Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 15, 2026, 3:41 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 289–312 of 355 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Care pathway Clear all

Conditions: Knee Osteoarthritis, Knee Arthropathy, Surgery
Interventions: Personalized outcome prediction tool + targeted interventions, Standard of Care TKA; Behavioral
Lead sponsor: The Cleveland Clinic; Other
Eligibility: 18 Years to 80 Years
Enrollment: 300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Diet, Healthy, Food, Nutrition, Intensive Care, Abdominal Trauma, Surgery, Intra-abdominal Infection, Sepsis, Ischemic Bowel, Vascular, Penetrating Abdominal Trauma, Enteral Feeding, Oral
Interventions: Nutrition Ecosystem pathway, Comparator; Combination Product · Other
Lead sponsor: Duke University; Other
Eligibility: 18 Years and older
Enrollment: 300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2027
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Diffuse Intrinsic Pontine Glioma, Diffuse Midline Glioma, H3 K27M-Mutant, Recurrent Diffuse Intrinsic Pontine Glioma, Recurrent Diffuse Midline Glioma, H3 K27M-Mutant, Recurrent WHO Grade III Glioma, WHO Grade III Glioma
Interventions: ONC201, Radiation Therapy, Paxalisib, DNX-2401; Drug · Radiation
Lead sponsor: University of California, San Francisco; Other
Eligibility: 2 Years to 39 Years
Enrollment: 360 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2029
U.S. locations: 19
States / cities: Birmingham, Alabama • Los Angeles, California • San Diego, California + 16 more

Conditions: Post Traumatic Stress Disorder
Interventions: CPT Skills, Cognitive Processing Therapy, Present Centered Therapy, Shared Decision Making, Measurement Based Care; Behavioral
Lead sponsor: United States Department of Defense; Federal
Eligibility: 18 Years and older
Enrollment: 280 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 4
States / cities: Phoenix, Arizona • New Orleans, Louisiana • Charleston, South Carolina + 1 more

Conditions: Autism, Neurodevelopment
Interventions: Automated AAC Assessment and Low-Tech AAC Implementation Support, Standard AAC Support; Behavioral
Lead sponsor: Indiana University; Other
Eligibility: 3 Years to 14 Years
Enrollment: 500 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2027 – 2032
U.S. locations: 1
States / cities: Charlottesville, Virginia

Conditions: Lung Neoplasms, Carcinoma Non-small-cell Lung, Adenocarcinoma
Interventions: Multifocal Lung Adenocarcinoma; Genetic
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2025
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Abdominal Trauma
Interventions: Nutrition Supplement; Dietary Supplement
Lead sponsor: Duke University; Other
Eligibility: 15 Years and older
Enrollment: 150 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Stomach Cancer, Esophageal Cancer, Bladder Cancer, Skin Cancer, Lung Cancer, Uterine Cancer, Ovarian Cancer
Interventions: standard of care; Other
Lead sponsor: New Mexico Cancer Research Alliance; Other
Eligibility: 18 Years and older
Enrollment: 13 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2011
U.S. locations: 1
States / cities: Albuquerque, New Mexico

Conditions: Cognitive Impairment, Emergency Care, Dementia, Delirium
Interventions: PD4ED 3-step intervention (ED assessment, outpatient assessment, Brain health plan); Diagnostic Test
Lead sponsor: Yale University; Other
Eligibility: 65 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 2
States / cities: New Haven, Connecticut • Chicago, Illinois

Conditions: Stage IIA Breast Cancer AJCC v6 and v7, Stage IIB Breast Cancer AJCC v6 and v7, Stage IIIA Breast Cancer AJCC v7, Stage IIIB Breast Cancer AJCC v7, Stage IIIC Breast Cancer AJCC v7, Triple-Negative Breast Carcinoma
Interventions: Carboplatin, Gamma-Secretase Inhibitor RO4929097, Laboratory Biomarker Analysis, Paclitaxel, Pharmacological Study, Therapeutic Conventional Surgery; Drug · Other · Procedure
Lead sponsor: National Cancer Institute (NCI); NIH
Eligibility: 18 Years and older
Enrollment: 14 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2015
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Testicular Cancer
Interventions: Goal-focused Emotion-regulation Therapy; Behavioral
Lead sponsor: University of California, Irvine; Other
Eligibility: 18 Years to 39 Years · Male only
Enrollment: 35 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2023
U.S. locations: 1
States / cities: Irvine, California

Conditions: Lower Extremity Amputation
Interventions: Lower Extremity Amputation Pathway; Other
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years and older
Enrollment: 11 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Fresno, California

Conditions: Acute Coronary Syndrome, Chest Pain
Interventions: Blood Sample, HEART Score; Procedure · Behavioral
Lead sponsor: University of Florida; Other
Eligibility: 21 Years and older
Enrollment: 1,572 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2020
U.S. locations: 6
States / cities: Sacramento, California • Gainesville, Florida • Baltimore, Maryland + 3 more

Conditions: Decision Support System, Outcome
Interventions: Routine care, AFM; Procedure · Device
Lead sponsor: Assistance Publique - Hôpitaux de Paris; Other
Eligibility: 18 Years and older
Enrollment: 2,007 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 2
States / cities: Irvine, California • Los Angeles, California

