- Conditions
- Post-Traumatic Stress Disorders, Opiate Use Disorder
- Interventions
- Buprenorphine, Cognitive Processing Therapy (CPT), Individual Drug Counseling (IDC)
- Drug · Behavioral
- Lead sponsor
- VA Office of Research and Development
- Federal
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 38 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2023
- U.S. locations
- 2
- States / cities
- West Haven, Connecticut • Bedford, Massachusetts
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Showing 1–24
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- Conditions
- Opioid-Related Disorders, Drug Addiction, Pregnancy Related, Substance Abuse, Drug Abuse, Neonatal Abstinence Syndrome, Neonatal Opiate Withdrawal Syndrome, Drug Abuse in Pregnancy
- Interventions
- Buprenorphine Injection, Buprenorphine Sublingual Product
- Drug
- Lead sponsor
- T. John Winhusen, PhD
- Other
- Eligibility
- Not listed
- Enrollment
- 71 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2024
- U.S. locations
- 10
- States / cities
- Jacksonville, Florida • Boston, Massachusetts • Portland, Oregon + 6 more
- Conditions
- Opioid-use Disorder
- Interventions
- OXD01 digital therapy, Standard of Care
- Device · Other
- Lead sponsor
- Orexo AB
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 437 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2023
- U.S. locations
- 21
- States / cities
- Birmingham, Alabama • Oceanside, California • San Diego, California + 17 more
- Conditions
- Chronic Pain
- Interventions
- VCPM
- Other
- Lead sponsor
- VA Office of Research and Development
- Federal
- Eligibility
- 18 Years and older
- Enrollment
- 44 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2021
- U.S. locations
- 2
- States / cities
- Aurora, Colorado • West Haven, Connecticut
- Conditions
- Hepatitis C, Heroin Dependence
- Interventions
- Buprenorphine/naloxone, pegInterferon
- Drug
- Lead sponsor
- National Institute on Drug Abuse (NIDA)
- NIH
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 10 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2003 – 2006
- U.S. locations
- 1
- States / cities
- Oakland, California
- Conditions
- Methamphetamine-dependence
- Interventions
- Buprenorphine injection (BUP-Inj), Placebo injection
- Drug · Other
- Lead sponsor
- Madhukar H. Trivedi, MD
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 18 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023
- U.S. locations
- 6
- States / cities
- Los Angeles, California • Oakland, California • Tulsa, Oklahoma + 3 more
- Conditions
- Opioid Dependence
- Interventions
- Memantine, Placebo
- Drug
- Lead sponsor
- University of Massachusetts, Worcester
- Other
- Eligibility
- 18 Years to 25 Years
- Enrollment
- 87 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2013
- U.S. locations
- 1
- States / cities
- Worcester, Massachusetts
- Conditions
- Opioid Withdrawal, Chronic Pain
- Interventions
- Buprenorphine Patch, Placebo, Transcranial Magnetic Stimulation (TMS), Sham Transcranial Magnetic Stimulation (TMS)
- Drug · Device
- Lead sponsor
- Medical University of South Carolina
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 240 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2024 – 2029
- U.S. locations
- 1
- States / cities
- Charleston, South Carolina
- Conditions
- Opioid-use Disorder
- Interventions
- Patient Navigation, Buprenorphine
- Behavioral · Drug
- Lead sponsor
- Friends Research Institute, Inc.
