Search | Clinical Trials Finder

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Nov 5, 2026, 10:56 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 769–792 of 975 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Bupivacaine Clear all

Conditions: Postoperative Pain
Interventions: Lumbar Plexus Blockade, Control; Procedure
Lead sponsor: Hospital for Special Surgery, New York; Other
Eligibility: 18 Years to 65 Years
Enrollment: 83 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2011
U.S. locations: 2
States / cities: New York, New York

Conditions: Femoral Fractures
Interventions: Liposomal Bupivacaine, Ropivacaine HCL; Drug
Lead sponsor: Ian Elliott Brown; Other
Eligibility: 18 Years to 70 Years
Enrollment: 3 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Sacramento, California

Conditions: Inguinal Hernia, Anesthesia, Local
Interventions: Open Inguinal Hernia Repair - Local Anesthesia, Inguinal Hernia Repair - General Anesthesia; Other
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 60 Years and older
Enrollment: 18 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2027
U.S. locations: 3
States / cities: Dallas, Texas • Houston, Texas • Madison, Wisconsin

Conditions: Osteoarthritis, Hip
Interventions: isobaric bupivacaine, hyperbaric bupivacaine, isobaric mepivacaine; Drug
Lead sponsor: Thomas Jefferson University; Other
Eligibility: 18 Years to 84 Years
Enrollment: 159 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019
U.S. locations: 2
States / cities: Bensalem, Pennsylvania • Philadelphia, Pennsylvania

Conditions: Pain Management, Sternotomy
Interventions: Exparel, Bupivacaine; Drug
Lead sponsor: University of Kansas Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2023
U.S. locations: 1
States / cities: Kansas City, Kansas

Conditions: Total Shoulder Arthroplasty
Interventions: bupivacaine., Saline; Drug
Lead sponsor: University of Minnesota; Other
Eligibility: 18 Years to 85 Years
Enrollment: 110 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Maternal Anaesthesia and Analgesia Affecting Fetus or Newborn, Breast Feeding, Fentanyl, Bupivacaine, Nalbuphine
Interventions: Not listed
Lead sponsor: University Hospitals Cleveland Medical Center; Other
Eligibility: 18 Years and older · Female only
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Total Ankle Arthroplasty, Postsurgical Analgesia
Interventions: EXPAREL, 0.25% bupivacaine (HCl): 50 ml, 0.25% bupivacaine (HCl): 30 ml; Drug
Lead sponsor: Emory University; Other
Eligibility: 18 Years and older
Enrollment: 104 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2029
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Arthroplasty, Replacement, Knee, Nerve Block
Interventions: Adductor Canal Nerve Block Catheter, Adductor Canal Nerve Block Sham Catheter, Bupivacaine; Device · Drug
Lead sponsor: University of Chicago; Other
Eligibility: Up to 85 Years
Enrollment: 165 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2017
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Malignant Neoplasms of Female Genital Organs, Gynecologic Cancer
Interventions: Bupivacaine, Liposomal Bupivacaine, Oxycodone, Pill Diary, Symptom Questionnaire; Drug · Behavioral
Lead sponsor: M.D. Anderson Cancer Center; Other
Eligibility: 18 Years and older · Female only
Enrollment: 105 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2020
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Inguinal Hernia
Interventions: Regional Anesthesia, General Anesthesia; Drug
Lead sponsor: Boston Children's Hospital; Other
Eligibility: Up to 60 Weeks
Enrollment: 643 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2018
U.S. locations: 10
States / cities: Aurora, Colorado • Chicago, Illinois • Iowa City, Iowa + 7 more

Conditions: Pain, Postoperative, Pharmacokinetics
Interventions: Exparel, Bupivacaine; Drug
Lead sponsor: Milton S. Hershey Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2026
U.S. locations: 1
States / cities: Hershey, Pennsylvania

Conditions: Knee Arthroplasty, Total
Interventions: Liposomal Bupivacaine, Bupivacaine, Clonidine, Epinephrine, Buprenorphine and Dexamethasone (BPV-CEBD) Combination; Drug
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 18 Years and older
Enrollment: 90 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2027
U.S. locations: 1
States / cities: Winston-Salem, North Carolina

Conditions: Pain
Interventions: Intrathecal morphine injection, EXPAREL; Drug
Lead sponsor: Pacira Pharmaceuticals, Inc; Industry
Eligibility: 18 Years and older · Female only
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015
U.S. locations: 5
States / cities: Port Saint Lucie, Florida • Minneapolis, Minnesota • New Brunswick, New Jersey + 2 more

Conditions: Knee Osteoarthritis
Interventions: Duloxetine, Intra-Articular Injection, Nerve Procedure with long acting blocks, Nerve Procedure with nerve ablation, Pain Coping Skills Training, Best Practices; Drug · Combination Product · Procedure + 2 more
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years and older
Enrollment: 1,937 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2025
U.S. locations: 24
States / cities: Sacramento, California • San Diego, California • Aurora, Colorado + 19 more

Conditions: Thyroid, Parathyroid Adenoma
Interventions: Lidocaine Epinephrine, Bupivacaine Hydrochloride-EPINEPHrine, Lidocaine Epinephrine, Bupivacaine Hydrochloride-EPINEPHrine; Drug
Lead sponsor: University of Missouri-Columbia; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2025
U.S. locations: 1
States / cities: Columbia, Missouri

