- Conditions
- Postdural Puncture Headache, Epidural Analgesia, Obstetric
- Interventions
- EpiZact-assisted epidural placement
- Device
- Lead sponsor
- Oregon Health and Science University
- Other
- Eligibility
- 15 Years to 50 Years · Female only
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2026
- U.S. locations
- 1
- States / cities
- Portland, Oregon
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Showing 1–24
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- Conditions
- Ventilator Associated Pneumonia
- Interventions
- Toothbrushing only, Chlorhexidine only, Toothbrushing and Chlorhexidine
- Procedure
- Lead sponsor
- Virginia Commonwealth University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 547 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2002 – 2008
- U.S. locations
- 1
- States / cities
- Richmond, Virginia
- Conditions
- Cystic Fibrosis, Methicillin-resistant Staphylococcus Aureus
- Interventions
- Rifampin, Trimethoprim/Sulfamethoxazole, Minocycline, Mupirocin, chlorhexidine gluconate oral rinse, 2% Chlorhexidine solution wipes, Environmental Decontamination
- Drug · Behavioral
- Lead sponsor
- University of North Carolina, Chapel Hill
- Other
- Eligibility
- 4 Years to 45 Years
- Enrollment
- 47 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2015
- U.S. locations
- 13
- States / cities
- Birmingham, Alabama • Aurora, Colorado • Gainesville, Florida + 9 more
- Conditions
- Lentigines
- Interventions
- Enlighten Laser, Excel V Laser
- Device
- Lead sponsor
- Cutera Inc.
- Industry
- Eligibility
- 30 Years to 90 Years
- Enrollment
- 24 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2016 – 2017
- U.S. locations
- 1
- States / cities
- Naperville, Illinois
- Conditions
- Line Insertion Site, Central Line-associated Bloodstream Infection (CLABSI)
- Interventions
- Povidone-Iodine, Chlorhexidine gluconate, Pluronic Cream, control
- Drug · Other
- Lead sponsor
- University of Virginia
- Other
- Eligibility
- Up to 7 Days
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2014
- U.S. locations
- 1
- States / cities
- Charlottesville, Virginia
- Conditions
- Chronic Kidney Disease, Chronic Periodontitis, Generalized, Moderate
- Interventions
- dental intervention
- Procedure
- Lead sponsor
- Augusta University
- Other
- Eligibility
- 21 Years to 75 Years
- Enrollment
- 11 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018 – 2022
- U.S. locations
- 1
- States / cities
- Augusta, Georgia
- Conditions
- Major Depressive Disorder
- Interventions
- Auricular Acupuncture, Sham Auricular Acupuncture + Lexapro
- Device · Drug
- Lead sponsor
- Florida Gulf Coast University
- Other
- Eligibility
- 18 Years to 24 Years
- Enrollment
- 13 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2016
- U.S. locations
- 1
- States / cities
- Fort Myers, Florida
- Conditions
- Surgery
- Interventions
- Chlorhexidine Gluconate, Vehicle, DynaHex-2
- Drug · Other
- Lead sponsor
- Medline Industries
- Industry
- Eligibility
- 16 Years and older
- Enrollment
- 347 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2014 – 2015
- U.S. locations
- 1
- States / cities
- Sterling, Virginia
- Conditions
- Pain, Postoperative
- Interventions
- Ibuprofen 600 mg, Local anesthetic Group 1, Placebo oral capsule, Local anesthetic Control
- Drug
- Lead sponsor
- Satheesh Elangovan
- Other
- Eligibility
- 18 Years to 64 Years
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2017
- U.S. locations
- 1
- States / cities
- Iowa City, Iowa
- Conditions
- Oral Squamous Cell Carcinoma, Oral Cancer, Head and Neck Cancer, Head and Neck Carcinoma
- Interventions
- Metronidazole, Chlorhexidine
- Drug · Other
- Lead sponsor
- Case Comprehensive Cancer Center
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2027
- U.S. locations
- 1
- States / cities
- Cleveland, Ohio
- Conditions
- Surgical Site Infection, Unplanned Fracture-Related Reoperation, Open Appendicular Fracture
- Interventions
- 10% povidone-iodine (1% free iodine) in purified water, 4% chlorhexidine gluconate (CHG) in purified water
- Drug
- Lead sponsor
- University of Maryland, Baltimore
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 1,638 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2022
- U.S. locations
- 11
- States / cities
- Phoenix, Arizona • Tucson, Arizona • San Francisco, California + 8 more
- Conditions
- Surgical Site Infection
- Interventions
- IrriSept System, No Intervention - Standard of Care (SoC) only
- Device · Other
- Lead sponsor
- Irrimax Corporation
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 627 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2017
- U.S. locations
- 17
- States / cities
- Tucson, Arizona • Los Angeles, California • Denver, Colorado + 14 more
- Conditions