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 373 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2026
- U.S. locations
- 2
- States / cities
- Baltimore, Maryland
- Conditions
- Cocaine Use Disorder
- Interventions
- Extended-Release Naltrexone, Extended Release Buprenorphine, Placebo (PLB) Injectable matched to XR-NTX, Placebo (PLB) Injectable matched to XR-BUP
- Drug
- Lead sponsor
- University of Texas Southwestern Medical Center
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 427 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2025
- U.S. locations
- 12
- States / cities
- Birmingham, Alabama • Little Rock, Arkansas • Los Angeles, California + 8 more
- Conditions
- Opioid Dependence
- Interventions
- buprenorphine/naloxone combination
- Drug
- Lead sponsor
- New York State Psychiatric Institute
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 51 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2005 – 2011
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Opiate-related Disorders
- Interventions
- Buprenorphine/naloxone, Methadone
- Drug
- Lead sponsor
- University of California, Los Angeles
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 1,269 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2010
- U.S. locations
- 9
- States / cities
- Los Angeles, California • Sacramento, California • San Francisco, California + 6 more
- Conditions
- Opioid-Related Disorders, Substance-Related Disorders, Narcotic-Related Disorders
- Interventions
- Injectable extended-release buprenorphine, Sublingual buprenorphine-naloxone
- Drug
- Lead sponsor
- Yih-Ing Hser
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 140 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2026
- U.S. locations
- 7
- States / cities
- El Dorado, Arkansas • Garberville, California • Gibson City, Illinois + 4 more
- Conditions
- HIV Infection, HIV Infections
- Interventions
- Raltegravir
- Drug
- Lead sponsor
- Yale University
- Other
- Eligibility
- 21 Years to 60 Years
- Enrollment
- 12 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2009
- U.S. locations
- 1
- States / cities
- New Haven, Connecticut
- Conditions
- Opioid Use Disorder, Chronic Pain
- Interventions
- Patient-Oriented Dosing (POD), Pain Self-Management (PSM), Usual Care, Standard Buprenorphine Dosing Condition
- Drug · Behavioral
- Lead sponsor
- Erin Winstanley
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 273 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2026
- U.S. locations
- 13
- States / cities
- Baltimore, Maryland • Dundalk, Maryland • Hagerstown, Maryland + 6 more
- Conditions
- Opioid-use Disorder
- Interventions
- Contingency management
- Behavioral
- Lead sponsor
- Rowan University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 92 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2020 – 2024
- U.S. locations
- 1
- States / cities
- Camden, New Jersey
- Conditions
- Opioid-use Disorder
- Interventions
- CAM2038, Buprenorphine Sublingual Product
- Drug
- Lead sponsor
- Yale University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 2,000 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2024
- U.S. locations
- 35
- States / cities
- Oakland, California • San Leandro, California • New Haven, Connecticut + 25 more
- Conditions
- Major Depressive Disorder
- Interventions
- ALKS 5461, Placebo
- Drug
- Lead sponsor
- Alkermes, Inc.
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 32 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011
- U.S. locations
- 2
- States / cities
- St. Petersburg, Florida • Atlanta, Georgia
- Conditions
- Opioid Use Disorder
- Interventions
- Naltrexone, Placebo, Buprenorphine
- Drug
- Lead sponsor
- Alkermes, Inc.
- Industry
- Eligibility
- 18 Years to 60 Years
- Enrollment
- 101 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2017
- U.S. locations
- 9
- States / cities
- Lauderhill, Florida • Oakland Park, Florida • Winfield, Illinois + 6 more
- Conditions
- Opioid Use Disorder
- Interventions
- High Dose Buprenorphine, Standard Buprenorphine Dose
- Drug
- Lead sponsor
- Rutgers, The State University of New Jersey
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 140 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2026
- U.S. locations
- 1
- States / cities
- Newark, New Jersey
- Conditions
- Postoperative Pain
- Interventions
- Dexamethasone, Buprenorphine
- Drug
- Lead sponsor
- Hospital for Special Surgery, New York
- Other
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 90 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2014
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Opioid Use Disorder, Healthy
- Interventions
- Magnetic Resonance Imaging (MRI), Computer Tasks
- Other · Behavioral
- Lead sponsor
- University of Michigan
- Other
- Eligibility
- 18 Years to 55 Years
- Enrollment
- 185 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2025 – 2028
- U.S. locations
- 1
- States / cities
- Ann Arbor, Michigan
- Conditions
- Opioid-Related Disorders, Heroin Dependence
- Interventions
- Buprenorphine
- Drug
- Lead sponsor
- New York State Psychiatric Institute
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2010
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Opioid Use Disorder (OUD)
- Interventions
- SL-BUP, XR-BUP, XR-NTX, MM, MMR, MMD
- Drug · Behavioral
- Lead sponsor
- NYU Langone Health
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 1,516 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2027
- U.S. locations
- 21
- States / cities
- Little Rock, Arkansas • Tarzana, California • Bridgeport, Connecticut + 17 more