Conditions: Post-operative Pain, Total Shoulder Arthroplasty, Osteoarthritis of the Shoulder, Pain Management
Interventions: Liposomal Bupivicaine 1.3%, Bupivacaine 0.5%; Drug
Lead sponsor: Hartford Hospital; Other
Eligibility: 18 Years to 100 Years
Enrollment: 90 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: Hartford, Connecticut

Conditions: Low Back Pain
Interventions: Radiofrequency denervation of medial branches, 0.5% bupivacaine, 2% lidocaine, Radiofrequency denervation; Procedure · Drug
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years and older
Enrollment: 151 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2009
U.S. locations: 2
States / cities: Washington D.C., District of Columbia • Baltimore, Maryland

Conditions: Pain, Postoperative, Major Abdominal Surgery
Interventions: TAP block, Epidural analgesia, EXPAREL, Bupivacaine; Procedure · Drug
Lead sponsor: The Cleveland Clinic; Other
Eligibility: 18 Years to 85 Years
Enrollment: 514 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2019
U.S. locations: 2
States / cities: Cleveland, Ohio

Conditions: Pain, Postoperative
Interventions: Liposomal Injection Bupivacaine (Exparel), Standard bupivicaine; Drug
Lead sponsor: Emory University; Other
Eligibility: 18 Years and older
Enrollment: 4 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2014
U.S. locations: 3
States / cities: Atlanta, Georgia

Conditions: Rhytidoplasty
Interventions: clonidine, glycopyrrolate, propofol, ketamine, marcaine, scopolamine, midazolam, ondansetron, metoclopramide, lidocaine, famotidine, desflurane, sevoflurane; Drug · Device
Lead sponsor: Mercy Facial Plastic Surgery Center; Other
Eligibility: 18 Years and older · Female only
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2014
U.S. locations: 1
States / cities: Springfield, Missouri

Conditions: Acute Pain
Interventions: Drug: Bupivacaine 0.375% 20 mL, Drug: Bupivacaine 0.375% diluted to 0.1875%; Drug
Lead sponsor: Anna Uskova; Other
Eligibility: 18 Years to 90 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 2
States / cities: Pittsburgh, Pennsylvania

Conditions: Bunion, Hallux Rigidus
Interventions: 0.5% ropivacaine, Exparel; Drug
Lead sponsor: OhioHealth; Other
Eligibility: 18 Years and older
Enrollment: 2 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2016
U.S. locations: 2
States / cities: Columbus, Ohio • Westerville, Ohio

Conditions: Postsurgical Pain, Analgesia, Prostatectomy
Interventions: EXPAREL 20 mL, EXPAREL 40 mL; Drug
Lead sponsor: Pacira Pharmaceuticals, Inc; Industry
Eligibility: 18 Years to 75 Years · Male only
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012
U.S. locations: 1
States / cities: Brighton, Massachusetts

Search by objective public record fields.

Lumbar Plexus Block for Postoperative Pain Control After Hip Arthroscopy. A Randomized Controlled Trial

Effects of Liposomal Bupivacaine for Acute Pain in Hip and Femur Fractures

A Pilot Study of Local Anesthesia for Inguinal Hernia Surgery in Older Adults

3 Local Anesthetics for Spinal Anesthesia in Primary Total Hip Arthroplasty

Liposomal Bupivacaine vs Bupivacaine for Pain Control After Sternotomy

Addition of a Pectoserratus Block to Interscalene Block in Patients Undergoing Total Shoulder Replacement

Intrapartum Epidural Fentanyl and Breast-feeding in the Immediate Postpartum Period: a Prospective Cohort Study

Efficacy of EXPAREL vs. Bupivacaine

Epidural Catheter With or Without Adductor Canal Nerve Block for Postoperative Analgesia Following Total Knee Arthroplasty

Wound Infiltration With Liposomal Bupivacaine vs. Standard Wound Infiltration With Bupivacaine in Patient's Undergoing Open Gynecologic Surgery on an Enhanced Recovery Pathway

A Multi-site Randomized Controlled Trial Comparing Regional and General Anesthesia for Effects on Neurodevelopmental Outcome and Apnea in Infants

Liposomal Bupivacaine Versus Plain Bupivacaine After Intercostal Injections For Pain Management After Thoracoscopy

Liposomal Bupivacaine vs Perineural Adjuvants in Adductor Canalf and iPACK Blocks in Total Knee Arthroplasty

Evaluation of the Safety and Efficacy of EXPAREL When Administered Into the TAP in Subjects Undergoing Cesarean Section

A Sequenced Strategy for Improving Outcomes in People With Knee Osteoarthritis Pain

Exparel Injection Effect on Postoperative Opioid Usage

LIBERATE - LIposomal Bupivacaine vERsus Adjuncts in Total shouldErs

Efficacy and Cost: Benefit Ratio of 0, 1, and 2 Medial Branch Blocks for Lumbar Facet Joint Radiofrequency Denervation

Bilateral Transversus Abdominis Plane Block With Exparel Verus Continuous Epidural Analgesia With Bupivacaine

Exparel vs. Standard Bupivicaine for Abdominoplasty

Anesthetics in Rhytidoplasty - A Comparison Study

Volume Versus Concentration: Clinical Effectiveness of Single Shot Quadrates Lumborum Block Using Either a High Volume/Low Concentration or Low Volume/High Concentration Injectate for Total Hip Arthroplasty.

Pericapsular Exparel for Pain Relief in Bunionectomy and Related Procedures

TAP-patients With Robotic Assisted Lap Prostatectomy