Conditions: Posterior Spine Surgery
Interventions: Spine surgery analgesic pathway, Usual Care; Other
Lead sponsor: The Cleveland Clinic; Other
Eligibility: 18 Years to 80 Years
Enrollment: 299 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2019
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Osteoarthritis
Interventions: Osteoarthritis Physical Activity Care Pathway; Behavioral
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 65 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: Stage 2 Cardiovascular-Kidney-Metabolic Syndrome, Cardiovascular Disease Other
Interventions: Dietary changes via Instacart vouchers, Dietary changes via access to Mid-Ohio Farmacy, Behavior changes via access to Health Impact Ohio Hub, Behavioral nutrition counseling, Cooking classes, Dietary changes to Delivery fees; Other
Lead sponsor: Ohio State University; Other
Eligibility: 18 Years and older
Enrollment: 106 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Diabetes Mellitus, Type 2, Cardiovascular Diseases
Interventions: Intense Education Intervention; Other
Lead sponsor: Duke University; Other
Eligibility: 18 Years and older
Enrollment: 1,049 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2022
U.S. locations: 44
States / cities: Birmingham, Alabama • Mobile, Alabama • Anchorage, Alaska + 41 more

Conditions: Knee Replacement, Total
Interventions: TKA Journey - patient education, Optimized Rehab Scheduling, Usual Rehab, Physical Therapist reminders; Behavioral · Other
Lead sponsor: University of Pittsburgh; Other
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Pain, Postoperative
Interventions: Liposomal Bupivacaine, 0.25% Bupivacaine with epinephrine, Saline; Drug
Lead sponsor: American Hip Institute; Other
Eligibility: 18 Years to 90 Years
Enrollment: 107 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 2
States / cities: Hinsdale, Illinois • Westmont, Illinois

Conditions: Sleep Apnea, Obstructive
Interventions: Reach for Equity in Pediatric Obstructive Sleep Evaluation (REPOSE), Usual Care; Other
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 2 Years to 12 Years
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Sepsis
Interventions: PRESS Intervention; Behavioral
Lead sponsor: Emory University; Other
Eligibility: 18 Years and older
Enrollment: 984 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 3
States / cities: Atlanta, Georgia • Iowa City, Iowa • St Louis, Missouri

Conditions: Pregnancy Related, Opioid Use Disorder
Interventions: CADENCE program; Other
Lead sponsor: University of South Florida; Other
Eligibility: 18 Years and older · Female only
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: Tampa, Florida

Conditions: Head and Neck Carcinoma
Interventions: Best Practice, Discussion, Financial Navigation, Survey Administration; Other
Lead sponsor: Roswell Park Cancer Institute; Other
Eligibility: 18 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Buffalo, New York

Search by objective public record fields.

Improving Total Knee Arthroplasty Dissatisfaction Through a Personalized Approach Focusing on PROMs Phenotypes

The PASTDUe Nutrition Ecosystem Project (PASTDUe)

Combination Therapy for the Treatment of Diffuse Midline Gliomas

Reducing Dropout and Improving Outcomes From PTSD Therapy: When to Switch Therapies or Stay the Course

Reciprocal Innovation to Optimize Low-Tech Augmentative and Alternative Communication (AAC) for Individuals

Treatment of Multifocal Lung Adenocarcinoma

Personalized Nutrition to Improve Recovery in Trauma

Comparison of Standard of Care or Treatment on Protocol

Pathway to Detection & Differentiation of Delirium & Dementia in the Emergency Department

Gamma-Secretase/Notch Signalling Pathway Inhibitor RO4929097, Paclitaxel, and Carboplatin Before Surgery in Treating Patients With Stage II or Stage III Triple-Negative Breast Cancer

Young Adult Latino Testicular Cancer Survivors: a Pilot Study of Goal-Focused Emotion Regulation Therapy (GET)

Impact of a Lower Extremity Amputation Pathway Protocol in Dysvascular Patients

High-Sensitivity Cardiac Troponin T to OPtimize Chest Pain Risk Stratification

Assisted Fluid Management (AFM) System and Postoperative Outcome After High-risk Abdominal Surgery

Evaluation of Spine Surgery Analgesic Pathway

Physical Activity Pathway for Patients With Osteoarthritis in Primary Care (OA-PCP)

SUSTAIN: Behavior Change and Nutrition Security for CKMS

A 12 Month Site Randomized Trial in Adults With Type 2 Diabetes Mellitus and History of Cardiovascular Disease

Knee Replacement Rehabilitation Care Pathways

Intraoperative Liposomal Bupivacaine vs. Bupivacaine for Total Hip Replacement Pain Management

The REPOSE (Reach for Equity in Pediatric Sleep Evaluation) Navigation Intervention

Impact of a Prehospital Sepsis Protocol on Timely Antibiotic Administration and Subsequent Adverse Events

Continuous And Data-drivEN CarE (CADENCE) Pilot

A Financial Intervention (Financial Compass) to Identify and Address Financial Hardship Among Head and Neck Cancer Patients, Financial Compass Trial