
12 Years to 17 Years
Enrollment
615 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Jan 2, 2026 · Synced Oct 4, 2026, 10:10 AM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers Results available

Brief Intervention in At-Risk First-time Mothers

NCT00230009
View directory record Official record
Conditions
Substance Use
Interventions
Brief motivational intervention
Behavioral
Lead sponsor
Wayne State University
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2007
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 8, 2013 · Synced Oct 4, 2026, 10:10 AM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

Brief Substance Use Intervention for Youth in Teen Court

NCT01464554
View directory record Official record
Conditions
Alcohol or Other Drugs Use
Interventions
Usual care, Project Free Talk
Behavioral
Lead sponsor
RAND
Other
Eligibility
14 Years to 18 Years
Enrollment
193 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2014
U.S. locations
1
States / cities
Santa Barbara, California
Source: ClinicalTrials.gov public record
Updated May 8, 2015 · Synced Oct 4, 2026, 10:10 AM EDT
Completed Not applicable Interventional

Primary Care-Based Interventions to Reduce Alcohol Use Among HIV Patients

NCT01671501
View directory record Official record
Conditions
HIV, Acquired Immunodeficiency Syndrome, Alcoholism, Alcoholic Intoxication, Substance-Related Disorders
Interventions
Motivational Interviewing, Email Feedback, Usual Care
Behavioral · Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 100 Years
Enrollment
614 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Oct 10, 2018 · Synced Oct 4, 2026, 10:10 AM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

Computer-based Brief Intervention for Perinatal Substance Abuse

NCT00685074
View directory record Official record
Conditions
Substance Abuse
Interventions
Computer-based Motivational Interviewing, Time control
Behavioral
Lead sponsor
Wayne State University
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
143 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2011
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 14, 2011 · Synced Oct 4, 2026, 10:10 AM EDT
Completed Not applicable Interventional

Project Health Link: Connecting Patients With Services

NCT00251173
View directory record Official record
Conditions
Drug Abuse
Interventions
Strengths Based Case Management (SBCM), Motivational Enhancement Therapy (MET), Brief Informational Feedback (BIF) session
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
19 Years to 60 Years
Enrollment
755 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
1
States / cities
Flint, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 8, 2016 · Synced Oct 4, 2026, 10:10 AM EDT
Completed Not applicable Interventional

Screening, Brief Intervention and Referral to Treatment for Substance Abuse in Mental Health Treatment Settings

NCT01883791
View directory record Official record
Conditions
Substance Use Disorders, Mental Illness
Interventions
SBIRT, Health Education
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older
Enrollment
1,080 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
2
States / cities
Los Angeles, California • Oxnard, California
Source: ClinicalTrials.gov public record
Updated Nov 2, 2018 · Synced Oct 4, 2026, 10:10 AM EDT
Withdrawn Not applicable Interventional

Reducing Problematic Substance Use in Youth With Chronic Medical Conditions

NCT01709201
View directory record Official record
Conditions
Alcohol Abuse, Drug Abuse
Interventions
Brief Intervention
Behavioral
Lead sponsor
Boston Children's Hospital
Other
Eligibility
14 Years to 18 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 21, 2017 · Synced Oct 4, 2026, 10:10 AM EDT
Completed Not applicable Interventional

Preventing Premature Death in Patients With Serious Opioid-related Infection

NCT03999450
View directory record Official record
Conditions
Opioid Use
Interventions
brief motivational intervention (BMI), cognitive behavioral therapy
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Jul 28, 2020 · Synced Oct 4, 2026, 10:10 AM EDT
Not yet recruiting Not applicable Interventional

Substance Use in Assault-Injured Young Adults

NCT07070414
View directory record Official record
Conditions
Alcohol Misuse, Cannabis Misuse
Interventions
Brief Negotiation Interview intervention (BNI) (adapted)
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 25 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2028
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jun 4, 2026 · Synced Oct 4, 2026, 10:10 AM EDT
Completed Not applicable Interventional Results available

Effectiveness of an Evidence-based Stepped Care System for Alcohol and Other Drug Use Problems Among Congolese Refugees in Zambia

NCT05471921
View directory record Official record
Conditions
Alcohol and Substance-Related Mental Disorders
Interventions
SBIRT, Treatment as usual
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
15 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 19, 2026 · Synced Oct 4, 2026, 10:10 AM EDT
Withdrawn Phase 3 Interventional Accepts healthy volunteers

Advancing Adolescent Screening and Brief Intervention Protocols in Primary Care Settings

NCT01523444
View directory record Official record
Conditions
Substance Abuse
Interventions
computer-assisted Screening & Brief Advice, computer-assisted Screening & Brief Advice Plus
Behavioral
Lead sponsor
Treatment Research Institute
Other
Eligibility
12 Years to 18 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 28, 2023 · Synced Oct 4, 2026, 10:10 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

An Innovative HIV Prevention Intervention Using Social Networking Technology

NCT01381653
View directory record Official record
Conditions
Sexual Risk, Substance Use
Interventions
Behavioral: HIV prevention intervention
Other
Lead sponsor
Hunter College of City University of New York
Other
Eligibility
18 Years to 29 Years · Male only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 3, 2013 · Synced Oct 4, 2026, 10:10 AM EDT