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ClinicalTrials.gov public records Last synced Oct 17, 2026, 8:53 PM EDT

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Showing 1–24 of 53 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Centralized Intervention Clear all
Completed Phase 4 Interventional

Hyperpolarized Imaging for New Treatments

NCT04259970
View directory record Official record
Conditions
Cystic Fibrosis
Interventions
Initiation of CFTR Modulator
Drug
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
6 Years to 18 Years
Enrollment
47 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
3
States / cities
Cincinnati, Ohio • Charlottesville, Virginia • Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Oct 7, 2026 · Synced Oct 17, 2026, 8:53 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Transforming Opioid Prescribing in Primary Care

NCT01909076
View directory record Official record
Conditions
Chronic Pain, Opioid-Related Disorders
Interventions
Electronic decision support tools, Enhanced patient education materials, Nurse care management, Electronic Patient Registry, Academic detailing
Behavioral
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years and older
Enrollment
53 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 3, 2016 · Synced Oct 17, 2026, 8:53 PM EDT
Not yet recruiting Not applicable Interventional

Pharmacist-Assisted Titration of Rx to Implement Optimal Medical Therapy for Heart Failure

NCT07714239
View directory record Official record
Conditions
Heart Failure, Heart Failure, Systolic
Interventions
Pharmacist/Cardiologist Virtual Team Digital Consultation
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
585 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Sep 17, 2026 · Synced Oct 17, 2026, 8:53 PM EDT
Not listed Not applicable Interventional

Prevent Maternal Mortality Using Mobile Technology

NCT05339867
View directory record Official record
Conditions
Post-Partum
Interventions
Prevent Maternal Mortality using Mobile technology (PM3)
Behavioral
Lead sponsor
Emory University
Other
Eligibility
18 Years to 45 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
2
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Apr 21, 2022 · Synced Oct 17, 2026, 8:53 PM EDT
Recruiting Not applicable Interventional

Lifestyle Intervention for Veterans With Blood Cancer: Tele-Intervention

NCT07058571
View directory record Official record
Conditions
Blood Cancers
Interventions
EXERCISE TRAINING WITH OR WITHOUT MEDICATION
Other
Lead sponsor
VA Pittsburgh Healthcare System
Federal
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2026
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 10, 2025 · Synced Oct 17, 2026, 8:53 PM EDT
Completed Not applicable Interventional

Pragmatic Collaborative Care for Cardiac Inpatients With Depression or Anxiety

NCT03118752
View directory record Official record
Conditions
Acute Coronary Syndrome, Heart Failure, Depression, Generalized Anxiety Disorder, Panic Disorder
Interventions
Collaborative Care
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
290 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2024
U.S. locations
3
States / cities
Boston, Massachusetts • Salem, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 13, 2024 · Synced Oct 17, 2026, 8:53 PM EDT
Completed Not applicable Interventional

Improving Exercise Capacity With Tailored Physical Activity in Lymphoma & Breast Cancer Patients Undergoing Tx

NCT03923504
View directory record Official record
Conditions
Hodgkin Lymphoma, Non-hodgkin Lymphoma, Lymphoma, Breast Cancer
Interventions
Physical Activity Intervention (PAI), Healthy Living Control
Other
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years to 85 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
2
States / cities
Richmond, Virginia • South Hill, Virginia
Source: ClinicalTrials.gov public record
Updated Mar 7, 2023 · Synced Oct 17, 2026, 8:53 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

UPenn Observational Research Repository on Neurodegenerative Disease

NCT04715399
View directory record Official record
Conditions
Frontotemporal Degeneration(FTD), Primary Progressive Aphasia(PPA), Familial Frontotemporal Lobar Degeneration (fFTLD), Amyotrophic Lateral Sclerosis(ALS), Lewy Body Disease(LBD), Progressive Supranuclear Palsy(PSP), Corticobasal Syndrome(CBS), Posterior Cortical Atrophy(PCA), Alzheimer's Disease(AD)
Interventions
No intervention
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
1,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2070
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 22, 2026 · Synced Oct 17, 2026, 8:53 PM EDT
Completed Not applicable Interventional