- Post-Op Complication, Spine Surgery, Site Infection, Surgical Site Infection, Spinal Instrumentation, Index Spinal Instrumentation, Layer-by-Layer Closure, Locoregional Flap-Based Closure
- Interventions
- Chlorhexidine gluconate solution, Vancomycin
- Device · Drug
- Lead sponsor
- Rhode Island Hospital
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 200 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2028
- U.S. locations
- 1
- States / cities
- Providence, Rhode Island
- Conditions
- Cutibacterium Acnes Contamination
- Interventions
- Irrisept Irrigation, Saline Irrigation Solution Delivery
- Procedure
- Lead sponsor
- Orthopaedic Education and Research Institute (dba Hoag Orthopedics)
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 126 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2024 – 2027
- U.S. locations
- 1
- States / cities
- Orange, California
- Conditions
- Preoperative Skin Preparation
- Interventions
- Chlorhexidine gluconate, N,N'-(1,10-decanediyldi-1(4H)-Pyridinyl-4-ylidene)-Bis-(1-octanamine) Dihydrochloride, Placebo
- Drug
- Lead sponsor
- C. R. Bard
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 145 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2016 – 2017
- U.S. locations
- 1
- States / cities
- Butte, Montana
- Conditions
- Bilateral Hearing Loss, Healthy Aging
- Interventions
- Gait assessment, Cognitive assessment
- Other
- Lead sponsor
- New York University
- Other
- Eligibility
- 40 Years and older
- Enrollment
- 67 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2022 – 2024
- U.S. locations
- 2
- States / cities
- New York, New York
- Conditions
- COVID-19
- Interventions
- Saline oral/nasal rinse, 0.5% Povidone/Iodine oral/nasal rinse, 0.12% Chlorhexidine oral/nasal rinse
- Drug
- Lead sponsor
- NYU Langone Health
- Other
- Eligibility
- 18 Years to 79 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Difficult Intravenous Access, Midline Catheter, Peripheral Intravenous Catheter, Emergency Department Patient
- Interventions
- 10-cm Single Lumen Mildine, 4.78 cm Long Peripheral Intravenous Catheter
- Device
- Lead sponsor
- Albany Medical College
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 270 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2026
- U.S. locations
- 1
- States / cities
- Albany, New York
- Conditions
- Erythematotelangiectatic Rosacea, Papulopustular Rosacea
- Interventions
- 532nm KTP Laser vs 595nm Pulse Dye Laser
- Device
- Lead sponsor
- Cutera Inc.
- Industry
- Eligibility
- 20 Years to 80 Years · Female only
- Enrollment
- 22 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2014 – 2015
- U.S. locations
- 1
- States / cities
- Miami, Florida
- Conditions
- Port-Wine Stain
- Interventions
- Cutera excel V™ Laser
- Device
- Lead sponsor
- Massachusetts General Hospital
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 10 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2020
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Abscesses, Furunculosis, Staphylococcus Aureus, Staphylococcal Skin Infections
- Interventions
- Mupirocin ointment, Chlorhexidine showers, Bleach baths (dilute), Intensive education on personal hygiene
- Drug · Genetic · Procedure + 1 more
- Lead sponsor
- Washington University School of Medicine
- Other
- Eligibility
- 6 Months and older
- Enrollment
- 300 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2010
- U.S. locations
- 2
- States / cities
- St Louis, Missouri
- Conditions
- Cystic Fibrosis
- Interventions
- Inhaled Vancomycin, Placebo (Sterile Water), Rifampin, Trimethoprim/Sulfamethoxazole (TMP/SMX), Doxycycline, Mupirocin Intranasal Creme, 4% chlorhexidine gluconate liquid skin cleanser
- Drug
- Lead sponsor
- Johns Hopkins University
- Other
- Eligibility
- 12 Years and older
- Enrollment
- 29 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2017
- U.S. locations
- 2
- States / cities
- Baltimore, Maryland • Cleveland, Ohio
- Conditions
- Arthroplasty Replacement, Knee, Arthroplasty Total Hip Replacement
- Interventions
- 3M™ Ioban™ CHG Chlorhexidine Gluconate Incise Drape (2% w/w CHG)
- Device
- Lead sponsor
- Solventum US LLC
- Industry
- Eligibility
- 22 Years and older
- Enrollment
- 179 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026
- U.S. locations
- 2
- States / cities
- Fishers, Indiana • Salt Lake City, Utah
- Conditions
- Chronic Periodontitis, Type 2 Diabetes
- Interventions
- Non-surgical periodontal therapy, Delayed non-surgical periodontal therapy
- Procedure · Other
- Lead sponsor
- Stony Brook University
- Other
- Eligibility
- 35 Years and older
- Enrollment
- 514 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2012
- U.S. locations
- 8
- States / cities
- Birmingham, Alabama • Minneapolis, Minnesota • Stony Brook, New York + 2 more