Facilitating Alcohol Screening and Treatment (FAST)

NCT04303676
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Virtual Practice Facilitation with e-Learning, Virtual Practice Facilitation without e-Learning
Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 89 Years
Enrollment
399 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Dec 18, 2023 · Synced Oct 17, 2026, 8:53 PM EDT
Completed Not applicable Interventional Results available

Management Strategies for Patients With Low Back Pain and Sciatica

NCT02391350
View directory record Official record
Conditions
Low Back Pain, Sciatica, Physical Therapy
Interventions
Education and re-assurance, Physical Therapy
Behavioral · Procedure
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 60 Years
Enrollment
220 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jan 22, 2021 · Synced Oct 17, 2026, 8:53 PM EDT
Recruiting Not applicable Interventional

A Pilot Feasibility and Acceptability Study of Remote ExerciSe Training mOdalities (PRESTO)

NCT06931470
View directory record Official record
Conditions
Cardiovascular Diseases
Interventions
In-person supervised exercise sessions, Virtual classes (live-streamed sessions), Self-directed aerobic exercise, Myzone mobile application, Map My Fitness mobile application, Centralized telemetry, Myzone heart rate monitor
Behavioral · Device
Lead sponsor
NYU Langone Health
Other
Eligibility
45 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 5, 2026 · Synced Oct 17, 2026, 8:53 PM EDT
Completed No phase listed Observational

Improving Signout Accuracy and Information Delivery in the Emergency Department

NCT01859286
View directory record Official record
Conditions
Medical Errors Related to Emergency Department Sign Out
Interventions
standardized sign out process
Other
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
Not listed
Enrollment
321 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2012
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 21, 2013 · Synced Oct 17, 2026, 8:53 PM EDT
Recruiting Not applicable Interventional

The REPOSE (Reach for Equity in Pediatric Sleep Evaluation) Navigation Intervention

NCT06828835
View directory record Official record
Conditions
Sleep Apnea, Obstructive
Interventions
Reach for Equity in Pediatric Obstructive Sleep Evaluation (REPOSE), Usual Care
Other
Lead sponsor
Medical University of South Carolina
Other
Eligibility
2 Years to 12 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Feb 5, 2026 · Synced Oct 17, 2026, 8:53 PM EDT
Recruiting Phase 2 Interventional

An Investigational Scan (18F-DOPA PET/CT) for Improving the Clinical Management of Brain Tumors

NCT06667726
View directory record Official record
Conditions
Malignant Brain Neoplasm
Interventions
Computed Tomography, Fluorodopa F 18, Positron Emission Tomography
Procedure · Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
47 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 28, 2026 · Synced Oct 17, 2026, 8:53 PM EDT
Completed Not applicable Interventional Results available

MRI in Detecting Heart Damage in Patients With Cancer Receiving Chemotherapy With Exercise Capacity Addendum

NCT01719562
View directory record Official record
Conditions
Cardiac Toxicity, Malignant Neoplasm, Breast Cancer
Interventions
Magnetic resonance imaging, Physical Activity, Healthy Living, Cardiopulmonary Exercise Testing (CPET), Questionnaire Administration
Procedure · Other · Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 85 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2022
U.S. locations
2
States / cities
Winston-Salem, North Carolina • Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated May 19, 2023 · Synced Oct 17, 2026, 8:53 PM EDT
Completed Not applicable Interventional

Stepped Enhancement of PTSD Services Using Primary Care (STEPS UP): A Randomized Effectiveness Trial

NCT01492348
View directory record Official record
Conditions
Posttraumatic Stress Disorder (PTSD), Depression
Interventions
STEPS UP, OUC
Behavioral
Lead sponsor
Henry M. Jackson Foundation for the Advancement of Military Medicine
Other
Eligibility
18 Years to 65 Years
Enrollment
666 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
6
States / cities
Fort Carson, Colorado • Fort Stewart, Georgia • Fort Campbell, Kentucky + 3 more
Source: ClinicalTrials.gov public record
Updated Mar 14, 2017 · Synced Oct 17, 2026, 8:53 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Population-Based Patient-Centric Care: Comprehensive Preventive Cancer Screening Using Health IT

NCT01372527
View directory record Official record
Conditions
Breast Cancer, Colorectal Cancer, Cervical Cancer
Interventions
TopCare: Use of provider knowledge vs. automated system
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
21 Years to 75 Years
Enrollment
103,870 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 3, 2014 · Synced Oct 17, 2026, 8:53 PM EDT
Completed Phase 4 Interventional Results available

Health Systems Reach Interventions Project

NCT04199117
View directory record Official record
Conditions
Smoking, Cigarette, Smoking Cessation
Interventions
Varenicline, Combination nicotine patch and nicotine mini-lozenge treatment, Monetary incentives for initiating treatment, Automated tailored outreach, Care management, Wisconsin Tobacco Quit Line referral, Primary care provider referral, Untailored outreach, Multiple smoking cessation coaching calls
Drug · Behavioral · Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
210 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Oct 5, 2026 · Synced Oct 17, 2026, 8:53 PM EDT
Recruiting Not applicable Interventional

Systematic Implementation of Patient-centered Care for Alcohol Use Trial: Beyond Referral to Treatment

NCT06318026
View directory record Official record
Conditions
Alcohol Use Disorder, Unhealthy Alcohol Use
Interventions
Centralized Intervention, Primary Care Intervention
Behavioral · Other
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years and older
Enrollment
1,500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated May 6, 2025 · Synced Oct 17, 2026, 8:53 PM EDT
Completed Not applicable Interventional Results available

Increasing Live Donor Kidney Transplantation Through Video-based Education and Mobile Communication

NCT05154773
View directory record Official record
Conditions
End-stage Renal Disease, Chronic Kidney Diseases
Interventions
Kidney donation and transplant information made easy
Behavioral
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
Not listed
Enrollment
422 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated May 12, 2026 · Synced Oct 17, 2026, 8:53 PM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Evaluating the Impact of Centralized Interventions on Lung Cancer Screening Adherence in Community Settings, ACCELL Trial

NCT06324110
View directory record Official record
Conditions
Lung Carcinoma
Interventions
Electronic Health Record Review, Interview, Patient Navigation
Other · Behavioral
Lead sponsor
Fred Hutchinson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
6,772 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated May 18, 2026 · Synced Oct 17, 2026, 8:53 PM EDT
Completed Not applicable Interventional

Reducing Antimicrobial Overuse Through Targeted Therapy for Patients With Community-Acquired Pneumonia

NCT05568654
View directory record Official record
Conditions
Community-Acquired Pneumonia, Antimicrobial Stewardship, Point-of-Care Testing
Interventions
Rapid Diagnostic Testing, Pharmacist-led de-escalation
Diagnostic Test · Other
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
28,580 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
12
States / cities
Vero Beach, Florida • Weston, Florida • Akron, Ohio + 8 more
Source: ClinicalTrials.gov public record
Updated Jul 1, 2026 · Synced Oct 17, 2026, 8:53 PM EDT
Recruiting Not applicable Interventional

Hub-Based Engagement Navigator Service to Reduce CSC Disengagement

NCT06583239
View directory record Official record
Conditions
Disengagement
Interventions
Engagement Navigator Service (ENS)
Other
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
13 Years to 35 Years
Enrollment
555 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated May 28, 2026 · Synced Oct 17, 2026, 8:53 PM EDT
Completed No phase listed Observational

Implementation of a Population Health Chronic Disease Management Program

NCT02812303
View directory record Official record
Conditions
Diabetes Mellitus, Cardiovascular Diseases, Hypertension
Interventions
Centralized support for population health management activities
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
108,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 24, 2016 · Synced Oct 17, 2026, 8:53 PM EDT